JP2015511129A - 高濃度乾燥タンパク質製剤のための再構成方法 - Google Patents

高濃度乾燥タンパク質製剤のための再構成方法 Download PDF

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Publication number
JP2015511129A
JP2015511129A JP2014548210A JP2014548210A JP2015511129A JP 2015511129 A JP2015511129 A JP 2015511129A JP 2014548210 A JP2014548210 A JP 2014548210A JP 2014548210 A JP2014548210 A JP 2014548210A JP 2015511129 A JP2015511129 A JP 2015511129A
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JP
Japan
Prior art keywords
reconstitution
protein
dry
solution
container
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2014548210A
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English (en)
Japanese (ja)
Inventor
ボス ヤン
ボス ヤン
ジョン マクロード アンドリュー
ジョン マクロード アンドリュー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Xstalbio Ltd
Original Assignee
Xstalbio Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xstalbio Ltd filed Critical Xstalbio Ltd
Publication of JP2015511129A publication Critical patent/JP2015511129A/ja
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38—Albumins
    • A61K38/385—Serum albumin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)
  • Degasification And Air Bubble Elimination (AREA)
  • Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
JP2014548210A 2011-12-23 2012-12-24 高濃度乾燥タンパク質製剤のための再構成方法 Pending JP2015511129A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1122430.0 2011-12-23
GBGB1122430.0A GB201122430D0 (en) 2011-12-23 2011-12-23 Reconstitution method for high concentration dry protein formulation
PCT/GB2012/053266 WO2013093525A1 (en) 2011-12-23 2012-12-24 Reconstitution method for high concentration dry protein formulations

Publications (1)

Publication Number Publication Date
JP2015511129A true JP2015511129A (ja) 2015-04-16

Family

ID=45695059

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014548210A Pending JP2015511129A (ja) 2011-12-23 2012-12-24 高濃度乾燥タンパク質製剤のための再構成方法

Country Status (8)

Country Link
US (1) US20140308293A1 (enExample)
EP (1) EP2793852A1 (enExample)
JP (1) JP2015511129A (enExample)
BR (1) BR112014015605A2 (enExample)
CA (1) CA2859287A1 (enExample)
GB (1) GB201122430D0 (enExample)
IN (1) IN2014MN01381A (enExample)
WO (1) WO2013093525A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201313368D0 (en) 2013-07-26 2013-09-11 Xstalbio Ltd Novel Reconstitution devices
US20170274012A1 (en) * 2014-09-03 2017-09-28 Entegrion, Inc. Acceleration of Reconstitution of Plasma Powder by Mixing with Small Beads
US10143625B2 (en) 2015-03-17 2018-12-04 Recon Therapeutics, Inc. Pharmaceutical reconstitution
CN118085011A (zh) 2016-08-17 2024-05-28 勃林格殷格翰国际公司 制备含有生物分子的高度浓缩的液体制剂的方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04502770A (ja) * 1989-04-10 1992-05-21 コーブ　ラボラトリーズ　インコーポレイテッド 新規な凍結乾燥及び再形成赤血球組成物
JPH07304658A (ja) * 1994-05-06 1995-11-21 Immuno Ag 血液凝固疾患の治療のための安定な調製物
JP2008231091A (ja) * 2006-12-14 2008-10-02 Johnson & Johnson Regenerative Therapeutics Llc タンパク質安定化調合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10211227A1 (de) * 2002-03-13 2003-10-02 Aventis Behring Gmbh Verfahren zur Rekonstitution von Iyophilisierten Proteinen
EP1958618A1 (de) * 2007-02-15 2008-08-20 Octapharma AG Verfahren zur Gefriertrocknung mit optimierter Rekonstitution von Biopolymeren
WO2011017070A1 (en) 2009-07-28 2011-02-10 Merck Sharp & Dohme Corp. Methods for producing high concentration lyophilized pharmaceutical formulations

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04502770A (ja) * 1989-04-10 1992-05-21 コーブ　ラボラトリーズ　インコーポレイテッド 新規な凍結乾燥及び再形成赤血球組成物
JPH07304658A (ja) * 1994-05-06 1995-11-21 Immuno Ag 血液凝固疾患の治療のための安定な調製物
JP2008231091A (ja) * 2006-12-14 2008-10-02 Johnson & Johnson Regenerative Therapeutics Llc タンパク質安定化調合物

Also Published As

Publication number Publication date
WO2013093525A1 (en) 2013-06-27
EP2793852A1 (en) 2014-10-29
IN2014MN01381A (enExample) 2015-04-17
GB201122430D0 (en) 2012-02-08
CA2859287A1 (en) 2013-06-27
BR112014015605A2 (pt) 2017-07-04
US20140308293A1 (en) 2014-10-16

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