JP2015528443A5 - - Google Patents
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- JP2015528443A5 JP2015528443A5 JP2015526842A JP2015526842A JP2015528443A5 JP 2015528443 A5 JP2015528443 A5 JP 2015528443A5 JP 2015526842 A JP2015526842 A JP 2015526842A JP 2015526842 A JP2015526842 A JP 2015526842A JP 2015528443 A5 JP2015528443 A5 JP 2015528443A5
- Authority
- JP
- Japan
- Prior art keywords
- absent
- peptide
- sequence
- amino acids
- peptide according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 108090000765 processed proteins & peptides Proteins 0.000 claims 36
- 235000001014 amino acid Nutrition 0.000 claims 31
- 150000001413 amino acids Chemical class 0.000 claims 31
- 108700028369 Alleles Proteins 0.000 claims 6
- 102000008949 Histocompatibility Antigens Class I Human genes 0.000 claims 6
- 210000001744 T-lymphocyte Anatomy 0.000 claims 6
- 108010088652 Histocompatibility Antigens Class I Proteins 0.000 claims 5
- 102100028976 HLA class I histocompatibility antigen, B alpha chain Human genes 0.000 claims 4
- 108010058607 HLA-B Antigens Proteins 0.000 claims 4
- 239000004472 Lysine Substances 0.000 claims 3
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims 3
- 102100028972 HLA class I histocompatibility antigen, A alpha chain Human genes 0.000 claims 2
- 108010075704 HLA-A Antigens Proteins 0.000 claims 2
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 claims 2
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 claims 2
- KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 claims 2
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 claims 2
- 108700018351 Major Histocompatibility Complex Proteins 0.000 claims 2
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 claims 2
- KZSNJWFQEVHDMF-UHFFFAOYSA-N Valine Natural products CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 claims 2
- 210000004027 cell Anatomy 0.000 claims 2
- 229930182817 methionine Natural products 0.000 claims 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 2
- 230000020382 suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I Effects 0.000 claims 2
- 239000004474 valine Substances 0.000 claims 2
- 239000004475 Arginine Substances 0.000 claims 1
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 claims 1
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 claims 1
- 108091054437 MHC class I family Proteins 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 230000002378 acidificating effect Effects 0.000 claims 1
- 235000004279 alanine Nutrition 0.000 claims 1
- 230000000735 allogeneic effect Effects 0.000 claims 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 235000013922 glutamic acid Nutrition 0.000 claims 1
- 239000004220 glutamic acid Substances 0.000 claims 1
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 claims 1
- 230000002209 hydrophobic effect Effects 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 210000000130 stem cell Anatomy 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261683361P | 2012-08-15 | 2012-08-15 | |
| US61/683,361 | 2012-08-15 | ||
| US201361818040P | 2013-05-01 | 2013-05-01 | |
| US61/818,040 | 2013-05-01 | ||
| PCT/CA2013/050580 WO2014026277A1 (en) | 2012-08-15 | 2013-07-25 | Method for identifying novel minor histocompatibility antigens |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019067343A Division JP2019107034A (ja) | 2012-08-15 | 2019-03-29 | 新規マイナー組織適合抗原を同定するための方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015528443A JP2015528443A (ja) | 2015-09-28 |
| JP2015528443A5 true JP2015528443A5 (enExample) | 2016-09-15 |
Family
ID=50101152
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015526842A Pending JP2015528443A (ja) | 2012-08-15 | 2013-07-25 | 新規マイナー組織適合抗原を同定するための方法 |
| JP2019067343A Pending JP2019107034A (ja) | 2012-08-15 | 2019-03-29 | 新規マイナー組織適合抗原を同定するための方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019067343A Pending JP2019107034A (ja) | 2012-08-15 | 2019-03-29 | 新規マイナー組織適合抗原を同定するための方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US9500651B2 (enExample) |
| EP (2) | EP2867252B1 (enExample) |
| JP (2) | JP2015528443A (enExample) |
| CA (1) | CA2880331A1 (enExample) |
