JP2015510424A - 投与量終了インジケータ - Google Patents
投与量終了インジケータ Download PDFInfo
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- JP2015510424A JP2015510424A JP2014556978A JP2014556978A JP2015510424A JP 2015510424 A JP2015510424 A JP 2015510424A JP 2014556978 A JP2014556978 A JP 2014556978A JP 2014556978 A JP2014556978 A JP 2014556978A JP 2015510424 A JP2015510424 A JP 2015510424A
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- Japan
- Prior art keywords
- container
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- plunger
- injection
- piston rod
- Prior art date
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/50—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
- A61M5/5086—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile for indicating if defective, used, tampered with or unsterile
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31566—Means improving security or handling thereof
- A61M5/3157—Means providing feedback signals when administration is completed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31525—Dosing
- A61M5/31526—Dosing by means of stepwise axial movements, e.g. ratchet mechanisms or detents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31525—Dosing
- A61M5/31528—Dosing by means of rotational movements, e.g. screw-thread mechanisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
- A61M5/3158—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/48—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for varying, regulating, indicating or limiting injection pressure
- A61M5/486—Indicating injection pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/12—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit
- A61M2205/123—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit with incorporated reservoirs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/582—Means for facilitating use, e.g. by people with impaired vision by tactile feedback
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
Description
−弾性部材が弛緩している弛緩状態と、
−弾性部材が緊張している緊張状態
の2つの状態の間で操作され得る。
「注射ペン」は、典型的には、長方形または細長い形の筆記用ペンにいくぶん似た注射装置である。このようなペンは、通常断面図が管状であるが、三角形、長方形もしくは正方形、またはこれらの形状に近いいかなる変化形状の断面図を有することも容易である。
Claims (6)
- 薬液(3)を収容する中空の容器(2)であって、遠位端において前記容器(2)が穿孔可能な膜(4)により閉塞され、かつ、近位端において開放されている、容器(2)と、
前記容器(2)内に設けられたプランジャ(5)であって、前記近位端から前記遠位端へと軸方向前方に移動するプランジャ(5)と、
前記プランジャ(5)を前方に移動させるピストンロッド(20)と、
前記ピストンロッド(20)および前記プランジャ(5)を前記遠位端に向かって前方に移動させるために作動させることができる投与量注射機構であって、前記プランジャ(5)の前方への前記移動により、前記容器(2)に収容された前記薬液(3)中の圧力が上昇する、投与量注射機構と、
前記容器(2)から前記薬液(3)を放出するために、前記膜(4)を通って挿入可能であり、前記放出により前記容器(2)に収容された前記薬液(3)内の前記圧力を減少させる注射針(20)と、
前記投与量注射機構の作動によって、弛緩状態から緊張状態に操作されることができる弾性手段(33)と、を備え、
前記弾性手段(33)は、前記ピストンロッド(20)および前記プランジャ(5)が前方に移動することにより前記圧力が前記薬液(3)中で上昇するときに緊張状態に操作され、前記弾性手段(33)は前記容器内の前記圧力が所定の閾値を超える限り緊張状態を維持し、
前記弾性手段(33)は前記薬液(3)内の前記圧力が前記所定の閾値より低下したときに弛緩状態に戻るよう操作され、
前記弾性手段(33)の弛緩により、前記容器(2)内に収容された前記薬液(3)中の前記圧力が前記所定の閾値より低下したことを聴覚および/または触覚でユーザに知らせる、医療用送達装置。 - 前記容器(2)内で上昇した前記圧力が前記プランジャ(5)および前記ピストンロッド(20)に軸力を加える、請求項1に記載の医療用送達装置。
- 前記力が加えられたときに、前記投与量注射機構の要素が、緊張位置に前記弾性部材(33)を維持する、請求項2に記載の医療用送達装置。
- 前記要素が、半径方向に移動可能な歯車(31)である、請求項3に記載の医療用送達装置。
- 前記要素が、軸方向に移動可能なナット部材(8)である、請求項3に記載の医療用送達装置。
- 前記弾性部材(33)が、皿ばねである、請求項1〜5のいずれか1項に記載の医療用送達装置。
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12156376.1 | 2012-02-21 | ||
EP12156376 | 2012-02-21 | ||
US201261604137P | 2012-02-28 | 2012-02-28 | |
US61/604,137 | 2012-02-28 | ||
PCT/EP2013/052086 WO2013124139A1 (en) | 2012-02-21 | 2013-02-01 | An end of dose indicator |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2015510424A true JP2015510424A (ja) | 2015-04-09 |
JP6336401B2 JP6336401B2 (ja) | 2018-06-06 |
Family
ID=49005030
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2014556978A Expired - Fee Related JP6336401B2 (ja) | 2012-02-21 | 2013-02-01 | 投与量終了インジケータ |
Country Status (5)
Country | Link |
---|---|
