JP2015222539A - Cell storage system, cell storage method and program - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a cell storage system capable of reducing a risk of losing all of same kind of cells, even when an accident such as natural disaster occurs.SOLUTION: A cell storage system S comprises: a device 11 for reading each container ID from each of recording media provided on plural containers; a device 10 for sending the plural container IDs read from the device 11; a device 40 for allocating the plural container IDs received from the device 10 to an ID of two or more devices 22, associating the container IDs and the ID of the devices 22 to which the container IDs are allocated and storing them in a database; a device 21 for reading the container ID from the recording medium disposed on the container which is going to be stored in the device 22; and a device 20 for sending the container ID read from the device 21 to the device 40. The device 40 is configured to determine whether or not the ID of the devices 22 which are going to store the containers matches the ID of the device 22 associated with the container IDs received from the device 20 and recorded, based on the information recorded in the database.

Description

  The present invention relates to a system, method, program, and the like for dispersing and storing cells.

  A system for storing cells collected from a living body for regenerative medicine and infertility treatment is known (for example, Patent Document 1). In Patent Document 1, when identification information is given to cells collected from a living body and a series of processes including at least two processes among acceptance, separation, differentiation induction, culture, storage, inspection, and shipment are performed. A cell management system for managing cells has been proposed.

JP 2005-332046 A

  However, since the system proposed in Patent Document 1 does not have a technology for distributing a plurality of containers containing the same type of cells and allocating storage destinations, natural disasters, failure of a device for storing cells, power failure, etc. There is a high risk of losing all cells of the same type in a plurality of containers stored in the same cell storage device when an accident such as disconnection of infrastructure or human error occurs.

  The present invention has been made to solve the above-described problems, and its purpose is to cause an accident such as a natural disaster, a failure of a device for storing cells, an infrastructure disconnection such as a power failure, or a human error. However, it is to provide a cell storage system or the like that can reduce the risk of losing all the same type of cells.

  In order to solve the above-described problems, a cell storage system or the like according to the present invention is a cell storage system or the like for storing a plurality of containers in which cells of the same type are dispersed in two or more cell storage devices. Container identification information acquiring means for acquiring container identification information assigned to each of the plurality of containers, and assigning means for assigning the container identification information to cell storage device identification information assigned to two or more cell storage devices. Recording control means for associating and recording the container identification information and the cell storage device identification information assigned with the container identification information in a database, and the container identification given to the container to be stored in the cell storage device Based on information stored in the database in association with the storage container identification information acquisition means for acquiring information and the recording control means, the container identification information is The cell storage device identification information recorded in association with the container identification information acquired by the storage container identification information acquisition means, and the cell storage device identification information given to the cell storage device that intends to store the given container; Determining means for determining whether or not they match.

  The cell storage system and the like according to the present invention reduce the risk of losing all of the same type of cells even if an accident such as a natural disaster, failure of a device that stores cells, infrastructure disconnection such as a power failure, human error, etc. occurs. Can do.

It is a block diagram which shows the structure of one Embodiment of the cell storage system which concerns on this invention. It is a block diagram which shows the structure of the administrator terminal device used for the cell storage system of one Embodiment. It is a block diagram which shows the structure of the cell storage terminal device used for the cell storage system of one Embodiment. It is a block diagram which shows the structure of the server apparatus used for the cell storage system of one Embodiment. It is a figure which shows an example of the various information linked | related with cell storage apparatus ID and its cell storage apparatus ID recorded on the cell storage apparatus database in the server apparatus in one Embodiment. It is a figure which shows an example of the various information linked | related with container ID and the container ID recorded on the container database in the server apparatus in one Embodiment. It is a flowchart which shows the process for assigning the some container ID with which the same container group ID was set performed to the 2 or more cell storage apparatus performed in the cell storage system of one Embodiment. It is a flowchart (the 1) which shows the process for issuing the recording medium performed in the cell storage system of one Embodiment. It is a flowchart (the 1) which shows the process for outputting the image data performed in the cell storage system of one Embodiment. It is a flowchart which shows the process for determining whether there is no problem in the storage place of a container performed in the cell storage system of one Embodiment. It is a flowchart (the 2) which shows the process for outputting the image data performed in the cell storage system of one Embodiment. It is a flowchart which shows the process performed in the cell storage system of one Embodiment for setting new container ID to the new container in which the culture of the cell was put. It is a flowchart (the 2) which shows the process for issuing the recording medium performed in the cell storage system of one Embodiment.

  Hereinafter, embodiments according to the present invention will be described with reference to the drawings. In the following embodiments, a cell storage system including an administrator terminal device, two or more cell storage devices, and a server device connected to the administrator terminal device and two or more cell storage devices via a network. On the other hand, it is an embodiment when the cell storage system and the cell storage method according to the present invention are applied. However, the present invention is not limited to the following embodiments within the scope including the technical idea.

[1] Configuration and Outline of Cell Storage System First, the configuration and outline of the cell storage system S in the present embodiment will be described with reference to FIG. FIG. 1 is a system configuration diagram showing the configuration of the cell storage system S in the present embodiment. Although two administrator terminal devices 10 are shown in FIG. 1, the number of administrator terminal devices 10 may be one or two or more. In FIG. 1, two cell storage terminal devices 20 are shown, but the number of cell storage terminal devices 20 may be two or three or more.

  The cell storage system S of this embodiment is for storing and managing a plurality of containers holding various cells sent from a client (shipping source) such as a hospital or research facility in a suitable environment. System.

  In particular, the cell storage system S of the present embodiment is an egg cell, sperm cell, fertilized egg cell, fibroblast, hematopoietic stem cell collected at the same time from the same individual requested to be stored by a client such as a hospital or research facility. Allogeneic cells such as neural stem cells, and eggs collected at the same time from eggs of the same individual and sperm collected at the same time from the testes of the same individual, in vitro fertilized egg cells, cultured cells, hybridomas, etc. Are stored in a plurality of cell storage devices 22 installed in different facilities, different rooms, or the same room. The “same species” means that the taxonomic types are the same, and more specifically, the morphology and specific markers are the same. The “specific marker” is an index for identifying different cell types, and means a messenger RNA (mRNA) that is specifically expressed in various cells, a peptide or protein that is specifically produced, and the like. .

  Specifically, as shown in FIG. 1, the cell storage system S of the present embodiment includes a plurality of administrator terminal devices 10 possessed by an administrator who manages the same type of cells sent from the client, and the same type. A cell storage terminal device 20 installed around the cell storage device 22 for storing and managing the cells, a network 30, a server device 40, and a base station BS connected to the network 30. .

  The network 30 includes, for example, a public telephone line network (hereinafter referred to as “long-distance communication network”) including a mobile phone network, an IP (Internet Protocol) network such as a short-distance wireless network, or both of which are interconnected. Has been. However, the configuration of the network 30 is not limited to this.

The administrator terminal device 10 is an information communication terminal device such as a personal computer (PC), a tablet information terminal device, a smartphone, or a workstation. In particular, the administrator terminal device 10 is connected to the recording medium reading device 11 and the recording medium issuing device 12, and
(1A-1) Container identification information given to each of a plurality of containers from a recording medium provided in the plurality of containers when a client requests storage of a plurality of containers containing the same type of cells ( Hereinafter referred to as “container ID”) and processing for reading information such as cell storage environment condition information relating to the storage environment condition of the cells placed in the container to which the container ID is assigned,
(1A-2) Issuing (printing) a recording medium in which information such as container group identification information (hereinafter referred to as “container group ID”) set for a plurality of containers containing the same type of cells is recorded. Processing (hereinafter referred to as “recording medium issuance processing of the administrator terminal device 10”),
Etc. are executed.

The recording medium on which information such as container ID and cell storage environmental condition information is recorded may be attached to the container by the client, or may be attached to the container by the administrator based on the request of the client. You may provide in a container. Examples of cell storage environmental conditions include, but are not limited to, cell storage temperature, cell storage humidity, and cell storage CO ₂ concentration.

