JP2015505843A5 - - Google Patents

Download PDF

Info

Publication number
JP2015505843A5
JP2015505843A5 JP2014546255A JP2014546255A JP2015505843A5 JP 2015505843 A5 JP2015505843 A5 JP 2015505843A5 JP 2014546255 A JP2014546255 A JP 2014546255A JP 2014546255 A JP2014546255 A JP 2014546255A JP 2015505843 A5 JP2015505843 A5 JP 2015505843A5
Authority
JP
Japan
Prior art keywords
seq
cancer
biologically active
pharmaceutical composition
fusion protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2014546255A
Other languages
English (en)
Japanese (ja)
Other versions
JP2015505843A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CA2012/050899 external-priority patent/WO2013086636A1/en
Publication of JP2015505843A publication Critical patent/JP2015505843A/ja
Publication of JP2015505843A5 publication Critical patent/JP2015505843A5/ja
Pending legal-status Critical Current

Links

JP2014546255A 2011-12-15 2012-12-14 可溶性IGFレセプターFc融合タンパク質およびその使用 Pending JP2015505843A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161576034P 2011-12-15 2011-12-15
US61/576,034 2011-12-15
PCT/CA2012/050899 WO2013086636A1 (en) 2011-12-15 2012-12-14 Soluble igf receptor fc fusion proteins and uses thereof

Publications (2)

Publication Number Publication Date
JP2015505843A JP2015505843A (ja) 2015-02-26
JP2015505843A5 true JP2015505843A5 (enExample) 2016-02-04

Family

ID=48611766

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014546255A Pending JP2015505843A (ja) 2011-12-15 2012-12-14 可溶性IGFレセプターFc融合タンパク質およびその使用

Country Status (9)

Country Link
US (1) US10538575B2 (enExample)
EP (1) EP2791338B1 (enExample)
JP (1) JP2015505843A (enExample)
KR (1) KR20150031217A (enExample)
CN (1) CN104066845A (enExample)
BR (1) BR112014014418A2 (enExample)
CA (1) CA2858389A1 (enExample)
HK (1) HK1202587A1 (enExample)
WO (1) WO2013086636A1 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11566082B2 (en) 2014-11-17 2023-01-31 Cytiva Bioprocess R&D Ab Mutated immunoglobulin-binding polypeptides
JP7095992B2 (ja) * 2014-12-08 2022-07-05 1グローブ バイオメディカル カンパニー, リミテッド 可溶性ユニバーサルadcc増強合成融合遺伝子およびペプチド技術ならびにその使用
ES2834823T3 (es) * 2015-06-04 2021-06-18 Ospedale San Raffaele Srl IGFBP3 y usos del mismo
AU2016272045B2 (en) * 2015-06-04 2018-04-19 Ospedale San Raffaele Srl Inhibitor of IGFBP3/TMEM219 axis and diabetes
US10654887B2 (en) 2016-05-11 2020-05-19 Ge Healthcare Bio-Process R&D Ab Separation matrix
US10889615B2 (en) 2016-05-11 2021-01-12 Cytiva Bioprocess R&D Ab Mutated immunoglobulin-binding polypeptides
JP7106187B2 (ja) 2016-05-11 2022-07-26 サイティバ・バイオプロセス・アールアンドディ・アクチボラグ 分離マトリックスを保存する方法
JP7031934B2 (ja) 2016-05-11 2022-03-08 サイティバ・バイオプロセス・アールアンドディ・アクチボラグ 分離マトリックス
US10703774B2 (en) 2016-09-30 2020-07-07 Ge Healthcare Bioprocess R&D Ab Separation method
US10730908B2 (en) 2016-05-11 2020-08-04 Ge Healthcare Bioprocess R&D Ab Separation method
ES2874974T3 (es) 2016-05-11 2021-11-05 Cytiva Bioprocess R & D Ab Matriz de separación
ES2909833T3 (es) 2016-05-11 2022-05-10 Cytiva Bioprocess R & D Ab Método de limpieza y/o desinfección de una matriz de separación
US12448411B2 (en) 2016-09-30 2025-10-21 Cytiva Bioprocess R&D Ab Separation method
CN106520806B (zh) * 2016-11-03 2018-06-19 宜明细胞生物科技有限公司 一种重组car基因及其载体、car-t细胞和应用
EP3632929A1 (en) 2018-10-02 2020-04-08 Ospedale San Raffaele S.r.l. Antibodies and uses thereof
CN113092392B (zh) * 2021-03-05 2022-11-08 苏州西山中科药物研究开发有限公司 一种检测猴血清中靶向可溶性蛋白的单克隆抗体药物总浓度的通用型方法
CN119708266B (zh) * 2025-02-26 2025-06-06 首玺(广州)医疗科技有限责任公司 一种胰岛素样生长因子-1连接多肽及其在子宫内膜损伤修复中的应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0861267A4 (en) 1995-11-14 2000-02-02 Univ Jefferson INDUCTION AND RESISTANCE TO TUMOR GROWTH BY MEANS OF SOLUBLE IGF-1
PT1699822E (pt) * 2003-12-30 2008-07-30 Merck Patent Gmbh Proteínas de fusão de il-7
MY146381A (en) * 2004-12-22 2012-08-15 Amgen Inc Compositions and methods relating relating to anti-igf-1 receptor antibodies
US7713521B2 (en) * 2005-08-12 2010-05-11 Schering Corporation MCP1 fusions
TW200722436A (en) * 2005-10-21 2007-06-16 Hoffmann La Roche A peptide-immunoglobulin-conjugate
JP2010518140A (ja) * 2007-02-14 2010-05-27 グラクソ グループ リミテッド Igf−1rに対する新規抗体
GB0702888D0 (en) * 2007-02-14 2007-03-28 Glaxo Group Ltd Novel Antibodies
AU2008223541B2 (en) 2007-03-02 2012-04-05 Amgen Inc. Methods and compositions for treating tumor diseases
AU2008281801A1 (en) 2007-08-01 2009-02-05 Glaxo Group Limited Novel antibodies
KR20110044992A (ko) * 2008-07-02 2011-05-03 이머전트 프로덕트 디벨롭먼트 시애틀, 엘엘씨 TGF-β 길항제 다중-표적 결합 단백질
CN102171247A (zh) 2008-07-02 2011-08-31 特鲁比昂药品公司 TNF-α拮抗剂多靶点结合蛋白
JP2011529452A (ja) * 2008-07-29 2011-12-08 ザ・ロイヤル・インスティテューション・フォア・ザ・アドバンスメント・オブ・ラーニング/マクギル・ユニヴァーシティ 抗血管新生薬としての可溶性igf受容体
DK2352763T4 (da) * 2008-10-01 2022-10-17 Amgen Res Munich Gmbh Bispecifikke enkeltkædede antistoffer med specificitet for højmolekylære målantigener
EP2435477A1 (en) * 2009-05-28 2012-04-04 Glaxo Group Limited Antigen-binding proteins

