JP2015500886A5 - - Google Patents
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- Publication number
- JP2015500886A5 JP2015500886A5 JP2014548962A JP2014548962A JP2015500886A5 JP 2015500886 A5 JP2015500886 A5 JP 2015500886A5 JP 2014548962 A JP2014548962 A JP 2014548962A JP 2014548962 A JP2014548962 A JP 2014548962A JP 2015500886 A5 JP2015500886 A5 JP 2015500886A5
- Authority
- JP
- Japan
- Prior art keywords
- mucoadhesive
- drug delivery
- delivery device
- bioerodible
- buprenorphine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000003232 mucoadhesive Effects 0.000 claims description 51
- 229940089114 Drug Delivery Device Drugs 0.000 claims description 41
- RMRJXGBAOAMLHD-CTAPUXPBSA-N buprenorphine Chemical compound C([C@]12[C@H]3OC=4C(O)=CC=C(C2=4)C[C@@H]2[C@]11CC[C@@]3([C@H](C1)[C@](C)(O)C(C)(C)C)OC)CN2CC1CC1 RMRJXGBAOAMLHD-CTAPUXPBSA-N 0.000 claims description 33
- 229960001736 buprenorphine Drugs 0.000 claims description 33
- 229920000642 polymer Polymers 0.000 claims description 15
- 238000009792 diffusion process Methods 0.000 claims description 14
- 208000002193 Pain Diseases 0.000 claims description 12
- 230000003364 opioid Effects 0.000 claims description 11
- 208000008035 Back Pain Diseases 0.000 claims description 10
- 208000000094 Chronic Pain Diseases 0.000 claims description 9
- 231100000486 side effect Toxicity 0.000 claims description 7
- 208000008930 Low Back Pain Diseases 0.000 claims description 5
- 230000001684 chronic Effects 0.000 claims description 5
- 206010010774 Constipation Diseases 0.000 claims description 4
- 206010028813 Nausea Diseases 0.000 claims description 4
- 210000002381 Plasma Anatomy 0.000 claims description 4
- 208000004296 Neuralgia Diseases 0.000 claims description 3
- 230000003349 osteoarthritic Effects 0.000 claims description 3
- 230000035839 C max Effects 0.000 claims description 2
- 239000003814 drug Substances 0.000 claims 6
- 229940079593 drugs Drugs 0.000 claims 6
- 206010019233 Headache Diseases 0.000 claims 3
- 231100000869 headache Toxicity 0.000 claims 3
- 206010047700 Vomiting Diseases 0.000 claims 2
- 230000035533 AUC Effects 0.000 claims 1
- 208000002173 Dizziness Diseases 0.000 claims 1
- 230000000275 pharmacokinetic Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 2
- 210000004369 Blood Anatomy 0.000 description 1
- 229940005483 OPIOID ANALGESICS Drugs 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161578755P | 2011-12-21 | 2011-12-21 | |
US61/578,755 | 2011-12-21 | ||
PCT/US2012/071330 WO2013096811A2 (fr) | 2011-12-21 | 2012-12-21 | Dispositifs d'administration transmucosale de médicament pour une utilisation dans le soulagement de la douleur chronique |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2015500886A JP2015500886A (ja) | 2015-01-08 |
JP2015500886A5 true JP2015500886A5 (fr) | 2016-02-04 |
JP6255349B2 JP6255349B2 (ja) | 2017-12-27 |
Family
ID=48669710
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2014548962A Expired - Fee Related JP6255349B2 (ja) | 2011-12-21 | 2012-12-21 | 慢性疼痛軽減に用いるための経粘膜薬物送達デバイス |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP2793870A4 (fr) |
JP (1) | JP6255349B2 (fr) |
KR (4) | KR102026321B1 (fr) |
CN (2) | CN110123792A (fr) |
AU (4) | AU2012358308A1 (fr) |
BR (1) | BR112014015329A2 (fr) |
CA (1) | CA2859859A1 (fr) |
EA (2) | EA201992762A1 (fr) |
HK (1) | HK1203365A1 (fr) |
IL (2) | IL233075A0 (fr) |
IN (1) | IN2014DN06117A (fr) |
MX (2) | MX362217B (fr) |
SG (3) | SG10202012743WA (fr) |
UA (1) | UA118540C2 (fr) |
WO (1) | WO2013096811A2 (fr) |
ZA (1) | ZA201804381B (fr) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2021163529A2 (fr) * | 2020-02-13 | 2021-08-19 | Biodelivery Sciences International, Inc. | Procédés de traitement avec de la buprénorphine |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5800832A (en) | 1996-10-18 | 1998-09-01 | Virotex Corporation | Bioerodable film for delivery of pharmaceutical compounds to mucosal surfaces |
DE19652188C2 (de) * | 1996-12-16 | 2002-02-14 | Lohmann Therapie Syst Lts | Flache Arzneizubereitung zur Applikation und Freisetzung von Buprenorphin oder einer pharmakologisch vergleichbaren Substanz in der Mundhöhle und Verfahren zu ihrer Herstellung |
