JP2015515855A5 - - Google Patents

Info

Publication number

JP2015515855A5

JP2015515855A5 JP2015503152A JP2015503152A JP2015515855A5 JP 2015515855 A5 JP2015515855 A5 JP 2015515855A5 JP 2015503152 A JP2015503152 A JP 2015503152A JP 2015503152 A JP2015503152 A JP 2015503152A JP 2015515855 A5 JP2015515855 A5 JP 2015515855A5

Authority

JP

Japan

Prior art keywords

pro

lys

thr

gly

phe

Prior art date

2013-05-28

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
• Discuss

• 125000003630 glycyl group Chemical group [H]N([H])C([H])([H])C(*)=O 0.000 claims 10
• 239000008194 pharmaceutical composition Substances 0.000 claims 9
• COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 claims 8
• 125000000174 L-prolyl group Chemical group [H]N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(*)=O 0.000 claims 5
• 230000001850 reproductive Effects 0.000 claims 5
• DCXYFEDJOCDNAF-REOHCLBHSA-N L-asparagine Chemical compound OC(=O)[C@@H](N)CC(N)=O DCXYFEDJOCDNAF-REOHCLBHSA-N 0.000 claims 4
• ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 claims 4
• KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 claims 4
• OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 claims 4
• 125000000998 L-alanino group Chemical group [H]N([*])[C@](C([H])([H])[H])([H])C(=O)O[H] 0.000 claims 3
• 125000000510 L-tryptophano group Chemical group [H]C1=C([H])C([H])=C2N([H])C([H])=C(C([H])([H])[C@@]([H])(C(O[H])=O)N([H])[*])C2=C1[H] 0.000 claims 3
• 241000124008 Mammalia Species 0.000 claims 3
• 125000002041 N(2)-L-arginino group Chemical group [H]OC(=O)[C@@]([H])(N([H])[*])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H] 0.000 claims 3
• 239000003814 drug Substances 0.000 claims 3
• 201000001880 sexual dysfunction Diseases 0.000 claims 3
• 231100000872 sexual dysfunction Toxicity 0.000 claims 3
• ODKSFYDXXFIFQN-BYPYZUCNSA-N L-arginine Chemical compound OC(=O)[C@@H](N)CCCN=C(N)N ODKSFYDXXFIFQN-BYPYZUCNSA-N 0.000 claims 2
• KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 claims 2
• 238000004519 manufacturing process Methods 0.000 claims 2
• 230000001568 sexual Effects 0.000 claims 2
• 230000001225 therapeutic Effects 0.000 claims 2
• CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 claims 1
• 125000000539 amino acid group Chemical group 0.000 claims 1
• 244000005700 microbiome Species 0.000 claims 1
• 239000000203 mixture Substances 0.000 claims 1
• 102000004196 processed proteins & peptides Human genes 0.000 claims 1
• 108090000765 processed proteins & peptides Proteins 0.000 claims 1
• 150000003839 salts Chemical class 0.000 claims 1
• 239000011780 sodium chloride Substances 0.000 claims 1
• 230000004936 stimulating Effects 0.000 claims 1
• 230000000638 stimulation Effects 0.000 claims 1
• 238000003786 synthesis reaction Methods 0.000 claims 1