Furthermore, the recording medium is, for example, a label on which a code such as a barcode, a two-dimensional barcode, an alphanumeric character code, or the like is recorded, and information such as a container ID is recorded on the recording medium. The recording medium reader 11 is a code reader that can read a barcode or information including information such as a container ID. Other,
(A) an imaging device such as a camera that captures an alphanumeric character code including information such as a container ID and creates image data;
(A) An apparatus including an OCR machine that reads an alphanumeric character code from the image data may be used. The recording medium issuing device 12 is, for example, a printing device that prints a code such as a barcode, a two-dimensional barcode, and an alphanumeric character code on a label.

  On the other hand, since the administrator terminal device 10 communicates with the server device 40, identification information unique to each administrator terminal device 10 set in advance (hereinafter referred to as “manager terminal device ID”). Is used. In addition, the communication terminal device 10 has a browser function constructed by a markup language such as XML (extensible Markup Language), and executes an operation input instruction and an operation confirmation by the administrator using the browser function. Data exchange with the server device 40 is executed via the browser function.

And the administrator terminal device 10 is
(1B-1) Each container ID read from each recording medium provided in each of a plurality of containers (hereinafter simply referred to as “a plurality of containers”) containing the same type of cells by the recording medium reader 11 and Send information such as cell storage environmental condition information to the server device 40,
(1B-2) Information on the installation location of the cell storage device 22 for storing each container or each container in a distributed manner according to the transmitted information such as each container ID and cell storage environmental condition information The server device 40 receives a notification that
(1B-3) A process of displaying the received information or notification so as to be viewable to the administrator is executed.
It has a configuration.

The cell storage terminal device 20 is an information communication terminal device such as a personal computer (PC), a tablet information terminal device, a smartphone, or a workstation. In particular, the cell storage terminal device 20 is connected to a recording medium reading device 21 and a recording medium issuing device 23,
(2A-1) When reading from the recording medium provided in the container to be stored in the cell storage device 22, such as processing for reading information such as the container ID given to the container, or when taking out from the cell storage device 22, A process of reading information such as a container ID assigned to the container from a recording medium provided in the container to be returned to the cell storage device 22, and
(2A-2) a process of issuing (printing) a recording medium that records information such as a new container ID set in a new container containing a cell culture and storage environment condition information of the culture;
Etc. are executed.

  Similarly to the administrator terminal device 10, the cell storage terminal device 20 has a browser function constructed by a markup language, and uses the browser function to execute an operation input instruction and an operation confirmation by the operator. Using the identification information unique to each cell storage terminal device 20 set in advance (hereinafter referred to as “cell storage terminal device ID”), data is exchanged with the server device 40 via the browser function. It has the composition to do.

And the cell storage terminal device 20 is:
(2B-1) When the recording medium reading device 21 returns the recording medium provided in the container to be stored in the cell storage device 22 or the container taken out from the cell storage device 22, the recording provided in the container Information such as the container ID read from the medium and cell storage device identification information (hereinafter referred to as “cell storage device ID”) unique to each cell storage device 22 assigned to the cell storage device 22 is stored in the server device 40. Send
(2B-2) A notification that there is no problem in the container storage location or that there is a problem in the container storage location is received from the server device 40 according to the transmitted information such as the container ID and the cell storage device ID. And
(2B-3) A process of displaying the received notification so as to be viewable to the worker is executed.
It has a configuration.

In addition, the cell storage terminal device 20
(2C-1) Operation for reading information such as container ID from a recording medium provided in the container by the recording medium reading device 21, information indicating that the cells have been taken out from the container and cultured, and storage environment conditions for the culture of the cells When the information such as the container ID, the information indicating that the cells have been taken out from the container and cultured, and the storage environment condition information of the culture are detected by the input operation of the information, the information is transmitted to the server device 40. ,
(2C-2) The server device 40 receives information such as a new container ID set in the new container containing the cell culture and storage environment condition information of the culture according to the transmitted information. And
(2C-3) A process of issuing (printing) a recording medium in which the received information is recorded (hereinafter referred to as “recording medium issuing process of the cell storage terminal device 20”) is executed.
It has a configuration.

  The cell storage device 22 is a device for storing cells. For example, the cell storage device 22 is a culture device for culturing cells, a freezer such as a liquid nitrogen tank or a deep freezer for storing cells in a frozen state, a refrigerator for storing cells in a refrigerator, and the like. In the present embodiment, the cell storage terminal device 20 and the cell storage device 22 are provided separately, but the cell storage device 22 may be provided with the function of the cell storage terminal device 20 to be integrated.

  The server device 40 is linked to the administrator terminal device 10 or the cell storage terminal device 20, stores a plurality of containers dispersed in the two or more cell storage devices 22, and is based on the container ID assigned to each of the plurality of containers. It is a storage management device used to execute each data processing for managing the storage destination of the cell storage device 22 that stores each container.

In particular, the server device 40 manages the administrator terminal device ID, the password set in the administrator terminal device ID, the access authority of the administrator terminal device 10 having the administrator terminal device ID, and the like.
(3A-1) Cell storage environmental conditions, etc., which are read by the recording medium reading device 11 and related to the storage ID of each of the plurality of containers and the storage environmental conditions of the cells placed in the container to which the container ID is assigned Receiving information from the administrator terminal device 10,
(3A-2) Set a container group ID for the container ID of a plurality of containers,
(3A-3) Information including the container group ID set for the container IDs of a plurality of containers is transmitted to the corresponding administrator terminal device 10, and
(3A-4) Control to record each container ID, container group ID, and cell storage environmental condition information in the database 400 in association with each other,
(3A-5) In order to determine the cell storage device 22 in which each container is dispersed and stored, a process of assigning container IDs of a plurality of containers to two or more cell storage device IDs is performed.
(3A-6), controlling each container ID, container group ID, and cell storage environment condition information to be recorded in the database in association with each other, and associating the container ID with the cell storage device ID to which the container ID is assigned A process of controlling to record in the database 400.
It has a configuration.

In addition, the server device 40 provides an administrator with an installation location of the cell storage device 22 that stores a plurality of containers.
(3B-1) Information on the installation location of the cell storage device 22 recorded in association with the cell storage device ID based on the cell storage device IDs respectively associated with the plurality of container IDs for which the same container group ID is set. From the database 400,
(3B-2) Information such as the container IDs of the plurality of containers is transmitted associating each container ID with information on the location of the cell storage device 22 that stores the container to which the container ID is assigned. To the administrator terminal device 10
It has the structure which performs a process.

Further, the server device 40 is installed in the vicinity of the cell storage terminal device 20, the password set in the cell storage terminal device ID, the access authority of the cell storage terminal device 20 having the cell storage terminal device ID, and the cell storage terminal device 20. While managing information on the location of the cell storage device 22, cell storage environment condition information of the cell storage device 22, availability information of the cell storage device 22, etc.
(3C-1) When the container is taken out from the cell storage device 22 or the container ID given to the container to be stored in the cell storage device 22 read by the recording medium reading device 21, the cell storage device Receiving from the cell storage terminal device 20 information such as the container ID assigned to the container to be returned to 22 and the cell storage device ID assigned to the cell storage device 22;
(3C-2) Based on the information that associates the container ID and the cell storage device ID recorded in the database 400, the cell storage device ID received from the cell storage terminal device 20, that is, the container to which the container ID is assigned. The cell storage device ID assigned to the cell storage device 22 to be stored or the cell storage device ID assigned to the cell storage device 22 to return the container to which the container ID is assigned is the received container ID. Whether the cell storage device ID recorded in association with the
(3C-3) If it is determined that the results match, the cell storage terminal device 20 that has transmitted information such as the container ID and the cell storage device ID is notified that there is no problem in the storage location of the container. At the same time, the container assigned with the container ID is stored or returned to the cell storage apparatus 22 assigned with the cell storage apparatus ID recorded in the database 400 in association with the container ID. Control to record the container storage history information shown,
(3C-4) If it is determined that the results do not match, the cell storage terminal device 20 that has transmitted the information such as the container ID and the cell storage device ID is notified that there is a problem in the storage location of the container. To
And the like.

