JP2015527341A5 - - Google Patents

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Publication number
JP2015527341A5
JP2015527341A5 JP2015525570A JP2015525570A JP2015527341A5 JP 2015527341 A5 JP2015527341 A5 JP 2015527341A5 JP 2015525570 A JP2015525570 A JP 2015525570A JP 2015525570 A JP2015525570 A JP 2015525570A JP 2015527341 A5 JP2015527341 A5 JP 2015527341A5
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JP
Japan
Prior art keywords
lung cancer
histology
cetuximab
determining
patient
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JP2015525570A
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English (en)
Japanese (ja)
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JP2015527341A (ja
JP6324381B2 (ja
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Priority claimed from PCT/US2013/053091 external-priority patent/WO2014028221A1/en
Publication of JP2015527341A publication Critical patent/JP2015527341A/ja
Publication of JP2015527341A5 publication Critical patent/JP2015527341A5/ja
Application granted granted Critical
Publication of JP6324381B2 publication Critical patent/JP6324381B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2015525570A 2012-07-31 2013-07-31 抗egfr薬物による処置のための非小細胞肺癌患者を同定するための組織学的マーカー Expired - Fee Related JP6324381B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CNPCT/CN2012/079399 2012-07-31
CN2012079399 2012-07-31
PCT/US2013/053091 WO2014028221A1 (en) 2012-07-31 2013-07-31 Histological markers for identifying non-small cell lung carcinoma patients for treatment with an anti-egfr drug

Publications (3)

Publication Number Publication Date
JP2015527341A JP2015527341A (ja) 2015-09-17
JP2015527341A5 true JP2015527341A5 (https=) 2016-07-07
JP6324381B2 JP6324381B2 (ja) 2018-05-16

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ID=50101405

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015525570A Expired - Fee Related JP6324381B2 (ja) 2012-07-31 2013-07-31 抗egfr薬物による処置のための非小細胞肺癌患者を同定するための組織学的マーカー

Country Status (5)

Country Link
US (1) US9921222B2 (https=)
EP (1) EP2879712B1 (https=)
JP (1) JP6324381B2 (https=)
ES (1) ES2668861T3 (https=)
WO (1) WO2014028221A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107073015B (zh) * 2014-09-16 2020-07-21 艾伯维公司 用于治疗吸烟者中的非小细胞肺癌的维利帕尼与卡铂和紫杉醇的组合
CN110520543A (zh) * 2017-03-29 2019-11-29 中美冠科生物技术(太仓)有限公司 确定胃癌对西妥昔单抗敏感性的系统和方法
CN112813164A (zh) * 2021-01-18 2021-05-18 四川省肿瘤医院 Ereg促进nsclc细胞对egfr-tki产生耐药性原因的验证方法

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AU4128089A (en) 1988-09-15 1990-03-22 Rorer International (Overseas) Inc. Monoclonal antibodies specific to human epidermal growth factor receptor and therapeutic methods employing same
US5942602A (en) 1997-02-13 1999-08-24 Schering Aktiengessellschaft Growth factor receptor antibodies
US6949245B1 (en) 1999-06-25 2005-09-27 Genentech, Inc. Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies
KR20110008112A (ko) 1999-08-27 2011-01-25 제넨테크, 인크. 항-ErbB2 항체 투여 치료 방법
EP1622941A2 (en) 2003-03-20 2006-02-08 ImClone Systems Incorporated Method of producing an antibody to epidermal growth factor receptor
CA2560305C (en) 2004-03-19 2016-07-05 Imclone Systems Incorporated Human anti-epidermal growth factor receptor antibody
CA2612183C (en) 2005-06-28 2015-08-11 Genentech, Inc. Egfr and kras mutations
DK1951759T3 (da) 2005-11-12 2010-05-10 Lilly Co Eli Anti-EGFR-antistoffer
WO2008140493A2 (en) 2006-11-21 2008-11-20 The Regents Of The University Of Californina Anti-egfr family antibodies, bispecific anti-egfr family antibodies and methods of use thereof
US7977336B2 (en) 2006-12-28 2011-07-12 Banyu Pharmaceutical Co. Ltd Aminopyrimidine derivatives as PLK1 inhibitors
KR100968591B1 (ko) 2007-06-14 2010-07-08 한국과학기술연구원 약물전달용 폴리포스파젠계 하이드로젤, 그의 제조방법 및그의 용도
US20100009390A1 (en) 2008-05-09 2010-01-14 The Regents Of The University Of California Mutant antibodies with high affinity for egfr
CN102164960A (zh) 2008-09-26 2011-08-24 罗氏格黎卡特股份公司 双特异性抗-egfr/抗-igf-1r抗体
WO2010080463A1 (en) 2008-12-18 2010-07-15 Imclone Llc Antibody humanization
KR101108642B1 (ko) 2009-09-29 2012-02-09 주식회사 녹십자 표피 성장 인자 수용체에 특이적으로 결합하는 항체
CA2777825A1 (en) 2009-10-28 2011-05-19 Abbott Biotherapeutics Corp. Anti-egfr antibodies and their uses
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BR112012013148A2 (pt) 2009-12-29 2017-03-21 F Hoffmann - La Roche Ag formulação farmacêutica e uso
JP2011144124A (ja) 2010-01-13 2011-07-28 Fujirebio Inc 活性型egfr特異抗体
EP2566512A1 (en) 2010-05-04 2013-03-13 Merrimack Pharmaceuticals, Inc. Antibodies against epidermal growth factor receptor (egfr) and uses thereof
WO2011140151A1 (en) 2010-05-04 2011-11-10 Dyax Corp. Antibodies against epidermal growth factor receptor (egfr)
JP5965838B2 (ja) 2010-06-04 2016-08-10 東亞合成株式会社 抗体およびその利用
WO2011156617A2 (en) 2010-06-09 2011-12-15 Aveo Pharmaceuticals, Inc. Anti-egfr antibodies
EP2603527A1 (en) 2010-08-10 2013-06-19 Glycotope GmbH Humanized egfr antibodies
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US8691231B2 (en) 2011-06-03 2014-04-08 Merrimack Pharmaceuticals, Inc. Methods of treatment of tumors expressing predominantly high affinity EGFR ligands or tumors expressing predominantly low affinity EGFR ligands with monoclonal and oligoclonal anti-EGFR antibodies

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