JP2015531351A5 - - Google Patents
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- Publication number
- JP2015531351A5 JP2015531351A5 JP2015533237A JP2015533237A JP2015531351A5 JP 2015531351 A5 JP2015531351 A5 JP 2015531351A5 JP 2015533237 A JP2015533237 A JP 2015533237A JP 2015533237 A JP2015533237 A JP 2015533237A JP 2015531351 A5 JP2015531351 A5 JP 2015531351A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- substituted
- unsubstituted
- fluorophenyl
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 *N(*Nc([o]c([Al])c1O)c1O)I Chemical compound *N(*Nc([o]c([Al])c1O)c1O)I 0.000 description 3
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261704014P | 2012-09-21 | 2012-09-21 | |
| US61/704,014 | 2012-09-21 | ||
| PCT/US2013/061050 WO2014047519A2 (en) | 2012-09-21 | 2013-09-20 | Inhibitors of beta-hydrolase for treatment of cancer |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015531351A JP2015531351A (ja) | 2015-11-02 |
| JP2015531351A5 true JP2015531351A5 (cg-RX-API-DMAC10.html) | 2016-11-10 |
| JP6469009B2 JP6469009B2 (ja) | 2019-02-13 |
Family
ID=50342080
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015533237A Expired - Fee Related JP6469009B2 (ja) | 2012-09-21 | 2013-09-20 | がん処置用β−ヒドロキシラーゼ阻害剤 |
Country Status (10)
| Country | Link |
|---|---|
| US (8) | US9771356B2 (cg-RX-API-DMAC10.html) |
| EP (2) | EP3345596B1 (cg-RX-API-DMAC10.html) |
| JP (1) | JP6469009B2 (cg-RX-API-DMAC10.html) |
| KR (1) | KR102137180B1 (cg-RX-API-DMAC10.html) |
| CN (2) | CN110818660B (cg-RX-API-DMAC10.html) |
| AU (1) | AU2013317791B2 (cg-RX-API-DMAC10.html) |
| CA (1) | CA2885762C (cg-RX-API-DMAC10.html) |
| ES (2) | ES2865412T3 (cg-RX-API-DMAC10.html) |
| HK (1) | HK1208805A1 (cg-RX-API-DMAC10.html) |
| WO (2) | WO2014047519A2 (cg-RX-API-DMAC10.html) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3345596B1 (en) | 2012-09-21 | 2021-01-20 | Rhode Island Hospital | Inhibitors of beta-hydrolase for treatment of cancer |
| WO2019012159A1 (en) * | 2017-07-14 | 2019-01-17 | Protea Biopharma N.V. | METHODS AND MEANS FOR DIAGNOSING AND / OR TREATING A FATIGUE-ASSOCIATED DISEASE |
| WO2019246093A1 (en) * | 2018-06-18 | 2019-12-26 | Midwestern University | Monoclonal antibodies targeting epitopes of asph |
| CN109364251A (zh) * | 2018-12-06 | 2019-02-22 | 苏州大学 | Tet蛋白在治疗抑郁症中的应用 |
| KR20210129115A (ko) * | 2019-02-15 | 2021-10-27 | 미드웨스턴 유니버시티 | 동위원소-안정화된 테트론이미드 화합물 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE39717C (de) | H. LEHMANN in München, Enhuberstr. 5 part | Bleistifthalter | ||
| DD39717A (cg-RX-API-DMAC10.html) * | ||||
| JPS63500375A (ja) * | 1985-08-02 | 1988-02-12 | シエブロン リサ−チ カンパニ− | 除草性２−（オクサまたはチアヘテロサイクル）５−アミノ−３−オクソ−４−（置換−フェニル）−２、３−ジヒドロフラン類 |
| US5314913A (en) * | 1992-12-08 | 1994-05-24 | American Home Products Corporation | 4- or 5-(substituted sulfonyl)methyl-3(2H)-furanones |
| US5698585A (en) * | 1995-04-13 | 1997-12-16 | Kikkoman Corporation | Pharmaceutical preparation for prevention and/or treatment for cataract |
| JPH09110853A (ja) * | 1995-10-12 | 1997-04-28 | Kikkoman Corp | ４‐アシルオキシフラノン誘導体又はその塩及びその製造方法 |
| UA57002C2 (uk) | 1995-10-13 | 2003-06-16 | Мерк Фросст Кенада Енд Ко./Мерк Фросст Кенада Енд Сі. | Похідне (метилсульфоніл)феніл-2-(5н)-фуранону, фармацевтична композиція та спосіб лікування |
