JP2015516451A5 - - Google Patents
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- Publication number
- JP2015516451A5 JP2015516451A5 JP2015511957A JP2015511957A JP2015516451A5 JP 2015516451 A5 JP2015516451 A5 JP 2015516451A5 JP 2015511957 A JP2015511957 A JP 2015511957A JP 2015511957 A JP2015511957 A JP 2015511957A JP 2015516451 A5 JP2015516451 A5 JP 2015516451A5
- Authority
- JP
- Japan
- Prior art keywords
- pain
- pharmaceutical dosage
- weeks
- hours
- refers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 208000002193 Pain Diseases 0.000 description 6
- 239000002552 dosage form Substances 0.000 description 5
- 208000005298 acute pain Diseases 0.000 description 2
- 239000002831 pharmacologic agent Substances 0.000 description 2
- 208000000094 Chronic Pain Diseases 0.000 description 1
- 238000013270 controlled release Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12003895.5 | 2012-05-18 | ||
| EP12003895 | 2012-05-18 | ||
| PCT/EP2013/001470 WO2013170971A1 (en) | 2012-05-18 | 2013-05-16 | Pharmaceutical composition comprising (1r,4r)-6'-fluoro-n,n-dimethyl-4-phenyl-4',9'-dihydro-3'h-spiro[cyclohexane-1,1'-pyrano [3,4,b]indol]-4-amine and a nsar |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015516451A JP2015516451A (ja) | 2015-06-11 |
| JP2015516451A5 true JP2015516451A5 (OSRAM) | 2017-03-09 |
| JP6116678B2 JP6116678B2 (ja) | 2017-04-19 |
Family
ID=48520892
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015511957A Active JP6116678B2 (ja) | 2012-05-18 | 2013-05-16 | （１ｒ，４ｒ）−６’−フルオロ−Ｎ，Ｎ−ジメチル−４−フェニル−４’，９’−ジヒドロ−３’Ｈ−スピロ［シクロヘキサン−１，１’−ピラノ［３，４，ｂ］インドール］−４−アミンおよびＮＳＡＲを含む医薬組成物 |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US8912226B2 (OSRAM) |
| EP (1) | EP2849747B1 (OSRAM) |
| JP (1) | JP6116678B2 (OSRAM) |
| CN (1) | CN104284660A (OSRAM) |
| AU (1) | AU2013262077B2 (OSRAM) |
| BR (1) | BR112014028566A2 (OSRAM) |
| CA (1) | CA2873867A1 (OSRAM) |
| CY (1) | CY1119781T1 (OSRAM) |
| DK (1) | DK2849747T3 (OSRAM) |
| EA (1) | EA027145B1 (OSRAM) |
| ES (1) | ES2658217T3 (OSRAM) |
| HR (1) | HRP20171725T1 (OSRAM) |
| HU (1) | HUE034658T2 (OSRAM) |
| IL (1) | IL235653B (OSRAM) |
| LT (1) | LT2849747T (OSRAM) |
| MX (1) | MX356493B (OSRAM) |
| NO (1) | NO2849747T3 (OSRAM) |
| PL (1) | PL2849747T3 (OSRAM) |
| PT (1) | PT2849747T (OSRAM) |
| RS (1) | RS56788B1 (OSRAM) |
| SI (1) | SI2849747T1 (OSRAM) |
| WO (1) | WO2013170971A1 (OSRAM) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10022353B2 (en) | 2015-01-23 | 2018-07-17 | Grünenthal GmbH | Cebranopadol for treating pain in subjects with impaired hepatic and/or impaired renal function |
| WO2016168388A2 (en) | 2015-04-14 | 2016-10-20 | Palatin Technologies, Inc. | Therapies for obesity, diabetes and related indications |
| JP7373904B2 (ja) | 2016-02-29 | 2023-11-06 | パーク・セラピューティクス・インコーポレイテッド | セブラノパドールの滴定 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0068838B1 (en) | 1981-06-26 | 1986-09-17 | The Upjohn Company | Analgesic process and composition |