US (1) | US20150032050A1 (ja) |
EP (1) | EP2817045B1 (ja) |
JP (1) | JP6336401B2 (ja) |
CN (1) | CN104185489B (ja) |
WO (1) | WO2013124139A1 (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109641110A (zh) * | 2016-08-26 | 2019-04-16 | 赛诺菲-安万特德国有限公司 | 听觉指示器 |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
LT3184136T (lt) | 2010-03-25 | 2021-10-11 | New Injection Systems Ltd | Injektorius |
EP2922588B1 (en) | 2012-11-23 | 2019-02-06 | New Injection Systems Ltd | Auto-injector assembly |
CN103637856B (zh) * | 2013-11-14 | 2015-09-09 | 燕海峰 | 单手直压式连续定量吸排液器 |
CN106456902A (zh) | 2014-06-06 | 2017-02-22 | 伊莱利利公司 | 剂量反馈机构的可旋转端部 |
CA2969349A1 (en) | 2015-01-16 | 2016-07-21 | Eli Lilly And Company | Injection device with end of dose mechanism |
CN112043919B (zh) * | 2020-09-10 | 2022-07-29 | 郑州瑞宇科技有限公司 | 一种胰岛素泵高精度智能控制方法 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS62502178A (ja) * | 1985-09-24 | 1987-08-27 | ベクトン・ディッキンソン・アンド・カンパニー | 圧力検知手段を備えた注射器 |
JP2001517496A (ja) * | 1997-09-25 | 2001-10-09 | ディセトロニック・ライセンシング・アクチェンゲゼルシャフト | 携帯用液体薬剤投与装置 |
JP2008528144A (ja) * | 2005-01-25 | 2008-07-31 | ノボ・ノルデイスク・エー/エス | 用量フィードバック機構を備える注入器具 |
US20100137792A1 (en) * | 2008-12-02 | 2010-06-03 | Sanofi-Aventis Deutschland Gmbh | Medication delivery device and method for operating a medication delivery device |
WO2011003980A1 (en) * | 2009-07-08 | 2011-01-13 | Novo Nordisk A/S | Auto-priming injection device |
WO2011051366A2 (en) * | 2009-10-30 | 2011-05-05 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5391157A (en) * | 1992-10-20 | 1995-02-21 | Eli Lilly And Company | End of dose indicator |
AU696439B2 (en) * | 1995-03-07 | 1998-09-10 | Eli Lilly And Company | Recyclable medication dispensing device |
DE69900026T2 (de) | 1998-01-30 | 2001-05-10 | Novo Nordisk As | Eine injektionsspritze |
ATE299033T1 (de) | 1999-12-09 | 2005-07-15 | Novo Nordisk As | Injektionsvorrichtung |
JP5185620B2 (ja) | 2004-10-21 | 2013-04-17 | ノボ・ノルデイスク・エー/エス | ねじりバネ及び回転表示器を備えた注入装置 |
WO2006128794A2 (en) * | 2005-05-31 | 2006-12-07 | Novo Nordisk A/S | Injection device with visual end-of-content indication |
JP5438117B2 (ja) * | 2008-09-29 | 2014-03-12 | ベクトン ディキンソン フランス | 注射完了を知らせる可聴指摘音発生型可聴式自動注射器具 |
-
2013
- 2013-02-01 JP JP2014556978A patent/JP6336401B2/ja not_active Expired - Fee Related
- 2013-02-01 WO PCT/EP2013/052086 patent/WO2013124139A1/en active Application Filing
- 2013-02-01 US US14/379,643 patent/US20150032050A1/en not_active Abandoned
- 2013-02-01 EP EP13702468.3A patent/EP2817045B1/en not_active Not-in-force
- 2013-02-01 CN CN201380010507.9A patent/CN104185489B/zh not_active Expired - Fee Related
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS62502178A (ja) * | 1985-09-24 | 1987-08-27 | ベクトン・ディッキンソン・アンド・カンパニー | 圧力検知手段を備えた注射器 |
JP2001517496A (ja) * | 1997-09-25 | 2001-10-09 | ディセトロニック・ライセンシング・アクチェンゲゼルシャフト | 携帯用液体薬剤投与装置 |
JP2008528144A (ja) * | 2005-01-25 | 2008-07-31 | ノボ・ノルデイスク・エー/エス | 用量フィードバック機構を備える注入器具 |
US20100137792A1 (en) * | 2008-12-02 | 2010-06-03 | Sanofi-Aventis Deutschland Gmbh | Medication delivery device and method for operating a medication delivery device |
WO2011003980A1 (en) * | 2009-07-08 | 2011-01-13 | Novo Nordisk A/S | Auto-priming injection device |
WO2011051366A2 (en) * | 2009-10-30 | 2011-05-05 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109641110A (zh) * | 2016-08-26 | 2019-04-16 | 赛诺菲-安万特德国有限公司 | 听觉指示器 |
US11369744B2 (en) | 2016-08-26 | 2022-06-28 | Sanofi-Aventis Deutschland Gmbh | Audible indicator |
Also Published As
Publication number | Publication date |
---|---|
US20150032050A1 (en) | 2015-01-29 |
CN104185489B (zh) | 2016-10-26 |
EP2817045B1 (en) | 2016-01-27 |
WO2013124139A1 (en) | 2013-08-29 |
JP6336401B2 (ja) | 2018-06-06 |
EP2817045A1 (en) | 2014-12-31 |
CN104185489A (zh) | 2014-12-03 |
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