JP2015529077A - フリーラジカルに誘発されるｄｎａ損傷を特徴とする病態に対する被験者の素因を決定する方法及びアッセイ製品 - Google Patents

フリーラジカルに誘発されるｄｎａ損傷を特徴とする病態に対する被験者の素因を決定する方法及びアッセイ製品 Download PDF

Info

Publication number
JP2015529077A
JP2015529077A JP2015530497A JP2015530497A JP2015529077A JP 2015529077 A JP2015529077 A JP 2015529077A JP 2015530497 A JP2015530497 A JP 2015530497A JP 2015530497 A JP2015530497 A JP 2015530497A JP 2015529077 A JP2015529077 A JP 2015529077A
Authority
JP
Japan
Prior art keywords
sample
electromagnetic radiation
cancer
whole blood
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2015530497A
Other languages
English (en)
Japanese (ja)
Inventor
アンダーソン ダイアナ
アンダーソン ダイアナ
ナジャフザデー モジガン
ナジャフザデー モジガン
クライヴ トーマス デンヤー モーガン
クライヴ トーマス デンヤー モーガン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Bradford
Original Assignee
University of Bradford
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Bradford filed Critical University of Bradford
Publication of JP2015529077A publication Critical patent/JP2015529077A/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/70—Mechanisms involved in disease identification
    • G01N2800/7004—Stress
    • G01N2800/7009—Oxidative stress
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/70—Mechanisms involved in disease identification
    • G01N2800/7023—(Hyper)proliferation
    • G01N2800/7028—Cancer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Ecology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2015530497A 2012-09-11 2013-09-10 フリーラジカルに誘発されるｄｎａ損傷を特徴とする病態に対する被験者の素因を決定する方法及びアッセイ製品 Pending JP2015529077A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1216174.1A GB201216174D0 (en) 2012-09-11 2012-09-11 Method of determining a predisposition to disease states characterised by free redical induced dna damage
GB1216174.1 2012-09-11
PCT/GB2013/052365 WO2014041340A1 (en) 2012-09-11 2013-09-10 Methods of, and assay products for, determining the predisposition of a subject to disease states characterised by free radical induced dna damage

Publications (1)

Publication Number Publication Date
JP2015529077A true JP2015529077A (ja) 2015-10-05

Family

ID=47137246

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015530497A Pending JP2015529077A (ja) 2012-09-11 2013-09-10 フリーラジカルに誘発されるｄｎａ損傷を特徴とする病態に対する被験者の素因を決定する方法及びアッセイ製品

Country Status (7)

Country Link
US (1) US20150219619A1 (https=)
EP (1) EP2895853A1 (https=)
JP (1) JP2015529077A (https=)
CN (1) CN104755927A (https=)
GB (1) GB201216174D0 (https=)
IN (1) IN2015DN02685A (https=)
WO (1) WO2014041340A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023546212A (ja) * 2020-10-22 2023-11-01 フォーディー ライフテック アーゲー がん及びがん易罹患性の検出のための新規なバイオマーカーとしてのｄｎａ損傷感受性

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9931634B2 (en) 2014-02-27 2018-04-03 The Regents Of The Univeristy Of California High throughput DNA damage quantification of human tissue with home-based collection device
US12000771B2 (en) * 2019-07-25 2024-06-04 Seoul Viosys Co., Ltd. Light irradiation apparatus

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1999274A2 (en) * 2006-03-02 2008-12-10 Laboratory Corporation of America Holdings Methods and systems for evaluating health risk factors by measurement of dna damage and dna repair

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023546212A (ja) * 2020-10-22 2023-11-01 フォーディー ライフテック アーゲー がん及びがん易罹患性の検出のための新規なバイオマーカーとしてのｄｎａ損傷感受性

Also Published As

Publication number Publication date
GB201216174D0 (en) 2012-10-24
WO2014041340A1 (en) 2014-03-20
CN104755927A (zh) 2015-07-01
IN2015DN02685A (https=) 2015-09-04
EP2895853A1 (en) 2015-07-22
US20150219619A1 (en) 2015-08-06

Similar Documents

Publication Publication Date Title
Liu et al. “Two birds with one stone” ruthenium (II) complex probe for biothiols discrimination and detection in vitro and in vivo
Oh et al. Fluorescent polymer nanoparticle for selective sensing of intracellular hydrogen peroxide
Yong et al. Gold‐nanorod‐assisted near‐infrared stimulation of primary auditory neurons
Moreddu Nanotechnology and cancer bioelectricity: bridging the gap between biology and translational medicine
Olive et al. Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the “comet” assay
Zheng et al. Optical detection of single cell lactate release for cancer metabolic analysis
Shi et al. A supersmall single-cell nanosensor for intracellular K+ detection
Choi et al. A two-photon ratiometric probe for hydrogen polysulfide (H2Sn): Increase in mitochondrial H2Sn production in a Parkinson’s disease model
Karimi et al. 3D melanoma spheroid model for the development of positronium biomarkers
Svitkova et al. Assessment of CdS quantum dots effect on UV damage to DNA using a DNA/quantum dots structured electrochemical biosensor and DNA biosensing in solution
Wang et al. Glass nanopipette-based plasmonic SERS platform for single-cell microRNA-21 sensing during apoptosis
Wang et al. In‐vivo two‐photon visualization and quantitative detection of redox state of cancer
Tong Biophoton signaling in mediation of cell-to-cell communication and radiation-induced bystander effects
JP2015529077A (ja) フリーラジカルに誘発されるｄｎａ損傷を特徴とする病態に対する被験者の素因を決定する方法及びアッセイ製品
Landra-Willm et al. A photoswitchable inhibitor of TREK channels controls pain in wild-type intact freely moving animals
CN103487425A (zh) 一种利用表面增强拉曼光谱判别癌细胞的方法
Marrot et al. Fluoroquinolones as chemical tools to define a strategy for photogenotoxicity in vitro assessment
CN105274195A (zh) 一种检测癌症标志物微小核糖核酸的试剂盒
Hintzsche et al. Micronucleus formation kinetics in buccal mucosa cells of head and neck cancer patients undergoing radiotherapy
Qu et al. Electrostimulus-associated PD-L1 expression on cell membrane revealed by immune SERS nanoprobes
CN106753337A (zh) 一种近红外及双光子双模式成像荧光探针及其制备和应用
Rizvi et al. Mind the gap: 3D models in photodynamic therapy
EP4232821B1 (en) Dna damage sensitivity as a new biomarker for detection of cancer and cancer susceptibility
Jian-Lin et al. Response of lymphocytes to radiation in untreated breast cancer patients as detected with three different genetic assays
Vaneev et al. Electrochemical detection and imaging of reactive oxygen species in single living cells