Furthermore, when the server device 40 performs a process of assigning a plurality of container IDs having the same container group ID to two or more cell storage device IDs,
(3D-1) The same container group ID is set based on the cell storage environment condition information of the plurality of containers received from the administrator terminal device 10 and the availability information of the cell storage device 22 recorded in the database 400. Cell storage device IDs that can be assigned a plurality of container IDs,
(3D-2) Determine whether there are two or more extracted cell storage device IDs,
(3D-3) If it is determined that there are two or more cell storage device IDs, a plurality of container IDs in which the same container group ID is set are assigned to the two or more extracted cell storage device IDs,
(3D-4) If it is determined that there are not two or more cell storage device IDs, the administrator terminal device 10 is notified that each container cannot be distributed and stored.
And the like.

On the other hand, the server device 40
(3E-1) Receiving and acquiring information such as the container ID, information indicating that the cells were removed from the container and cultured, and storage environment condition information of the culture from the cell storage terminal device 20,
(3E-2) Set a new container ID in a new container containing the cell culture,
(3E-3) Control to record the new container ID set in the new container and the storage environment condition information of the culture in the database 400 in association with each other,
(3E-4) Control so that the container ID assigned to the container from which the cell is taken out and the new container ID are associated and recorded in the database 400.
It has the structure which performs a process.

  With such a configuration, in the system S of the present embodiment, a plurality of containers containing the same type of cells requested to be stored by the client are installed in different facilities, different rooms, or the same room. In addition, two or more cell storage devices 22, in particular, two or more cell storage devices that satisfy the cell storage environment condition and can store the containers can be allocated and dispersed. Since a plurality of containers can be stored and managed correctly in the storage device 22, all cells of the same type can be stored even if an accident such as a natural disaster, a failure of the cell storage device 22, an interruption of infrastructure such as a power failure, or a human error occurs. The risk of losing can be reduced.

  Further, in the cell storage system S of the present embodiment, when two or more cell storage devices 22 that satisfy the storage environment conditions of the cells and can store the containers do not exist, The administrator is notified that multiple containers containing cells of the same type cannot be distributed and stored, so the administrator knows that distributed management is not possible when receiving multiple containers containing the same type of cells. Can be done.

  Further, in the cell storage system S of the present embodiment, even when the container taken out from the cell storage device 22 is to be returned to the cell storage device 22, the cell storage device ID of the cell storage device 22 to be returned is used. Therefore, the container taken out from the cell storage device 22 can be correctly returned to the original location.

  In the cell storage system S of the present embodiment, when storing the container in the cell storage device 22 or when returning the container taken out from the cell storage device 22 to the cell storage device 22, a message to that effect is stored in the database. Since the container storage history information is recorded in 400, the administrator and the operator can confirm that a plurality of containers are distributed and stored, and in which cell storage device 22 the container is stored, and , It is possible to know when it was stored or when it was returned.

  Note that the cell storage system S accesses the server device 40 via the network 30 so that the requester can confirm and grasp the information by authenticating the requester ID and the like. For example, an information communication terminal device such as a personal computer (PC) may be further provided as a client terminal device.

  In addition to the above, in the cell storage system S of the present embodiment, the container ID of the container in which the cell is placed and the new container ID of the new container in which the culture of the cell is placed are recorded in association with each other. Therefore, the manager manages the cell requested to be stored by the client in association with the cell culture, for example, a differentiated cell cell, a subcultured cell cell, a tissue culture of the cell, etc. Can be done.

  In addition, when there are a plurality of new containers in which cell cultures are placed, the same processing as that of the plurality of containers requested by the client is performed, and the plurality of new containers are stored in two or more cell storage devices. 22 may be distributed and stored. When all the cells are taken out from the container and cultured, the container ID assigned to the container from which the cells are taken out may be set in a new container.

[2] Administrator Terminal Device Next, the configuration of the administrator terminal device 10 of this embodiment will be described using FIG. FIG. 2 is a block diagram illustrating a configuration of the administrator terminal device 10 according to the present embodiment.

  As shown in FIG. 2, the administrator terminal device 10 of the present embodiment issues a recording medium that executes various processes including a communication control unit 110 that communicates with the server device 40 and a process for issuing a recording medium. A processing unit 140, an administrator terminal management control unit 130 that controls each unit of the administrator terminal device 10, a ROM / RAM 150 that is used to control each unit, a display unit 160, and a display control unit 161 that controls the display unit 160. And an operation unit 170 used for inputting an operation of the administrator. Note that the above-described units are connected to each other by a bus B, and data transfer is performed between the components.

  The communication control unit 110 is a predetermined network interface, establishes a communication line with the server device 40, and exchanges various data with the server device 40.

  In particular, the communication control unit 110 transmits information such as container IDs and cell storage environmental condition information of a plurality of containers read by the recording medium reading device 11 to the server device 40 in conjunction with the recording medium reading device 11. .

  The communication control unit 110 responds to the transmission of information such as each container ID and cell storage environmental condition information of the plurality of containers to the server apparatus 40, and the container group ID set for the plurality of containers by the server apparatus 40. And information on the installation location of the cell storage device 22 that stores each container, or notification that each container cannot be distributed and stored is received from the server device 40.

  The recording medium issuance processing unit 140 implements the recording medium issuance processing of the administrator terminal device 10 by executing an application recorded in the ROM / RAM 150 in conjunction with the communication control unit 110. Note that the recording medium issuance processing unit 140 may be implemented as a function when the CPU (central processing unit) constituting the administrator terminal management control unit 130 executes the application.

  The recording medium issuance processing unit 140 is linked to the server device 40 and the recording medium issuance device 12, and issues a recording medium that records information such as container group IDs set by the server device 40 for a plurality of containers. The recording medium issuing process of the person terminal device 10 is executed.

  Specifically, the recording medium issuance processing unit 140 instructs the recording medium issuance apparatus 12 to issue a recording medium on which information such as a container group ID received from the server apparatus 40 is recorded to a plurality of containers. In response to this instruction, the recording medium issuing device 12 issues a recording medium on which information such as a container group ID is recorded to a plurality of containers, and the issued recording medium is attached to the plurality of containers by the administrator. .

  The administrator terminal management control unit 130 is mainly configured by a central processing unit (CPU), and integrally controls each unit of the administrator terminal device 10 by executing a program. Specifically, the administrator terminal management control unit 130 performs login processing for each administrator and various other controls based on a login request by an operation of the administrator.

  Various programs necessary for driving the administrator terminal device 10 are recorded in the ROM / RAM 150. In particular, the ROM / RAM 150 is used as a work area during execution of each program.

  The display unit 160 is configured by a panel of liquid crystal elements or EL (Electro Luminescence) elements, and displays a predetermined image based on the image data generated by the display control unit 161.

  The display control unit 161 generates image data necessary to display a predetermined image on the display unit 160 under the control of the recording medium issuance processing unit 140 or the administrator terminal management control unit 130, and the generated image data is displayed. The information is output to the display unit 160. Examples of the predetermined image include an image received from the server device 40 indicating information on the location of the cell storage device 22 that stores each container, a notification that the containers cannot be distributed, and the like. be able to.

  The operation unit 170 includes various confirmation buttons, operation buttons for inputting operation commands, a number of keys such as a numeric keypad, and a touch sensor provided on the display unit 160, and is used when performing each operation. It has become.

[3] Cell Storage Terminal Device Next, the configuration of the cell storage terminal device 20 of the present embodiment will be described using FIG. FIG. 3 is a block diagram showing a configuration of the cell storage terminal device 20 of the present embodiment.

  As shown in FIG. 3, the cell storage terminal device 20 according to the present embodiment issues a recording medium issuance that executes various processes including a communication control unit 210 that communicates with the server device 40 and a process for issuing a recording medium. A processing unit 240, a cell storage terminal management control unit 230 that controls each unit of the cell storage terminal device 20, a ROM / RAM 250 used for control of each unit, a display unit 260, and a display control unit 261 that controls the display unit 260 And an operation unit 270 used for inputting an operation of the administrator. Note that the above-described units are connected to each other by a bus B, and data transfer is performed between the components.

  The communication control unit 210 is a predetermined network interface, establishes a communication line with the server device 40, and exchanges various data with the server device 40.

