JP2015513532A5 - - Google Patents
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- Publication number
- JP2015513532A5 JP2015513532A5 JP2014557758A JP2014557758A JP2015513532A5 JP 2015513532 A5 JP2015513532 A5 JP 2015513532A5 JP 2014557758 A JP2014557758 A JP 2014557758A JP 2014557758 A JP2014557758 A JP 2014557758A JP 2015513532 A5 JP2015513532 A5 JP 2015513532A5
- Authority
- JP
- Japan
- Prior art keywords
- lipase
- container
- pufa
- item
- nutritional
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 108090001060 Lipase Proteins 0.000 claims description 113
- 102000004882 Lipase Human genes 0.000 claims description 113
- 239000004367 Lipase Substances 0.000 claims description 113
- 235000019421 lipase Nutrition 0.000 claims description 113
- 235000016709 nutrition Nutrition 0.000 claims description 98
- 239000000203 mixture Substances 0.000 claims description 97
- 238000000034 method Methods 0.000 claims description 74
- 235000020978 long-chain polyunsaturated fatty acids Nutrition 0.000 claims description 69
- 239000007788 liquid Substances 0.000 claims description 45
- 238000009472 formulation Methods 0.000 claims description 42
- 150000002148 esters Chemical class 0.000 claims description 21
- 239000007787 solid Substances 0.000 claims description 20
- 150000003626 triacylglycerols Chemical class 0.000 claims description 17
- 238000002360 preparation method Methods 0.000 claims description 15
- 230000037406 food intake Effects 0.000 claims description 11
- 101001003495 Pseudomonas fluorescens Lipase Proteins 0.000 claims description 10
- 101001064559 Pseudomonas fluorescens Lipase Proteins 0.000 claims description 10
- OGBUMNBNEWYMNJ-UHFFFAOYSA-N batilol Chemical class CCCCCCCCCCCCCCCCCCOCC(O)CO OGBUMNBNEWYMNJ-UHFFFAOYSA-N 0.000 claims description 10
- 235000021588 free fatty acids Nutrition 0.000 claims description 10
- 239000002245 particle Substances 0.000 claims description 8
- 101000966369 Rhizopus oryzae Lipase Proteins 0.000 claims description 7
- 235000013350 formula milk Nutrition 0.000 claims description 7
- 239000000463 material Substances 0.000 claims description 7
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 claims description 7
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 6
- 108010015598 Chromobacterium viscosum lipase Proteins 0.000 claims description 6
- 230000035764 nutrition Effects 0.000 claims description 5
- 235000014113 dietary fatty acids Nutrition 0.000 claims description 4
- 229930195729 fatty acid Natural products 0.000 claims description 4
- 239000000194 fatty acid Substances 0.000 claims description 4
- 239000012530 fluid Substances 0.000 claims description 4
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims description 3
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 claims description 3
- 229930003427 Vitamin E Natural products 0.000 claims description 3
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims description 3
- 239000011324 bead Substances 0.000 claims description 3
- 150000004665 fatty acids Chemical class 0.000 claims description 3
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims description 3
- 230000001771 impaired effect Effects 0.000 claims description 3
- 235000019155 vitamin A Nutrition 0.000 claims description 3
- 239000011719 vitamin A Substances 0.000 claims description 3
- 235000019165 vitamin E Nutrition 0.000 claims description 3
- 229940046009 vitamin E Drugs 0.000 claims description 3
- 239000011709 vitamin E Substances 0.000 claims description 3
- 229940045997 vitamin a Drugs 0.000 claims description 3
- 108010023302 HDL Cholesterol Proteins 0.000 claims description 2
- 208000019693 Lung disease Diseases 0.000 claims description 2
- 238000010521 absorption reaction Methods 0.000 claims description 2
- 230000001684 chronic effect Effects 0.000 claims description 2
- 230000003930 cognitive ability Effects 0.000 claims description 2
- 230000004064 dysfunction Effects 0.000 claims description 2
- 230000000694 effects Effects 0.000 claims description 2
