JP2005285142A - Medical care self-cell delivery support system, medical care self-cell delivery support financial system, and their methods - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a system in which in case of emergency a cure is brought effectively by infusing self-cells into the body quickly. <P>SOLUTION: A medical care self-cell delivery support system 100 preserves medical care self-cells collected from a member in a preservation means 34. When a delivery request receiving means 21 of the system receives from a member a self-cell delivery request including ID information and location information on the member, the system searches for the member information according to the ID information, and outputs the member information and the location information so as to deliver the self-cells from the preserving storage facility at the deliverer to the destination facility. If a plurality of preservation means exist at geographically different locations, the preservation means from which it takes the shortest time for delivery is selected based on the location information included in the delivery request. By using an ID information storage means 11 for sending the ID information manually or automatically, a delivery request is issued with an easy operation or automatically while monitoring health data. <P>COPYRIGHT: (C)2006,JPO&NCIPI

Description

  The present invention relates to a therapeutic self-cell delivery support system, and more specifically, stores therapeutic self-cells collected from the person, and sends the therapeutic self-cells for treatment in response to a delivery request from the person. The present invention relates to a therapeutic self-cell delivery support system that supports delivery from a storage facility to a person.

  In recent years, regenerative medicine has been in the spotlight. In regenerative medicine, in response to body damage that the human body's regenerative capacity does not reach, surgically joining organs etc. that have regenerated their own cells by artificial growth to the damaged site, it is possible to He is starting to heal. In regenerative medicine, a large amount of preparatory work is required before the actual treatment, so that not only medical technology but also a system that supports the treatment becomes very important.

  As a conventional support system related to regenerative medicine, cells are collected in advance, information on cells can be browsed according to a request from a client, and cells are delivered to a plurality of companies, where cell proliferation, There is a technology related to a cell bank system and a cell freezing / thawing method that enables differentiation or order-made drugs and cosmetics to be manufactured (see, for example, Patent Document 1). In the technology, the cell storage means for storing the cells collected from the client, and a memory storing information on the stored cells, the cells stored via the Internet and The gene information can be viewed at any time. Then, according to instructions from the client, the cells can be transported to a tissue culture company to proliferate and differentiate, and can also be transported to a medicine / cosmetics manufacturing company to produce homemade medicines and cosmetics.

  However, this technology is based on transporting autologous cells to pharmaceutical / cosmetic manufacturing companies, etc. in order to proliferate and differentiate the autologous cells according to the purpose when the autologous cells are stored. Since it takes a considerable number of days to grow and differentiate in the company after transportation, it is extremely applicable to regenerative medicine that is effective for emergency disorders such as sudden illnesses and accidents. Have difficulty. In addition, the self cells used there are gene information acquisition, drug sensitivity test data acquisition, extraction of components such as proteins from proliferated self cells, transplantation treatment, totipotent ES cells (embryonic stem cells) Although it is intended for storage, it does not disclose anything that exhibits a therapeutic effect by rapid in vivo administration for urgent disorders. Moreover, when actually implementing such a method, it is essential to construct a practical system operation method that includes a reduction in the financial burden on the user. The problem is not even recognized.

JP 2002-27983 A

  As mentioned above, there is no system that supports regenerative medicine using autologous cells that exert therapeutic effects by rapid in vivo administration for urgent disorders. The failure to do so has not been resolved. Specifically, the following problems exist. By transmitting the user's ID information and position information by a simple operation, a delivery request for delivering the therapeutic self-cells from the storage facility serving as the delivery source to the treatment facility serving as the delivery destination is issued, and the delivery means accordingly It is necessary to send a delivery instruction to the transportation system. In that case, when there are a plurality of storage facilities and treatment facilities, it is necessary to select an appropriate one from them. In selecting a storage facility, it is necessary to minimize the time to the delivery destination. The delivery request needs to be able to be issued automatically while preventing malfunctions in case the patient's consciousness level decreases or the motor / sensory ability is damaged. The user's position information included in the delivery request needs to be able to automatically acquire an accurate position. It is necessary to make it possible for a user whose consciousness level or the like has been lowered to start treatment with therapeutic self-cells after confirming that the other person is the user. It is necessary to obtain the user's prior agreement on treatment, and if there is not at the time of treatment, it is necessary to obtain agreement from the parties concerned. It is necessary to provide an operation method that can perform system operation and emergency treatment without imposing a heavy burden on the user in terms of cost. Such a management method should preferably be a combination of a membership system and insurance. When insurance is irresponsible, it is necessary to notify the user or related parties to the effect and inform them in advance that the insurance money will not be paid, and to provide an early opportunity to prepare expenses. There is. It is necessary to notify the user or related parties of the progress of the process in the system, that is, the progress of the treatment support work in real time via a network or the like. Also, it is necessary to ensure that the system can be activated by a delivery request.

  Conventionally, however, there has been no system for solving the above-described problems. The present invention has been made in view of the above problems, and stores the therapeutic self-cells collected from the person, and stores the therapeutic self-cells for treatment in response to a delivery request from the person. It provides a system that supports delivery from equipment to the person.

The solution of the above-described problem is achieved by the present invention having the following features.
The invention according to claim 1 is used for treatment for in vivo damage site regeneration treatment by in vivo administration to a member who has been collected from the body of the member and grown to at least the amount necessary for treatment after the collection. Storage means for distinguishing and storing autologous cells for each member, ID information uniquely corresponding to the member storing the therapeutic self-cells in the storage means, and member information of the member including at least a member name Member information storage means which is made to function by a computer and stores the ID information of the member who needs delivery to the delivery destination of the therapeutic self-cell for treatment and the location information of the member A delivery request receiving means operable by a computer for receiving a request via a communication network; and a delivery request received by the delivery request receiving means. The member information retrieval means for retrieving the member information of the member from the member information storage means based on the ID information to be operated, and the member for outputting information in association with the storage means; And delivery request output means for outputting the member information searched by the information search means and the position information of the member.

  In addition to the features of the invention described in claim 1, the invention described in claim 2 includes a plurality of the storage means and the delivery request output means at geographically different positions, and is received by the delivery request receiving means. Based on the location information of the member included in the delivered delivery request, an appropriate delivery destination to which the member should receive treatment is identified from the locations including a plurality of pre-registered treatment facilities, and the plurality of storage means A delivery source specifying means that is made to function by a computer, specifying an appropriate storage means as a delivery source, member information at least including a member name searched by the member information search means, and the specified delivery destination A function for sending a delivery destination information to a delivery request output means associated with a delivery source storage means specified by the delivery source specifying means. Further comprising a distribution request transferring means, and said distribution request output means, transmitted by the delivery request transfer means, and outputs the member information and the shipping information, and wherein the.

  According to a third aspect of the present invention, in addition to the features of the second aspect, the storage means specified by the delivery source specifying means as the delivery source has the shortest delivery time to the specified delivery destination. 3. The therapeutic self-cell delivery support system according to claim 2, which is a storage means located in a geographical position.

  In addition to the features of the invention described in any one of claims 1 to 3, the invention described in claim 4 records the ID information of the member, and the ID information is transmitted via the communication network. It further comprises ID information storage means for transmitting to the delivery request receiving means.

  According to a fifth aspect of the invention, in addition to the feature of the fourth aspect of the invention, the ID information storage means transmits the ID information to the communication network in response to a manual operation by a member. And

  According to a sixth aspect of the invention, in addition to the features of the fourth aspect of the invention, the ID information storage means includes a physical rate including at least one of a heart rate, a respiratory cycle, an electrocardiogram pattern, a voice, and a body motion. Data is monitored, and when an abnormality is detected in the data, the ID information is transmitted to the communication network.

  According to a seventh aspect of the invention, in addition to the features of the sixth aspect of the invention, the ID information storage means once outputs an abnormality when an abnormality is detected in the physical condition data, and then The ID information is transmitted to the communication network on condition that a confirmation input is not made within a predetermined time.

  The invention described in claim 8 is characterized in that, in addition to the features of the invention described in any one of claims 1 to 7, the ID information storage means is connected to the communication network by radio. .

  The invention according to claim 9 is characterized in that, in addition to the features of the invention according to any one of claims 1 to 8, the location of the member is specified, and the specified location is determined by the member. It further has a position reporting means for transmitting to the delivery request receiving means via the communication network as position information.

  The invention described in claim 10 is characterized in that, in addition to the features of the invention described in claim 9, the location reporting means is connected to the communication network by radio.

  The invention described in claim 11 is characterized in that, in addition to the features of the invention described in claim 10, the location reporting means specifies the location of the member by GPS.

  The invention according to claim 12 is characterized in that, in addition to the features of the invention according to claim 10, the location reporting means identifies the location of the member by receiving radio waves from ground radio equipment. To do.

  According to a thirteenth aspect of the present invention, in addition to the features of the invention according to any one of the first to twelfth aspects, the member information stored in the member information storage means includes a face photo image, a fingerprint pattern, a vein Discrimination physical feature data including at least one of a pattern and an iris pattern is included.

  In addition to the features of the invention described in any one of claims 1 to 13, the invention described in claim 14 confirms through the communication network whether or not there is prior agreement from the member about the use of therapeutic autologous cells. The delivery request output means outputs the member information and location information of the member when there is a prior agreement of the member, and the prior confirmation of the member. If there is no agreement, the member information and the location information of the member are output on the condition that the agreement from the member or a related party of the predetermined member can be confirmed.

  According to a fifteenth aspect of the present invention, in addition to the features of the first aspect of the present invention, a delivery means for delivering the therapeutic self-cells based on the location information of the member is geographically distributed. And a delivery command means for specifying a plurality of delivery means existing at different positions and transmitting a delivery command to the identified delivery means.

  In addition to the features of the invention described in claim 15, the invention described in claim 16 includes the delivery request reception time, location information included in the delivery request, storage means specified as the delivery source, and the specified delivery destination. , The specified delivery means, the delivery status, the departure time of the delivery source, the estimated arrival time at the delivery destination, the presence / absence of treatment agreement, the presence / absence of insurance coverage, and at least one of the delivery via the communication network It further has a process notification means for transmitting to the member who issued the request or a predetermined related party of the member.

  In addition to the features of the invention described in any one of claims 1 to 16, the invention described in claim 17 confirms the intention to join through the communication network, and transmits member information including at least a member name to the communication. It further has an admission receiving means that is made to function by a computer, which is obtained through a network, inputs a predetermined questionnaire response through the communication network, and provides feedback based on the questionnaire response result through the communication network. And

  According to an eighteenth aspect of the present invention, in addition to the features of the invention according to any one of the first to seventeenth aspects, the delivery request receiving means includes a dedicated connection section with a communication network for the delivery request. And determining that the delivery request has been transmitted by receiving data.

  According to a nineteenth aspect of the present invention, in addition to the features of the invention according to any one of the first to seventeenth aspects, the delivery request receiving means has a connection part with the communication network, It is determined that the delivery request has been transmitted by detecting predetermined data characterizing the delivery request from the received data.

  The invention according to claim 20 is characterized in that, in addition to the features of the invention according to any one of claims 1 to 19, the therapeutic self-cells are cerebral infarction, cerebral hemorrhage, spinal cord injury, myocardial infarction, subarachnoid. Including stroke including bleeding, central and peripheral demyelinating diseases, central and peripheral degenerative diseases, brain tumors, higher dysfunctions including dementia, mental illness, epilepsy, head trauma and brain contusion and spinal cord injury It is used for the treatment of at least one of traumatic nervous system disease, inflammatory disease, and brain cell damaging infectious disease including Jacob disease.

  According to a twenty-first aspect of the present invention, in addition to the features of the invention according to any one of the first to twentieth aspects, the therapeutic self-cells are mesenchyme collected in an undifferentiated state from a member's body. It is a stem cell.

  According to a twenty-second aspect of the present invention, in addition to the features of the invention according to any one of the first to twentieth aspects, the therapeutic self-cells are mesenchyme collected in an undifferentiated state from a member's body. It is characterized by adding genetic manipulation to a stem cell.

  In addition to the features of the invention described in any one of claims 1 to 20, the invention described in claim 23 is characterized in that the therapeutic self-cells are mesenchyme collected in an undifferentiated state from a member's body. It is characterized by inducing differentiation of a stem cell.

  The invention described in claim 24 is a computer that requests appropriation for expenses from the therapeutic self-cell delivery support system according to any one of claims 1 to 23 and the collected money collected from the member. A cost appropriation requesting unit that is made to function by the said cost appropriation requesting unit, and the cost appropriation requesting unit periodically requests the appropriation to the maintenance and management costs that occur regularly, and occurs in accordance with the delivery request. Requesting the appropriation for temporary expenses such as delivery in response to the delivery request.

  According to a twenty-fifth aspect of the invention, in addition to the features of the invention of the twenty-fourth aspect, the cost appropriation requesting means responds to the request for delivery from the collection fee for the treatment cost related to the delivery request. Is required.