  In particular, the communication control unit 210 transmits information such as the container ID and the cell storage device ID read by the recording medium reading device 21 to the server device 40 in conjunction with the recording medium reading device 21.

  In response to the transmission of information such as the container ID and the cell storage device ID to the server device 40, the communication control unit 210 notifies that there is no problem in the container storage location or that there is a problem in the container storage location. And received from the server device 40.

  The communication control unit 210 transmits information such as the container ID read by the recording medium reading device 21 to the server device 40 in cooperation with the recording medium reading device 21. Further, the communication control unit 210 operates in conjunction with the operation unit 270 and the cell storage terminal management control unit 230, and the cell storage terminal management control unit 230 detects the cell from the container detected by the input operation using the operator operation unit 270. Is sent to the server device 40 and information indicating that it has been cultured and storage environment condition information of the culture.

  The communication control unit 210 puts the cell culture in response to the transmission of information such as the container ID to the server device 40, information indicating that the cell has been removed from the container and cultured, and storage environment condition information of the culture. The new container ID set for the new container and information such as the storage environment condition information of the culture are received from the server device 40.

  The recording medium issuance processing unit 240 implements the recording medium issuance processing of the cell storage terminal device 20 by executing an application recorded in the ROM / RAM 250 in conjunction with the communication control unit 210. In addition, the recording medium issue processing unit 240 may be implemented as a function when the CPU (central processing unit) constituting the cell storage terminal management control unit 230 executes the application.

  The recording medium issuance processing unit 240 is linked with the communication control unit 210, the server device 40, and the recording medium issuance device 23, and is a new container containing a cell culture received from the server device 40 via the communication control unit 210. The recording medium issuance process of the cell storage terminal device 20 is performed to issue a recording medium in which information such as the new container ID set in the above and the storage environment condition information of the culture is recorded.

  Specifically, the recording medium issuance processing unit 240 instructs the recording medium issuance apparatus 23 to issue a recording medium in which information such as a new container ID received from the server apparatus 40 is recorded to the new container. . In response to this instruction, the recording medium issuing device 23 issues a recording medium in which information such as a container ID is recorded to a new container, and the issued recording medium is attached to the new container by the operator.

  The cell storage terminal management control unit 230 is mainly configured by a central processing unit (CPU), and integrally controls each unit of the cell storage terminal device 20 by executing a program. Specifically, the cell storage terminal management control unit 230 performs login processing of each worker and various other controls based on a login request by the operator's operation.

  Various programs necessary for driving the cell storage terminal device 20 are recorded in the ROM / RAM 250. In particular, the ROM / RAM 250 is used as a work area during execution of each program.

  The display unit 260 is configured by a panel of a liquid crystal element or an EL (Electro Luminescence) element, and displays a predetermined image based on the image data generated by the display control unit 261.

  The display control unit 261 generates image data necessary to display a predetermined image on the display unit 260 under the control of the recording medium issuance processing unit 240 or the cell storage terminal management control unit 230, and generates the generated image data. The information is output to the display unit 260. Examples of the predetermined image include an image that is received from the server device 40 and indicates that there is no problem in the storage location of the container or a notification that there is a problem in the storage location of the container.

  The operation unit 270 includes various confirmation buttons, operation buttons for inputting operation commands, a number of keys such as a numeric keypad, and a touch sensor provided on the display unit 260, and is used when performing each operation. It has become.

[4] Server Device Next, the configuration of the server device 40 of the present embodiment will be described with reference to FIGS. FIG. 4 is a block diagram showing a configuration of the server device 40 of the present embodiment, and FIG. 5 shows cell storage device IDs recorded in the cell storage device database 403 in the server device 40 of the present embodiment. FIG. 6 is a diagram showing an example of various types of information associated with the cell storage device ID, and FIG. 6 shows various types of information associated with the container ID and the container ID recorded in the container database 404 in the server device 40 of the present embodiment. It is a figure which shows an example.

  As shown in FIG. 4, the server device 40 of the present embodiment includes information on the administrator terminal device 10, information on a client who has requested storage of a plurality of containers, information on the cell storage device 22, and storage of a plurality of containers. A database 400 in which various information such as information is recorded, a communication control unit 410 that communicates with the administrator terminal device 10 and the cell storage terminal device 20, a data processing unit 420 that executes various processes, and a server device 40 A server management control unit 430 that controls each unit, a ROM / RAM 440 that is used to control each unit, and a timer 450 that is used to perform time management. Note that the above-described units are connected to each other by a bus B, and data transfer is performed between the components.

  The communication control unit 410 is a predetermined network interface, establishes a communication line with the administrator terminal device 10 or the cell storage terminal device 20, and exchanges various data with the administrator terminal device 10 or the cell storage terminal device 20. .

  For example, the communication control unit 410 receives information such as container IDs of a plurality of containers read by the recording medium reading device 11 from the administrator terminal device 10, and acquires information such as container IDs of the plurality of containers. In addition, the communication control unit 410 receives information such as the container ID read by the recording medium reading device 21 and assigned to the container to be stored in the cell storage device 22 from the cell storage terminal device 20, and the cell storage device The information such as the container ID assigned to the container to be stored in 22 is acquired. Furthermore, when the container is taken out from the cell storage device 22, the communication control unit 410 receives from the cell storage terminal device 20 information such as the container ID assigned to the container to be returned to the cell storage device 22. Then, information such as the container ID assigned to the container to be returned to the cell storage device 22 is acquired. In addition, the communication control unit 410 receives information such as information indicating that the cell is extracted from the container ID and the cell and cultured, from the cell storage terminal device 20, and indicates that the cell is extracted from the container ID and the container and cultured. Obtain information such as information. The communication control unit 410 according to the present embodiment constitutes, for example, a container identification information acquisition unit, a storage container identification information acquisition unit, a culture information acquisition unit, and the like according to the present invention.

  The database 400 includes, for example, an HDD (Hard Disk Drive) or the like, and includes a terminal device database (hereinafter abbreviated as “terminal device DB”) 401 and a requester database (hereinafter abbreviated as “requester DB”) 402. A cell storage device database (hereinafter abbreviated as “cell storage device DB”) 403 and a container database (hereinafter abbreviated as “container DB”) 404.

  The terminal device DB 401 is a database in which various information for managing information on each administrator terminal device 10 and each cell storage terminal device 20 for which the server device 40 provides various network services is recorded. For example, the terminal device DB 401 includes an administrator terminal device ID or cell storage terminal device ID corresponding to each administrator terminal device 10 or each cell storage terminal device 20, and each administrator terminal device ID or each cell storage terminal device ID. And the access authority of the administrator terminal device 10 or the cell storage terminal device 20 having each administrator terminal device ID or each cell storage terminal device ID are recorded in association with each other.

  The requester DB 402 is a database in which information of requesters who have requested storage of a plurality of containers is recorded. For example, in the client DB 402, client identification information (hereinafter referred to as “client ID”) corresponding to each client, client name information indicating the client name or name, and client location. And the contact information of the requester are recorded in association with each other.

The cell storage device DB 403 is a database in which a cell storage device ID assigned to the cell storage device 22 and various information for managing the cell storage device ID are recorded. For example, in the cell storage device DB403, as shown in FIG.
(1) a cell storage device ID;
(2) Information on the installation location of the cell storage device 22 assigned with the cell storage device ID;
(3) Cell storage environment condition information such as set temperature or measured temperature, set humidity or measured humidity, set CO ₂ concentration or measured CO ₂ concentration in the cell storage device 22 assigned with the cell storage device ID;
(4) availability information of the cell storage device 22 to which the cell storage device ID is assigned;
Are recorded in association with each other.

The container DB 404 is a database in which each container ID assigned to a plurality of containers requested to be stored by the client and various information for managing the container ID are recorded. For example, in the container DB 404, as shown in FIG.
(1) Container ID,
(2) Information on cells placed in a container given a container ID;
(3) Storage environment condition information of cells placed in a container given a container ID;
(4) a container group ID set for a container to which a container ID is assigned;
(5) The cell storage device ID assigned to the cell storage device 22 that is the storage destination of the container to which the container ID is assigned, that is, the cell storage device ID to which the container ID is assigned,
(6) Container storage history information indicating that the container is stored in the cell storage device 22 assigned to the container assigned with the container ID, or that the container has been returned;
Are recorded in association with each other.