| WO1998041516A1 (en) | 1997-03-14 | 1998-09-24 | Merck Frosst Canada & Co. | (methylsulfonyl)phenyl-2-(5h)-furanones with oxygen link as cox-2 inhibitors |
| US5877193A (en) * | 1996-07-19 | 1999-03-02 | Hoffmann-La Roche Inc. | Use of N-(4-aryl-thiazol-2-yl)-sulfonamides |
| TW528755B (en) * | 1996-12-24 | 2003-04-21 | Glaxo Group Ltd | 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives |
| US6835370B2 (en) | 1999-11-08 | 2004-12-28 | Rhode Island Hospital | Diagnosis and treatment of malignant neoplasms |
| US20050123545A1 (en) | 1999-11-08 | 2005-06-09 | Wands Jack R. | Diagnosis and treatment of malignant neoplasms |
| US20030031670A1 (en) | 1999-11-08 | 2003-02-13 | Jack R. Wands | Diagnosis and treatment of malignant neoplasms |
| WO2003018575A1 (en) * | 2001-08-24 | 2003-03-06 | Wyeth Holdings Corporation | 5-substituted-3(2h)-furanones useful for inhibition of farnesyl-protein transferase |
| US6667330B2 (en) * | 2002-01-31 | 2003-12-23 | Galileo Pharmaceuticals, Inc. | Furanone derivatives |
| AU2002950862A0 (en) | 2002-08-19 | 2002-09-12 | Biosignal Pty Ltd | Furanone derivatives and methods of making same |
| EP1554394B1 (en) | 2002-10-16 | 2009-12-16 | Isis Innovation Limited | Screening methods using a structural model of FIH |
| WO2005070916A1 (en) * | 2004-01-09 | 2005-08-04 | Eli Lilly And Company | Thiophene and furan compounds |
| WO2009073620A2 (en) | 2007-11-30 | 2009-06-11 | Newlink Genetics | Ido inhibitors |
| EP2576532B1 (en) * | 2010-06-07 | 2018-07-18 | Novomedix, LLC | Furanyl compounds and the use thereof |
| EP3345596B1 (en) | 2012-09-21 | 2021-01-20 | Rhode Island Hospital | Inhibitors of beta-hydrolase for treatment of cancer |
-
2013
- 2013-09-20 EP EP17202827.6A patent/EP3345596B1/en not_active Not-in-force
- 2013-09-20 EP EP13838498.7A patent/EP2897607B1/en not_active Not-in-force
- 2013-09-20 ES ES17202827T patent/ES2865412T3/es active Active
- 2013-09-20 HK HK15109523.0A patent/HK1208805A1/xx unknown
- 2013-09-20 CN CN201910949656.0A patent/CN110818660B/zh not_active Expired - Fee Related
- 2013-09-20 WO PCT/US2013/061050 patent/WO2014047519A2/en not_active Ceased
- 2013-09-20 AU AU2013317791A patent/AU2013317791B2/en not_active Ceased
- 2013-09-20 WO PCT/US2013/060934 patent/WO2014047447A2/en not_active Ceased
- 2013-09-20 ES ES13838498.7T patent/ES2660822T3/es active Active
- 2013-09-20 CN CN201380061004.4A patent/CN104902889A/zh active Pending
- 2013-09-20 JP JP2015533237A patent/JP6469009B2/ja not_active Expired - Fee Related
- 2013-09-20 KR KR1020157010188A patent/KR102137180B1/ko not_active Expired - Fee Related
- 2013-09-20 US US14/430,101 patent/US9771356B2/en active Active
- 2013-09-20 CA CA2885762A patent/CA2885762C/en active Active
-
2017
- 2017-07-17 US US15/651,842 patent/US10106532B2/en active Active
- 2017-09-26 US US15/715,989 patent/US10710995B2/en active Active
-
2018
- 2018-09-14 US US16/131,275 patent/US10351555B2/en active Active
-
2019
- 2019-06-12 US US16/439,253 patent/US10787445B2/en active Active
-
2020
- 2020-06-02 US US16/890,680 patent/US20200361925A1/en not_active Abandoned
- 2020-09-23 US US17/029,127 patent/US20210032233A1/en not_active Abandoned
-
2022
- 2022-04-14 US US17/720,472 patent/US20220251076A1/en not_active Abandoned
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