  According to a twenty-sixth aspect of the invention, in addition to the features of the twenty-fourth aspect of the invention, the cost appropriation requesting means applies the appropriation from the collected fee to the treatment cost related to the delivery request. It is characterized in that it is requested in response to the delivery request as an expenditure of insurance money from an insurance with at least a part of the insurance premium.

  In addition to the features of the invention described in claim 26, the invention described in claim 27, when the cost appropriation requesting unit requests the payment of insurance money to be applied to the treatment cost accompanying the delivery request, Based on the insurance contract and the reason for the delivery request, it is confirmed in advance whether the insurance contract is liable or irresponsible. It is characterized by notifying a person.

  In addition to the features of the invention described in claim 26 or 27, the invention described in claim 28 confirms the intention to join the insurance through the communication network, and also includes predetermined information necessary for insurance purchase. It further has insurance subscription acceptance means that is made to function by a computer and obtains at least a part of the information through the communication network.

  In addition to the features of the invention described in any one of claims 26 to 28, the invention described in claim 29 includes a collection fee including an insurance fee for each of when the insurance is enrolled and when not enrolled, It further comprises insurance design providing means for transmitting a typical design including the cost when making the delivery request and the insurance money through the communication network.

  The invention according to claim 30 is used for treatment for in vivo damage site regeneration treatment by in vivo administration to the member himself / herself collected from the member's body and grown to at least the amount necessary for treatment after the collection. Storing the autologous cells in the storage means separately for each member, ID information uniquely corresponding to the member in which the therapeutic self cells are stored in the storage means, and at least the member name including the member name Member information storage step implemented by a computer for storing member information in association with each other, ID information of a member who needs delivery to the delivery destination of the therapeutic self-cell for treatment, and position information of the member A delivery request received by a computer, received by a communication network, and received by the delivery request. A member information retrieval step implemented by a computer for retrieving member information of the member from the member information stored in the member information storage step based on the ID information included in the received delivery request; and the storage And a delivery request output step for outputting the member information retrieved in the member information retrieval step and the location information of the member for outputting information related to the means.

  According to a thirty-first aspect of the present invention, there is provided a computer for requesting appropriation for expenses from each step included in the therapeutic self-cell delivery support method according to the thirty-third aspect and a collected fee collected from the member. A cost appropriation request step that is performed, and the cost appropriation request step periodically requests appropriation for maintenance costs that occur regularly, and is accompanied by the delivery request. A request for appropriation for temporary expenses such as delivery is made in response to the delivery request.

  According to a thirty-second aspect of the present invention, in addition to the features of the thirty-first aspect, the cost appropriation request step includes an appropriation from a collection fee for a treatment cost related to the delivery request. It is characterized by requesting accordingly.

  According to a thirty-third aspect of the present invention, in addition to the features of the thirty-second aspect of the present invention, the cost appropriation request step includes an appropriation from a collection fee for a treatment cost related to the delivery request. It is characterized in that it is requested in accordance with the delivery request as an expenditure of insurance money from an insurance with at least a part of the insurance premium.

  The invention as set forth in claim 34 is used for treatment for in vivo damage site regeneration treatment by in vivo administration to a member who has been collected from the member's body and grown to at least the amount necessary for treatment after the collection. Storage means for storing autologous cells separately for each member, member information of the member including ID information uniquely corresponding to the member storing the therapeutic self-cells in the storage means, and at least a member name Member information storage means that is made to function by a computer and stores ID information of a member that requires delivery of the therapeutic self-cells to a delivery destination for treatment and a position of the member A delivery request receiving means operable by a computer for receiving a delivery request including location specifying information of the computer via a communication network; and Information related to the storage means, and a member information search means that is made to function by a computer for searching the member information of the member from the member information storage means based on the ID information contained in the delivery request received And a delivery request output means for outputting the member information searched by the member information search means and the position specifying information of the member.

  In addition to the feature of the invention described in claim 34, the invention described in claim 35 further includes position specifying means for obtaining the position information based on the position specifying information.

  According to a thirty-sixth aspect of the present invention, in addition to the features of the thirty-fifth aspect, the storage means and the delivery request output means exist in a plurality of geographically different positions, and are specified by the position specifying means. Based on the location information of the member, an appropriate delivery destination to which the member should receive treatment is specified from among locations including a plurality of treatment facilities registered in advance, and the appropriate storage means among the plurality of storage means As a delivery source, a delivery source identification means that is caused to function by a computer, member information that includes at least a member name retrieved by the member information retrieval means, and delivery destination information relating to the identified delivery destination A delivery request transfer means that is made to function by a computer and that is sent to a delivery request output means associated with a delivery means storage means specified by the origin specifying means. , Further comprising a, and the delivery request output means, transmitted by the delivery request transfer means, and outputs the member information and the shipping information, and wherein the.

  According to a thirty-seventh aspect of the present invention, in addition to the features of the thirty-sixth aspect, the storage means specified by the delivery source specifying means as the delivery source has the shortest delivery time to the specified delivery destination. It is a storage means in a geographical position.

  In addition to the features of the invention described in any one of claims 34 to 37, the invention described in claim 38 records the ID information of the member and transmits the ID information via the communication network. It further comprises ID information storage means for transmitting to the delivery request receiving means.

  According to a thirty-ninth aspect of the present invention, in addition to the feature of the thirty-eighth aspect, the ID information storage means is an external memory element storing the ID information.

  In addition to the feature of the invention of claim 39, the invention according to claim 40 is characterized in that the external memory device transmits the ID information of a member when the ID information storage means is connected to a computer terminal. A program for transmitting to the delivery request receiving means via the network is further stored.

  In addition to the feature of the invention described in claim 39, the invention described in claim 41 is characterized in that the external memory element determines the position of the computer terminal when the ID information storage means is connected to the computer terminal. A program for transmitting location specifying information for specifying the location to the delivery request receiving means via the communication network is further stored.

  In addition to the features of the invention according to any one of claims 39 to 42, the position information transmission program may be provided to the operator of the computer terminal on which the operation is performed. An input is prompted, and the input information is transmitted to the delivery request receiving means as position specifying information.

  The invention according to claim 43 is characterized in that, in addition to the features of the invention according to any one of claims 39 to 42, the external memory element is in the form of a USB key.

  The invention according to claim 44 is used for therapeutic treatment for in vivo damage site regeneration treatment by in vivo administration to a member who has been collected from the member's body and grown to at least the amount necessary for treatment after the collection. Storage means for distinguishing and storing autologous cells for each member, ID information uniquely corresponding to the member storing the therapeutic self-cells in the storage means, and member information of the member including at least a member name Member information storage means that is made to function by a computer and that stores position identification information for specifying the position of the member via a communication network at all times. And facility location storage means for storing the facility and facility location information in association with each other, and location information specified from the received location specification information And location information stored in the location storage means to confirm the presence / absence of a facility corresponding to the location information of the member, and a facility corresponding to the location information of the member by the location comparison means If it is determined, the distribution request transmission means for issuing a distribution request including the ID information and position information of the member, and the ID information issued by the distribution request transmission are acquired, and based on the ID information, the member Member information retrieval means for retrieving the member information from the information storage means, functioning by a computer, member information retrieved by the member information retrieval means for outputting information in association with the storage means, and Delivery request output means for outputting the location information of the member.

  According to a 45th aspect of the present invention, in addition to the feature of the invention according to the 44th aspect, the delivery request sending means confirms whether or not to issue a delivery request to the member before issuing the delivery request. It is characterized by performing.

  According to a 46th aspect of the present invention, in addition to the feature of the invention according to the 45th aspect, the delivery request sending means includes at least one of a facility professional index and a time before issuing a delivery request. It is characterized by determining whether or not to issue the delivery request based on the next index.

  According to the present invention, therapeutic self-cells collected from a member are stored in a storage means, a self-cell delivery request including ID information and location information is received from the member, and member information is searched based on the ID information. In order to output member information and location information for delivering self-cells from the storage facility of the delivery source to the delivery destination facility, the stored self that exhibits a therapeutic effect by rapid in-vivo administration for urgent disorders The effect that regenerative medicine using cells can be effectively supported is obtained. According to the present invention, according to the present invention, there are a plurality of storage means at geographically different locations, and the storage means are selected in a distributed manner in order to select the storage means with the shortest delivery time based on the member location information included in the delivery request. The effect is that the self-cells can be delivered in the shortest delivery time from the nearest storage means. In addition, according to the present invention, it is possible to issue a delivery request automatically by an ID information storage means that transmits ID information manually or automatically, by a simple operation, or by monitoring physical condition data. Even in an emergency situation or when the level of consciousness or motor / sensory ability declines, the delivery request can be reliably issued. In addition, according to the present invention, when an abnormality is detected in the physical condition data, the fact is once output, and then the ID information is transmitted on the condition that the confirmation input is not made within a predetermined time. Therefore, it is possible to automatically issue a delivery request while preventing malfunctions in preparation for a case where the patient's consciousness is reduced. In addition, according to the present invention, since the position of the member can be automatically obtained using GPS or the like and transmitted in the delivery request, the accurate position of the member can be known, and the delivery source and The effect that the delivery destination can be specified reliably is obtained. In addition, according to the present invention, in order to store physical feature data for identification of a member and provide it to a delivery source as member information, even if the member is unconscious, a third party The effect is that it can be reliably identified that the member is the member. In addition, according to the present invention, since the prior agreement of the member can be obtained, even if the member is not conscious in an emergency, it is possible to start treatment without having to obtain permission to treat again. can get. In addition, according to the present invention, a delivery time from a delivery source to a delivery destination in order to identify an appropriate delivery means from a plurality of delivery means existing at different geographical locations and send a delivery command to the delivery means. It is possible to obtain an effect that the delivery can be started by selecting the delivery means with the shortest. In addition, according to the present invention, the receiving time of the delivery request, the location information included in the delivery request, the storage means specified as the delivery source, the specified delivery destination, the specified delivery means, the delivery status, the delivery source, Since the departure time, estimated arrival time at the delivery destination, treatment agreement, insurance coverage, etc. are transmitted via the communication network, members or members of the members must check the progress of the delivery process in real time. The effect of being able to be obtained. In addition, according to the present invention, in order to confirm enrollment intention, obtain member information, input a questionnaire, and perform questionnaire feedback through a communication network, a series of membership, membership registration, survey upon enrollment, and advice based on the survey It is possible to obtain the effect that the procedure can be performed through the Internet. In addition, according to the present invention, since it has a dedicated connection part with the communication network for the delivery request, it is judged that the delivery request has been transmitted by receiving the data, and the system is surely activated. The effect of being able to be obtained. In addition, according to the present invention, a connection unit with a communication network is provided, and it is determined that the delivery request has been transmitted by detecting predetermined data that characterizes the delivery request from the received data. The effect that the system can be started is obtained. In addition, according to the present invention, therapeutic autologous cells delivered in a short time allow myocardial infarction, stroke including subarachnoid hemorrhage, central and peripheral demyelinating diseases, central and peripheral degenerative diseases, Brain tumors, higher dysfunctions including dementia, mental illness, epilepsy, traumatic nervous system diseases including head injury, brain contusion and spinal cord injury, inflammatory diseases, and brain cell damaging infectious diseases including Jacob disease The effect that it can be treated is obtained. In addition, according to the present invention, therapeutic autologous cells are obtained by genetic manipulation of mesenchymal stem cells collected from a member's body in an undifferentiated state, or collected from a member's body in an undifferentiated state. By making the mesenchymal stem cells differentiated, a wide range of regenerative medicine can be obtained.

  According to the present invention, according to the present invention, it is required to regularly apply to the maintenance and management costs that occur regularly from the collected money from the member, and to apply to temporary expenses such as delivery that accompanies the delivery request. Therefore, it is possible to appropriately allocate the regular expenditure and the contingent expenditure from the collected money, and it is possible to operate the system having financial support. In addition, according to the present invention, since the appropriation from the collection fee for the treatment cost related to the delivery request is requested according to the delivery request, not only the operation of the system but also the cost required for the treatment is collectively collected from the collection fee. The effect that it can be applied is obtained. According to the present invention, according to the delivery request, the appropriation from the collection fee to the treatment cost related to the delivery request is requested as a payment of the insurance money from the insurance having at least a part of the collection fee as the insurance premium. Therefore, it is possible to clearly show how much the contingent expenses for treatment are compensated for by mutual contribution in advance as the relationship between the insurance premiums received and the insurance premiums paid. In addition, according to the present invention, an opportunity to prepare expenses to check whether the insurance contract is liable or irresponsible in advance, and to notify that it is irresponsible through the communication network if irresponsible Can be provided at an early stage. In addition, according to the present invention, since the intention to join the insurance is confirmed and the subscriber information is acquired through the communication network, a series of procedures for joining the insurance can be performed through the Internet or the like. . According to the present invention, according to the present invention, a typical design including a collection including insurance premiums, a cost when a delivery request is made, and an insurance premium for each of the insurance participation and non-insurance is made through a communication network. Since it is transmitted, there is an effect that it is possible to give an opportunity to confirm the contents of the insurance and to impress the advantage of the insurance when a delivery request is made.