  Note that the container storage history information includes time information when the container assigned with the container ID is stored in the cell storage device 22 assigned to the container, and time information returned to the cell storage device 22. However, the container storage history information is only information indicating that the container is stored in the cell storage device 22 assigned to the container assigned with the container ID, or that the container has been returned. Alternatively, information indicating that the container is stored in the cell storage device 22 assigned to the container assigned with the container ID, or the information and the container assigned with the container ID are assigned to the container. Only the time information stored in the stored cell storage device 22 may be used.

  The data processing unit 420 executes various types of data processing according to the application recorded in the ROM / RAM 440. In particular, the data processing unit 420 includes a setting unit 421, a recording unit 422, an allocation unit 423, and a determination unit 424. For example, the setting unit 421, the recording unit 422, the allocation unit 423, and the determination unit 424 of the present embodiment constitute an allocation unit, a recording control unit, a determination unit, and a setting unit of the present invention, respectively.

  When the communication control unit 410 receives information such as container IDs and cell storage environment conditions of a plurality of containers from the administrator terminal device 10, the setting unit 421 sets container group IDs for the container IDs of the plurality of containers. In addition, the setting unit 421 receives information including the container group ID set for the container IDs of the plurality of containers, and the information such as the container IDs of the plurality of containers and the cell storage environment conditions via the communication control unit 410. It transmits to the administrator terminal device 10 which transmitted.

  In addition, the setting unit 421 receives and acquires information such as the container ID, information indicating that the cell is extracted from the container and cultured, and information on the storage environment condition of the culture from the cell storage terminal device 20. Then, a new container ID is set for a new container containing the cell culture.

  When the recording unit 422 records each container ID, container group ID, and cell storage environment condition information in association with each other in the container DB 404, the allocation unit 423 determines the cell storage device 22 that distributes and stores a plurality of containers. A plurality of container IDs having the same container group ID are assigned to two or more cell storage device IDs.

  The allocation of the plurality of container IDs set with the same container group ID to the two or more cell storage device IDs in the allocation unit 423 is not particularly limited. For example, a plurality of containers can be stored. The number of cell storage device IDs assigned to the possible cell storage device 22 may be assigned by assigning container IDs of a plurality of containers. More specifically, when there are five containers containing the same type of cells and there are three cell storage devices 22, the container ID001, container ID002, container ID003, container ID004, and container ID005 are not used. Three are selected for the operation, and the container IDs are allocated and assigned to the cell storage device ID001, the cell storage device ID002, and the cell storage device ID003 in the order of selection. If the container ID 003 and the container ID 005 remain, a dummy container ID 006 is added to create three container ID groups, and the container IDs are selected in the order of selection by selecting three randomly. Allocating and assigning a cell storage device ID other than the dummy container ID 006.

  In addition, for example, one set of three cell storage device IDs such as cell storage device ID001 → cell storage device ID002 → cell storage device ID003 → cell storage device ID003 → cell storage device ID001 → cell storage device ID002 →. Then, a character string that is randomly repeated may be generated, and the order of cell storage device IDs to which container IDs are assigned may be set in advance, and container IDs may be assigned in order from the top.

In addition, the assigning unit 423 receives from the administrator terminal device 10 via the communication control unit 410 before performing processing for assigning a plurality of container IDs in which the same container group ID is set to two or more cell storage device IDs. Based on the cell storage environment condition information of the plurality of containers and the availability information of the cell storage device 22 recorded in the cell storage device DB 403, a plurality of container IDs having the same container group ID can be assigned. Extract cell storage device ID. For example, the information stored in the cell storage device DB 403 is read, the cell storage environment conditions in the cell storage environment condition information of the plurality of containers received from the administrator terminal device 10 are all satisfied, and the cell storage device 22 has an empty space. A cell storage device ID is extracted. More specifically, the cell storage environment conditions of the plurality of containers are temperature: −90 to −70 degrees, humidity: no request, CO ₂ concentration: no request, and the cell storage device 22 as shown in FIG. Is provided, the assigning unit 423 extracts 001, 005, 006, 007, 008, etc. as cell storage device IDs to which a plurality of container IDs having the same container group ID can be assigned. . Further, when the cell storage environmental conditions of the plurality of containers are temperature: 80 degrees, humidity: 100%, CO ₂ concentration: 0.05%, and a cell storage device 22 as shown in FIG. 5 is provided. In other words, the assigning unit 423 extracts 001, 006, 008, and the like as cell storage device IDs to which a plurality of container IDs set with the same container group ID can be assigned.

  Then, the assignment unit 423 determines whether there are two or more extracted cell storage device IDs. When determining that there are two or more cell storage device IDs, the assigning unit 423 assigns a plurality of container IDs in which the same container group ID is set to the two or more extracted cell storage device IDs. On the other hand, if the allocation unit 423 determines that there are not two or more cell storage device IDs, the allocation unit 423 notifies the administrator terminal device 10 via the communication control unit 410 that the containers cannot be distributed and stored. Notice.

  When the communication control unit 410 receives information such as the container ID and the cell storage device ID from the cell storage terminal device 20, the determination unit 424 reads information that associates the container ID recorded in the container DB 404 with the cell storage device ID. The cell storage device ID received from the cell storage terminal device 20, that is, the cell storage device ID assigned to the cell storage device 22 to store the container to which the container ID is assigned, or the container to which the container ID is assigned. It is determined whether or not the cell storage device ID assigned to the cell storage device 22 that is going to return is consistent with the cell storage device ID recorded in association with the container ID received from the cell storage terminal device 20.

  If it is determined that they match, the determination unit 424 notifies the cell storage terminal device 20 that has transmitted the information such as the container ID and the cell storage device ID that there is no problem in the storage location of the container via the communication control unit 410. To do. On the other hand, if the determination unit 424 determines that they do not match, the cell storage terminal device 20 that has transmitted the information such as the container ID and the cell storage device ID has a problem with the storage location of the container via the communication control unit 410. Notify that there is.

  The recording unit 422 includes a plurality of containers received by the communication control unit 410 from the administrator terminal device 10 and information such as cell storage environment conditions, and a container set by the setting unit 421 for the container IDs of the plurality of containers. Based on the group ID, each container ID, container group ID, and cell storage environment condition information are associated and recorded in the container DB 404.

  The recording unit 422 records the container ID and the cell storage device ID to which the assigning unit 423 assigns the container ID in the container DB 404 in association with each other. In addition, the recording unit 422 installs the cell storage device 22 recorded in association with the cell storage device ID based on the cell storage device IDs respectively associated with the plurality of container IDs in which the same container group ID is set. Is read from the cell storage device DB403. Then, the recording unit 422 provides the administrator with an installation location of the cell storage device 22 that stores each of the plurality of containers, so that each container ID and the cell storage device 22 that stores the container to which the container ID is assigned are stored. Information relating the installation location information is transmitted via the communication control unit 410 to the administrator terminal device 10 that has transmitted information such as container IDs and cell storage environmental conditions of a plurality of containers.

  When the recording unit 422 determines that the determination unit 424 matches, the recording unit 424 stores the container assigned with the container ID in the cell storage device 22 provided with the cell storage device ID recorded in association with the container ID. The container storage history information indicating that it has been returned or returned is recorded.

  When the setting unit 421 sets a new container ID for the new container in which the cell culture is put, the recording unit 422 displays the new container ID set by the setting unit 421 and the culture storage environment condition information. Correlate and record in the container DB 404. In addition, the recording unit 422 associates the container ID given to the container from which the cell is taken out, that is, the container ID received from the cell storage terminal device 20 by the communication control unit 410 with the new container ID in the container DB 404. Record. Then, the recording unit 422 takes out information such as the new container ID set in the new container containing the cell culture and the storage environment condition information of the culture from the container ID and the container. It transmits to the cell storage terminal device 20 which transmitted the information which shows having performed, and information, such as storage environment condition information of a culture, via the communication control part 410. FIG.