Similar Documents

Publication Publication Date Title
Corre et al. The osteosarcoma microenvironment: a complex but targetable ecosystem
Feldman Hypoxia within the glioblastoma tumor microenvironment: a master saboteur of novel treatments
Qazi et al. Cotargeting ephrin receptor tyrosine kinases A2 and A3 in cancer stem cells reduces growth of recurrent glioblastoma
Yu et al. Potential approaches to the treatment of Ewing's sarcoma
JP2021063120A (ja) 癌を処置するための併用方法
Caffo et al. Innovative therapeutic strategies in the treatment of brain metastases
JP2015529641A5 (enExample)
JP2018521135A5 (enExample)
CN112867503A (zh) 掩蔽的细胞因子缀合物
JP2017171685A5 (enExample)
RU2018105985A (ru) Новый подход к лечению рака с применением иммуномодуляции
EA200701250A1 (ru) Иммуноконъюгаты против интегрина, способы и варианты применения
JP2016535009A5 (enExample)
JP2016502515A5 (enExample)
US20220056450A1 (en) Rna nanostructures and methods of making and using rna nanostructures
JP2017534259A5 (enExample)
JP2019506862A5 (enExample)
EA201792103A1 (ru) Композиции и способы для ингибирования экспрессии генов hif2альфа
Zhao et al. IL10-modified human mesenchymal stem cells inhibit pancreatic cancer growth through angiogenesis inhibition
JP2023532032A (ja) 血液脳関門浸透アプタマー及びその利用
JP2018509423A5 (enExample)
JP2014525412A5 (enExample)
Lu et al. Cancer-associated fibroblasts: central players in cancer hallmarks and therapeutic resistance
EP2545171A4 (en) HJURP PEPTIDES AND VACCINES CONTAINING THEM
Tognolini et al. Ephrin receptor type-A2 (EphA2) targeting in cancer: a patent review (2018–present)