  In addition, according to the present invention, a communication request includes a delivery request including ID information of a member who needs delivery to a delivery destination of therapeutic self-cells for treatment and location specifying information for specifying the location of the member. Effectively supports regenerative medicine using self-cells by delivering therapeutic self-cells to the member without directly transmitting the member's location information. The effect that it can be obtained. In addition, according to the present invention, by obtaining the position information based on the position specifying information, there is an effect that the position information of the member can be specified reliably. According to another aspect of the present invention, the member ID information is stored in an external memory element such as a USB key, and preferably further when the member ID information is transmitted to the computer terminal via a communication network. Or a device for transmitting position specifying information of a connected computer terminal via a communication network is stored in the external memory element so that a member can easily carry a member and the position of the member. The effect that it can be made to function in order to specify is acquired. In addition, according to the present invention, the external memory element is in the form of a USB key, so that a USB key having a wide range of versatility and excellent portability can be specified to identify a member and the position of the member. The effect that it can be made to function is acquired.

  In addition, according to the present invention, it is possible to autonomously determine whether or not delivery of therapeutic self-cells to a member is necessary by constantly monitoring member position information. In addition, according to the present invention, in addition to the constantly monitored position, whether or not there is a delivery request based on secondary indicators such as confirmation of delivery request to members and location information of facilities, time, etc. By determining, it is possible to improve the accuracy of determining whether there is a delivery request.

(Mechanism of treatment with therapeutic autologous cells to which the present invention can be applied)
The therapeutic self-cell delivery support system according to the present invention supports regenerative medical treatment that does not require surgical operation using therapeutic self-cells. The therapeutic autologous cells are those obtained by proliferating autologous cells collected in an undifferentiated state from the member's body to an amount necessary for treatment. The mechanism of treatment with therapeutic autologous cells is as follows.

  There are hematopoietic stem cells and “mesenchymal stem cells (MSCs)” as stem cells in the bone marrow. The term “stem cell” as used herein refers to an undifferentiated cell that has both the ability to self-proliferate and the ability to differentiate into a cell having a specific function in the process of physiological growth and differentiation of cells constituting a living body. That is. Hematopoietic stem cells are stem cells that differentiate into red blood cells, white blood cells, or platelets. When mesenchymal stem cells differentiate into nerves via neural stem cells, differentiate directly into nerves without going through neural stem cells, differentiate into neurons via stromal cells (however, they are inefficient) It is known that when it differentiates into the vascular system, it may differentiate into bone, cartilage, fat or muscle. Although the present invention mainly uses mesenchymal stem cells, it should be noted that hematopoietic stem cells and other stem cells in the body may be used. Mesenchymal stem cells are obtained by isolation from bone marrow cells collected from bone marrow. Bone marrow cells from which mesenchymal stem cells have not been isolated can be used for treatment in the same manner as mesenchymal stem cells, although their effectiveness is slightly inferior. Further, cells obtained by genetic manipulation of mesenchymal stem cells or cells in which specific factors are allowed to act can also be used for treatment. Furthermore, cells that have been induced to differentiate from mesenchymal stem cells, specifically neural stem cells, nervous system cells, erythrocytes, leukocytes, platelets, myocardium, progenitor cells thereof, etc. are considered to be usable for treatment. Yes.

  A single bone marrow cell is collected after subjecting the subject to local anesthesia, and the appropriate amount is about several ml. The test subject is a user of the therapeutic self-cell delivery support system 100, and is registered as a member through a predetermined procedure in order to ensure management. Mesenchymal stem cells used for treatment are limited to those collected from or derived from the member's body unless a special operation such as immunosuppression is performed to prevent rejection due to an immune response. . Since the collected mesenchymal stem cells can be proliferated and cultured, they can be proliferated in advance to an amount necessary for treatment using the mesenchymal stem cells. Proliferated mesenchymal stem cells can be stored for a long time by a predetermined method such as freezing, and can be quickly returned to an active state and used for treatment of its members when necessary. it can.

  Here, the observation that mesenchymal stem cells can be used to perform regenerative treatment having the following extremely large features has been obtained. In other words, regenerative treatment using mesenchymal stem cells has been used to administer mesenchymal autologous cells by intravenous injection (intravenous injection) to the nervous system, which was impossible in the past. Administration), the damaged site can be regenerated and the disorder can be cured. In particular, it has been confirmed that it is effective against damage to the nervous system due to cerebral infarction, cerebral hemorrhage, spinal cord injury, and the like, and particularly cerebral infarction has been strictly verified. In addition, myocardial infarction, stroke including subarachnoid hemorrhage, central and peripheral demyelinating diseases, central and peripheral degenerative diseases, brain tumors, higher dysfunction including dementia, mental illness, epilepsy, head This treatment is also effective for traumatic nervous system diseases including trauma, brain contusion and spinal cord injury, inflammatory diseases, and brain cell damaging infectious diseases including Jacob disease. Such treatment can be performed at a prescribed treatment facility or even in the field. Considering that it is possible to cure a disorder that could not be treated in the past and that it is possible by simple treatment such as intravenous administration, this is an epoch-making treatment. I understand. Moreover, since damage to the nervous system causes a serious disability to the patient, the benefit that the patient can obtain from the healing of the disability is extremely great, and thus has great social significance. The medical mechanism of this regenerative treatment is that the mesenchymal stem cells migrate to the affected area (injured part of the living body) and settle there, and differentiate into appropriate cells to restore the function of the affected area. Is believed to be due to For this reason, it is thought that an effect is acquired for all kinds of diseases and accidents involving nervous system damage. Administration of mesenchymal stem cells into the body is basically performed once in a vein, but may be performed in multiple times. Further, instead of intravenous administration, local administration or other administration methods (intraarterial administration, intrathecal fluid administration, intraventricular administration) may be used.

(Therapeutic effect of cerebral infarction by administration of mesenchymal stem cells)
The extent to which damaged tissues can be recovered by regenerative medicine using mesenchymal stem cells will be described with reference to the results of experiments using rats. FIG. 16 is an MRI image showing, as an image, the result of intravenous administration of mesenchymal stem cells (1 × 10 ⁶ cells) to severe cerebral infarction (rat middle cerebral artery permanent occlusion model). In the figure, the results are shown separately for each elapsed time from the occurrence of the disorder to the administration of the mesenchymal stem cells. From the top, there are images of no treatment, treatment after 3 hours, treatment after 6 hours, treatment after 12 hours, treatment after 24 hours, and treatment after 72 hours. Each is based on MRI examination (T2WI) one week after the occurrence of cerebral infarction. In the image, the cerebral infarction is depicted in white. The cerebral infarction clearly recognized in the non-treated group (the uppermost stage) is only slightly observed in the group in which mesenchymal stem cells were intravenously administered 3 hours after the cerebral infarction. This therapeutic effect is more prominent as the treatment (transplantation) is faster, but it should be noted that a certain degree of therapeutic effect can be seen even when treatment is performed at least 24 hours after cerebral infarction. The therapeutic effect is considered as a synergistic effect of neuroprotective effect and nerve regeneration effect. The early transplantation after cerebral infarction, the stronger the neuroprotective effect and anti-edema effect, and when treated relatively late, the neuroprotective effect is relatively weaker. Become stronger.

FIG. 17 is a graph quantitatively showing the result of intravenous administration of mesenchymal stem cells (1 × 10 ⁶ cells) to severe cerebral infarction (rat middle cerebral artery permanent occlusion model) as the volume of the cerebral infarction region. . In the figure, the results are shown separately for each elapsed time from the occurrence of the disorder to the administration of the mesenchymal stem cells. As can be seen from this graph, the lesion site that had reached about 500 mm ³ in the case of no treatment reached only 200 mm ³ in the case of treatment after 3 hours, and a remarkable effect was obtained. In the case of treatment by 12 hours later, the volume of the lesion site is clearly smaller than in the case of no treatment. It can also be seen that the earlier the treatment, the smaller the volume of the damaged site and the better the prognosis.

FIG. 18 is a graph showing the result of intravenous administration of mesenchymal stem cells (1 × 10 ⁶ cells) to severe cerebral infarction (rat middle cerebral artery permanent occlusion model) as a change in survival rate after the occurrence of injury. . In the figure, the results are shown separately for each elapsed time from the occurrence of the disorder to the administration of the mesenchymal stem cells. n is the number of samples. From this graph, it can be seen that treatment by intravenous administration of mesenchymal stem cells markedly improves the survival rate in severe cerebral infarction. 90% of the cerebral infarction model rats die in the case of no treatment, but all cases survive when mesenchymal stem cells are intravenously administered 3 hours after the occurrence of cerebral infarction. It is clearly shown that the earlier the treatment start time, the higher the survival rate. The survival rate after treatment is also an epoch-making value.

(Outline of treatment support by therapeutic autologous cells)
This regenerative treatment using mesenchymal stem cells is an extremely innovative treatment as described above, but has some limitations. One limitation is the use of stem cells (or derived from them) previously collected from the patient's own body. The most important limitation, however, is the need for prompt treatment within a predetermined time after the patient has failed. The later the start time of treatment from the occurrence of the disorder, the less effective treatment effect can be obtained. However, conversely, this also means that if a patient has a disorder and the time from treatment to treatment is short, a significant effect can be obtained. Therefore, in regenerative treatment using mesenchymal stem cells, mesenchymal stem cells collected from the patient's own body can be reliably delivered to the patient within a short time after the occurrence of the disorder, This is an extremely important point, and is a problem in implementing this regenerative treatment. Specifically, treatment (therapeutic time windows) is required within 6 hours and 72 hours at the latest from the occurrence of the disorder. In addition, when a disorder occurs, the patient's level of consciousness and motor / sensory ability may decrease. In order to cope with such a case reliably, it is necessary to be able to make a request for delivery of therapeutic autologous cells by a simple operation.

  As described above, the therapeutic autologous cells act like a kind of member-only medicine. However, specialized equipment is required to store therapeutic autologous cells. Therefore, in order to properly store the therapeutic self-cells of many members, it is preferable to provide storage facilities that are dedicated facilities for centralized management. When a member fails, it is necessary to prepare treatment autologous cells for the patient in a short time. Therefore, it is advantageous to install a plurality of such dedicated facilities at geographically different positions because it is possible to deliver the therapeutic autologous cells from any one of the closest locations. In addition, since the member needs treatment in an emergency when a disorder such as illness or accident occurs, a delivery request can be issued by conveying the member's information to the system with the simplest possible operation To do. A system that receives a delivery request from a member delivers a therapeutic self-cell from a storage facility that is an appropriate delivery source to a treatment facility that is an appropriate delivery destination to a delivery means that is an appropriate means of transportation. Issue a delivery order. The therapeutic self-cell delivery support system 100 according to an embodiment of the present invention performs an operation according to the above-described purpose.

  Here, the matter regarding the expense etc. regarding the self-cell delivery support system 100 for treatment is demonstrated. The operation of the therapeutic self-cell delivery support system 100 generates regular maintenance costs for storage of therapeutic self-cells and temporary expenses such as delivery for the delivery of therapeutic self-cells. Basically, you must pay for the membership. In order to cover these expenses, it is necessary to collect the collection fee from the member as a membership fee and to pay it appropriately. The membership fee is collected on a regular basis, such as every month or every six months, but it may be combined with a one-time payment fee such as an admission fee. By collecting a certain amount of admission fee, there is an advantage in that the funds on hand are abundant for the operating entity, and the periodic membership fee can be made relatively low for members. There are advantages. With regard to the expenditure related to a certain member, the expenditure may be made from the collected fee for each individual member, or may be made from the collected fee for the entire member. If you start to collect money from the entire member's collection, the collection has a stronger mutual meaning. Members also need to pay for treatment when receiving treatment with autologous cells for treatment. Therefore, in order to reduce the burden at the time of the treatment of the member, it is preferable to apply the treatment cost as a kind of temporary cost from the collected fee from the member. This treatment cost may be applied not only to the part related to regenerative medicine but also to the whole member treatment. Furthermore, a free combination of various related expenses including the self-payment of health insurance may be applied from the collected money. In addition, regarding the appropriation for treatment costs and related costs, a financial product such as an insurance with insurance premiums for at least a part of the collected fee from the member shall be established, and the insurance money for the insurance shall be applied to it. You can also. In this way, by setting insurance independently from the membership fee collection system, it is possible to determine how much the contingency costs for the necessary treatment will be compensated for by mutual contribution. In addition, the relationship between the received insurance premium and the premium paid can be clearly indicated to the applicant. Insurance premiums can also be collected through one-time payments, installment payments, or a combination thereof, as with membership fees. Regarding insurance, the therapeutic self-cell delivery support system 100 does not necessarily have to memorize even the detailed information of the paid premium, so the premium is properly paid and the insurance contract is not Only information on whether or not the information is valid can be managed.