  The server management control unit 430 is mainly configured by a central processing unit (CPU), and integrally controls each unit of the server device 40 by executing a program. Specifically, the server management control unit 430 performs login processing for each administrator or each worker based on a login request from the administrator terminal device 10 operated by the administrator or the cell storage terminal device 20 operated by the operator. , And other various controls.

  Various programs necessary for driving the server device 40 are recorded in the ROM / RAM 440. In addition, various applications executed by the data processing unit 420 and the server management control unit 430 are recorded in the ROM / RAM 440. The ROM / RAM 440 is used as a work area during execution of each program.

  The timer 450 is used for managing the time required when the recording unit 422 records the container storage history information.

[5] System Operation Next, specific processing executed in the cell storage system S of the present embodiment will be described with reference to FIGS. 7 to 9 are flowcharts showing processing executed in the cell storage system S in order to determine two or more cell storage devices 22 each storing a plurality of containers requested by the client. FIGS. 10 and 11 are flowcharts showing processing executed in the cell storage system S when the container is stored in the cell storage device 22 or returned. FIGS. 12 and 13 are flowcharts showing processes executed in the cell storage system S to manage the culture of cells taken out of the container.

  More specifically, FIG. 7 is a flowchart showing a process for assigning a plurality of container IDs set with the same container group ID to two or more cell storage devices 22 executed in the cell storage system S. FIG. 8 is a flowchart showing a process for issuing a recording medium executed in the cell storage system S, and FIG. 9 is a flowchart showing a process for outputting image data executed in the cell storage system S. It is.

  FIG. 10 is a flowchart showing a process executed in the cell storage system S for determining whether or not there is a problem in the container storage location. FIG. 11 is an image executed in the cell storage system S. It is a flowchart which shows the process for outputting data.

  FIG. 12 is a flowchart showing a process for setting a new container ID in a new container in which a cell culture is put, which is executed in the cell storage system S. FIG. It is a flowchart which shows the process for issuing the recording medium performed.

[5.1] Process for Determining Cell Storage Device First, in the present embodiment using FIG. 7 to FIG. 9, two or more cell storage devices 22 each storing a plurality of containers requested by a client are provided. Processing to be executed in the cell storage system S for determination will be described. In this operation, the communication control unit 110 of the administrator terminal device 10 waits for the administrator to read the information on the recording medium provided in the container that has been requested to be stored by the client by the recording medium reader 11. Suppose you are. This process is performed when the administrator receives a plurality of containers requested to be stored by the client.

  In this state, the communication control unit 110 reads information such as each container ID and cell storage environment condition information of the plurality of containers recorded on the recording medium provided in the container by the recording medium reading device 11 (step S100). Information such as container IDs and cell storage environmental condition information of a plurality of containers is transmitted to the server device 40 (step S101). Then, the administrator terminal management control unit 130 shifts to a state of waiting for data reception from the server device 40.

  Next, in the server device 40, when the setting unit 421 receives information such as container IDs and cell storage environment conditions of a plurality of containers from the administrator terminal device 10 via the communication control unit 410 (step S200), the plurality of containers A container group ID is set for the container ID (step S201). Then, the setting unit 421 receives information including the container group IDs set for the container IDs of the plurality of containers via the communication control unit 410, such as the container IDs of the plurality of containers and the cell storage environment condition information. Is transmitted to the administrator terminal device 10 that has transmitted (step S202).

  In addition, the recording unit 422 receives information such as container IDs and cell storage environment conditions of a plurality of containers received from the administrator terminal device 10 via the communication control unit 410, and the setting unit 421 corresponds to the container IDs of the plurality of containers. Each container ID, container group ID, and cell storage environment condition information are associated with each other and recorded in the container DB 404 based on the container group ID set in step S203.

  The assigning unit 423 reads cell storage environmental condition information recorded in association with a plurality of container IDs for which the same container group ID is set in the container DB 404, and also reads information recorded in the cell storage device DB 403. A cell storage device ID that satisfies all the cell storage environment conditions in the storage environment condition information and that is free in the cell storage device 22 is extracted (step S204).

  Next, the assigning unit 423 determines whether there are two or more extracted cell storage device IDs (step S205). If the allocation unit 423 determines that there are two or more cell storage device IDs (step S205; Yes), the allocation unit 423 assigns a plurality of container IDs in which the same container group ID is set to the extracted two or more cell storage device IDs. Assign (step S206). Then, the recording unit 422 associates the cell storage device ID to which the assigning unit 423 assigns each container ID with a plurality of container IDs to which the same container group ID is set, and records them in the container DB 404 (step S207).

  In addition, the recording unit 422 installs the cell storage device 22 recorded in association with the cell storage device ID based on the cell storage device IDs respectively associated with the plurality of container IDs in which the same container group ID is set. Is read from the cell storage device DB 403, and a plurality of container IDs set with the same container group ID are associated with information on the installation location of the cell storage device 22 that stores the containers assigned with the respective container IDs. Information is transmitted via the communication control unit 410 to the administrator terminal device 10 that has transmitted information such as container IDs and cell storage environmental conditions of a plurality of containers (step S208), and the server management control unit 430 performs this operation. Terminate.

  On the other hand, if the allocation unit 423 determines that there are no two or more cell storage device IDs (step S205; No), the communication control unit 410 notifies that the containers cannot be distributed and stored. The administrator terminal device 10 is notified (step S209), and the server management control unit 430 ends this operation.

  In the administrator terminal device 10, when the communication control unit 110 receives information such as the container group ID set for the container IDs of the plurality of containers transmitted by the setting unit 421 in (step S202) (step S110). ), The recording medium issue processing unit 140 instructs the recording medium issuing device 12 to issue a recording medium in which information such as a container group ID is recorded for a plurality of container IDs in which the same container group is set ( In step S111), the administrator terminal management control unit 130 ends this operation.

  Further, in the administrator terminal device 10, the communication control unit 110 includes a plurality of container IDs set with the same container group ID transmitted by the recording unit 422 in (Step S208), and containers to which each container ID is assigned. Information relating to the location information of the cell storage device 22 to be stored, or a notification from the server device 40 that the containers transmitted by the assigning unit 423 in (Step S209) cannot be distributed and stored. When receiving (step S120), the display control unit 161 generates image data necessary to display the information (step S121). Then, the display control unit 161 outputs the image data to the display unit 160 (step S122), and the administrator terminal management control unit 130 ends this operation.

  In the present embodiment, the server device 40 performs the transmission processing of (Step S202) and (Step S208) separately, but after performing the recording processing of (Step S207) (Step S202). And (step S208) may be performed together.

[5.2] Processing executed when storing or returning the container Next, in this embodiment with reference to FIGS. 10 and 11, cell storage when the container is stored in the cell storage device 22 or returned. Processing executed in the system S will be described. In this operation, it is assumed that the communication control unit 210 of the cell storage terminal device 20 waits for the operator to read the recording medium provided in the container with the recording medium reading device 21. This process is performed when the transported container is stored in the cell storage device 22 or when the container taken out from the cell storage device 22 is returned to the cell storage device 22.

  In this state, when the communication control unit 210 reads information such as the container ID and the cell storage device ID recorded on the recording medium provided in the container with the recording medium reading device 21 (step S300), the container ID and the cell storage are stored. Information such as the device ID is transmitted to the server device 40 (step S301). And the cell storage terminal management control part 230 transfers to the state which waits for the data reception from the server apparatus 40. FIG.

  Next, in the server device 40, when the determination unit 424 receives information such as the container ID and the cell storage device ID from the cell storage terminal device 20 via the communication control unit 410 (step S210), the container recorded in the container DB 404 The information relating the ID and the cell storage device ID is read, and the cell storage device ID received from the cell storage terminal device 20 matches the cell storage device ID recorded in association with the container ID received from the cell storage terminal device 20. It is determined whether or not to perform (step S211).

  If the determination unit 424 determines that they match (step S211; Yes), the container storage location is sent to the cell storage terminal device 20 that has transmitted information such as the container ID and the cell storage device ID via the communication control unit 410. Is notified that there is no problem (step S212). Then, the recording unit 422 stores that the container assigned with the container ID is stored in the cell storage device 22 provided with the cell storage device ID recorded in association with the container ID or returned. The container storage history information indicating this is recorded (step S213), and the server management control unit 430 ends this operation.

