JP2015508765A5 - - Google Patents
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- Publication number
- JP2015508765A5 JP2015508765A5 JP2014557034A JP2014557034A JP2015508765A5 JP 2015508765 A5 JP2015508765 A5 JP 2015508765A5 JP 2014557034 A JP2014557034 A JP 2014557034A JP 2014557034 A JP2014557034 A JP 2014557034A JP 2015508765 A5 JP2015508765 A5 JP 2015508765A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- medicament according
- acceptable salt
- obesity
- metoprolol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 claims 13
- 150000003839 salts Chemical class 0.000 claims 8
- 208000008589 Obesity Diseases 0.000 claims 7
- 235000020824 obesity Nutrition 0.000 claims 7
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 6
- IUBSYMUCCVWXPE-UHFFFAOYSA-N metoprolol Chemical compound COCCC1=CC=C(OCC(O)CNC(C)C)C=C1 IUBSYMUCCVWXPE-UHFFFAOYSA-N 0.000 claims 6
- 229960002237 metoprolol Drugs 0.000 claims 6
- 241001465754 Metazoa Species 0.000 claims 5
- 201000010099 disease Diseases 0.000 claims 4
- 230000002265 prevention Effects 0.000 claims 3
- 208000001072 type 2 diabetes mellitus Diseases 0.000 claims 3
- 201000001320 Atherosclerosis Diseases 0.000 claims 2
- 208000032841 Bulimia Diseases 0.000 claims 2
- 206010006550 Bulimia nervosa Diseases 0.000 claims 2
- 208000032928 Dyslipidaemia Diseases 0.000 claims 2
- 208000017170 Lipid metabolism disease Diseases 0.000 claims 2
- 239000008186 active pharmaceutical agent Substances 0.000 claims 2
- 235000021407 appetite control Nutrition 0.000 claims 2
- 208000035475 disorder Diseases 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 230000002526 effect on cardiovascular system Effects 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 241000282412 Homo Species 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- 208000001145 Metabolic Syndrome Diseases 0.000 claims 1
- 241000270666 Testudines Species 0.000 claims 1
- 201000000690 abdominal obesity-metabolic syndrome Diseases 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 239000000969 carrier Substances 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000002552 dosage form Substances 0.000 claims 1
- 210000003608 fece Anatomy 0.000 claims 1
- 239000010871 livestock manure Substances 0.000 claims 1
- KBPHJBAIARWVSC-RGZFRNHPSA-N lutein Chemical compound C([C@H](O)CC=1C)C(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\[C@H]1C(C)=C[C@H](O)CC1(C)C KBPHJBAIARWVSC-RGZFRNHPSA-N 0.000 claims 1
- 229960005375 lutein Drugs 0.000 claims 1
- ORAKUVXRZWMARG-WZLJTJAWSA-N lutein Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=CC(O)CC2(C)C)C ORAKUVXRZWMARG-WZLJTJAWSA-N 0.000 claims 1
- 235000012680 lutein Nutrition 0.000 claims 1
- 239000001656 lutein Substances 0.000 claims 1
- 230000002503 metabolic effect Effects 0.000 claims 1
- 230000000116 mitigating effect Effects 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 239000002831 pharmacologic agent Substances 0.000 claims 1
- KBPHJBAIARWVSC-XQIHNALSSA-N trans-lutein Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C(=CC(O)CC2(C)C)C KBPHJBAIARWVSC-XQIHNALSSA-N 0.000 claims 1
- FJHBOVDFOQMZRV-XQIHNALSSA-N xanthophyll Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C=C(C)C(O)CC2(C)C FJHBOVDFOQMZRV-XQIHNALSSA-N 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261599623P | 2012-02-16 | 2012-02-16 | |
| US61/599,623 | 2012-02-16 | ||
| DKPA201270076 | 2012-02-16 | ||
| DKPA201270076 | 2012-02-16 | ||
| PCT/EP2013/052941 WO2013120935A1 (en) | 2012-02-16 | 2013-02-14 | Pharmaceutical compositions for combination therapy |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015508765A JP2015508765A (ja) | 2015-03-23 |
| JP2015508765A5 true JP2015508765A5 (enExample) | 2016-03-31 |
| JP6203760B2 JP6203760B2 (ja) | 2017-09-27 |
Family
ID=48983571
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014557034A Active JP6203760B2 (ja) | 2012-02-16 | 2013-02-14 | 併用療法のための医薬組成物 |
Country Status (14)
| Country | Link |
|---|---|
| US (5) | US9211271B2 (enExample) |
| EP (1) | EP2814473B1 (enExample) |
| JP (1) | JP6203760B2 (enExample) |
| CN (3) | CN108434129A (enExample) |