  In addition, the temporary cost for delivery of therapeutic autologous cells may be considerably high depending on the type of delivery means 62 and the like. In addition, due to some reason, there may be a case where the payment of the membership fee of a member is delayed. Even when such financial support is scarce, it is desirable for a member to reliably deliver therapeutic self-cells to the member who issued the delivery request. However, in any case, if the delivery of therapeutic self-cells is performed, the financial soundness of the operating entity of the therapeutic self-cell delivery support system 100 is impaired, and the normal operation thereof is hindered. There is also a fear that this may lead to a disadvantage of the member. In order to prevent this, it is conceivable that a part of the collected membership fee is accumulated as a prepaid pool money, and in particular when a temporary expense such as delivery occurs, the shortage of the membership fee is paid from here. The prepayment pool money may be a member individual unit, a member as a whole, or a combination of them as appropriate. In this way, it is possible to achieve both the financial soundness of the operating subject of the therapeutic self-cell delivery support system 100 and the certainty of treatment for members.

(Embodiment)
A therapeutic self-cell delivery support system 100 according to an embodiment of the present invention will now be described with reference to the drawings. First, the configuration of the therapeutic self-cell delivery support system 100 will be described. FIG. 1 is a system configuration diagram showing the configuration of a therapeutic self-cell delivery support system 100. The therapeutic self-cell delivery support system 100 is largely composed of a delivery request unit 10, a delivery request processing unit 20, a storage facility 30, a communication network 40, and a member terminal 50. The therapeutic self-cell delivery support system 100 is connected to the delivery processing unit 60. It is preferable that the therapeutic self-cell delivery support system 100 is a membership organization. The therapeutic self-cell delivery support system 100 is an in vivo damaged site regeneration treatment that is collected in an undifferentiated state from a member's body, and is administered to the member who has been grown to at least the amount necessary for treatment after the collection. Is a system for issuing a command to the delivery processing unit 60 that stores the therapeutic autologous cells for the purpose and delivers it based on a delivery request issued by a member.

  The delivery request unit 10 includes an ID storage unit 11 and a location notification unit 12. The ID storage unit 11 stores ID information such as a member number uniquely corresponding to a member, and is a component for outputting it. The ID storage unit 11 typically includes a small semiconductor chip that stores information, and includes a communication unit that outputs the information. The ID storage means 11 preferably has a shape such as a card type suitable for a member to carry and carry. The ID storage unit 11 outputs ID information to the communication network 40 in response to a wireless signal for reading from outside. The ID information also represents a request for delivery of therapeutic self cells, and also serves to activate the therapeutic self cell delivery support system 100 for the member. The ID storage means 11 monitors member data such as heart rate, respiratory cycle, electrocardiogram pattern, voice, and body movement, and automatically detects ID information when an abnormality occurs in the data. It may be configured to output. In this way, even if the member loses consciousness, if there is an abnormality in the body, it is possible to reliably detect the member's abnormality and transmit the ID information. In this case, when the ID storage means 11 determines that an abnormality has occurred, the ID storage means 11 once outputs to the member that the abnormality has been detected. It is preferable to output the ID information on the condition that no confirmation input has been made. In this way, it is possible to prevent malfunction due to erroneous determination of the member's physical condition as abnormal.

  Alternatively, the ID information storage means 11 can be in the form of an external memory element that stores ID information such as a membership number. The external memory element can be in the form of a USB key, an SD card (registered trademark), a memory stick (registered trademark), or the like. In the case of an external memory device, an emergency display is attached to the outer surface, and when the person develops, the external memory device is attached and connected to a computer, and a procedure for receiving delivery of therapeutic autologous cells is performed. It is preferable to write a note. The ID information storage means 11 can be in the form of a memory element built in the mobile phone. Preferably, the external memory element further stores a program for transmitting member ID information to the delivery request receiving means via the communication network 40 when it is connected to the computer. If this program is automatically started, the member ID information can be automatically transmitted simply by connecting the external memory element to the computer.

  The position reporting means 12 is a component that outputs position information thereof. The location reporting means 12 typically has a GPS receiver function or a mobile phone company location information service reception function, thereby acquiring location information and outputting it to the communication network 40. . The location reporting means 12 preferably has a shape such as a portable device suitable for carrying by the member and carried around, thereby communicating the location information of the member carrying the location reporting means 12. It can be transmitted to the network 40. The location reporting means 12 can also transmit location information input by the member himself / herself by voice, button operation or the like to the communication network 40. The member's ID information and position information are basic information for the member to request the delivery of therapeutic self-cells, and will be referred to as a delivery request.

  The location reporting means 12 may be in the form of a mobile phone that has a GPS receiver or a location information service reception function of a mobile phone company and outputs location information acquired thereby. In this way, it is possible to prevent the member from forgetting to carry the location reporting means 12 by incorporating the location reporting means 12 into a mobile phone that is extremely popular and is likely to be carried when going out. .

  The member position information need not be direct position information such as represented by latitude and longitude, for example, and may be position specifying information that can indirectly specify position information. As the location specifying information, when the location reporting unit 12 communicates with the delivery request processing unit 20 through a computer terminal installed at a predetermined location, a terminal that specifies which computer terminal has communicated with the delivery request processing unit 20 Specific information can be used. In this case, although not shown, the delivery request processing unit 20 stores in advance the correspondence between the terminal identification information for identifying the computer terminal and the location where the computer terminal is installed, and based on the correspondence, Terminal specifying means for specifying the installation location of the terminal is provided. When the location reporting unit 12 is connected to a computer terminal, the location reporting unit 12 outputs terminal identification information for identifying the computer terminal. The location notification unit 12 is configured to receive location specification information for specifying the location of the computer terminal as the location of the member when the ID information storage unit is connected to the computer terminal via the communication network. It can be in the form of an external memory element that includes a program for transmitting to. In addition, the program included in the location reporting unit 12 displays a window that prompts the operator of the terminal to input a location when the terminal identification information is not stored in the computer terminal. It may be a program for transmitting to the delivery request receiving means as specific information. The external memory element can be in the form of a USB key, an SD card (registered trademark), a memory stick (registered trademark), or the like. In the case of an external memory device, an emergency display is attached to the outer surface, and when the person develops, the external memory device is attached and connected to a computer, and a procedure for receiving delivery of therapeutic autologous cells is performed. It is preferable to write a precautionary note, and it is more preferable that the configuration is integrated with the ID information storage unit 11.

  The delivery request processing unit 20 includes a delivery request receiving means 21, a member information search means 22, a member information storage means 23, an agreement confirmation means 24, a cost appropriation request means 25, a delivery source specifying means 26, a delivery request transfer means 27, a delivery command. It comprises means 28 and communication / control means 29. These forms do not need to have a separate physical configuration, but are configured such that a predetermined program is executed on a computer such as a server to cause the computer to function. The delivery request receiving unit 21 is a component that receives a delivery request via the communication network 40. The delivery request receiving means 21 can typically be in the form of a server such as a Web server connected to the communication network 40 and executing a communication application. The delivery request receiving means 21 can automatically transmit and receive a series of information to and from the delivery request unit 10 that issues a delivery request, and automatically information necessary for the subsequent stage based on the received delivery request. By transmitting this, it is possible to reliably start the delivery request processing unit 20. Alternatively, the delivery request receiving means 21 may input delivery request data obtained by interpreting the voice transmitted through the public telephone network.

  The member information search means 22 is a component that manages data of member information, and is typically in the form of a computer that performs database management. Member information includes ID information, password, name, gender, date of birth, address, telephone number, e-mail address, storage status of treatment self-cells (information on storage facility 30 stored, stored self-treatment Cell type, etc.), enrollment questionnaire results, insurance contract details, prior agreement, and information on members who can agree on treatment (in the absence of prior agreement). Can be securely registered. Furthermore, as member information, member identification information representing physical characteristics for identification such as a facial photograph image, a fingerprint pattern, a vein pattern, and an iris pattern can be used, and this information causes the member to become unconscious. However, it is possible for a third party to securely identify the member. Member information can also include medical information about the member, such as blood type, health checkup results, pre-existing diseases and their treatment status, common medications, drug allergies, etc. Information useful for emergency treatment can be transmitted to the site.

  The member information storage means 23 is a component that stores the member information. The member information storage means 23 is preferably in the form of a hard disk drive or the like in which data is stored, and stores various member information. The agreement confirmation means 24 is a component that obtains a prior agreement on treatment from a member through the network or obtains an agreement at the time of delivery when there is no prior agreement. The cost allocation request unit 25 is a component that manages money. The cost appropriation requesting means 25 monitors that the membership fee from the member (and the insurance fee if insurance is taken) is normally collected, and when the cost is incurred, the cost is calculated from the collected fee. Make a request to approve. The cost appropriation request means 25 is an additional component when the therapeutic self-cell delivery support system has a function as a financial system. The name is used for supporting financial systems.)

  The delivery source specifying means 26 specifies an appropriate delivery destination for the member to receive treatment from among locations including a plurality of pre-registered treatment facilities based on the position information of the member. This is a component that identifies an appropriate storage facility as a delivery source.

  The delivery request transfer unit 27 is a component that transmits a delivery request (member information and delivery destination information) to the transfer delivery request receiving unit 31 associated with the storage facility 30 specified by the delivery source specifying unit 26. Member information to be transmitted may include member identification information representing physical characteristics for identification. The delivery request may be transmitted through the communication network 40 or may be transmitted through another network. When only one storage facility 30 exists, the delivery source specifying unit 26 and the delivery request transfer unit 27 are not necessarily required. The delivery command means 28 is a component that transmits a delivery command for therapeutic self cells to the delivery command receiving means 61 in order to cause the delivery processing unit 60 to deliver the therapeutic self cells. If there are a plurality of delivery means 62, an appropriate one is selected based on the type and geographical position of the delivery means 62, and a delivery command is transmitted thereto. The communication / control unit 29 is a component that performs transmission / reception processing for the communication network of the delivery request processing unit 20 and related control, and transmits the progress of the delivery processing process to the member terminal 50 via the communication network 40. (Function as a process notifying means), and various information at the time of joining or the like is transmitted to and received from the member terminal 50. The member or the related person of the member can know the progress of the delivery process through the Internet or the like. The communication / control unit 29 is connected to each component included in the delivery request processing unit 20, receives the status thereof, and transmits the status via the communication network 40 as the status of the delivery request processing unit 20.

  The storage facility 30 includes a transfer delivery request receiving unit 31, a member identification information output unit 32, a delivery request output unit 33, and a storage unit 34. The storage facility 30 is a facility installed at one place or a plurality of geographically different places, and functions as a storage / delivery base for therapeutic autologous cells. The transfer delivery request receiving unit 31 is a component that receives the delivery request transmitted from the delivery request transfer unit 27 and is typically in the form of a network client such as a Web client. The member identification information output means 32 is a component that outputs member identification information that represents physical characteristics for identification from the delivery request transfer means 27, and thereby outputs it to the person in charge in the storage facility 30. Inform the physical characteristics for membership identification. The member identification information output means 32 is typically in the form of a display, a speaker or the like. The delivery request output means 33 is a component that outputs the received delivery request, and thereby, information on the member who requests delivery of the treatment self-cells to the person in charge in the storage facility 30 and the delivery destination. Is output. The delivery request output means 33 is typically in the form of a display, a speaker, etc., and it is preferable that additional information such as a map can also be output. The storage means 34 is a component that stores therapeutic autologous cells. The storage means 34 is typically stored frozen by storing the member's treatment autologous cells in a predetermined container and holding at a low temperature (for example, minus 196 ° C., which is the boiling point of liquid nitrogen at normal pressure). It has the structure for doing. Member autologous cells for treatment are stored in a strictly distinct manner by labeling each member. Moreover, even if it is the self-cell for a treatment of the same member, several types of self-cell for a treatment can be distinguished and stored.

  The communication network 40 is a component composed of a network organization that mediates information transmission, and is typically in the form of an information communication network such as the Internet or a leased line network. When information is transmitted by voice, it may be a public telephone network.

  The member terminal 50 is a component that is connected to the communication network 40 and inputs / outputs and operates information. Typically, the member terminal 50 is a personal computer equipped with a Web browser, a mobile phone, a PDA or the like. . A member who wants to join, a member, or a member concerned (such as a member's family) exchanges information related to the member through the member terminal 50.

