JP2015524467A5 - - Google Patents
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- Publication number
- JP2015524467A5 JP2015524467A5 JP2015526508A JP2015526508A JP2015524467A5 JP 2015524467 A5 JP2015524467 A5 JP 2015524467A5 JP 2015526508 A JP2015526508 A JP 2015526508A JP 2015526508 A JP2015526508 A JP 2015526508A JP 2015524467 A5 JP2015524467 A5 JP 2015524467A5
- Authority
- JP
- Japan
- Prior art keywords
- dose
- cancer
- lipoplatin
- drug
- administered
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 claims 32
- 206010028980 Neoplasm Diseases 0.000 claims 16
- 229940079593 drug Drugs 0.000 claims 16
- 201000011510 cancer Diseases 0.000 claims 8
- 239000003795 chemical substances by application Substances 0.000 claims 7
- 238000009097 single-agent therapy Methods 0.000 claims 6
- 208000003174 Brain Neoplasms Diseases 0.000 claims 5
- 206010009944 Colon cancer Diseases 0.000 claims 4
- 208000002154 non-small cell lung carcinoma Diseases 0.000 claims 4
- 208000029729 tumor suppressor gene on chromosome 11 Diseases 0.000 claims 4
- 230000008499 blood brain barrier function Effects 0.000 claims 3
- 210000001218 blood-brain barrier Anatomy 0.000 claims 3
- 208000005017 glioblastoma Diseases 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- DWAFYCQODLXJNR-BNTLRKBRSA-L oxaliplatin Chemical compound O1C(=O)C(=O)O[Pt]11N[C@@H]2CCCC[C@H]2N1 DWAFYCQODLXJNR-BNTLRKBRSA-L 0.000 claims 3
- 229960001756 oxaliplatin Drugs 0.000 claims 3
- 239000007787 solid Substances 0.000 claims 3
- 206010006187 Breast cancer Diseases 0.000 claims 2
- 208000026310 Breast neoplasm Diseases 0.000 claims 2
- 208000001333 Colorectal Neoplasms Diseases 0.000 claims 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 2
- 206010050017 Lung cancer metastatic Diseases 0.000 claims 2
- 206010027406 Mesothelioma Diseases 0.000 claims 2
- 206010027476 Metastases Diseases 0.000 claims 2
- 206010033128 Ovarian cancer Diseases 0.000 claims 2
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 2
- 229930012538 Paclitaxel Natural products 0.000 claims 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 2
- 208000005718 Stomach Neoplasms Diseases 0.000 claims 2
- 208000003721 Triple Negative Breast Neoplasms Diseases 0.000 claims 2
- 210000004556 brain Anatomy 0.000 claims 2
- 208000029742 colonic neoplasm Diseases 0.000 claims 2
- 238000009472 formulation Methods 0.000 claims 2
- 206010017758 gastric cancer Diseases 0.000 claims 2
- 201000010536 head and neck cancer Diseases 0.000 claims 2
- 208000014829 head and neck neoplasm Diseases 0.000 claims 2
- 238000002664 inhalation therapy Methods 0.000 claims 2
- 230000009401 metastasis Effects 0.000 claims 2
- 230000001394 metastastic effect Effects 0.000 claims 2
- 206010061289 metastatic neoplasm Diseases 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 230000000683 nonmetastatic effect Effects 0.000 claims 2
- 229960001592 paclitaxel Drugs 0.000 claims 2
- 230000035515 penetration Effects 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 230000005855 radiation Effects 0.000 claims 2
- 238000001959 radiotherapy Methods 0.000 claims 2
- 238000002271 resection Methods 0.000 claims 2
- 239000011780 sodium chloride Substances 0.000 claims 2
- 201000011549 stomach cancer Diseases 0.000 claims 2
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 claims 2
- 208000022679 triple-negative breast carcinoma Diseases 0.000 claims 2
- KSPDSMOWMQFPBL-UHFFFAOYSA-N 5-fluoropyrimidine Chemical compound FC1=CN=CN=C1 KSPDSMOWMQFPBL-UHFFFAOYSA-N 0.000 claims 1
- 239000012624 DNA alkylating agent Substances 0.000 claims 1
- 206010061818 Disease progression Diseases 0.000 claims 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 1
- 208000015634 Rectal Neoplasms Diseases 0.000 claims 1
- 229940123237 Taxane Drugs 0.000 claims 1
- BPEGJWRSRHCHSN-UHFFFAOYSA-N Temozolomide Chemical compound O=C1N(C)N=NC2=C(C(N)=O)N=CN21 BPEGJWRSRHCHSN-UHFFFAOYSA-N 0.000 claims 1