US5968547A (en) * | 1997-02-24 | 1999-10-19 | Euro-Celtique, S.A. | Method of providing sustained analgesia with buprenorphine |
DE19960154A1 (de) * | 1999-12-14 | 2001-07-12 | Lohmann Therapie Syst Lts | Flache Arzneizubereitung zur transmucosalen Verabreichung von Oxycodon oder einem vergleichbaren Wirkstoff in der Mundhöhle, für die Anwendung in der Schmerztherapie und Suchttherapie |
NZ520554A (en) | 2000-02-08 | 2005-08-26 | Euro Celtique S | Tamper-resistant oral opioid agonist formulations |
CA2445346C (fr) | 2001-04-27 | 2010-04-06 | Ajinomoto Co., Inc. | Derives pyrazolyl-o-glycoside n-substitues et medicament contre le diabete en contenant |
US20110033542A1 (en) | 2009-08-07 | 2011-02-10 | Monosol Rx, Llc | Sublingual and buccal film compositions |
DE102005007859A1 (de) * | 2005-02-21 | 2006-08-24 | Lts Lohmann Therapie-Systeme Ag | Vefahren für eine medikamentöse Kombinations-Behandlung, sowie hierfür geeignete Arzneimittel-Kombinationen |
US20060281775A1 (en) * | 2005-06-14 | 2006-12-14 | Applied Pharmacy Services, Inc. | Two-component pharmaceutical composition for the treatment of pain |
WO2007070632A2 (fr) * | 2005-12-13 | 2007-06-21 | Biodelivery Sciences International, Inc. | Dispositif resistant aux abus pour l'administration transmucosale de medicaments |
KR20090007418A (ko) | 2006-04-12 | 2009-01-16 | 스피날모우션, 인코포레이티드 | 후방 척추 장치 및 방법 |
CN103550136B (zh) | 2006-07-21 | 2016-04-13 | 生物递送科学国际公司 | 吸收增强的经粘膜递送装置 |
EP1897543A1 (fr) * | 2006-08-30 | 2008-03-12 | Euro-Celtique S.A. | Gaufre de buprénorphine pour la thérapie de substitution |
GB0620661D0 (en) * | 2006-10-18 | 2006-11-29 | Pharmasol Ltd | Novel compounds |
US20090270438A1 (en) * | 2006-10-18 | 2009-10-29 | Clive Booles | Novel compositions and formulations |
GB2447016A (en) * | 2007-03-01 | 2008-09-03 | Reckitt Benckiser Healthcare | Buprenorphine/naloxone compositions |
JP2011525536A (ja) * | 2008-06-23 | 2011-09-22 | バイオデリバリー サイエンシーズ インターナショナル インコーポレイティッド | 多方向性粘膜送達装置および使用法 |
US8475832B2 (en) | 2009-08-07 | 2013-07-02 | Rb Pharmaceuticals Limited | Sublingual and buccal film compositions |
-
2012
- 2012-12-21 SG SG10202012743WA patent/SG10202012743WA/en unknown
- 2012-12-21 EA EA201992762A patent/EA201992762A1/ru unknown
- 2012-12-21 EP EP12860757.9A patent/EP2793870A4/fr active Pending
- 2012-12-21 KR KR1020147020237A patent/KR102026321B1/ko active IP Right Grant
- 2012-12-21 CA CA2859859A patent/CA2859859A1/fr not_active Abandoned
- 2012-12-21 WO PCT/US2012/071330 patent/WO2013096811A2/fr active Application Filing
- 2012-12-21 CN CN201910440007.8A patent/CN110123792A/zh active Pending
- 2012-12-21 AU AU2012358308A patent/AU2012358308A1/en not_active Abandoned
- 2012-12-21 KR KR1020197027379A patent/KR20190110628A/ko active Application Filing
- 2012-12-21 SG SG11201403075XA patent/SG11201403075XA/en unknown
- 2012-12-21 JP JP2014548962A patent/JP6255349B2/ja not_active Expired - Fee Related
- 2012-12-21 EA EA201491046A patent/EA034529B1/ru unknown
- 2012-12-21 KR KR1020207038099A patent/KR20210003313A/ko not_active Application Discontinuation
- 2012-12-21 IN IN6117DEN2014 patent/IN2014DN06117A/en unknown
- 2012-12-21 KR KR1020227011298A patent/KR20220047889A/ko not_active Application Discontinuation
- 2012-12-21 UA UAA201406826A patent/UA118540C2/uk unknown
- 2012-12-21 BR BR112014015329A patent/BR112014015329A2/pt not_active Application Discontinuation
- 2012-12-21 MX MX2014007350A patent/MX362217B/es active IP Right Grant
- 2012-12-21 SG SG10201710667YA patent/SG10201710667YA/en unknown
- 2012-12-21 CN CN201280070389.6A patent/CN104125828A/zh active Pending
-
2014
- 2014-06-11 IL IL233075A patent/IL233075A0/en unknown
- 2014-06-18 MX MX2021012154A patent/MX2021012154A/es unknown
-
2015
- 2015-04-22 HK HK15103881.9A patent/HK1203365A1/xx unknown
-
2017
- 2017-11-09 AU AU2017258916A patent/AU2017258916B2/en not_active Ceased
-
2018
- 2018-06-29 ZA ZA2018/04381A patent/ZA201804381B/en unknown
-
2019
- 2019-04-15 AU AU2019202602A patent/AU2019202602A1/en not_active Abandoned
-
2021
- 2021-04-01 AU AU2021202042A patent/AU2021202042A1/en not_active Abandoned
- 2021-07-23 IL IL285091A patent/IL285091A/en unknown
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