MX362217B - Dispositivos de administracion de farmacos por via transmucosal para uso en el alivio del dolor cronico. - Google Patents

Dispositivos de administracion de farmacos por via transmucosal para uso en el alivio del dolor cronico.

Info

Publication number
MX362217B
MX362217B MX2014007350A MX2014007350A MX362217B MX 362217 B MX362217 B MX 362217B MX 2014007350 A MX2014007350 A MX 2014007350A MX 2014007350 A MX2014007350 A MX 2014007350A MX 362217 B MX362217 B MX 362217B
Authority
MX
Mexico
Prior art keywords
chronic pain
drug delivery
transmucosal drug
delivery devices
pain relief
Prior art date
Application number
MX2014007350A
Other languages
English (en)
Other versions
MX2014007350A (es
Inventor
Finn Andrew
Vasisht Niraj
Original Assignee
Biodelivery Sciences Int Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biodelivery Sciences Int Inc filed Critical Biodelivery Sciences Int Inc
Publication of MX2014007350A publication Critical patent/MX2014007350A/es
Publication of MX362217B publication Critical patent/MX362217B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones

Abstract

En la presente se proporcionan métodos para tratar el dolor crónico mediante la administración de dosis bajas de buprenorfina dos veces al día (o una vez al día) a través de un dispositivo de suministro transmucosal de fármacos. Los métodos y dispositivos tratan de manera eficiente el dolor crónico sin efectos secundarios significativos.
MX2014007350A 2011-12-21 2012-12-21 Dispositivos de administracion de farmacos por via transmucosal para uso en el alivio del dolor cronico. MX362217B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161578755P 2011-12-21 2011-12-21
PCT/US2012/071330 WO2013096811A2 (en) 2011-12-21 2012-12-21 Transmucosal drug delivery devices for use in chronic pain relief

Publications (2)

Publication Number Publication Date
MX2014007350A MX2014007350A (es) 2014-09-15
MX362217B true MX362217B (es) 2019-01-09

Family

ID=48669710

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2014007350A MX362217B (es) 2011-12-21 2012-12-21 Dispositivos de administracion de farmacos por via transmucosal para uso en el alivio del dolor cronico.
MX2021012154A MX2021012154A (es) 2011-12-21 2014-06-18 Dispositivos de administracion de farmacos por via transmucosal para uso en el alivio del dolor cronico.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2021012154A MX2021012154A (es) 2011-12-21 2014-06-18 Dispositivos de administracion de farmacos por via transmucosal para uso en el alivio del dolor cronico.

Country Status (16)

Country Link
EP (1) EP2793870A4 (es)
JP (1) JP6255349B2 (es)
KR (4) KR20190110628A (es)
CN (2) CN110123792A (es)
AU (4) AU2012358308A1 (es)
BR (1) BR112014015329A8 (es)
CA (1) CA2859859A1 (es)
EA (2) EA201992762A1 (es)
HK (1) HK1203365A1 (es)
IL (2) IL233075A0 (es)
IN (1) IN2014DN06117A (es)
MX (2) MX362217B (es)
SG (3) SG10201710667YA (es)
UA (1) UA118540C2 (es)
WO (1) WO2013096811A2 (es)
ZA (1) ZA201804381B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021163529A2 (en) * 2020-02-13 2021-08-19 Biodelivery Sciences International, Inc. Methods of treatment with buprenorphine

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5800832A (en) 1996-10-18 1998-09-01 Virotex Corporation Bioerodable film for delivery of pharmaceutical compounds to mucosal surfaces
DE19652188C2 (de) * 1996-12-16 2002-02-14 Lohmann Therapie Syst Lts Flache Arzneizubereitung zur Applikation und Freisetzung von Buprenorphin oder einer pharmakologisch vergleichbaren Substanz in der Mundhöhle und Verfahren zu ihrer Herstellung
US5968547A (en) * 1997-02-24 1999-10-19 Euro-Celtique, S.A. Method of providing sustained analgesia with buprenorphine
DE19960154A1 (de) * 1999-12-14 2001-07-12 Lohmann Therapie Syst Lts Flache Arzneizubereitung zur transmucosalen Verabreichung von Oxycodon oder einem vergleichbaren Wirkstoff in der Mundhöhle, für die Anwendung in der Schmerztherapie und Suchttherapie
CN1423559A (zh) * 2000-02-08 2003-06-11 欧罗赛铁克股份有限公司 包含阿片样激动剂和拮抗剂的控释组合物
EP1389621A4 (en) 2001-04-27 2005-05-11 Ajinomoto Kk N-SUBSTITUTED PYRAZOLYL-O-GLYCOSIDE DERIVATIVES AND DIABETES CONTAINING THEREOF
US20110033542A1 (en) 2009-08-07 2011-02-10 Monosol Rx, Llc Sublingual and buccal film compositions
DE102005007859A1 (de) * 2005-02-21 2006-08-24 Lts Lohmann Therapie-Systeme Ag Vefahren für eine medikamentöse Kombinations-Behandlung, sowie hierfür geeignete Arzneimittel-Kombinationen
US20060281775A1 (en) * 2005-06-14 2006-12-14 Applied Pharmacy Services, Inc. Two-component pharmaceutical composition for the treatment of pain
BRPI0619806A2 (pt) 2005-12-13 2011-10-18 Biodelivery Sciences Int Inc dispositivo para fornecimento de fármacos transmucosal resistente ao abuso
CA2649107A1 (en) 2006-04-12 2007-10-25 Spinal Motion, Inc. Posterior spinal device and method
KR101329496B1 (ko) * 2006-07-21 2013-11-13 바이오딜리버리 사이언시스 인터내셔널 인코포레이티드 향상된 흡수를 갖는 경점막 전달 장치
EP1897543A1 (en) 2006-08-30 2008-03-12 Euro-Celtique S.A. Buprenorphine- wafer for drug substitution therapy
GB0620661D0 (en) * 2006-10-18 2006-11-29 Pharmasol Ltd Novel compounds
US20090270438A1 (en) * 2006-10-18 2009-10-29 Clive Booles Novel compositions and formulations
GB2447016A (en) * 2007-03-01 2008-09-03 Reckitt Benckiser Healthcare Buprenorphine/naloxone compositions
CN105833420A (zh) * 2008-06-23 2016-08-10 生物递送科学国际公司 多向粘膜给药装置及使用方法
US8475832B2 (en) 2009-08-07 2013-07-02 Rb Pharmaceuticals Limited Sublingual and buccal film compositions

