JP2015514703A - ピリミドジアゼピノンを用いた増殖性疾患の治療 - Google Patents

ピリミドジアゼピノンを用いた増殖性疾患の治療 Download PDF

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Publication number
JP2015514703A
JP2015514703A JP2015502453A JP2015502453A JP2015514703A JP 2015514703 A JP2015514703 A JP 2015514703A JP 2015502453 A JP2015502453 A JP 2015502453A JP 2015502453 A JP2015502453 A JP 2015502453A JP 2015514703 A JP2015514703 A JP 2015514703A
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hours
compound
period
plasma concentration
administered
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JP2015502453A
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Japanese (ja)
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JP2015514703A5 (cg-RX-API-DMAC10.html
Inventor
スーザン デイヴィス
スーザン デイヴィス
ダニエラ ゼレヴァ
ダニエラ ゼレヴァ
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サイクラセル リミテッド
サイクラセル リミテッド
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Publication of JP2015514703A publication Critical patent/JP2015514703A/ja
Publication of JP2015514703A5 publication Critical patent/JP2015514703A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2015502453A 2012-03-30 2013-03-28 ピリミドジアゼピノンを用いた増殖性疾患の治療 Pending JP2015514703A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1205752.7 2012-03-30
GB201205752A GB201205752D0 (en) 2012-03-30 2012-03-30 Treatment
PCT/GB2013/050816 WO2013144632A1 (en) 2012-03-30 2013-03-28 Treatment of proliferative diseases with pyrimidodiazepinones

Publications (2)

Publication Number Publication Date
JP2015514703A true JP2015514703A (ja) 2015-05-21
JP2015514703A5 JP2015514703A5 (cg-RX-API-DMAC10.html) 2016-05-26

Family

ID=46160090

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015502453A Pending JP2015514703A (ja) 2012-03-30 2013-03-28 ピリミドジアゼピノンを用いた増殖性疾患の治療

Country Status (5)

Country Link
US (1) US20150320762A1 (cg-RX-API-DMAC10.html)
EP (1) EP2833865A1 (cg-RX-API-DMAC10.html)
JP (1) JP2015514703A (cg-RX-API-DMAC10.html)
GB (1) GB201205752D0 (cg-RX-API-DMAC10.html)
WO (1) WO2013144632A1 (cg-RX-API-DMAC10.html)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016515537A (ja) * 2013-03-15 2016-05-30 ダナ ファーバー キャンサー インスティテュート，インコーポレイテッド ピリミド−ジアゼピノン化合物および障害の治療方法
KR20220047822A (ko) * 2019-08-16 2022-04-19 싸이클라셀 리미티드 피리미디노 디아제핀 유도체의 결정질 형태

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101878216B (zh) 2007-09-28 2013-07-10 西克拉塞尔有限公司 作为蛋白激酶抑制剂的嘧啶衍生物

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010540509A (ja) * 2007-09-28 2010-12-24 サイクラセル リミテッド プロテインキナーゼ阻害剤としてのピリミジン誘導体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0302220D0 (en) 2003-01-30 2003-03-05 Cyclacel Ltd Use
TW200808325A (en) * 2006-07-06 2008-02-16 Astrazeneca Ab Novel compounds
GB0718608D0 (en) 2007-09-24 2007-10-31 Tyco Electronics Raychem Nv Cable termination

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010540509A (ja) * 2007-09-28 2010-12-24 サイクラセル リミテッド プロテインキナーゼ阻害剤としてのピリミジン誘導体

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016515537A (ja) * 2013-03-15 2016-05-30 ダナ ファーバー キャンサー インスティテュート，インコーポレイテッド ピリミド−ジアゼピノン化合物および障害の治療方法
KR20220047822A (ko) * 2019-08-16 2022-04-19 싸이클라셀 리미티드 피리미디노 디아제핀 유도체의 결정질 형태
KR102974905B1 (ko) 2019-08-16 2026-06-08 싸이클라셀 리미티드 피리미디노 디아제핀 유도체의 결정질 형태

Also Published As

Publication number Publication date
US20150320762A1 (en) 2015-11-12
EP2833865A1 (en) 2015-02-11
GB201205752D0 (en) 2012-05-16
WO2013144632A1 (en) 2013-10-03

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