  The delivery processing unit 60 connected to the therapeutic self-cell delivery support system 100 includes delivery command receiving means 61 and delivery means 62. The delivery command receiving unit 61 is a component that receives and outputs a delivery command from the delivery command unit 28, and is typically in the form of a network client such as a Web client. The delivery command unit 28 and the delivery command receiving unit 61 may be connected via the communication network 40. The delivery means 62 is a transportation means for delivering the therapeutic self-cells stored in the storage facility 30 to a delivery destination such as a hospital, and is typically an automobile, a motorcycle, a helicopter, or the like. The person in charge who sees the delivery command output from the delivery command means 28 delivers the therapeutic self-cells from the storage facility 30 to the delivery destination using the delivery means 62.

  Next, with reference to the drawings, a configuration of a therapeutic autologous cell delivery support system 101 according to another embodiment of the present invention will be described. The therapeutic self-cell delivery support system 101 automatically determines that the member has entered a facility such as a hospital by constantly monitoring the position information of the member with respect to the therapeutic self-cell delivery support system 100. The point that can be different. FIG. 19 is a system configuration diagram showing the configuration of the therapeutic self-cell delivery support system 101. The therapeutic self-cell delivery support system 101 includes the same components as the therapeutic self-cell delivery support system 100, and further includes a constant position notification means 71, a constant position reception means 72, a position comparison means 73, and a facility position memory. Means 74 and delivery request confirmation means 75 are included. Components having the same reference numerals as those of the therapeutic self-cell delivery support system 100 have the same configurations and functions.

  The always-on position notification means 71 is a component that always outputs its position information. The location reporting unit 12 is used to include location information when a member issues a delivery request, whereas the regular location reporting unit 71 actively reports the regular location of the member. The difference is that the position of the member is monitored. The always-on location reporting means 71 typically has a GPS receiver function, a mobile phone company location information service, an ad hoc network locator, and other receiving functions, thereby acquiring location information and communicating it. Always output to the network 40. The always-on location reporting means 71 preferably has a shape such as a portable device suitable for a member to carry and carry, so that the location information of the member carrying the always-on location reporting means 71 is obtained. Alternatively, the position specifying information can be constantly transmitted to the communication network 40. The constant position reporting means 71 may be the same one as the position reporting means 12 so that the operation is always performed. In this case, the always-on position notification means 71 can include the position notification means 12 structurally and functionally.

  The constant position receiving means 72 is connected to the constant position notification means 71 via the communication network 40. The constant position receiving means 72 receives the member position information or position specifying information from the constant position notification means 71 and transmits it to the position comparison means 73.

  The position comparison means 73 compares the position information of the member transmitted from the constant position reception means 72 with the position information of a facility such as a hospital stored in the facility position storage means 74, and the position information is stored for the member. It is a component that determines whether or not it is in the facility. The position comparison means 73 searches for a facility located within a predetermined distance from the position information using the transmitted position information as a search key. The facility where the location information stored in the facility location storage means 74 is searched and the location information is stored by the facility location storage means 74 is a treatment facility for a disease that can be treated with therapeutic self-cells. Such treatment facilities include emergency hospitals, general hospitals, brain surgery hospitals, etc., depending on the type of illness. If the position information of the member matches the position information of the facility, the position comparison unit 73 determines that the member has entered the facility, and notifies the delivery request confirmation unit 75 to that effect. The position comparison means 73 can make an additional determination based on a secondary index other than the position, and can enhance the determination system. For example, the facility location storage means 74 can also store a specialty index corresponding to the specialty for each hospital, and the location comparison means 73 determines whether or not delivery is necessary based on the comparison of location information. A highly accurate determination can be made. For emergency hospitals specializing in cerebral infarction treatment, use the highest level of professional index, and for emergency hospitals, the next higher level of professional index. This can be used in the determination, for example, by increasing the probability of determining. The position comparison unit 73 can also use the time as a determination index. For example, in the case of midnight or early morning, it is unlikely to go to the hospital at such a time during normal times, so the probability of determining that delivery is necessary can be increased.

  The delivery request confirmation means 75 confirms whether or not to issue a delivery request for the member determined to have entered the facility by the position comparison means 73 and, after confirmation, issues a delivery request from the ID information and position information of the member. It is generated and transmitted to the delivery request processing unit 20, and a delivery request for therapeutic autologous cells is issued. The delivery request confirmation as to whether or not to issue a shipping request can be performed by various methods. For example, the delivery request confirmation means 75 automatically sends a telephone call or e-mail to the member himself / herself and confirms the presence / absence of a delivery request based on the response, or sends a call or e-mail to the person in charge at the facility. The delivery request confirmation means 75 outputs the member location information to the operator on the operating subject side and accepts the input of the delivery request determined by the operator, thereby confirming the delivery request. Can be confirmed. For confirmation to the member himself / herself, a dedicated delivery request confirmation receiving means for receiving the delivery request confirmation from the delivery request confirmation means 75 and outputting it to the member in close proximity to the location notification means 71 and confirming the delivery request there is provided. It can also be done by sending. When it is confirmed that the delivery request has been issued, the delivery request confirmation unit 75 transmits the delivery request to the delivery request processing unit 20. The delivery request can also include information on the facility determined to have entered the member, and transmit information on the facility that is the delivery destination so that the delivery means 62 can smoothly deliver the therapeutic self-cells. You can also.

  An operation for storage of therapeutic self cells, which is a preparation stage of the operation of the therapeutic self cell delivery support systems 100 and 101, will be described with reference to an operation flowchart. FIG. 20 is an operation flow diagram showing the operation of the therapeutic self-cell delivery support systems 100 and 101 until the storage of the therapeutic self-cells into the storage facility 30. In FIG. 20, the block in the upper dotted line represents the flow relating to the specimen (self cell), the block in the middle dotted line represents the flow relating to the member information storage means 23 for storing member information, and the block in the lower dotted line Represents a flow relating to an IC tag. The IC tag is affixed to a sample container and stores information such as a sample number for identifying the sample. Information is written and read out in a contactless manner. In FIG. 20, the block in the left dotted line represents the flow part in the hospital / research facility, the block in the central dotted line represents the flow part in the transfer means, and the block in the right dotted line represents the storage facility 30. Represents the part of the flow.

First, a member who wants to collect autologous cells collects specimens (autologous cells) in a hospital / research facility (step S51). A sample is collected from the bone marrow in a necessary amount, for example, about 5 ml. The collected specimen is examined biochemically to determine whether it is suitable as a therapeutic autologous cell (step S53). The biochemical information of the examined specimen is stored in the member information storage unit 23 in association with the member ID information (step S55). A sample number for identifying the sample is input to the IC tag attached to the sample container (step S57). This sample number is stored in the member information storage means 23 in association with the member ID information. If the hospital / research facility is located at a location different from the storage facility 30, after reading the sample number from the IC tag to identify the sample (step S59), the sample is insured by transport means such as an automobile. 30 (step S61). The transferred specimen is received by the storage facility 30 (step S63). At the time of acceptance, the specimen number is read from the IC tag and collated (step S65). The biochemical specimen information stored in the member information storage means 23 is output (step S67) and used for subsequent specimen processing. At the time of sample reception, reception information such as reception date, reception amount, and cell type is input to and stored in the member information storage unit 23 (step S69). Next, stem cells are separated from the specimen, and cells are prepared (step S71). Next, the specimen is cell-cultured and grown to at least the amount necessary for treatment (step S73). The required amount is typically about 10 ⁸ . The cultured autologous cells are examined to determine whether they are suitable for treatment (step S75). The test result of the culture result is input to and stored in the member information storage unit 23 (step S77). The autologous cells that have been cultured and determined to be suitable for treatment in the examination are stored in the storage means together with the container for storing them as therapeutic autologous cells and stored frozen (step S79). The storage means is a refrigeration facility whose temperature is controlled to a predetermined low temperature. Storage information such as storage start date, storage deadline, storage amount, and cell type is input to the member information storage means 23 and stored (step S81). In this state, the therapeutic autologous cells can be stored for a long time.

  When the delivery request issued from the member is received in the storage facility 30 (step S83), the specimen number is read from the IC tag to identify the therapeutic self-cell (step S85), and the corresponding therapeutic self-cell is stored in the storage means. And are shipped to the delivery destination (step S87). Thawing from the frozen state may be performed before shipment, or may be performed after arrival at the delivery destination. Preferably, it should be put in a dedicated portable thawing device immediately after delivery and during delivery. It is desirable to perform thawing while performing temperature control. If it does in this way, it can be made the state which can use the preserve | saved therapeutic self-cell in the shortest time. The delivery information such as the delivery date is input to and stored in the member information storage means 23 (step S89).

  The operation of the therapeutic self-cell delivery support system 100 (hereinafter abbreviated as “the present system 100”) will be described with reference to an operation flowchart. 2 to 5 are operation flowcharts showing typical operations of the system 100. 6 to 15 are image diagrams of main screens. First, the process from the reception of a member's membership to the flow of processing in a steady state will be described. The admission is typically received on the screen of the member terminal 50 via the communication network 40 which is the Internet.

  First, the communication / control unit 29 provides a Web site for joining the service of the system 100 via the communication network 40 which is the Internet. When a prospective member accesses the system 100 through the website for membership registration from the membership terminal 50 via the communications network 40, the communication / control means 29 displays a screen for membership registration on the membership terminal. 50, and necessary member information data is acquired through the display (step S101). At the time of joining, the following processing is performed. First, the system 100 issues ID information that uniquely corresponds to a member, such as a member number, and allows the applicant to determine a password. Then, the user is prompted to input necessary items such as the member's name, gender, date of birth, address, telephone number, and email address. FIG. 6 is an image diagram of a member registration screen for this purpose. Next, the system 100 displays a screen for inputting the membership fee payment method (monthly payment, annual payment), the presence / absence and amount of the temporary payment at the time of membership, the bank name / account type / account number of the transfer account, etc. , Encourage applicants to input. FIG. 7 shows a membership fee collection method selection screen for this purpose. In addition, not only the input item of a transfer account but the input item about other payment means, such as a credit card, may be displayed. At the time of enrollment, an insurance enrollment screen for paying treatment expenses, temporary expenses such as delivery, etc. with insurance money is also displayed. That is, here, the intention to join the insurance is confirmed through the communication network 40, and at least a part of the predetermined information necessary for the insurance purchase is acquired through the communication network 40. FIG. 8 is an image diagram of an insurance subscription screen for this purpose. On the insurance subscription screen, multiple courses can be selected according to the coverage. For example, the insurance premium can be selected from a course of 50,000 yen, 30,000 yen, or 10,000 yen. It is also possible to enter payment methods (monthly payment, annual payment), whether or not there is a temporary payment at the time of subscription, and the amount, the bank name / account type / account number (or credit card number) of the transfer account. As for insurance courses, the maximum amount of insurance money is 500,000 yen for treatment costs, 300,000 yen for temporary expenses such as delivery, and 50,000 yen for insurance premiums. It is assumed that courses of Yen, 200,000, and 30,000 yen are provided, 100,000, 60,000, and 10,000 yen. For each course, in order to promote participation in insurance, insurance premiums, costs for delivery requests (costs for handling accidents and treatment costs), and insurance, when enrolled and not enrolled. It is preferable to display a typical design example of gold, and to impress the benefits of insurance coverage to promote insurance coverage. FIG. 14 is an image diagram of an insurance design example display screen (1) for this purpose, and FIG. 15 is an image diagram of an insurance design example display screen (2) for this purpose. The handling cost at the time of the accident here includes the delivery cost. The delivery cost is calculated by a predetermined calculation based on the address of the applicant, the location of the nearest storage facility 30, the type of the delivery means 62, and the like. It is preferable that it is obtained.

  At the time of enrollment, it is preferable to conduct a predetermined questionnaire that also serves as an inquiry. FIG. 11 is an image diagram of a questionnaire screen for this purpose. In the questionnaire, the risk factor for diseases / accidents that can be treated with autologous cells for treatment is an item. Items include, for example, occupation, wake-up time, bedtime, work time, work content, alcohol consumption, tobacco consumption, meal content, exercise time, stress level, history of stroke, history of stroke, family history of stroke, Age, sex, history of diabetes, presence or absence of hypertension, presence or absence of hyperlipidemia, tobacco use, alcohol use, pill use, obesity, etc. Each questionnaire item is given a predetermined risk contribution, and the risk of cerebral infarction can be calculated by calculation from the input result of the questionnaire and the risk contribution. Here, it is possible to change the insurance rate according to the questionnaire result (that is, the risk of cerebral infarction), but such differentiation is not necessary. Furthermore, by displaying the degree of risk and life advice according to the questionnaire result and performing simple counseling, the life attitude of the member can be corrected and the degree of risk can be reduced. Thus, it is preferable to perform feedback such as the risk of cerebral infarction and life advice. FIG. 12 is an image diagram of a life advice screen for this purpose. In the figure, the risk of cerebral infarction is evaluated as “B”. Furthermore, when the risk of cerebral infarction is high, it is also possible to display an examination guide such as a brain dock or an application screen. If the risk can be lowered by the effect of the life advice, the amount of money spent as temporary expenses such as delivery from the collected money is reduced, and the collected membership fee and insurance premium can be given a margin.

