JP2015521611A5 - - Google Patents
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- Publication number
- JP2015521611A5 JP2015521611A5 JP2015517753A JP2015517753A JP2015521611A5 JP 2015521611 A5 JP2015521611 A5 JP 2015521611A5 JP 2015517753 A JP2015517753 A JP 2015517753A JP 2015517753 A JP2015517753 A JP 2015517753A JP 2015521611 A5 JP2015521611 A5 JP 2015521611A5
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- peptide according
- seq
- disease
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 108090000765 processed proteins & peptides Proteins 0.000 claims 17
- 102100024616 Platelet endothelial cell adhesion molecule Human genes 0.000 claims 5
- 125000003275 alpha amino acid group Chemical group 0.000 claims 4
- 150000001413 amino acids Chemical class 0.000 claims 4
- 239000007787 solid Substances 0.000 claims 3
- 208000022559 Inflammatory bowel disease Diseases 0.000 claims 2
- 208000007536 Thrombosis Diseases 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 208000027866 inflammatory disease Diseases 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 208000004476 Acute Coronary Syndrome Diseases 0.000 claims 1
- 206010003178 Arterial thrombosis Diseases 0.000 claims 1
- 201000001320 Atherosclerosis Diseases 0.000 claims 1
- 208000023328 Basedow disease Diseases 0.000 claims 1
- 241000283690 Bos taurus Species 0.000 claims 1
- 208000005145 Cerebral amyloid angiopathy Diseases 0.000 claims 1
- 206010012438 Dermatitis atopic Diseases 0.000 claims 1
- 208000015023 Graves' disease Diseases 0.000 claims 1
- 208000032382 Ischaemic stroke Diseases 0.000 claims 1
- 208000005764 Peripheral Arterial Disease Diseases 0.000 claims 1
- 208000030831 Peripheral arterial occlusive disease Diseases 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 claims 1
- 210000001744 T-lymphocyte Anatomy 0.000 claims 1
- 206010047115 Vasculitis Diseases 0.000 claims 1
- 208000002223 abdominal aortic aneurysm Diseases 0.000 claims 1
- 230000004913 activation Effects 0.000 claims 1
- 208000007474 aortic aneurysm Diseases 0.000 claims 1
- 230000007214 atherothrombosis Effects 0.000 claims 1
- 201000008937 atopic dermatitis Diseases 0.000 claims 1
- 206010012601 diabetes mellitus Diseases 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 230000001404 mediated effect Effects 0.000 claims 1
- 201000006417 multiple sclerosis Diseases 0.000 claims 1
- 210000005259 peripheral blood Anatomy 0.000 claims 1
- 239000011886 peripheral blood Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 230000036470 plasma concentration Effects 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 1
- 230000011664 signaling Effects 0.000 claims 1
- 238000007920 subcutaneous administration Methods 0.000 claims 1
- 239000013589 supplement Substances 0.000 claims 1
- 201000000596 systemic lupus erythematosus Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12305697 | 2012-06-19 | ||
| EP12305697.0 | 2012-06-19 | ||
| PCT/EP2013/062806 WO2013190014A1 (en) | 2012-06-19 | 2013-06-19 | Improved cd31 peptides |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015521611A JP2015521611A (ja) | 2015-07-30 |
| JP2015521611A5 true JP2015521611A5 (enExample) | 2016-07-07 |
| JP6357470B2 JP6357470B2 (ja) | 2018-07-11 |
Family
ID=48652100
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015517753A Active JP6357470B2 (ja) | 2012-06-19 | 2013-06-19 | 改良されたｃｄ３１ペプチド |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US10815272B2 (enExample) |
| EP (1) | EP2861241B1 (enExample) |
| JP (1) | JP6357470B2 (enExample) |
| DK (1) | DK2861241T3 (enExample) |
| ES (1) | ES2877513T3 (enExample) |
| HR (1) | HRP20211017T1 (enExample) |
| HU (1) | HUE055593T2 (enExample) |
| PL (1) | PL2861241T3 (enExample) |
| PT (1) | PT2861241T (enExample) |
| SI (1) | SI2861241T1 (enExample) |
| WO (1) | WO2013190014A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109069586A (zh) * | 2016-03-21 | 2018-12-21 | 国家健康与医学研究院 | 用于再灌注损伤的预防和/或治疗的cd31shed激动剂 |
| JP7166512B2 (ja) * | 2016-05-03 | 2022-11-08 | インスティチュート ナショナル デ ラ サンテ エ デ ラ ルシェルシュ メディカル （インセルム） | 炎症のイメージングのための分子標識としてのＣＤ３１ｓｈｅｄ |
| US20220001083A1 (en) * | 2018-11-27 | 2022-01-06 | Balt Extrusion | Method for the modification of a device surface by grafting a cd31-derived peptide onto the surface of said device |
| WO2020109833A1 (en) | 2018-11-27 | 2020-06-04 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Method for the modification of a substrate surface by grafting a peptide onto the surface of said substrate |
| WO2023099932A1 (en) * | 2021-12-03 | 2023-06-08 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Cd31 mimetic coating for endovascular stent |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6087331A (en) | 1990-01-19 | 2000-07-11 | The Blood Center Of Southeastern Wisconsin | Therapeutic use of platelet-endothelial cell adhesion molecule-1 compositions |
| JP3914988B2 (ja) * | 2003-08-06 | 2007-05-16 | 国立大学法人名古屋大学 | 細胞死誘導のためのペプチドおよび医薬 |
| EP2313432B1 (en) * | 2008-06-30 | 2017-09-13 | Institut National de la Sante et de la Recherche Medicale (INSERM) | Use of cd31 peptides in the treatment of thrombotic and autoimmune disorders |
| WO2013152919A1 (en) | 2012-04-11 | 2013-10-17 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Detection of platelet-derived shed cd31 |
-
2013
- 2013-06-19 WO PCT/EP2013/062806 patent/WO2013190014A1/en not_active Ceased
- 2013-06-19 HU HUE13729753A patent/HUE055593T2/hu unknown
- 2013-06-19 PL PL13729753T patent/PL2861241T3/pl unknown
- 2013-06-19 PT PT137297537T patent/PT2861241T/pt unknown
- 2013-06-19 ES ES13729753T patent/ES2877513T3/es active Active
- 2013-06-19 JP JP2015517753A patent/JP6357470B2/ja active Active
- 2013-06-19 HR HRP20211017TT patent/HRP20211017T1/hr unknown
- 2013-06-19 DK DK13729753.7T patent/DK2861241T3/da active
- 2013-06-19 EP EP13729753.7A patent/EP2861241B1/en active Active
- 2013-06-19 US US14/408,789 patent/US10815272B2/en active Active
- 2013-06-19 SI SI201331896T patent/SI2861241T1/sl unknown
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