- 210000003743 erythrocyte Anatomy 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 230000036470 plasma concentration Effects 0.000 claims description 2
- 210000001525 retina Anatomy 0.000 claims description 2
- 229930003231 vitamin Natural products 0.000 claims description 2
- 229940088594 vitamin Drugs 0.000 claims description 2
- 235000013343 vitamin Nutrition 0.000 claims description 2
- 239000011782 vitamin Substances 0.000 claims description 2
- 150000003722 vitamin derivatives Chemical class 0.000 claims description 2
- 238000007789 sealing Methods 0.000 claims 1
- 230000001568 sexual effect Effects 0.000 claims 1
- 241000146387 Chromobacterium viscosum Species 0.000 description 4
- 240000005384 Rhizopus oryzae Species 0.000 description 3
- 235000013752 Rhizopus oryzae Nutrition 0.000 description 3
- 239000012528 membrane Substances 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 230000035622 drinking Effects 0.000 description 2
- 235000013336 milk Nutrition 0.000 description 2
- 239000008267 milk Substances 0.000 description 2
- 210000004080 milk Anatomy 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- 108010028554 LDL Cholesterol Proteins 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 238000004132 cross linking Methods 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 238000005538 encapsulation Methods 0.000 description 1
- -1 fatty acid esters Chemical class 0.000 description 1
- 230000003301 hydrolyzing effect Effects 0.000 description 1
- 230000003100 immobilizing effect Effects 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 235000016236 parenteral nutrition Nutrition 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 108010079522 solysime Proteins 0.000 description 1
Images
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261600207P | 2012-02-17 | 2012-02-17 | |
| US61/600,207 | 2012-02-17 | ||
| US201261719173P | 2012-10-26 | 2012-10-26 | |
| US61/719,173 | 2012-10-26 | ||
| PCT/US2013/026063 WO2013123139A1 (en) | 2012-02-17 | 2013-02-14 | Methods, compositions, and devices for supplying dietary fatty acid needs |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017041428A Division JP6319756B2 (ja) | 2012-02-17 | 2017-03-06 | 食餌性脂肪酸の要求を満たすための方法、組成物、及び装置 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015513532A JP2015513532A (ja) | 2015-05-14 |
| JP2015513532A5 true JP2015513532A5 (https=) | 2016-04-07 |
| JP6198754B2 JP6198754B2 (ja) | 2017-09-20 |
Family
ID=48984683
Family Applications (11)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014557758A Active JP6198754B2 (ja) | 2012-02-17 | 2013-02-14 | 食餌性脂肪酸の要求を満たすための方法、組成物、及び装置 |
| JP2017041428A Active JP6319756B2 (ja) | 2012-02-17 | 2017-03-06 | 食餌性脂肪酸の要求を満たすための方法、組成物、及び装置 |
| JP2017186308A Active JP6452776B2 (ja) | 2012-02-17 | 2017-09-27 | 食餌性脂肪酸の要求を満たすための方法、組成物、及び装置 |
| JP2018084169A Active JP6772214B2 (ja) | 2012-02-17 | 2018-04-25 | 食餌性脂肪酸の要求を満たすための方法、組成物、及び装置 |
| JP2019070482A Active JP6882789B2 (ja) | 2012-02-17 | 2019-04-02 | 食餌性脂肪酸の要求を満たすための方法、組成物、及び装置 |
| JP2020112755A Active JP7142370B2 (ja) | 2012-02-17 | 2020-06-30 | 食餌性脂肪酸の要求を満たすための方法、組成物、及び装置 |
| JP2020201575A Active JP7265787B2 (ja) | 2012-02-17 | 2020-12-04 | 食餌性脂肪酸の要求を満たすための方法、組成物、及び装置 |
| JP2021083664A Active JP7799301B2 (ja) | 2012-02-17 | 2021-05-18 | 食餌性脂肪酸の要求を満たすための方法、組成物、及び装置 |
| JP2022148173A Active JP7645549B2 (ja) | 2012-02-17 | 2022-09-16 | 食餌性脂肪酸の要求を満たすための方法、組成物、及び装置 |
| JP2023222453A Active JP7818832B2 (ja) | 2012-02-17 | 2023-12-28 | 食餌性脂肪酸の要求を満たすための方法、組成物、及び装置 |
| JP2025062370A Pending JP2025106407A (ja) | 2012-02-17 | 2025-04-04 | 食餌性脂肪酸の要求を満たすための方法、組成物、及び装置 |
Family Applications After (10)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017041428A Active JP6319756B2 (ja) | 2012-02-17 | 2017-03-06 | 食餌性脂肪酸の要求を満たすための方法、組成物、及び装置 |
| JP2017186308A Active JP6452776B2 (ja) | 2012-02-17 | 2017-09-27 | 食餌性脂肪酸の要求を満たすための方法、組成物、及び装置 |
| JP2018084169A Active JP6772214B2 (ja) | 2012-02-17 | 2018-04-25 | 食餌性脂肪酸の要求を満たすための方法、組成物、及び装置 |