| WO (1) | WO2014026277A1 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11111543B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US11322224B2 (en) | 2010-05-18 | 2022-05-03 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US12152275B2 (en) | 2010-05-18 | 2024-11-26 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US20190010543A1 (en) | 2010-05-18 | 2019-01-10 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US9677118B2 (en) | 2014-04-21 | 2017-06-13 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11408031B2 (en) | 2010-05-18 | 2022-08-09 | Natera, Inc. | Methods for non-invasive prenatal paternity testing |
| US11939634B2 (en) | 2010-05-18 | 2024-03-26 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US12221653B2 (en) | 2010-05-18 | 2025-02-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US10316362B2 (en) | 2010-05-18 | 2019-06-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| RU2671980C2 (ru) | 2011-02-09 | 2018-11-08 | Натера, Инк. | Способы неинвазивного пренатального установления плоидности |
| US20140100126A1 (en) | 2012-08-17 | 2014-04-10 | Natera, Inc. | Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data |
| CN106460070B (zh) * | 2014-04-21 | 2021-10-08 | 纳特拉公司 | 检测染色体片段中的突变和倍性 |
| US12492429B2 (en) | 2014-04-21 | 2025-12-09 | Natera, Inc. | Detecting mutations and ploidy in chromosomal segments |
| EP3146078B1 (en) * | 2014-05-17 | 2019-11-27 | The Regents of the University of California | Centromere/kinetochore protein genes as markers for cancer diagnosis and prognosis and for treatment selection |
| US20180173846A1 (en) | 2014-06-05 | 2018-06-21 | Natera, Inc. | Systems and Methods for Detection of Aneuploidy |
| EP3256488A4 (en) * | 2015-02-09 | 2018-10-17 | Université de Montréal | Novel minor histocompatibility antigens and uses thereof |
| US11479812B2 (en) | 2015-05-11 | 2022-10-25 | Natera, Inc. | Methods and compositions for determining ploidy |
| GB201515321D0 (en) | 2015-08-28 | 2015-10-14 | Immatics Biotechnologies Gmbh | Novel peptides, combination of peptides and scaffolds for use in immunotherapeutic treatment of various cancers |
| PH12018501893A1 (en) | 2015-08-28 | 2022-05-02 | Immatics Biotechnologies Gmbh | Novel peptides, combination of peptides and scaffolds for use in immunotherapeutic treatment of various cancers |
| GB201521746D0 (en) * | 2015-12-10 | 2016-01-27 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against CLL and other cancers |
| ES2913468T3 (es) | 2016-04-15 | 2022-06-02 | Natera Inc | Métodos para la detección del cáncer de pulmón. |
| GB201618485D0 (en) | 2016-11-02 | 2016-12-14 | Ucl Business Plc | Method of detecting tumour recurrence |
| EP3585800A4 (en) * | 2017-02-22 | 2021-06-02 | The Universite de Montreal | Novel minor histocompatibility antigens and uses thereof |
| US12084720B2 (en) | 2017-12-14 | 2024-09-10 | Natera, Inc. | Assessing graft suitability for transplantation |
| JP7573443B2 (ja) | 2018-04-14 | 2024-10-25 | ナテラ， インコーポレイテッド | 循環腫瘍ｄｎａの個別化された検出を用いる癌検出およびモニタリングの方法 |
| US12234509B2 (en) | 2018-07-03 | 2025-02-25 | Natera, Inc. | Methods for detection of donor-derived cell-free DNA |
| CN112608365B (zh) * | 2020-12-22 | 2021-07-30 | 吉林省特医食品生物科技有限公司 | 一种减轻体重的发酵型小分子肽及其制备方法和应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040002068A1 (en) * | 2000-03-01 | 2004-01-01 | Corixa Corporation | Compositions and methods for the detection, diagnosis and therapy of hematological malignancies |
| WO2010116375A1 (en) * | 2009-04-08 | 2010-10-14 | Yeda Research And Development Co. Ltd. | Isolated peptides for regulating apoptosis |
-
2013
- 2013-07-25 EP EP13829855.9A patent/EP2867252B1/en active Active
- 2013-07-25 EP EP19212576.3A patent/EP3639831A1/en not_active Withdrawn
- 2013-07-25 JP JP2015526842A patent/JP2015528443A/ja active Pending
- 2013-07-25 WO PCT/CA2013/050580 patent/WO2014026277A1/en not_active Ceased
- 2013-07-25 CA CA2880331A patent/CA2880331A1/en not_active Abandoned
- 2013-07-25 US US14/421,310 patent/US9500651B2/en not_active Expired - Fee Related
-
2016
- 2016-10-20 US US15/299,387 patent/US10239917B2/en not_active Expired - Fee Related
-
2019
- 2019-03-29 JP JP2019067343A patent/JP2019107034A/ja active Pending
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