  Next, the agreement confirmation means 24 causes the member terminal 50 to display the explanation items about the treatment with the treatment self-cells, and obtains the agreement about the treatment as a part of the member information (step S103). The consensus here is informed consent, including the willingness to start treatment regardless of the member's condition when a disorder occurs (disease or accident). Here, it is very important to obtain an agreement by confirming the intention of treatment in advance, considering the possibility that the member may lose consciousness when a failure occurs. In addition, when displaying explanation items, a check column is provided for each explanation item, the input of important keywords in the explanation is requested, or the explanation items are reproduced by rearranging phrases. For example, it is preferable to encourage the understanding of the explanation of the person who joins. FIG. 9 is an image diagram of an explanatory matter confirmation screen for providing a check column. Here, when the agreement about the treatment intention is not obtained from the member, the agreement confirmation means 24 is information (name, address, telephone number (emergency contact) about the member concerned who can agree as a proxy approver for the treatment. (First), e-mail address, relationship, etc.) are urged from the member terminal 50 (step S105). The member's related person is a person who has a certain responsibility for the health of the member, such as a member's family, a company related person, or an attending physician. If it is not possible to confirm the intention of the member at the time of the failure, by confirming in advance that treatment may be started by an agreement (as a substitute for the principal) from these parties, You can contact the parties concerned to confirm the agreement. FIG. 10 is an image diagram of a prior agreement confirmation screen for confirming the presence / absence of prior agreement and inputting a proxy approver.

The member information acquired in the above step is stored in the member information storage unit 23 by the member information search unit 22 (step S107). The member who has joined collects the autologous cells for treatment at a predetermined facility such as a hospital, proliferates and cultures them to the amount necessary for treatment, and stores them in the storage means 34 (step S109). As a therapeutic autologous cell, a mesenchymal stem cell (MSC: mesenchymal stem cell) is collected from the bone marrow. That is, first, mesenchymal stem cells are separated from the collected bone marrow cells. The isolated mesenchymal stem cells are grown to an amount necessary for treatment, typically to an amount of about 1 × 10 ⁷ to 1 × 10 ⁸ cells. Proliferated mesenchymal stem cells are adjusted to be suspended in a solution of about several tens of cc. This is also a state where it can be administered as it is into the patient's body. Thereafter, the temperature is lowered to the target temperature by a program freezer and stored in a storage container filled with liquid nitrogen. In addition, genetic manipulation may be applied to mesenchymal stem cells, or specific factors may be allowed to work. In addition, cells induced to differentiate from mesenchymal stem cells, specifically, neural stem cells, nervous system cells, erythrocytes, leukocytes, platelets, myocardium, and progenitor cells thereof can be used as therapeutic autologous cells. In this case, basically, it is expected that induction into all cells will be possible in the future. Accordingly, the therapeutic self-cells may be of a plurality of types, and in this case, the storage means 34 distinguishes and stores the plurality of types. When the storage facility 30 and the storage means 34 are located at a plurality of geographically different locations, it is preferable that the storage means 34 is selected in consideration of a member's address and the like. The nearest storage means 34 may be the one having the shortest distance, or the one having the shortest delivery time in consideration of the transportation means and the traffic route, and having the shortest delivery time. May be. Of course, all or a plurality of storage facilities 30 may be used. In preparation for a business trip or the like, the storage facility 30 that has not been used before may be temporarily used. Further, when the residence is moved due to a member's transfer or moving, the therapeutic self-cells may be moved to the storage facility 30 close to the new residence. In such a movement, when the member accesses the system 100 through the Internet to change the registered address or the like, a candidate for a new storage facility 30 is displayed and selected, and it is confirmed that the member has been selected. It is preferable to perform it as an opportunity.

  When the storage operation is completed, the member information search unit 22 stores in the member information storage unit 23 which storage facility 30 stores the therapeutic self-cells of a certain member (step S111). Thereafter, the expense appropriation requesting means 25 performs a process for collecting the maintenance fee membership fee and a process for paying the insurance premium (step S113). That is, with respect to the membership fee, it is confirmed by receiving related information via the communication / control means 29 that the membership fee has been normally collected and that the insurance has been normally paid. The cost appropriation request means 25 periodically requests the related elements from the collected membership fee to the maintenance management expenses via the communication / control means 29 (step S115). That is, for example, a monthly payment request is made by transferring or transferring from a collection fee account to an account for maintenance costs outside the operating body of the system 100. The operating entity of the maintenance management cost account to which the maintenance management fee has been transferred by transfer or transfer performs a process to the effect that the maintenance management fee has been received (step S117). The cost allocation requesting means 25 performs a process of accumulating a part of the amount obtained by subtracting the maintenance management cost from the collected membership fee as a prepaid pool money (step S119). That is, for example, a monthly payment request is made by transferring or transferring from a collection fee account to a prepaid pool account.

  Next, the flow when a member has a failure will be described. The delivery request unit 10 is provided with a physical data monitor such as a member's heart rate, respiratory cycle, electrocardiogram pattern, voice, physical movement, etc., when a predetermined abnormality is detected in the physical data, Determination is made to activate the delivery request unit 10 (step S151). In this case, it is preferable to detect abnormalities that are particularly characteristic of the predetermined disease targeted by the present invention, such as cerebral infarction. Here, in order to prevent malfunction, when an abnormality is detected in the physical condition data, a message to that effect is once output, and then a delivery request is made on condition that no confirmation is input within a predetermined time. May be transmitted. The member can also activate the delivery request unit 10 manually. Cerebral infarction has various symptoms ranging from mild to severe depending on the location and extent of the brain where it occurs, but motor paralysis, sensory disturbance, consciousness disorder, aphasia, dementia, involuntary movement, cardiac arrest (death) ) Etc. are the main symptoms. However, in the case of cerebral infarction, it is normal that the patient's consciousness is maintained even after the occurrence of a disorder. Therefore, even if the member manually configures the delivery request unit 10 to be activated, In most cases, it is considered that the delivery request unit 10 can be activated reliably. The location reporting unit 12 included in the delivery request unit 10 acquires the location information of the member (step S153). The location information is obtained by manual input of a member, reception of a GPS signal, and reception of a signal from a terrestrial radio station such as a location information service of a mobile phone company. The ID information storage unit 11 reads the ID information stored in the ID information storage unit 11 and outputs it to the communication network 40 toward the delivery request processing unit 20 (step S155). The output is preferably performed wirelessly in response to the read radio signal. At this time, the position information is also transmitted, whereby a delivery request is transmitted from the member's side.

  The delivery request receiving means 21 receives the transmitted member ID information and position information (step S157). As a result, the delivery request processing unit 20 is activated. The member ID information and position information may be transmitted by a single data transmission / reception operation or may be transmitted by a plurality of data transmission / reception operations. Here, in order for the delivery request receiving means 21 to reliably start the delivery request processing section 20 in response to the delivery request from the delivery request section 10, first, the delivery request receiving means 21 itself responds to the received data. Must start autonomously. For this purpose, the delivery request receiving means 21 always monitors the data to be received and must discriminate the delivery request. For this purpose, the delivery request receiving means 21 is a connection part dedicated to a delivery request with a communication network (a connection part specified by an address such as a URL in the WWW, a connection part specified by an email address in an electronic mail, In a telephone line, it is considered that reception is performed only through a connection part specified by a telephone number, and the data transmitted to the address is always a delivery request. In this case, the delivery request receiving means 21 determines that there is a delivery request unit 10 that is going to issue a delivery request only by receiving the data, refers to the information of the sender of the received data, and sends the sender The transmission request signal of the member ID information and position information following the delivery request unit 10 is sent. If the communication is through the WWW, the data source information is included in the header portion of the HTTP session for transmitting data. If the communication is based on electronic mail, the sender information is included in the sender mail address. If the communication is through a telephone line, the source information can be acquired using, for example, a number display service (refer to Japanese Patent Laid-Open No. 2003-18634 for related technology).

  In response to the received transmission permission signal, the delivery request unit 10 transmits the member ID information and location information to the delivery request receiving means 21. As a result, the delivery request receiving means 21 can reliably receive a delivery request including the member ID information and location information, and issues a command to perform subsequent processing to the computer. A series of operations can be activated. In the above example of operation, the transmission request signal is used to transmit the entire delivery request by transmitting data twice or more. However, the entire information of the delivery request is transmitted to one transmission data. The entire delivery request may be transmitted by one transmission / reception operation.

  Alternatively, it is also conceivable that the delivery request receiving means 21 performs reception through a specific connection unit that is not dedicated to the delivery request. In this case, it may be possible to determine that the delivery request has been transmitted by detecting predetermined data (such as header information) that characterizes the delivery request from the data transmitted to the address.

  Based on the received ID information, the member information search means 22 searches the member information storage means 23 for the member information (step S159). That is, information about the member's treatment autologous cells is read using the ID information as a search key. Next, the agreement confirmation means 24 confirms whether or not a prior agreement for the treatment of the member has been obtained in step S103 (step S161). If a prior agreement has been obtained, the process proceeds to step S165. On the other hand, if the prior agreement has not been obtained, the member himself / herself (if the member is conscious) or the member concerned (if the member is not conscious) agrees on the treatment of the member via the communication network 40. To obtain from the member terminal 50 (step S163), and then proceeds to step S165.

  Next, the cost appropriation requesting means 25 searches the member information storing means 23 for necessary member information from the member information storing means 23 to determine whether or not there is a lack of membership fees, that is, whether or not the membership fee has been deposited. This is confirmed (step S165). Here, when there is a shortage in the membership fee, the expense allocation requesting unit 25 requests the allocation of the insufficient membership fee from the prepaid pool money. That is, a request is made to pay by transferring or transferring from the account for the prepaid pool money to the account for the collection fee (step S167). This avoids the risk of deregistration due to lack of membership fees, and members can be surely treated with autologous cells for treatment in the event of a failure, even if the membership fees are inadequate. . Thereafter, the process proceeds to step S169. On the other hand, if it is confirmed in step S165 that there is no shortage of membership fees, the process proceeds to step S169 as it is. Next, the expense appropriation request means 25 requests appropriation from the collection fee for temporary expenses such as delivery (step S169). That is, a request is made to pay by transferring or transferring from a collection fee account to an account for temporary expenses such as delivery. The operating entity of the account for temporary expenses such as delivery to which the temporary expenses such as delivery have been transferred by transfer or transfer performs processing to the effect that payment of the maintenance management expenses has been completed (step S171). Based on the contents of the insurance contract stored in the member information storage unit 23, the cost allocation requesting unit 25 determines whether insurance is applied to the treatment related to the delivery request, that is, whether the insurance is responsible or not irresponsible. Is determined (step S173). When the cost appropriation request means 25 determines that the insurance is irresponsible and the insurance money is not paid, the communication / control means 29 sends a message to that effect to the member terminal 50 via the communication network 40, and the member or member relationship The person is notified of this (step S175). This is an early notice to alert you prior to treatment, because if the insurance is not paid, the member may incur significant temporary costs. Furthermore, treatment costs that are not covered by insurance money can be used for treatment in the event of a failure because the hospital cannot confirm the willingness to pay the treatment costs by giving the member or an affiliate of the member an opportunity to indicate in advance the payment intention. This is also to reduce the risk of not being able to receive treatment with autologous cells. Thereafter, the process proceeds to step S177. On the other hand, if it is confirmed in step S173 that insurance is liable, the process proceeds directly to step S177. Next, the expense application requesting means 25 requests payment of insurance money to be applied to the medical expenses (step S177). Here, there may be a process of attaching the agreement on the side of the contractor before the request for payment. That is, the expense appropriation request means 25 transmits information specifying the member and the insurance to the computer of the insurance company, and requests that the insurance payment process be performed. The insurance company computer that has received the insurance payment request executes insurance payment processing (step S179). Requests for appropriation of expenses and payments for insurance claims may be made in bulk after the treatment with therapeutic autologous cells has begun, but in this way they are sequentially shortened after receiving a delivery request. By doing it in time, financial support can be given early to the relevant institutions, and the system can be operated very smoothly.

  Based on the location information of the member, the delivery source specifying means 26 specifies an appropriate delivery destination to which the member should receive treatment from among the locations including a plurality of pre-registered treatment facilities. The appropriate storage facility is specified as the delivery source (step S181). The detailed operation of this step is as follows. First, the delivery source specifying unit 26 specifies an appropriate delivery destination close to the member's location from among the delivery destinations registered in advance based on the location information of the member. The delivery destination is a place where treatment with autologous cells for treatment can be received, such as a predetermined hospital. The identified delivery destination is preferably transmitted to the member side such as the member terminal 50 via the communication network 40 and notified. In this way, a member who is in a troubled state can be reliably transported to a delivery destination hospital or the like to which the therapeutic self-cells are delivered. The delivery destination may be transmitted to the delivery request processing unit 20 after the member has specified. Next, the delivery source specifying means 26 specifies the storage facility 30 having the shortest distance from the storage means 30 storing the member's therapeutic self-cells to the specified delivery destination as the delivery source. More preferably, the storage facility 30 having the shortest time to reach the delivery destination, that is, the shortest delivery time is specified as the delivery source. When calculating the arrival time, it is preferable to select an appropriate delivery means 62 and consider the congestion status of the route used by the delivery means 62.