Also Published As

Publication number Publication date
KR20220047889A (ko) 2022-04-19
JP2015500886A (ja) 2015-01-08
UA118540C2 (uk) 2019-02-11
HK1203365A1 (en) 2015-10-30
IN2014DN06117A (es) 2015-08-14
EA201992762A1 (ru) 2020-07-31
MX2014007350A (es) 2014-09-15
SG11201403075XA (en) 2014-07-30
KR102026321B1 (ko) 2019-09-27
MX2021012154A (es) 2021-11-03
AU2019202602A1 (en) 2019-05-02
AU2017258916A1 (en) 2017-11-30
AU2021202042A1 (en) 2021-04-29
CN110123792A (zh) 2019-08-16
BR112014015329A2 (pt) 2017-06-13
IL233075A0 (en) 2014-07-31
AU2012358308A1 (en) 2014-07-24
ZA201804381B (en) 2022-12-21
SG10202012743WA (en) 2021-01-28
CA2859859A1 (en) 2013-06-27
AU2017258916B2 (en) 2019-01-17
WO2013096811A3 (en) 2014-07-24
KR20140106720A (ko) 2014-09-03
EP2793870A2 (en) 2014-10-29
CN104125828A (zh) 2014-10-29
EA201491046A1 (ru) 2014-11-28
EA034529B1 (ru) 2020-02-18
KR20210003313A (ko) 2021-01-11
KR20190110628A (ko) 2019-09-30
WO2013096811A2 (en) 2013-06-27
IL285091A (en) 2021-08-31
EP2793870A4 (en) 2016-02-17
JP6255349B2 (ja) 2017-12-27
SG10201710667YA (en) 2018-02-27
BR112014015329A8 (pt) 2017-06-13

Similar Documents

Publication Publication Date Title
MX2023000320A (es) Metodos para modular los niveles de farmaco en plasma mediante el uso de eritrohidroxibupropion.
MY163517A (en) Improved device and method for delivery of a medicament
AU2011328009A8 (en) Compounds and methods for treating pain
PH12015500246A1 (en) Pharmaceutical combinations comprising a b-raf inhibitor, an egfr inhibitor and optionally a pi3k-alpha inhibitor
MX352824B (es) Uso de levocetirizina y montelukast en el tratamiento de influenza, resfriado común e inflamación.
MX370953B (es) Uso de levocetirizina y montelukast en el tratamiento de trastornos autoinmunes.
MX365688B (es) Sistemas de administracion de farmaco y metodos para el tratamiento del cancer de vejiga que comprenden oxaliplatino.
MX2015012315A (es) Uso de levocetirizina y montelukast en el tratamiento de lesion traumatica.
MX2015011905A (es) Uso de levocetirizina y montelukast en el tratamiento de la vasculitis.
WO2018102261A3 (en) Boronic derivatives hydroxamates as anticancer agents
MX2015010296A (es) Tratamiento de formas progresivas de esclerosis multiple con laquinimod.
WO2011100769A3 (en) Kinase modulators for the treatment of cancer
NZ707636A (en) Ingenol-derived compounds that can be used for treating cancer
MX2021012154A (es) Dispositivos de administracion de farmacos por via transmucosal para uso en el alivio del dolor cronico.
CL2012000488A1 (es) Uso de carbon vegetal para tratar una sobredosis de etexilato de dabigatran.
EA201590760A1 (ru) Применение бремеланотида в терапии женской сексуальной дисфункции
UA86338U (ru) Способ лечения беременных с гестационным диабетом
AU2014900743A0 (en) A method to deliver pain relief with a reduced risk of overdose, using 1:1, 2:1, 3:1 and 4:1 mixtures of naloxone and fentanyl for nasal administration.
NZ724912A (en) Transmucosal drug delivery devices for use in chronic pain relief
UA69222U (ru) Способ рефлексотерапии больных с отдаленными последствиями черепно-мозговой травмы
UA67427U (ru) Способ лечения фиброзно-кавернозных форм органного туберкулеза
UA33217U (ru) Способ лечения больных хроническими дерматозами
UA45538U (ru) Способ лечения астенического синдрома у пациентов урологического профиля

Legal Events

Date Code Title Description
FG Grant or registration