JP2015505959A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2015505959A5 JP2015505959A5 JP2014545002A JP2014545002A JP2015505959A5 JP 2015505959 A5 JP2015505959 A5 JP 2015505959A5 JP 2014545002 A JP2014545002 A JP 2014545002A JP 2014545002 A JP2014545002 A JP 2014545002A JP 2015505959 A5 JP2015505959 A5 JP 2015505959A5
- Authority
- JP
- Japan
- Prior art keywords
- subject
- cancer
- inhibitor
- group
- inhibitors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161567085P | 2011-12-05 | 2011-12-05 | |
| US61/567,085 | 2011-12-05 | ||
| US201261728748P | 2012-11-20 | 2012-11-20 | |
| US61/728,748 | 2012-11-20 | ||
| PCT/US2012/068005 WO2013086031A1 (en) | 2011-12-05 | 2012-12-05 | Method of therapy selection for patients with cancer |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017191195A Division JP2018054614A (ja) | 2011-12-05 | 2017-09-29 | 癌を有する患者に治療を選択する方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015505959A JP2015505959A (ja) | 2015-02-26 |
| JP2015505959A5 true JP2015505959A5 (https=) | 2016-01-28 |
Family
ID=48574842
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014545002A Pending JP2015505959A (ja) | 2011-12-05 | 2012-12-05 | 癌を有する患者に治療を選択する方法 |
| JP2017191195A Pending JP2018054614A (ja) | 2011-12-05 | 2017-09-29 | 癌を有する患者に治療を選択する方法 |
| JP2019182229A Pending JP2020024210A (ja) | 2011-12-05 | 2019-10-02 | 癌を有する患者に治療を選択する方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017191195A Pending JP2018054614A (ja) | 2011-12-05 | 2017-09-29 | 癌を有する患者に治療を選択する方法 |
| JP2019182229A Pending JP2020024210A (ja) | 2011-12-05 | 2019-10-02 | 癌を有する患者に治療を選択する方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20140273006A1 (https=) |
| EP (1) | EP2788752B1 (https=) |
| JP (3) | JP2015505959A (https=) |
| WO (1) | WO2013086031A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016502974A (ja) * | 2012-12-07 | 2016-02-01 | ザ ジェネラル ホスピタル コーポレイション | Pi3k/akt阻害剤化合物とher3/egfr阻害剤化合物との組み合わせ及び高増殖性疾患の治療におけるその使用 |
| MX2015010854A (es) * | 2013-03-14 | 2016-07-20 | Genentech Inc | Combinaciones de un compuesto inhibidor de mek con un compuesto inhibidor de her3/egfr y metodos de uso. |
| EP3087394A2 (en) | 2013-12-27 | 2016-11-02 | Merrimack Pharmaceuticals, Inc. | Biomarker profiles for predicting outcomes of cancer therapy with erbb3 inhibitors and/or chemotherapies |
| EP3107578A2 (en) * | 2014-02-20 | 2016-12-28 | Merrimack Pharmaceuticals, Inc. | Dosage and administration of anti-igf-1r, anti-erbb3 bispecific antibodies, uses thereof and methods of treatment therewith |
| WO2016011558A1 (en) * | 2014-07-23 | 2016-01-28 | Ontario Institute For Cancer Research | Systems, devices and methods for constructing and using a biomarker |
| CN107003300B (zh) * | 2014-12-12 | 2020-02-07 | 凯尔科迪股份有限公司 | 测量erbb信号传导通路活性以诊断和治疗癌症患者的方法 |
| ES3007999T3 (en) * | 2015-04-21 | 2025-03-21 | Genentech Inc | Compositions and methods for prostate cancer analysis |
| US10184006B2 (en) | 2015-06-04 | 2019-01-22 | Merrimack Pharmaceuticals, Inc. | Biomarkers for predicting outcomes of cancer therapy with ErbB3 inhibitors |
| HK1249866A1 (zh) * | 2015-06-29 | 2018-11-16 | 豪夫迈‧罗氏有限公司 | 用他塞利昔布进行治疗的方法 |
| EP3363911B1 (en) * | 2015-10-14 | 2024-09-25 | Nitto Boseki Co., Ltd. | Method for determining drug-sensitive human breast cancer cells by analysis method in which measurement of activity of two types of protein kinase is used |