  The delivery request transfer unit 27 transmits a delivery request including member information and delivery destination information to the transfer delivery request receiving unit 31 associated with the delivery source storage facility 30 (step S183). The delivery request received by the transfer delivery request receiving unit 31 is output to the person in charge by the delivery request output unit 33 (step S185). The person in charge looks at the output delivery request, and prepares the member's treatment self-cells related to the delivery request from the storage means 34.

  The delivery request transfer unit 27 also transmits the member identification physical feature data related to the delivery request to the transfer delivery request reception unit 31 associated with the delivery source storage facility 30 (step S187). The physical characteristic data for identification received by the transfer delivery request receiving means 31 is output to the person in charge by the member identification information output means 32 (step S189). The output physical feature data for identification is a physical feature that can objectively identify a member as a member by looking at the member, such as a facial photograph image, fingerprint pattern, vein pattern, or iris pattern. Yes, by carrying the information to the delivery destination with the information, even if the member loses consciousness, the delivery destination is surely identified as the member himself (step S189). The delivery request transfer means 27 sends the transfer delivery request reception means 31 related to the storage facility 30 of the delivery source to the medical information of the member included in the member information (blood type, health check result, past illness and treatment status thereof). , Regular drugs, drug allergies, etc.).

  The delivery command means 28 specifies the delivery means 62 for delivering the therapeutic self-cells based on the member position information, and transmits a delivery command to the delivery command receiving means 61 related to the delivery means 62 (step S191). Specifically, the delivery command means 28 stores in advance the types (automobiles, motorcycles, helicopters, etc.) and location of all delivery means 62, and the delivery means 62 in the vicinity of the member based on the position information of the member. Is identified as the actual delivery. More precisely, based on the information of the delivery source and the delivery destination, the delivery means 62 that minimizes the time required to reach the delivery destination from the base (delivery processing unit 60) of the delivery means 62 via the delivery source. It is good to select. Then, a delivery command including the delivery source, delivery destination, etc. as information is transmitted to the delivery command receiving unit 61 related to the delivery unit 62 thus identified. When the delivery command is received by the delivery command receiving means 61, the driver of the delivery means 62 can know the delivery command, and operates the delivery means 62 to send the delivery request from the delivery source storage means 34 to the delivery destination. The therapeutic autologous cells are delivered (step S193). The delivery means 62 delivers the therapeutic self-cells that are stored in a frozen state in a stored state, but preferably during delivery so that they can be used for treatment at the scheduled time of arrival at the delivery destination. It may be thawed.

  In the treatment facility that has received the therapeutic self-cells, the therapeutic self-cells are thawed and returned to a state where they can be administered into the body, and then administered to the member's body by infusion or the like. As described above, the shorter the time from the occurrence of the disorder to the administration, the more remarkable the effect. Then, by appropriate and quick delivery with the support of the system 100 according to the present invention, the therapeutic self-cells can be delivered to the members at an early stage. As a result, the therapeutic effect on the members is dramatically increased.

  The communication / control unit 29 transmits the status of the delivery request processing unit 20 to the member terminal 50 via the communication network 40 (step S195). Specifically, the communication / control unit 29 determines the time when the delivery request is received, the location where the delivery request is transmitted (member position information), the storage facility specified as the delivery source, the delivery destination facility, and the delivery instruction unit 28. Identified delivery means, delivery status (preparation of departure, departure completion, movement (smooth), movement (congestion), delivery completion, etc.), departure time of delivery source, estimated arrival time at delivery destination (delivery means) It is obtained by calculation from 62 types, distance, route congestion, etc. It can also be corrected in real time by contacting from the delivery means 62.), treatment agreement, insurance coverage (responsible or irresponsible) Or the like is transmitted to the member terminal 50. FIG. 13 is an image diagram of a process notification screen for this purpose. This step operates in parallel with each of the steps described above, so that the members concerned can grasp the operation status of the delivery request processing unit 20, that is, the progress status of the delivery of the therapeutic self-cells in real time.

  Next, the operation of the therapeutic autologous cell delivery support system 101 (hereinafter abbreviated as “the present system 101”) according to another embodiment of the present invention will be described with reference to an operation flowchart. FIG. 21 is an operation flow diagram showing a typical operation relating to the always-on position notification of the therapeutic self-cell delivery support system 101, and partially replaces the operation flow of FIG. The system 101 performs substantially the same operation as the system 100, except that the operations of steps S201 to S209 shown in FIG. 21 are performed instead of the operations of steps S151 to S155 in the system 100. Therefore, the operation of the difference will be described.

  The member always carries the location reporting means 71 at all times. The always-on location reporting unit 71 constantly reports the member ID information and location information to the always-on location reporting unit 72 via the communication network 40 (step S201). The position comparison means 73 compares the position information of the member with the position information of a facility such as a hospital stored in the facility position storage means 74 for the presence / absence of the facility corresponding to the position information of the member, and the member stores the position information. It is confirmed by judging whether it is in the designated facility (step S203). If there is no facility, the process returns to step S201. If there is a facility, the member may be in an emergency, so proceed to the next step to further confirm whether a delivery request is required. In the next step, the position comparison means 73 determines the necessity of delivery based on the secondary index (step S205). The secondary index can be a professional index, time, etc. according to the specialty of the facility. The higher the professional index of the facility, the higher the probability of determining that delivery is necessary. Further, if the time is late night, early morning, etc., the probability of determining that delivery is necessary is increased. If it is determined that the delivery is unnecessary, the process returns to step S201. If it is determined that the delivery is necessary, the process proceeds to the next step in order to confirm whether or not the delivery request is actually issued. In the next step, the delivery request confirmation unit 75 confirms whether or not to issue a delivery request (step S207). Confirmation of whether or not to issue a delivery request can be made to the person himself / herself, the person in charge at the facility, the operator on the management entity side, or the like. The person can be confirmed by sending a call or e-mail based on a telephone number or e-mail address registered in advance in the member information. For the person in charge of the facility, the facility location storage means 74 can store the telephone number or mail address of each facility, and by reading it, the telephone or mail can be transmitted for confirmation. . As a result, even in a situation where the member cannot respond, it is possible to grasp the situation reliably, and to appropriately check whether or not to issue a delivery request. For the operator on the operating subject side, the delivery request confirmation means 75 outputs the member location information and accepts the delivery request input based on the operator's judgment, so that the delivery request can be confirmed. Here, the operator can confirm by contacting the person in charge at the facility. If it is confirmed that no delivery request is made, the process returns to step S201. If it is confirmed that a delivery request is made, the process proceeds to the next step.

  In the next step, the delivery request confirmation unit 75 issues a delivery request to the delivery request processing unit 20 through the communication network 40 (step S209). The delivery request can also include information on the facility determined to have entered the member, such as the name of the facility, a telephone number, and a map of the surrounding area, so that the delivery means 62 can smoothly deliver the therapeutic self-cells. As is done, such information of the delivery destination can also be communicated. As a result, a request for delivery of therapeutic autologous cells to the member is issued. Thereafter, the same steps as those after step S157 of the system 100 proceed.

  According to this embodiment, even if a member does not voluntarily issue a delivery request, the member's position is monitored to autonomously determine whether the delivery of therapeutic self-cells to the member is necessary. Can do.

  Note that the location information of a member that is constantly notified does not have to be direct location information, and may be location specification information that can indirectly specify location information. The position specifying information may be, for example, receiver specifying information indicating which receiver has previously received a signal from the member's constant position reporting means 71 by installing a receiver in the facility in advance. In this case, since the location of the facility where the receiver is installed is known in advance, by receiving in advance the receiver identification information and the location information of the facility, reception of which receiver has received it. This is because if the machine identification information is known, the facility where the receiver is installed can be identified.

1 is a system configuration diagram showing a configuration of a therapeutic self-cell delivery support system 100. FIG. It is an operation | movement flowchart which shows the typical operation | movement of the therapeutic self-cell delivery assistance system 100. FIG. FIG. 3 is an operation flow diagram showing a typical operation of the therapeutic self-cell delivery support system 100, which is a continuation of FIG. FIG. 4 is an operation flow diagram showing a typical operation of the therapeutic self-cell delivery support system 100 and is a continuation of FIG. 3. FIG. 5 is an operation flow diagram showing a typical operation of the therapeutic self-cell delivery support system 100 and is a continuation of FIG. 4. It is an image figure of a member registration screen. It is an image figure of a membership fee collection method selection screen. It is an image figure of an insurance subscription screen. It is an image figure of an explanation matter confirmation screen. It is an image figure of a prior agreement confirmation screen. It is an image figure of a questionnaire screen. It is an image figure of a life advice screen. It is an image figure of a process notification screen. It is an image figure of an insurance design example display screen (1). It is an image figure of an insurance design example display screen (2). It is an MRI image which shows as a picture the result of intravenously administering mesenchymal stem cells (1 × 10 ⁶ cells) to severe cerebral infarction (rat middle cerebral artery permanent occlusion model). It is a graph which shows as a volume of a cerebral infarction area | region the result of intravenously administering a mesenchymal stem cell (1 × 10 ⁶ cell) to severe cerebral infarction (rat middle cerebral artery permanent occlusion model). It is a graph which shows the result of administering mesenchymal stem cells (1 × 10 ⁶ cells) intravenously to severe cerebral infarction (rat middle cerebral artery permanent occlusion model) as a change in survival rate after the occurrence of injury. It is a system block diagram showing the structure of the therapeutic self-cell delivery assistance system 101 which concerns on other embodiment of this invention. It is an operation | movement flowchart which shows operation | movement until the storage to the storage facility 30 of the treatment self-cell in the treatment self-cell delivery support system 100 and 101. FIG. FIG. 4 is an operation flow diagram showing a typical operation related to a continuous position notification of the therapeutic self-cell delivery support system 101, partially replacing the operation flow of FIG.

Explanation of symbols

DESCRIPTION OF SYMBOLS 10 Delivery request part 11 ID information storage means 12 Location report means 20 Delivery request processing part 21 Delivery request reception means 22 Member information search means 23 Member information storage means 24 Agreement confirmation means 25 Cost appropriation request means 26 Delivery source identification means 27 Delivery request Transfer means 28 Delivery instruction means 29 Communication / control means 30 Storage facility 31 Transfer delivery request reception means 32 Member identification information output means 33 Delivery request output means 34 Storage means 40 Communication network 50 Member terminal 60 Delivery processing section 61 Delivery instruction reception means 62 Delivery means 71 Constant position notification means 72 Constant position reception means 73 Position comparison means 74 Facility position storage means 75 Delivery request confirmation means 100 Treatment self-cell delivery support system 101 Treatment self-cell delivery support system

Claims (46)