| JP2019070482A Active JP6882789B2 (ja) | 2012-02-17 | 2019-04-02 | 食餌性脂肪酸の要求を満たすための方法、組成物、及び装置 |
| JP2020112755A Active JP7142370B2 (ja) | 2012-02-17 | 2020-06-30 | 食餌性脂肪酸の要求を満たすための方法、組成物、及び装置 |
| JP2020201575A Active JP7265787B2 (ja) | 2012-02-17 | 2020-12-04 | 食餌性脂肪酸の要求を満たすための方法、組成物、及び装置 |
| JP2021083664A Active JP7799301B2 (ja) | 2012-02-17 | 2021-05-18 | 食餌性脂肪酸の要求を満たすための方法、組成物、及び装置 |
| JP2022148173A Active JP7645549B2 (ja) | 2012-02-17 | 2022-09-16 | 食餌性脂肪酸の要求を満たすための方法、組成物、及び装置 |
| JP2023222453A Active JP7818832B2 (ja) | 2012-02-17 | 2023-12-28 | 食餌性脂肪酸の要求を満たすための方法、組成物、及び装置 |
| JP2025062370A Pending JP2025106407A (ja) | 2012-02-17 | 2025-04-04 | 食餌性脂肪酸の要求を満たすための方法、組成物、及び装置 |
Country Status (19)
| Country | Link |
|---|---|
| US (15) | US9668942B2 (https=) |
| EP (6) | EP4166135A1 (https=) |
| JP (11) | JP6198754B2 (https=) |
| KR (7) | KR102186932B1 (https=) |
| CN (2) | CN104470508B (https=) |
| AU (5) | AU2013221572B2 (https=) |
| BR (1) | BR112014019927B8 (https=) |
| CA (1) | CA2863739C (https=) |
| CL (1) | CL2014002125A1 (https=) |
| CO (1) | CO7071136A2 (https=) |
| DK (2) | DK3384902T3 (https=) |
| EA (1) | EA201491540A8 (https=) |
| ES (2) | ES2674047T3 (https=) |
| IL (10) | IL294717B2 (https=) |
| MX (3) | MX385046B (https=) |
| NZ (2) | NZ629943A (https=) |
| PH (1) | PH12014501828A1 (https=) |
| WO (1) | WO2013123139A1 (https=) |
| ZA (1) | ZA201406101B (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2013221572B2 (en) | 2012-02-17 | 2017-12-21 | Alcresta Therapeutics, Inc. | Methods, compositions, and devices for supplying dietary fatty acid needs |
| EP3062789A1 (en) * | 2013-10-28 | 2016-09-07 | Nestec S.A. | Monoacylglycerols and fat-soluble nutrients for use in the treatment of maldigestion |
| CN106687014A (zh) * | 2014-07-21 | 2017-05-17 | 雅培制药有限公司 | 包含含有磷脂以改善润湿性的营养粉末的营养物递送系统 |
| WO2016073335A1 (en) * | 2014-11-05 | 2016-05-12 | Omthera Pharmaceuticals Inc. | Methods of treatment |
| NO20150142A1 (en) * | 2015-01-30 | 2016-08-01 | Pronova Biopharma Norge As | Enteral feeding device |
| US10258590B2 (en) * | 2015-10-14 | 2019-04-16 | Alcresta Therapeutics, Inc. | Enteral feeding device and related methods of use |
| CA3015664C (en) | 2016-03-10 | 2023-10-31 | Arthrex, Inc. | Systems and methods for preparing a thrombin serum |
| WO2017156379A2 (en) * | 2016-03-10 | 2017-09-14 | Arthrex, Inc. | Systems and methods for preparing protein enhanced serums |
| AR110450A1 (es) * | 2016-12-23 | 2019-03-27 | Pronova Biopharma Norge As | Composición de ácidos grasos omega-3 para la prevención y/o el tratamiento de la caquexia |
| US10716761B2 (en) * | 2017-07-24 | 2020-07-21 | Alcresta Therapeutics, Inc. | Ingestible medical delivery devices |
| US11045396B2 (en) * | 2017-08-17 | 2021-06-29 | Alcresta Therapeutics, Inc. | Devices and methods for the supplementation of a nutritional formula |
| US20190075835A1 (en) | 2017-09-08 | 2019-03-14 | Alcresta Therapeutics, Inc. | Devices and methods for preparing and administering a nutritional formula |
| US11291236B2 (en) * | 2017-09-11 | 2022-04-05 | Alcresta Therapeutics, Inc. | Devices and methods for the preparation of a nutritional formula |
| TWI729831B (zh) * | 2020-05-29 | 2021-06-01 | 蘇建忠 | 鼻胃管餵食系統 |
| US11628124B2 (en) * | 2021-04-28 | 2023-04-18 | Silviya Das | Feeding tube management |
| CN113397981B (zh) * | 2021-05-06 | 2022-09-16 | 山西白求恩医院 | 一种使用方便的儿科用药品喂药器及使用方法 |
| TWI842214B (zh) * | 2022-11-21 | 2024-05-11 | 慈濟學校財團法人慈濟科技大學 | 用於灌食空針的手動攪拌器 |
| CN115590768B (zh) * | 2022-12-15 | 2023-03-10 | 吉林大学第一医院 | 一种基于重症监护用冠心病病人喂药装置 |
| CN116268114A (zh) * | 2023-03-27 | 2023-06-23 | 江南大学 | 一种油脂组合物及其制备方法和应用 |
| WO2025122937A1 (en) * | 2023-12-08 | 2025-06-12 | The Cleveland Clinic Foundation | Micronutrient compositions and systems for treating malnutrition and preventing refeeding syndrome |
| US20260009057A1 (en) * | 2024-07-05 | 2026-01-08 | Alcresta Therapeutics, Inc. | Methods and devices for hydrolyzing fats |
| TWI886047B (zh) * | 2024-09-20 | 2025-06-01 | 艾奇爾生技股份有限公司 | 灌食袋的鼻胃管流速閥門及其使用方法 |
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