JP2015520383A - 変形性関節症を診断するための方法 - Google Patents

変形性関節症を診断するための方法 Download PDF

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Publication number
JP2015520383A
JP2015520383A JP2015516117A JP2015516117A JP2015520383A JP 2015520383 A JP2015520383 A JP 2015520383A JP 2015516117 A JP2015516117 A JP 2015516117A JP 2015516117 A JP2015516117 A JP 2015516117A JP 2015520383 A JP2015520383 A JP 2015520383A
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Japan
Prior art keywords
cytokine
subject
concentration
osteoarthritis
pdgf
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Pending
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JP2015516117A
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English (en)
Japanese (ja)
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JP2015520383A5 (enExample
Inventor
クリスタ、オショーネシー
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Biomet Biologics LLC
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Biomet Biologics LLC
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Application filed by Biomet Biologics LLC filed Critical Biomet Biologics LLC
Publication of JP2015520383A publication Critical patent/JP2015520383A/ja
Publication of JP2015520383A5 publication Critical patent/JP2015520383A5/ja
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors
    • G01N2333/485—Epidermal growth factor [EGF] (urogastrone)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors
    • G01N2333/49—Platelet-derived growth factor [PDGF]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders
    • G01N2800/105—Osteoarthritis, e.g. cartilage alteration, hypertrophy of bone
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2015516117A 2012-06-04 2013-06-04 変形性関節症を診断するための方法 Pending JP2015520383A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261655322P 2012-06-04 2012-06-04
US61/655,322 2012-06-04
PCT/US2013/044075 WO2013184660A1 (en) 2012-06-04 2013-06-04 Methods for diagnosing osteoarthritis

Publications (2)

Publication Number Publication Date
JP2015520383A true JP2015520383A (ja) 2015-07-16
JP2015520383A5 JP2015520383A5 (enExample) 2016-07-28

Family

ID=48626668

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015516117A Pending JP2015520383A (ja) 2012-06-04 2013-06-04 変形性関節症を診断するための方法

Country Status (5)

Country Link
US (1) US20150141332A1 (enExample)
EP (1) EP2856171A1 (enExample)
JP (1) JP2015520383A (enExample)
CN (1) CN104471406A (enExample)
WO (1) WO2013184660A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2567692B1 (en) 2008-02-27 2016-04-06 Biomet Biologics, LLC Use of a device for obtaining interleukin-1 receptor antagonist rich solutions
US9895418B2 (en) 2013-03-15 2018-02-20 Biomet Biologics, Llc Treatment of peripheral vascular disease using protein solutions
US10208095B2 (en) 2013-03-15 2019-02-19 Biomet Manufacturing, Llc Methods for making cytokine compositions from tissues using non-centrifugal methods
US20140271589A1 (en) 2013-03-15 2014-09-18 Biomet Biologics, Llc Treatment of collagen defects using protein solutions
US10143725B2 (en) 2013-03-15 2018-12-04 Biomet Biologics, Llc Treatment of pain using protein solutions
US9878011B2 (en) 2013-03-15 2018-01-30 Biomet Biologics, Llc Treatment of inflammatory respiratory disease using biological solutions
US9758806B2 (en) 2013-03-15 2017-09-12 Biomet Biologics, Llc Acellular compositions for treating inflammatory disorders
US9950035B2 (en) 2013-03-15 2018-04-24 Biomet Biologics, Llc Methods and non-immunogenic compositions for treating inflammatory disorders
US9833474B2 (en) 2013-11-26 2017-12-05 Biomet Biologies, LLC Methods of mediating macrophage phenotypes
US10441635B2 (en) 2014-11-10 2019-10-15 Biomet Biologics, Llc Methods of treating pain using protein solutions
CN111855999A (zh) * 2020-06-02 2020-10-30 广东省药品检验所（广东省药品质量研究所、广东省口岸药品检验所） 一种化妆品中rhEGF快速检测试纸卡、试剂盒及其检测方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001057900A (ja) * 1999-08-24 2001-03-06 Seikagaku Kogyo Co Ltd 関節疾患検出法
JP2007506100A (ja) * 2003-09-15 2007-03-15 オクラホマ　メディカル　リサーチ　ファウンデーション 炎症性疾患および自己免疫疾患を診断、治療および評価するためにサイトカインアッセイを用いる方法
JP2008510168A (ja) * 2004-08-18 2008-04-03 アメリカ合衆国 骨関節炎のバイオマーカー
US20110306512A1 (en) * 2008-06-25 2011-12-15 Dxterity Diagnostics Gene Expression Profiling for Identification, Monitoring, and Treatment of Osteoarthritis

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120030593A1 (en) 1995-11-13 2012-02-02 Lakshmi Arunachalam Method and apparatus for enabling real-time bi-directional transactions on a network
CN1977049A (zh) * 2004-04-26 2007-06-06 儿童医疗中心有限公司 用于检测疾病的血小板生物标志物
EP2567692B1 (en) 2008-02-27 2016-04-06 Biomet Biologics, LLC Use of a device for obtaining interleukin-1 receptor antagonist rich solutions
US8753690B2 (en) 2008-02-27 2014-06-17 Biomet Biologics, Llc Methods and compositions for delivering interleukin-1 receptor antagonist
US20110052561A1 (en) 2009-08-27 2011-03-03 Biomet Biologics,LLC Osteolysis treatment
WO2011031553A2 (en) 2009-08-27 2011-03-17 Biomet Biologics, Llc Implantable device for production of interleukin-1 receptor antagonist

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001057900A (ja) * 1999-08-24 2001-03-06 Seikagaku Kogyo Co Ltd 関節疾患検出法
JP2007506100A (ja) * 2003-09-15 2007-03-15 オクラホマ　メディカル　リサーチ　ファウンデーション 炎症性疾患および自己免疫疾患を診断、治療および評価するためにサイトカインアッセイを用いる方法
JP2008510168A (ja) * 2004-08-18 2008-04-03 アメリカ合衆国 骨関節炎のバイオマーカー
US20110306512A1 (en) * 2008-06-25 2011-12-15 Dxterity Diagnostics Gene Expression Profiling for Identification, Monitoring, and Treatment of Osteoarthritis

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
EDUARDO ANITUA ET AL.: "Relationship between Investigative Biomakers and Radiographic Grading in Patients with Knee Ostoarth", INTERNATIONAL JOURNAL OF RHEUMATOLOGY, JPN6017015409, 2009, pages 747432, ISSN: 0003548184 *
JENNIFER WOODELL-MAY ET AL.: "Autologous Protein Solution Inhibits MMP-13 Production by IL-1b and TNFa-Stimulated Human Articular", JOURNAL OF ORHOPAEDIC RESEACH, vol. 20, JPN6017015408, 2011, pages 1320 - 1326, ISSN: 0003548183 *

Also Published As

Publication number Publication date
EP2856171A1 (en) 2015-04-08
US20150141332A1 (en) 2015-05-21
CN104471406A (zh) 2015-03-25
WO2013184660A1 (en) 2013-12-12

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