  On the other hand, if the determination unit 424 determines that they do not match (step S211; No), the container is sent to the cell storage terminal device 20 that has transmitted information such as the container ID and the cell storage device ID via the communication control unit 410. Is notified that there is a problem in the storage location (step S214), and the server management control unit 430 ends this operation.

  In the cell storage terminal device 20, the communication control unit 210 notifies that there is no problem in the storage location of the container transmitted by the determination unit 424 in (Step S212) or transmitted by the determination unit 424 in (Step S214). Upon receiving a notification that there is a problem in the container storage location (step S310), the display control unit 261 generates image data necessary to display the notification information (step S311). Then, the display control unit 261 outputs the image data to the display unit 260 (Step S312), and the cell storage terminal management control unit 230 ends this operation.

[5.3] Process for Managing Culture Next, in the present embodiment with reference to FIG. 12 and FIG. 13, the process is performed in the cell storage system S to manage the culture of cells taken out from the container. Processing will be described. In this operation, the communication control unit 210 of the cell storage terminal device 20 receives information indicating that the cell storage terminal management control unit 230 has taken out and cultured the cells from the container by an input operation using the operator's operation unit 270, and It is assumed that input of culture storage environment condition information is detected, and that the operator is waiting for the recording medium reading device 21 to read the recording medium provided in the container. This process is performed when the container is taken out from the cell storage device 22 and the cells are taken out from the container and cultured.

  In this state, the communication control unit 210 includes information indicating that the cell storage terminal management control unit 230 has taken out and cultured the cells from the container by an input operation using the operator's operation unit 270, and a culture storage environment. When the input of the condition information is detected (step S320) and information such as the container ID recorded on the recording medium provided in the container is read by the recording medium reader 21 (step S321), the cell is taken out from the container ID and the container. Information indicating that the cells have been cultured, and information such as storage environment condition information of the culture are transmitted to the server device 40 (step S322). And the cell storage terminal management control part 230 transfers to the state which waits for the data reception from the server apparatus 40. FIG.

  Next, in the server device 40, the setting unit 421 includes the container ID from the cell storage terminal device 20 via the communication control unit 410, information indicating that the cells have been taken out from the container and cultured, storage environment condition information of the culture, and the like. Is received and acquired (step S220), a new container ID is set for the new container containing the cell culture (step S221). The recording unit 422 records the new container ID set by the setting unit 421 and the storage environment condition information of the culture in the container DB 404 and associates the container ID with the new container ID. It records in DB404 (step S222).

  Next, the recording unit 422 takes out information such as the new container ID set in the new container containing the cell culture and the storage environment condition information of the culture from the container ID and the container, and cultures them. The information indicating that it has been performed and the information such as the storage environment condition information of the culture are transmitted to the cell storage terminal device 20 via the communication control unit 410 (step S223), and the server management control unit 430 performs the main operation. End.

  Next, in the cell storage terminal device 20, the communication control unit 210 sends information such as a new container ID set in the new container containing the cell culture and storage environment condition information of the culture to the server device 40. (Step S330), the recording medium issue processing unit 240 records information such as a new container ID set in the new container containing the cell culture and storage environment condition information of the culture. The recording medium issuing device 23 is instructed to issue the recording medium (step S331), and the cell storage terminal management control unit 230 ends this operation.

  In the present embodiment, the process of (Step S321) is performed after the process of (Step S320), but these processes may be reversed.

[6] Modification [6.1] Modification 1
In the above embodiment, each DB is provided in the server device 40 for management and control. However, the computer systems that manage and control each DB may be operated by separate computer systems. Good. In addition, a computer system serving as a management and control entity for each DB may be installed outside via the network 20.

[6.2] Modification 2
In the above embodiment, the cell storage terminal device 20 is installed around the cell storage device 22, but the cell storage device 22 may be provided with the function of the cell storage terminal device 20.

[6.3] Modification 3
In the above embodiment, the case where the recording medium is a label on which a code such as a barcode, a two-dimensional barcode, or an alphanumeric character code is recorded has been described. However, the recording medium is a barcode, a two-dimensional barcode, an alphanumeric A rewritable label or the like such as a character code may be used. In addition, the recording medium may be, for example, an IC tag including an IC chip such as RAM, EEPROM, UV-EPROM, and an information processing device (CPU) that accesses the recording medium.

  When the recording medium as described above is used, the recording medium readers 11 and 21 are preferably a code reader / writer or an IC tag reader / writer that can rewrite information recorded on the recording medium. Thereby, it is not necessary to install the recording medium issuing devices 12 and 23, and the recording medium can be temporarily used as individual databases when the server device 40 is down. The information recorded on the recording medium includes the container ID, the requester ID, the cell storage environment condition information, the container group ID, the assigned cell storage device ID, the location information of the cell storage device ID, Container storage history information and the like can be listed, and these pieces of information are recorded in association with each other.

[6.4] Modification 4
In the above embodiment, the display control unit 161 generates image data necessary for displaying an image indicating a notification that the containers cannot be distributed and stored on the display unit 160, and the display control unit 161 261 generates image data necessary to display an image indicating a notification that there is a problem in the storage location of the container on the display unit 260, but the administrator terminal device 10 and the cell storage terminal device 20 Instead of displaying an image, a warning sound may be generated.

[6.5] Modification 5
In the above-described embodiment, when the communication control unit 410 receives information such as container IDs and cell storage environmental conditions of a plurality of containers from the administrator terminal device 10, the setting unit 421 stores containers for a plurality of container IDs. Although the group ID is set, the determination unit 424 determines whether or not the cell storage environment condition information of the plurality of containers matches, and if it is determined that they match, the setting unit 421 determines the container ID of the plurality of containers. A container group ID may be set for. By performing the determination process in this way, it is possible to more safely store a plurality of containers containing the same type of cells. When the determination unit 424 determines that they do not match, the administrator terminal device 10 is notified that a plurality of containers cannot be distributedly managed, and an image indicating the notification is displayed on the display unit 260. Also good.

[6.6] Modification 6
In the above embodiment, the setting unit 421 sets the container group ID for the container IDs of a plurality of containers. However, the container group ID is set on the recording medium provided in each of the plurality of containers in which the same type of cells are placed. It may be recorded in advance.

[6.7] Modification 7
In the above embodiment, one cell storage device 22 is provided around one cell storage terminal device 20 to manage the container. However, a plurality of cells are provided around one cell storage terminal device 20. A storage device 22 may be provided to manage the container.

[6.8] Modification 8
In the above embodiment, the administrator terminal device 10 and the server device 40 are provided in the cell storage system S, respectively, but the administrator terminal device 10 is provided with a part or all of the functions of the server device 40 and the database. The administrator terminal device 10 may cause part or all of the processing performed by the server device 40 to be performed.

[6.9] Modification 9
In the above embodiment, the cell storage terminal management control unit 230 detects information indicating that the cells have been taken out from the container and cultured, and the communication control unit 210 transmits the information to the server device 40. The cell storage terminal management control unit 230 may detect information indicating that some or all of the cells have been extracted from the container and cultured, and the communication control unit 210 may transmit the information to the server device 40. Accordingly, the recording unit 422 of the server device 40 transmits from the cell storage terminal device 20 when receiving and acquiring information indicating that all cells have been extracted from the container and cultured via the communication control unit 410. Information indicating that no cell exists may be recorded in the container storage history information recorded in the container DB 404 in association with the container ID.

  As described above, in the cell storage system S of the present embodiment, a plurality of containers containing the same type of cells requested to be stored by the client are installed in different facilities, different rooms, or the same room. The above cell storage device 22, in particular, two or more cell storage devices that satisfy the cell storage environment condition and can store the container and can be distributed, and each cell storage device is allocated to a plurality of containers. A plurality of containers can be properly stored and managed in 22.

  Therefore, in the cell storage system S of the present embodiment, the cell storage device 22 in which the same type of cells are stored can be managed, and all the same type of cells can be stored even if an accident such as a natural disaster or infrastructure disconnection occurs. The risk of losing can be reduced.