| AU (1) | AU2013220424B2 (enExample) |
| CA (1) | CA2864264C (enExample) |
| DK (1) | DK2814473T3 (enExample) |
| EA (1) | EA029543B1 (enExample) |
| ES (1) | ES2704987T3 (enExample) |
| HR (1) | HRP20190050T1 (enExample) |
| LT (1) | LT2814473T (enExample) |
| PL (1) | PL2814473T3 (enExample) |
| SI (1) | SI2814473T1 (enExample) |
| WO (1) | WO2013120935A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2814473B1 (en) * | 2012-02-16 | 2018-10-10 | Saniona A/S | Pharmaceutical compositions for combination therapy |
| WO2015099796A1 (en) * | 2013-12-28 | 2015-07-02 | Intel Corporation | System and method for device action and configuration based on user context detection from sensors in peripheral devices |
| US9579288B2 (en) * | 2015-03-03 | 2017-02-28 | Saniona A/S | Tesofensine and beta blocker combination formulations |
| EP3402473A1 (en) | 2016-01-15 | 2018-11-21 | Saniona A/S | Tesofensine and metoprolol for treatment of hypertension |
| RU2019109050A (ru) | 2016-09-07 | 2020-10-08 | Саниона А/С | Композиции тезофензина |
| US20220160658A1 (en) | 2019-01-07 | 2022-05-26 | Saniona A/S | Tesofensine for reduction of body weight in prader-willi patients |
| CN110297826B (zh) * | 2019-05-31 | 2020-12-11 | 南京理工大学 | 基于json动态解析卫星遥测数据的方法 |
| EP4138830A1 (en) | 2020-04-22 | 2023-03-01 | Saniona A/S | Treatment of hypothalamic obesity |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0677291A3 (en) * | 1991-03-18 | 1996-08-07 | Sepracor Inc | Composition and method containing optically pure S-metoprolol. |
| SK281813B6 (sk) | 1996-02-22 | 2001-08-06 | Neurosearch A/S | Tropánové deriváty, spôsob ich prípravy, použitie a farmaceutická kompozícia s ich obsahom |
| CA2553649A1 (en) | 2004-01-22 | 2005-08-04 | Neurosearch A/S | Compounds for the sustained reduction of body weight |
| US20110118304A1 (en) | 2007-11-20 | 2011-05-19 | Neurosearch A/S | Method for treating over-eating disorders |
| EP2237781A2 (en) | 2007-12-20 | 2010-10-13 | NeuroSearch A/S | Pharmaceutical composition comprising tesofensine or its analogue and an anti-obesity |
| WO2009080693A2 (en) | 2007-12-20 | 2009-07-02 | Neurosearch A/S | Pharmaceutical composition comprising tesofensine or its analogue and a beta blocker |
| US9408837B2 (en) | 2008-05-28 | 2016-08-09 | Kitov Pharmaceutical Ltd. | Ameliorating drug-induced elevations in blood pressure by adjunctive use of antihypertensive drugs |
| EP2814473B1 (en) * | 2012-02-16 | 2018-10-10 | Saniona A/S | Pharmaceutical compositions for combination therapy |
| US9579288B2 (en) * | 2015-03-03 | 2017-02-28 | Saniona A/S | Tesofensine and beta blocker combination formulations |
-
2013
- 2013-02-14 EP EP13703834.5A patent/EP2814473B1/en active Active
- 2013-02-14 CA CA2864264A patent/CA2864264C/en active Active
- 2013-02-14 PL PL13703834T patent/PL2814473T3/pl unknown
- 2013-02-14 DK DK13703834.5T patent/DK2814473T3/en active
- 2013-02-14 ES ES13703834T patent/ES2704987T3/es active Active
- 2013-02-14 WO PCT/EP2013/052941 patent/WO2013120935A1/en not_active Ceased
- 2013-02-14 AU AU2013220424A patent/AU2013220424B2/en not_active Ceased
- 2013-02-14 CN CN201810575583.9A patent/CN108434129A/zh active Pending
- 2013-02-14 EA EA201491532A patent/EA029543B1/ru not_active IP Right Cessation
- 2013-02-14 HR HRP20190050TT patent/HRP20190050T1/hr unknown
- 2013-02-14 SI SI201331313T patent/SI2814473T1/sl unknown
- 2013-02-14 LT LTEP13703834.5T patent/LT2814473T/lt unknown
- 2013-02-14 CN CN201810580312.2A patent/CN108853071A/zh active Pending
- 2013-02-14 CN CN201380020405.5A patent/CN104244935A/zh active Pending
- 2013-02-14 US US14/379,032 patent/US9211271B2/en active Active
- 2013-02-14 JP JP2014557034A patent/JP6203760B2/ja active Active
-
2015
- 2015-11-10 US US14/936,963 patent/US9387184B2/en active Active
-
2016
- 2016-07-11 US US15/206,477 patent/US20170007557A1/en not_active Abandoned
-
2018
- 2018-02-27 US US15/906,350 patent/US20180185304A1/en not_active Abandoned
-
2021
- 2021-07-27 US US17/386,098 patent/US20220016055A1/en not_active Abandoned
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