JP2015521041A5 - - Google Patents
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- Publication number
- JP2015521041A5 JP2015521041A5 JP2015511948A JP2015511948A JP2015521041A5 JP 2015521041 A5 JP2015521041 A5 JP 2015521041A5 JP 2015511948 A JP2015511948 A JP 2015511948A JP 2015511948 A JP2015511948 A JP 2015511948A JP 2015521041 A5 JP2015521041 A5 JP 2015521041A5
- Authority
- JP
- Japan
- Prior art keywords
- pkn3
- inhibitor
- vegfr1
- suffering
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 101000691455 Homo sapiens Serine/threonine-protein kinase N3 Proteins 0.000 claims 2
- 101000851018 Homo sapiens Vascular endothelial growth factor receptor 1 Proteins 0.000 claims 2
- 102100026219 Serine/threonine-protein kinase N3 Human genes 0.000 claims 2
- 102100033178 Vascular endothelial growth factor receptor 1 Human genes 0.000 claims 2
- 239000003112 inhibitor Substances 0.000 claims 2
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12003888 | 2012-05-16 | ||
| EP12003888.0 | 2012-05-16 | ||
| PCT/EP2013/001441 WO2013170960A1 (en) | 2012-05-16 | 2013-05-15 | Use of vegfr1 as a biomarker for pkn3 inhibitor administration |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015521041A JP2015521041A (ja) | 2015-07-27 |
| JP2015521041A5 true JP2015521041A5 (enExample) | 2016-07-07 |
Family
ID=48446240
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015511948A Pending JP2015521041A (ja) | 2012-05-16 | 2013-05-15 | Ｐｋｎ３阻害剤投与のためのバイオマーカーとしてのｖｅｇｆｒ１の使用 |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US9133515B2 (enExample) |
| EP (1) | EP2849771A1 (enExample) |
| JP (1) | JP2015521041A (enExample) |
| WO (1) | WO2013170960A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016083623A1 (en) * | 2014-11-28 | 2016-06-02 | Silence Therapeutics Gmbh | Means for the treatment of pre-eclampsia |
| CN110177544A (zh) | 2016-11-29 | 2019-08-27 | 普尔泰克健康有限公司 | 用于递送治疗剂的外泌体 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0533838B1 (en) | 1990-06-11 | 1997-12-03 | NeXstar Pharmaceuticals, Inc. | Nucleic acid ligands |
| US20040220128A1 (en) * | 1995-10-26 | 2004-11-04 | Sirna Therapeutics, Inc. | Nucleic acid based modulation of female reproductive diseases and conditions |
| DE59708838D1 (de) | 1996-08-30 | 2003-01-09 | Jens Peter Fuerste | Spiegelselektion und spiegelevolution von nucleinsäuren |
| US5849902A (en) | 1996-09-26 | 1998-12-15 | Oligos Etc. Inc. | Three component chimeric antisense oligonucleotides |
| US6958239B2 (en) | 1996-11-21 | 2005-10-25 | Oligos Etc Inc. | Three component chimeric antisense oligonucleotides |
| DE19742706B4 (de) | 1997-09-26 | 2013-07-25 | Pieris Proteolab Ag | Lipocalinmuteine |
| DE19956568A1 (de) | 1999-01-30 | 2000-08-17 | Roland Kreutzer | Verfahren und Medikament zur Hemmung der Expression eines vorgegebenen Gens |
| KR101215789B1 (ko) | 2000-03-30 | 2012-12-26 | 화이트헤드 인스티튜트 포 바이오메디칼 리서치 | Ｒｎａ 간섭의 ｒｎａ 서열 특이적인 매개체 |
| IL166718A0 (en) | 2002-08-14 | 2006-01-15 | Atugen Ag | Further use of protein kinase n beta |
| KR101670085B1 (ko) | 2006-07-21 | 2016-10-28 | 사일런스 테라퓨틱스 게엠베하 | 단백질 키나아제 3의 발현을 억제하기 위한 수단 |
-
2013
- 2013-05-15 US US13/894,650 patent/US9133515B2/en not_active Expired - Fee Related
- 2013-05-15 JP JP2015511948A patent/JP2015521041A/ja active Pending
- 2013-05-15 WO PCT/EP2013/001441 patent/WO2013170960A1/en not_active Ceased
- 2013-05-15 EP EP13723000.9A patent/EP2849771A1/en not_active Withdrawn
-
2015
- 2015-08-28 US US14/838,431 patent/US20150368650A1/en not_active Abandoned
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