  In the cell storage system S of the present embodiment, when the allocating unit 423 determines that there are not two or more cell storage devices 22 that satisfy the cell storage environment condition and can store the container, Administrators can be notified that multiple containers containing the same type of cells cannot be distributed and stored, so the administrator can manage the distribution at the time of receiving multiple containers containing the same type of cells. I can understand what I can't do.

  Furthermore, in the cell storage system S of the present embodiment, even when the container taken out from the cell storage device 22 is to be returned to the cell storage device 22, the determination unit 424 is to return the cell storage device 22 to be returned. Therefore, it is possible to correctly return the container taken out from the cell storage device 22 to the original location.

  In the cell storage system S of the present embodiment, when storing the container in the cell storage device 22 or when returning the container taken out from the cell storage device 22 to the cell storage device 22, a message to that effect is stored in the database. Since the container storage history information is recorded in 400, the administrator and the operator can confirm that a plurality of containers are distributed and stored, and in which cell storage device 22 the container is stored, and It is possible to know when it was stored or when it was returned.

  In addition to the above, in the cell storage system S of the present embodiment, the recording unit 422 includes a container ID of a container in which cells are stored, and a new container ID of a new container in which cultures of the cells are stored. The administrator records the cell requested to be stored by the client and the culture of the cell, for example, the differentiated cell of the cell, the subcultured cell of the cell, the tissue culture of the cell, etc. Can be managed together.

S ... Cell storage system BS ... Base station B ... Bus 10 ... Administrator terminal device 11 ... Recording medium reader 12 ... Recording medium issuing device 20 ... Cell storage terminal device 21 ... Recording medium reader 22 ... Cell storage device 23 ... Recording Medium issue device 30 ... Network 40 ... Server device 110 ... Communication control unit 130 ... Administrator terminal management control unit 140 ... Recording medium issue processing unit 150 ... ROM / RAM
160 ... display unit 161 ... display control unit 170 ... operation unit 210 ... communication control unit 230 ... cell storage terminal management control unit 240 ... recording medium issue processing unit 250 ... ROM / RAM
260 ... display unit 261 ... display control unit 270 ... operation unit 400 ... database 401 ... terminal device DB
402 ... Client DB
403 ... Cell storage device DB
404 ... Container DB
410 ... Communication control unit 420 ... Data processing unit 421 ... Setting unit 422 ... Recording unit 423 ... Allocation unit 424 ... Determination unit 430 ... Server management control unit 440 ... ROM / RAM
450… Timer

Claims (11)

A cell storage system for storing a plurality of containers containing the same type of cells dispersed in two or more cell storage devices,
Container identification information acquisition means for acquiring container identification information assigned to each of the plurality of containers;
Assigning means for assigning the container identification information to the cell storage device identification information assigned to each of the two or more cell storage devices;
Recording control means for associating the container identification information with the cell storage device identification information to which the container identification information is assigned, and recording it in a database;
Storage container identification information acquisition means for acquiring the container identification information given to the container to be stored in the cell storage device;
Based on the information recorded in the database in association with the recording control means, the cell storage device identification information given to the cell storage device that intends to store the container to which the container identification information is given is the storage container identification information. A determination unit that determines whether or not the cell storage device identification information recorded in association with the container identification information acquired by the acquisition unit matches;
A cell storage system comprising: The cell storage system according to claim 1,
The allocating means includes two or more cells to which the plurality of containers can be allocated based on storage environment condition information of cells placed in the container to which the container identification information is assigned and availability information of the cell storage device A cell storage system that extracts a storage device and assigns the plurality of containers to two or more extracted cell storage devices. The cell storage system according to claim 1 or 2,
The allocating means includes a cell storage device capable of allocating the plurality of containers based on storage environment condition information of cells placed in the container to which the container identification information is assigned and availability information of the cell storage device. It is determined whether there are two or more extracted cell storage devices, and if it is determined that there are not two or more cell storage devices, the plurality of containers containing the same type of cells are dispersed. A cell storage system that notifies you that it cannot be stored. The cell storage system according to any one of claims 1 to 3,
When the container is removed from the cell storage device,
The storage container identification information acquisition means acquires the container identification information given to the container to be returned to the cell storage device,
The determination means, based on the information recorded in the database in association with the recording control means, the cell storage device identification information attached to the cell storage device to return the container to which the container identification information is attached, The cell storage system which determines whether it matches with the said cell storage apparatus identification information recorded in association with the said container identification information which the said storage container identification information acquisition means acquired. In the cell storage system according to any one of claims 1 to 4,
The determination means associates the cell storage device identification information given to the cell storage device that intends to store the container to which the container identification information is given with the container identification information acquired by the storage container identification information acquisition means. When it is determined that it matches the recorded cell storage device identification information, the container to which the container identification information is assigned is the cell to which the cell storage device identification information is recorded in association with the container identification information. A cell storage system that records information indicating that it is stored in a storage device in the database. In the cell storage system according to any one of claims 1 to 5,
Culture information acquisition means for acquiring the container identification information given to the container, and information indicating that the cells are taken out from the container and cultured;
When the culture information acquisition means acquires the container identification information given to the container and information indicating that the cells have been taken out from the container and cultured, the container is placed in a new container containing the cell culture. A setting means for setting identification information;
The cell storage system, wherein the recording control unit associates and records the container identification information given to the container and the container identification information set to the new container in the database. A cell storage system for dispersing and storing a plurality of containers containing the same type of cells in two or more cell storage devices,
Container identification information acquisition means for acquiring container identification information assigned to each of the plurality of containers;
An assigning means for assigning the container identification information to the cell storage device identification information assigned to each of the two or more cell storage devices;
Recording control means for associating the container identification information with the cell storage device identification information to which the container identification information is assigned and recording it in a database;
A storage container identification information acquisition means for acquiring the container identification information given to the container to be stored in the cell storage device; and
Based on the information recorded in the database in association with the recording control means, the cell storage device identification information given to the cell storage device that intends to store the container to which the container identification information is given is the storage container identification information. A determination unit that determines whether or not the cell storage device identification information recorded in association with the container identification information acquired by the acquisition unit is identical;
A program characterized by functioning as A cell storage system for storing a plurality of containers containing the same type of cells dispersed in two or more cell storage devices,
A recording medium reader for reading container identification information given to the container from a recording medium provided in the container to be stored in the cell storage device;
A storage management device that manages a storage destination of a cell storage device that stores each container based on the container identification information given to each of the plurality of containers;
With
The storage management device is
Container identification information acquisition means for acquiring the container identification information;
Assigning means for assigning the container identification information to the cell storage device identification information assigned to each of the two or more cell storage devices;
Recording control means for associating the container identification information with the cell storage device identification information to which the container identification information is assigned, and recording it in a database;
Storage container identification information acquisition means for acquiring the container identification information read by the recording medium reader from the recording medium provided in the container to be stored in the cell storage device;
Based on the information recorded in the database in association with the recording control means, the cell storage device identification information given to the cell storage device that intends to store the container to which the container identification information is given is the storage container identification information. A determination unit that determines whether or not the cell storage device identification information recorded in association with the container identification information acquired by the acquisition unit matches;
A cell storage system comprising: The cell storage system according to claim 8,
The cell storage system, wherein the recording medium has container group identification information given to the plurality of containers in which cells of the same type are placed. The cell storage system according to claim 8 or 9,
The cell storage system, wherein the recording medium is a recording medium capable of rewriting information on the container or cells contained in the container. A cell storage method for dispersing and storing cells using a cell storage system for dispersing and storing a plurality of containers containing the same type of cells in two or more cell storage devices,
Obtaining container identification information assigned to each of the plurality of containers;
Assigning the container identification information to cell storage device identification information assigned to each of the two or more cell storage devices;
Correlating the container identification information with the cell storage device identification information to which the container identification information is assigned, and recording it in a database;
Obtaining the container identification information given to the container to be stored in the cell storage device;
Based on the information recorded by the recording control means in association with the database, the cell storage device identification information assigned to the cell storage device that is intended to store the container to which the container identification information is assigned is stored in the cell storage device. Determining whether or not the cell storage device identification information recorded in association with the container identification information given to the container to be matched,
A cell storage method comprising:

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