| KR20190015360A (ko) * | 2016-05-31 | 2019-02-13 | 네스텍 소시에테아노님 | Her2 및 her3 경로 아형 분류를 기반으로 한, 유방암 환자에 대한 약물 치료법의 선택 방법 |
| US20180117029A1 (en) * | 2016-11-03 | 2018-05-03 | Beth Israel Deaconess Medical Center, Inc. | Targeting Metabolic Vulnerability in Triple-Negative Breast Cancer |
| MX2019011769A (es) | 2017-04-03 | 2019-11-07 | Hoffmann La Roche | Anticuerpos que se unen a steap-1. |
| CN113683700B (zh) * | 2017-06-22 | 2023-05-02 | 北海康成(北京)医药科技有限公司 | 预测食管癌对抗erbb3抗体治疗的应答的方法和试剂盒 |
| WO2020081956A1 (en) * | 2018-10-18 | 2020-04-23 | Medimmune, Llc | Methods for determining treatment for cancer patients |
| KR102267593B1 (ko) * | 2018-10-19 | 2021-06-21 | 주식회사 프로티나 | Her2 및 her3의 헤테로다이머를 표적으로 하는 약물 및 이의 스크리닝 방법 |
| CN111888487B (zh) * | 2020-09-04 | 2022-05-17 | 山西医科大学 | 肿瘤靶向型光声成像引导多阶段治疗纳米探针及制备方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5532138A (en) | 1990-04-26 | 1996-07-02 | Behringwerke Ag | Method and kits for determining peroxidatively active catalysts |
| US5332662A (en) | 1992-07-31 | 1994-07-26 | Syntex (U.S.A.) Inc. | Methods for determining peroxidatively active substances |
| WO1995006877A1 (en) | 1993-09-03 | 1995-03-09 | Behringwerke Ag | Fluorescent oxygen channeling immunoassays |
| AU2005265214A1 (en) * | 2004-06-21 | 2006-01-26 | Exelixis, Inc. | P4HAS as modifiers of the IGFR pathway and methods of use |
| NZ575827A (en) | 2006-09-21 | 2012-02-24 | Prometheus Lab Inc | Antibody-based arrays for detecting multiple signal transducers in rare circulating cells |
| BRPI0717416A2 (pt) | 2006-09-21 | 2013-11-12 | Prometheus Lab Inc | Método para realizar um imunoensaio complexo de alta produtividade, e, arranjo |
| EP2179291B1 (en) * | 2007-07-13 | 2014-10-22 | Nestec S.A. | Drug selection for lung cancer therapy using antibody-based arrays |
| EP2235536A4 (en) * | 2007-12-20 | 2011-05-04 | Lab Corp America Holdings | HER-2-DIAGNOSTIC PROCEDURE |
| AU2009219437B2 (en) | 2008-02-25 | 2014-10-16 | Nestec S.A. | Drug selection for breast cancer therapy using antibody-based arrays |
| US20100233733A1 (en) * | 2009-02-10 | 2010-09-16 | Nodality, Inc., A Delaware Corporation | Multiple mechanisms for modulation of the pi3 kinase pathway |
| NZ596468A (en) | 2009-05-14 | 2013-11-29 | Nestec Sa | Biomarkers for determining sensitivity of breast cancer cells to her2-targeted therapy |
| JP5795311B2 (ja) | 2009-07-15 | 2015-10-14 | ネステク ソシエテ アノニム | 抗体ベースのアレイを使用する胃癌療法のための薬物選択 |
| DK2491385T3 (en) | 2009-10-20 | 2017-08-28 | Diatech Holdings Inc | PROXIMITY-MEDIED ASSAYS FOR DETECTING ONCOGEN FUSION PROTEINS |
| BR112012017084A2 (pt) * | 2010-01-12 | 2016-04-12 | Nestec Sa | métodos para previsão de resposta de câncer de mama triplo-negativo à terapia |
| US20110217701A1 (en) * | 2010-03-03 | 2011-09-08 | Carter Scott L | Prognostic Marker for Endometrial Carcinoma |
| SG191230A1 (en) * | 2010-12-23 | 2013-07-31 | Nestec Sa | Drug selection for malignant cancer therapy using antibody-based arrays |
| EP2681552A2 (en) * | 2011-03-02 | 2014-01-08 | Nestec S.A. | Prediction of drug sensitivity of lung tumors based on molecular and genetic signatures |
-
2012
- 2012-12-05 WO PCT/US2012/068005 patent/WO2013086031A1/en not_active Ceased
- 2012-12-05 EP EP12855900.2A patent/EP2788752B1/en active Active
- 2012-12-05 JP JP2014545002A patent/JP2015505959A/ja active Pending
-
2014
- 2014-06-03 US US14/294,449 patent/US20140273006A1/en not_active Abandoned
-
2017
- 2017-09-29 JP JP2017191195A patent/JP2018054614A/ja active Pending