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 229940127089 cytotoxic agent Drugs 0.000 claims 1
- 230000005750 disease progression Effects 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 238000009093 first-line therapy Methods 0.000 claims 1
- SDUQYLNIPVEERB-QPPQHZFASA-N gemcitabine Chemical compound O=C1N=C(N)C=CN1[C@H]1C(F)(F)[C@H](O)[C@@H](CO)O1 SDUQYLNIPVEERB-QPPQHZFASA-N 0.000 claims 1
- 229960005277 gemcitabine Drugs 0.000 claims 1
- 238000009115 maintenance therapy Methods 0.000 claims 1
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 1
- 210000000496 pancreas Anatomy 0.000 claims 1
- 201000002528 pancreatic cancer Diseases 0.000 claims 1
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 1
- 206010038038 rectal cancer Diseases 0.000 claims 1
- 210000000664 rectum Anatomy 0.000 claims 1
- 201000001275 rectum cancer Diseases 0.000 claims 1
- 238000009094 second-line therapy Methods 0.000 claims 1
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 claims 1
- 229960004964 temozolomide Drugs 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
- 238000009095 third-line therapy Methods 0.000 claims 1
- 229960002066 vinorelbine Drugs 0.000 claims 1
- GBABOYUKABKIAF-GHYRFKGUSA-N vinorelbine Chemical compound C1N(CC=2C3=CC=CC=C3NC=22)CC(CC)=C[C@H]1C[C@]2(C(=O)OC)C1=CC([C@]23[C@H]([C@]([C@H](OC(C)=O)[C@]4(CC)C=CCN([C@H]34)CC2)(O)C(=O)OC)N2C)=C2C=C1OC GBABOYUKABKIAF-GHYRFKGUSA-N 0.000 claims 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2012/050626 WO2014027994A1 (en) | 2012-08-13 | 2012-08-13 | Methods for treatment of cancer using lipoplatin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015524467A JP2015524467A (ja) | 2015-08-24 |
| JP2015524467A5 true JP2015524467A5 (enExample) | 2015-10-01 |
Family
ID=50101359
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015526508A Pending JP2015524467A (ja) | 2012-08-13 | 2012-08-13 | Ｌｉｐｏｐｌａｔｉｎを使用するがんの処置方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20150258139A1 (enExample) |
| EP (1) | EP2882419A4 (enExample) |
| JP (1) | JP2015524467A (enExample) |
| KR (1) | KR20150044838A (enExample) |
| CN (1) | CN104271117A (enExample) |
| AU (1) | AU2012387679A1 (enExample) |
| CA (1) | CA2869395A1 (enExample) |
| EA (1) | EA201491629A1 (enExample) |
| IL (1) | IL237229A0 (enExample) |
| MA (1) | MA37930A1 (enExample) |
| SG (1) | SG11201501147WA (enExample) |
| WO (1) | WO2014027994A1 (enExample) |
| ZA (1) | ZA201407159B (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT3393478T (pt) * | 2015-12-23 | 2020-03-24 | NuCana plc | Terapia combinada |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6511676B1 (en) * | 1999-11-05 | 2003-01-28 | Teni Boulikas | Therapy for human cancers using cisplatin and other drugs or genes encapsulated into liposomes |
| GR20060100144A (el) * | 2006-03-03 | 2007-10-17 | Θεραπεια του καρκινου με χρηση οξαλιπλατινης εγκλεισμενης μεσα σε λιποσωματα και απο κοινου εγκλεισμος στο λιποσωμιακο μοριο περισσοτερων απο ενος φαρμακευτικου παρασκευασματος h gene |
-
2012
- 2012-08-13 KR KR20147028694A patent/KR20150044838A/ko not_active Withdrawn
- 2012-08-13 WO PCT/US2012/050626 patent/WO2014027994A1/en not_active Ceased
- 2012-08-13 CN CN201280072456.8A patent/CN104271117A/zh active Pending
- 2012-08-13 EA EA201491629A patent/EA201491629A1/ru unknown
- 2012-08-13 CA CA2869395A patent/CA2869395A1/en not_active Abandoned
- 2012-08-13 AU AU2012387679A patent/AU2012387679A1/en not_active Abandoned
- 2012-08-13 SG SG11201501147WA patent/SG11201501147WA/en unknown
- 2012-08-13 JP JP2015526508A patent/JP2015524467A/ja active Pending
- 2012-08-13 EP EP12882916.5A patent/EP2882419A4/en not_active Withdrawn
- 2012-08-13 US US14/390,352 patent/US20150258139A1/en not_active Abandoned
-
2014
- 2014-10-02 ZA ZA2014/07159A patent/ZA201407159B/en unknown
-
2015
- 2015-02-15 IL IL237229A patent/IL237229A0/en unknown
- 2015-03-12 MA MA37930A patent/MA37930A1/fr unknown
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