Distinguish treatment self-cells for in vivo damage site regeneration treatment by in vivo administration to the member who has been collected from the body of the member and grown to at least the amount necessary for treatment after collection for each member. Storage means for storing;
Member information storage functioned by a computer that stores ID information uniquely corresponding to a member in which the therapeutic self-cells are stored in the storage means and member information of the member including at least a member name in association with each other. Means,
A delivery request reception functioned by a computer that receives, via a communication network, a delivery request including ID information of a member who needs delivery to the delivery destination of the therapeutic self-cells for treatment and location information of the member. Means,
A member information search means that is made to function by a computer, searches for member information of the member from the member information storage means based on the ID information included in the delivery request received by the delivery request receiving means;
Self-treatment for medical treatment, comprising: delivery request output means for outputting member information searched by the member information search means and position information of the member for outputting information related to the storage means Cell delivery support system. A plurality of the storage means and the delivery request output means exist in geographically different positions,
Based on the location information of the member included in the delivery request received by the delivery request receiving means, an appropriate delivery destination to which the member should receive treatment is identified from among locations including a plurality of pre-registered treatment facilities. , A delivery source specifying means operable by a computer to specify an appropriate storage means among the plurality of storage means as a delivery source;
Delivery request output related to the storage means of the delivery source specified by the delivery source specifying means with the member information at least including the member name searched by the member information search means and the delivery destination information regarding the specified delivery destination A delivery request transfer means that is made to function by a computer that transmits to the means, and the delivery request output means outputs member information and delivery destination information sent by the delivery request transfer means, The therapeutic self-cell delivery support system according to claim 1.   The therapeutic means according to claim 2, wherein the storage means specified by the delivery source specifying means as a delivery source is a storage means at a geographical position where delivery time to the specified delivery destination is the shortest. Autologous cell delivery support system.   4. An ID information storage unit for recording the ID information of the member and transmitting the ID information to the delivery request receiving unit via the communication network. The therapeutic self-cell delivery support system according to Item 1.   5. The therapeutic self-cell delivery support system according to claim 4, wherein the ID information storage means transmits the ID information to the communication network in accordance with a manual operation of a member.   The ID information storage means monitors physical data including at least one of a heart rate, a respiratory cycle, an electrocardiogram pattern, a voice, and a body motion, and when an abnormality is detected in the physical data, the ID information is stored in the communication network. 5. The therapeutic self-cell delivery support system according to claim 4, wherein:   The ID information storage means once outputs an abnormality when abnormality is detected in the physical condition data, and then transmits the ID information on the condition that a confirmation input is not made within a predetermined time. 7. The therapeutic self-cell delivery support system according to claim 6, wherein the system is transmitted to a network.   The therapeutic self-cell delivery support system according to any one of claims 1 to 7, wherein the ID information storage means is connected to the communication network by radio.   The position reporting means for specifying the location of the member and transmitting the specified location to the delivery request receiving means via the communication network as the location information of the member. The therapeutic self-cell delivery support system according to any one of the above.   The therapeutic self-cell delivery support system according to claim 9, wherein the location reporting means is connected to the communication network by radio.   11. The therapeutic self-cell delivery support system according to claim 10, wherein the location reporting unit specifies the location of the member by GPS.   11. The therapeutic self-cell delivery support system according to claim 10, wherein the location reporting means identifies the location of the member by receiving radio waves from ground radio equipment.   The member information stored by the member information storage means includes physical feature data for identification including at least one of a face photograph image, a fingerprint pattern, a vein pattern, and an iris pattern. 13. The therapeutic self-cell delivery support system according to any one of 1 to 12. The apparatus further comprises an agreement confirmation means that is operated by a computer for confirming whether or not there is a prior agreement on the use of therapeutic autologous cells from the member, and the delivery request output means is a prior agreement of the member If there is, the member's member information and location information will be output, and if there is no prior agreement of the member, the member will be subject to confirmation of the agreement from the member or a related party of the member. 14. The therapeutic self-cell delivery support system according to any one of claims 1 to 13, wherein the member information and the position information are output.   Based on the position information of the member, a delivery means for delivering the therapeutic self-cells is identified from a plurality of delivery means existing at geographically different positions, and a delivery command is transmitted to the identified delivery means 15. The therapeutic self-cell delivery support system according to any one of claims 1 to 14, further comprising a delivery command means.   Delivery request reception time, location information included in delivery request, storage means specified as delivery source, specified delivery destination, specified delivery means, delivery status, delivery source departure time, arrival at delivery destination Process notification means for transmitting at least one of scheduled time, presence / absence of treatment agreement, presence / absence of insurance coverage to the member who issued the delivery request or a predetermined related party of the member via the communication network; 16. The therapeutic self-cell delivery support system according to claim 15, further comprising:   Confirmation of enrollment intention is confirmed through the communication network, member information including at least the member name is acquired through the communication network, an answer to a predetermined questionnaire is input through the communication network, and feedback based on the answer result of the questionnaire is The therapeutic self-cell delivery support system according to any one of claims 1 to 16, further comprising: a membership reception means that is provided via a communication network and is made to function by a computer.   The delivery request receiving means has a dedicated connection part with a communication network for the delivery request, and judges that the delivery request has been transmitted by receiving data. 18. The therapeutic self-cell delivery support system according to any one of 1 to 17.   The delivery request receiving means has a connection unit with the communication network, and determines that the delivery request has been transmitted by detecting predetermined data characterizing the delivery request from the received data. The therapeutic self-cell delivery support system according to any one of claims 1 to 17.   The therapeutic autologous cells include cerebral infarction, cerebral hemorrhage, spinal cord injury, myocardial infarction, stroke including subarachnoid hemorrhage, central and peripheral demyelinating diseases, central and peripheral degenerative diseases, brain tumors, dementia At least one of higher dysfunction, mental illness, epilepsy, traumatic nervous system disease including head injury, brain contusion and spinal cord injury, inflammatory disease, and brain cell damaging infectious disease including Jacob disease 20. The therapeutic self-cell delivery support system according to any one of claims 1 to 19, wherein the system is used for treatment.   21. The therapeutic self-cell delivery support system according to claim 1, wherein the therapeutic self-cells are mesenchymal stem cells collected in an undifferentiated state from a member's body. .   21. The therapeutic autologous cell according to any one of claims 1 to 20, wherein the mesenchymal stem cell collected in an undifferentiated state from a member's body is subjected to genetic manipulation. Self-cell delivery support system for treatment.   The treatment according to any one of claims 1 to 20, wherein the therapeutic autologous cells are those obtained by inducing differentiation of mesenchymal stem cells collected in an undifferentiated state from a member's body. Self-cell delivery support system. The therapeutic self-cell delivery support system according to any one of claims 1 to 23,
A financial system for supporting cell delivery for treatment, comprising: a computer-operated cost appropriation requesting means for requesting appropriation to a cost from the collected money collected from the member,
The cost appropriation request means periodically requests appropriation for maintenance costs that occur regularly, and requests appropriation for temporary costs such as delivery accompanying the delivery request in response to the delivery request. A therapeutic self-cell delivery support financial system characterized by:   25. The therapeutic self-cell delivery support finance according to claim 24, wherein the cost appropriation requesting unit requests the appropriation from the collected fee for the treatment cost related to the delivery request in response to the delivery request. system.   The cost appropriation requesting means responds to the delivery request by applying appropriation from the collection fee to the treatment cost related to the delivery request as insurance money expenditure from an insurance with at least a part of the collection fee as an insurance premium. 25. The therapeutic self-cell delivery support financial system according to claim 24.   If the cost appropriation requesting unit requests the payment of insurance money to be applied to the treatment cost associated with the delivery request, whether the insurance contract is liable or irresponsible based on the insurance contract and the reason for the delivery request 27. The therapeutic self-cell delivery support finance according to claim 26, wherein, in the case of being irresponsible, the member or the related party is notified of the irresponsibility through the communication network. system.   An insurance subscription acceptance means operable by a computer for confirming the intention to join the insurance through the communication network and acquiring at least a part of predetermined information necessary for insurance purchase through the communication network; 28. The therapeutic self-cell delivery support financial system according to claim 26 or 27.   Insurance design providing means for transmitting, through the communication network, a typical design including a collection including insurance premiums, a cost when a delivery request is made, and an insurance premium for each of when the insurance is enrolled and when not enrolled, The therapeutic self-cell delivery support financial system according to any one of claims 26 to 28, further comprising: Distinguish treatment self-cells for in vivo damage site regeneration treatment by in vivo administration to the member who has been collected from the body of the member and grown to at least the amount necessary for treatment after collection for each member. Storing in a storage means;
Member information storage implemented by a computer that stores ID information uniquely corresponding to a member in which the therapeutic self-cells are stored in the storage means and member information of the member including at least a member name in association with each other. And the steps
A computer-implemented delivery request reception for receiving, via a communication network, a delivery request including ID information of a member who requires delivery of the therapeutic self-cells to a delivery destination for treatment and location information of the member. And the steps
Member information implemented by a computer that retrieves member information of the member from member information stored in the member information storage step based on ID information included in the delivery request received in the delivery request reception step Search step and
And a delivery request output step for outputting member information retrieved by the member information retrieval step and location information of the member for outputting information related to the storage means. Auto cell delivery support method. Respective steps included in the therapeutic self-cell delivery support method according to claim 30,
A computer-implemented cost appropriation requesting method for requesting appropriation of costs from the collected money collected from the member, comprising:
The cost allocation request step periodically requests allocation to maintenance costs that occur regularly, and allocates temporary costs, such as delivery, that accompany the delivery request according to the delivery request. A self-cell delivery support financial method for treatment, characterized by claiming.   32. The therapeutic self-cell delivery support according to claim 31, wherein the cost appropriation requesting step requests the appropriation from the collection fee for the treatment cost related to the delivery request in response to the delivery request. Financial method.   The cost appropriation requesting step is to respond to the delivery request as appropriation from the collected money for the treatment cost related to the delivery request as an insurance money expenditure from an insurance with at least a part of the collected money as an insurance premium. 33. The therapeutic self-cell delivery support financial method according to claim 32, characterized by: Distinguish treatment self-cells for in vivo damage site regeneration treatment by in vivo administration to the member who has been collected from the body of the member and grown to at least the amount necessary for treatment after collection for each member. Storage means for storing;
Member information storage functioned by a computer that stores ID information uniquely corresponding to a member in which the therapeutic self-cells are stored in the storage means and member information of the member including at least a member name in association with each other. Means,
A computer that receives, via a communication network, a delivery request including ID information of a member who needs delivery of the therapeutic self-cells to a delivery destination for treatment and location specifying information for specifying the location of the member. A delivery request receiving means that is operated by:
A member information search means that is made to function by a computer, searches for member information of the member from the member information storage means based on the ID information included in the delivery request received by the delivery request receiving means;
A delivery request output means for outputting member information searched by the member information search means and location specifying information of the member for outputting information related to the storage means; Autologous cell delivery support system.   The therapeutic self-cell delivery support system according to claim 34, further comprising position specifying means for obtaining the position information based on the position specifying information. A plurality of the storage means and the delivery request output means exist in geographically different positions,
Based on the position information of the member specified by the position specifying means, an appropriate delivery destination to which the member should receive treatment is specified from a place including a plurality of pre-registered treatment facilities, and the plurality of storage means A delivery source identification means operable by a computer to identify an appropriate storage means as a delivery source;
Delivery request output related to the storage means of the delivery source specified by the delivery source specifying means with the member information at least including the member name searched by the member information search means and the delivery destination information regarding the specified delivery destination A delivery request transfer means that is made to function by a computer that transmits to the means, and the delivery request output means outputs member information and delivery destination information sent by the delivery request transfer means, 36. The therapeutic self-cell delivery support system according to claim 35.   37. The therapeutic device according to claim 36, wherein the storage means specified as the delivery source by the delivery source specifying means is a storage means at a geographical position where delivery time to the specified delivery destination is the shortest. Autologous cell delivery support system.   The ID information storage means for recording the ID information of the member and transmitting the ID information to the delivery request receiving means via the communication network, further comprising: an ID information storage means. The therapeutic self-cell delivery support system according to Item 1.   39. The therapeutic self-cell delivery support system according to claim 38, wherein the ID information storage means is an external memory element that stores the ID information.   The external memory element further stores an ID information transmission program for transmitting the ID information of a member to the delivery request receiving means via the communication network when the ID information storage means is connected to a computer terminal. 40. The therapeutic self-cell delivery support system according to claim 39.   The external memory device receives position specifying information for specifying the position of the computer terminal as the position of the member when the ID information storage means is connected to the computer terminal via the communication network. 40. The therapeutic self-cell delivery support system according to claim 39, further storing a position specification information transmission program for transmission to the medical device.   The position information transmission program prompts the operator of the computer terminal on which the position information is operating to input the position, and transmits the input information to the delivery request receiving means as position specifying information. Cell delivery support system.   43. The therapeutic self-cell delivery support system according to any one of claims 39 to 42, wherein the external memory device is in the form of a USB key. Distinguish treatment self-cells for in vivo damage site regeneration treatment by in vivo administration to the member who has been collected from the member's body and grown to at least the amount necessary for treatment after collection for each member. Storage means for storing;
Member information storage functioned by a computer that stores ID information uniquely corresponding to a member in which the therapeutic self-cells are stored in the storage means and member information of the member including at least a member name in association with each other. Means,
A constant position receiving means that is made to function by a computer and that receives position specifying information for specifying the position of a member constantly via a communication network;
Facility location storage means for storing the facility and location information of the facility in association with each other;
Position comparing means for comparing the position information specified from the received position specifying information and the position information stored in the position storage means to confirm the presence or absence of a facility corresponding to the position information of the member;
A delivery request transmitting means for issuing a delivery request including the ID information and location information of the member when the location comparing means determines that there is a facility corresponding to the location information of the member;
A member information search means that is made to function by a computer, acquires ID information issued by the delivery request transmission, and searches the member information storage means from the member information storage means based on the ID information;
Self-treatment for medical treatment, comprising: delivery information output means for outputting member information searched by the member information search means and position information of the member for outputting information related to the storage means Cell delivery support system.   45. The therapeutic self-cell delivery support system according to claim 44, wherein the delivery request transmission means confirms whether or not to issue a delivery request to the member before issuing the delivery request.   The delivery request transmission means determines whether or not to issue the delivery request based on a secondary indicator including at least one of a facility specialty indicator and time before issuing the delivery request. 46. The therapeutic self-cell delivery support system according to claim 45.

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