-
2019
- 2019-10-02 JP JP2019182229A patent/JP2020024210A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2015505959A5 (https=) | ||
| Cohen | Current challenges and clinical investigations of epidermal growth factor receptor (EGFR)-and ErbB family-targeted agents in the treatment of head and neck squamous cell carcinoma (HNSCC) | |
| Leto et al. | Primary and acquired resistance to EGFR-targeted therapies in colorectal cancer: impact on future treatment strategies | |
| Qi et al. | Expression features of CXCR5 and its ligand, CXCL13 associated with poor prognosis of advanced colorectal cancer | |
| Grünwald et al. | Depth of remission is a prognostic factor for survival in patients with metastatic renal cell carcinoma | |
| EA201200025A1 (ru) | Биомаркеры и способы определения эффективности анти-egfr антител для лечения злокачественного новообразования | |
| Groen et al. | A randomized, double-blind, phase II study of erlotinib with or without sunitinib for the second-line treatment of metastatic non-small-cell lung cancer (NSCLC) | |
| RU2012134390A (ru) | Способы предсказания ответа трижды негативного рака молочной железы на терапию | |
| RU2017125053A (ru) | Терапевтические, диагностические и прогностические способы для рака мочевого пузыря | |
| Skoura et al. | Role of positron emission tomography in the early prediction of response to chemotherapy in patients with non–small-cell lung cancer | |
| RU2012109556A (ru) | Биологические маркеры для мониторирования ответа пациента на антагонисты vegf | |
| Machiels et al. | Activity and safety of afatinib in a window preoperative EORTC study in patients with squamous cell carcinoma of the head and neck (SCCHN) | |
| Bencsikova et al. | Efficacy of bevacizumab and chemotherapy in the first-line treatment of metastatic colorectal cancer: broadening KRAS-focused clinical view | |
| Peng et al. | Optimize the cycle of neoadjuvant chemotherapy for locoregionally advanced nasopharyngeal carcinoma treated with intensity-modulated radiotherapy: a propensity score matching analysis | |
| Peták et al. | Integrating molecular diagnostics into anticancer drug discovery | |
| JP2014533960A5 (https=) | ||
| Milella et al. | EGFR molecular profiling in advanced NSCLC: a prospective phase II study in molecularly/clinically selected patients pretreated with chemotherapy | |
| Hatch et al. | Blood‐based markers of efficacy and resistance to cetuximab treatment in metastatic colorectal cancer: results from CALGB 80203 (Alliance) | |
| Dziadziuszko et al. | Epidermal growth factor receptor (EGFR) inhibitors and derived treatments | |
| Cetin et al. | Prognostic factors for overall survival in patients with metastatic colorectal carcinoma treated with vascular endothelial growth factor-targeting agents | |
| Sudhindra et al. | Biomarkers, prediction, and prognosis in non–small-cell lung cancer: a platform for personalized treatment | |
| RU2015140573A (ru) | Способы и композиции для обнаружения и лечения устойчивого к лекарственным средствам мутанта акт | |
| Baselga et al. | Using pharmacokinetic and pharmacodynamic data in early decision making regarding drug development: a phase I clinical trial evaluating tyrosine kinase inhibitor, AEE788 | |
| Moldvay | Personalized treatment in non-small cell lung cancer: from diagnostics to therapy | |
| EP2954068A1 (en) | Drug selection for non-small cell lung cancer therapy |