| US4389393A (en) | 1982-03-26 | 1983-06-21 | Forest Laboratories, Inc. | Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose |
| US4404208A (en) * | 1982-06-30 | 1983-09-13 | E. I. Du Pont De Nemours And Company | Analgesic mixture of nalbuphine and tiflamizole |
| US4612008A (en) | 1983-05-11 | 1986-09-16 | Alza Corporation | Osmotic device with dual thermodynamic activity |
| US4765989A (en) | 1983-05-11 | 1988-08-23 | Alza Corporation | Osmotic device for administering certain drugs |
| US4783337A (en) | 1983-05-11 | 1988-11-08 | Alza Corporation | Osmotic system comprising plurality of members for dispensing drug |
| EP0473655B1 (en) | 1989-05-22 | 1997-01-15 | Biochemical Veterinary Research Pty. Ltd. | Divalent metal salts of indomethacin |
| US5472711A (en) | 1992-07-30 | 1995-12-05 | Edward Mendell Co., Inc. | Agglomerated hydrophilic complexes with multi-phasic release characteristics |
| US5330761A (en) | 1993-01-29 | 1994-07-19 | Edward Mendell Co. Inc. | Bioadhesive tablet for non-systemic use products |
| US5455046A (en) | 1993-09-09 | 1995-10-03 | Edward Mendell Co., Inc. | Sustained release heterodisperse hydrogel systems for insoluble drugs |
| US5399362A (en) | 1994-04-25 | 1995-03-21 | Edward Mendell Co., Inc. | Once-a-day metoprolol oral dosage form |
| US5914129A (en) | 1996-07-23 | 1999-06-22 | Mauskop; Alexander | Analgesic composition for treatment of migraine headaches |
| DE50104197D1 (de) | 2000-12-28 | 2004-11-25 | Fresenius Kabi Austria Gmbh Gr | Stabile Infusionslösung von Diclofenac-Salzen, deren Herstellung und Verwendung |
| DE60219609T2 (de) | 2002-06-17 | 2008-01-03 | Chiesi Farmaceutici S.P.A. | Prozess für die Vorbereitung von Piroxicam: Beta-Cyclodextrin Einschlusskomplexe |
| DE10252667A1 (de) * | 2002-11-11 | 2004-05-27 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
| DE10257824B4 (de) | 2002-12-10 | 2004-11-11 | Kochem, Hans-Günter, Dr. | Zusammensetzung zur Schmerzbehandlung, insbesondere zur Behandlung von Gelenkschmerzen |
| US20100297252A1 (en) | 2003-03-03 | 2010-11-25 | Elan Pharma International Ltd. | Nanoparticulate meloxicam formulations |
| US7132452B2 (en) | 2003-03-10 | 2006-11-07 | Fang-Yu Lee | Topical formulation having effects on alleviating pain/inflammation caused by herpes virus infection |
| DE10360792A1 (de) | 2003-12-23 | 2005-07-28 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
| CN101198606A (zh) * | 2005-06-17 | 2008-06-11 | 辉瑞有限公司 | 作为ORL1-受体拮抗剂的α-(芳基-或杂芳基-甲基-)-β哌啶子基丙酰胺化合物 |
| PT2012763E (pt) * | 2006-04-28 | 2011-04-29 | Gruenenthal Gmbh | Combinação farmacêutica que compreende 3-(3-dimetilamino-1-etil-2-metil-propil)fenol e um aine |
| CN101147735A (zh) | 2006-09-19 | 2008-03-26 | 沈阳华泰药物研究有限公司 | 注射用药物组合物及其药盒 |
| DE102006046745A1 (de) | 2006-09-29 | 2008-04-03 | Grünenthal GmbH | Gemischte ORL1/µ-Agonisten zur Behandlung von Schmerz |
| DE102006056458A1 (de) | 2006-11-28 | 2008-05-29 | Grünenthal GmbH | Arzneimittelzubereitung von Tramadol und Acetaminophen |
| CA2701838A1 (en) * | 2007-10-09 | 2009-04-16 | Merck Patent Gmbh | Pharmaceutical compositions containing benfotiamine and one or more pharmaceutically active agents for the treatment of pain conditions of neuropathic origin |
| CN100560061C (zh) | 2008-06-20 | 2009-11-18 | 海南锦瑞制药股份有限公司 | 一种氯诺昔康冻干粉针剂及其制备方法 |
| KR101851120B1 (ko) * | 2008-09-05 | 2018-04-23 | 그뤼넨탈 게엠베하 | 3-（3-디메틸아미노-1-에틸-2-메틸-프로필）-페놀과 항간질제의 약제학적 병용물 |
| AR073495A1 (es) * | 2008-09-05 | 2010-11-10 | Gruenenthal Gmbh | Combinacion farmaceutica que contiene el 6-dimetilaminometil-1- (3-metoxi-fenil)-ciclohexano-1,3-diol y un nsaid |
| EP2600846B1 (en) * | 2010-08-04 | 2015-11-25 | Grünenthal GmbH | Pharmaceutical dosage form comprising 6'-fluoro-(n-methyl- or n,n-dimethyl-)-4-phenyl-4',9'-dihydro-3'h-spiro[cylohexane-1,1'-pyrano[3,4,b]indol]-4-amine |
| MX2013000980A (es) * | 2010-08-04 | 2013-02-15 | Gruenenthal Gmbh | Forma de dosificacion farmaceutica que comprende 6'-fluoro-(n-metil- o n, n-dimetil-)-4-fenil-4', 9'-dihidro-3'h-espiro [ciclohexan-1, 1'-pirano[3, 4, b]indol]-4-amina. |
| AU2011287955B2 (en) * | 2010-08-04 | 2015-07-09 | Grünenthal GmbH | Pharmaceutical dosage form comprising 6'-fluoro-(N-methyl- or N,N-dimethyl-)-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine for the treatment of neuropathic pain |
-
2013
- 2013-05-13 US US13/892,732 patent/US8912226B2/en active Active
- 2013-05-16 AU AU2013262077A patent/AU2013262077B2/en not_active Ceased
- 2013-05-16 EA EA201401270A patent/EA027145B1/ru not_active IP Right Cessation
- 2013-05-16 WO PCT/EP2013/001470 patent/WO2013170971A1/en not_active Ceased
- 2013-05-16 CA CA2873867A patent/CA2873867A1/en not_active Abandoned
- 2013-05-16 DK DK13725072.6T patent/DK2849747T3/en active
- 2013-05-16 HR HRP20171725TT patent/HRP20171725T1/hr unknown
- 2013-05-16 CN CN201380025645.4A patent/CN104284660A/zh active Pending
- 2013-05-16 PL PL13725072T patent/PL2849747T3/pl unknown
- 2013-05-16 NO NO13725072A patent/NO2849747T3/no unknown
- 2013-05-16 RS RS20180063A patent/RS56788B1/sr unknown
- 2013-05-16 JP JP2015511957A patent/JP6116678B2/ja active Active
- 2013-05-16 SI SI201330926T patent/SI2849747T1/en unknown
- 2013-05-16 EP EP13725072.6A patent/EP2849747B1/en not_active Not-in-force
- 2013-05-16 MX MX2014013028A patent/MX356493B/es active IP Right Grant
- 2013-05-16 LT LTEP13725072.6T patent/LT2849747T/lt unknown
- 2013-05-16 ES ES13725072.6T patent/ES2658217T3/es active Active
- 2013-05-16 HU HUE13725072A patent/HUE034658T2/hu unknown
- 2013-05-16 PT PT137250726T patent/PT2849747T/pt unknown
- 2013-05-16 BR BR112014028566A patent/BR112014028566A2/pt active Search and Examination
-
2014
- 2014-11-12 IL IL235653A patent/IL235653B/en active IP Right Grant
-
2018
- 2018-01-16 CY CY20181100051T patent/CY1119781T1/el unknown
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