JP2015160820A - 慢性腎障害治療のための多能性幹細胞 - Google Patents

慢性腎障害治療のための多能性幹細胞 Download PDF

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Publication number
JP2015160820A
JP2015160820A JP2014035931A JP2014035931A JP2015160820A JP 2015160820 A JP2015160820 A JP 2015160820A JP 2014035931 A JP2014035931 A JP 2014035931A JP 2014035931 A JP2014035931 A JP 2014035931A JP 2015160820 A JP2015160820 A JP 2015160820A
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Prior art keywords
cells
cell
negative
muse
pluripotent stem
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Japanese (ja)
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JP2015160820A5 (enExample
Inventor
正順 吉田
Masayori Yoshida
正順 吉田
真理 出澤
Mari Idesawa
真理 出澤
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Tohoku University NUC
Clio Inc
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Tohoku University NUC
Clio Inc
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Priority to JP2014035931A priority Critical patent/JP2015160820A/ja
Priority to US14/695,872 priority patent/US20160058800A1/en
Publication of JP2015160820A publication Critical patent/JP2015160820A/ja
Priority to US15/413,129 priority patent/US10293003B2/en
Publication of JP2015160820A5 publication Critical patent/JP2015160820A5/ja
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48Reproductive organs
    • A61K35/54Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
    • A61K35/545Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2014035931A 2014-02-26 2014-02-26 慢性腎障害治療のための多能性幹細胞 Pending JP2015160820A (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2014035931A JP2015160820A (ja) 2014-02-26 2014-02-26 慢性腎障害治療のための多能性幹細胞
US14/695,872 US20160058800A1 (en) 2014-02-26 2015-04-24 Pluripotent stem cell for treatment of chronic kidney disease
US15/413,129 US10293003B2 (en) 2014-02-26 2017-01-23 Multilineage-differentiating stress enduring (MUSE) cells for treatment of chronic kidney disease

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2014035931A JP2015160820A (ja) 2014-02-26 2014-02-26 慢性腎障害治療のための多能性幹細胞

Related Child Applications (1)

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JP2018126976A Division JP7072777B2 (ja) 2018-07-03 2018-07-03 慢性腎障害治療のための多能性幹細胞

Publications (2)

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JP2015160820A true JP2015160820A (ja) 2015-09-07
JP2015160820A5 JP2015160820A5 (enExample) 2017-02-09

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JP2014035931A Pending JP2015160820A (ja) 2014-02-26 2014-02-26 慢性腎障害治療のための多能性幹細胞

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US (2) US20160058800A1 (enExample)
JP (1) JP2015160820A (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018162308A (ja) * 2018-07-03 2018-10-18 株式会社生命科学インスティテュート 慢性腎障害治療のための多能性幹細胞
WO2021085639A1 (ja) * 2019-10-31 2021-05-06 株式会社生命科学インスティテュート 多能性幹細胞による間質性膀胱炎の治療
JP2023001294A (ja) * 2016-07-01 2023-01-04 国立大学法人東北大学 臓器線維症の予防または治療剤

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107050050B (zh) * 2017-04-19 2020-06-19 樊均明 一种肾小球和肾小管复合损伤的猕猴慢性肾病模型的建立方法
SG11201912831TA (en) * 2017-06-20 2020-01-30 Univ Nagoya Nat Univ Corp Amelioration and treatment of brain disorder resulting from fetal growth retardation using pluripotent stem cells
EP4061400A4 (en) * 2019-11-20 2024-01-10 Cornell University Generation of kidney glomerular specific endothelial cells and methods of use

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003013588A1 (en) * 2001-08-08 2003-02-20 Kaken Pharmaceutical Co., Ltd. Kidney regeneration material comprising cells and cell growth factor
JP2012100662A (ja) * 2011-12-05 2012-05-31 Sapporo Medical Univ 細胞増殖方法ならびに組織の修復および再生のための医薬
JP2012139246A (ja) * 2009-07-15 2012-07-26 Mari Idesawa 生体組織から単離できる多能性幹細胞
WO2014027684A1 (ja) * 2012-08-17 2014-02-20 株式会社Clio 心筋梗塞の修復再生を誘導する多能性幹細胞

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2521217C (en) * 2003-04-01 2013-05-14 United States Of America Department Of Veteran's Affairs Stem-cell, precursor cell, or target cell-based treatment of multi-organ failure and renal dysfunction

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003013588A1 (en) * 2001-08-08 2003-02-20 Kaken Pharmaceutical Co., Ltd. Kidney regeneration material comprising cells and cell growth factor
JP2012139246A (ja) * 2009-07-15 2012-07-26 Mari Idesawa 生体組織から単離できる多能性幹細胞
JP2012100662A (ja) * 2011-12-05 2012-05-31 Sapporo Medical Univ 細胞増殖方法ならびに組織の修復および再生のための医薬
WO2014027684A1 (ja) * 2012-08-17 2014-02-20 株式会社Clio 心筋梗塞の修復再生を誘導する多能性幹細胞

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
INFRAMMATION AND REGENERATION, 2010, VOL.30, NO.4, P.360, JPN6017032530, ISSN: 0003914535 *
MOL. CELL BIOCHEM., 2012, VOL.368, PP.137-145, JPN6017032529, ISSN: 0003914534 *
PERIPHERAL NERVE, 2012, VOL.23, NO.2, PP.135-139, JPN6017034978, ISSN: 0003914537 *
東北医学雑誌, 2013, VOL.125, NO.1, PP.107-109, JPN6017032532, ISSN: 0003914536 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023001294A (ja) * 2016-07-01 2023-01-04 国立大学法人東北大学 臓器線維症の予防または治療剤
JP2018162308A (ja) * 2018-07-03 2018-10-18 株式会社生命科学インスティテュート 慢性腎障害治療のための多能性幹細胞
JP7072777B2 (ja) 2018-07-03 2022-05-23 株式会社生命科学インスティテュート 慢性腎障害治療のための多能性幹細胞
WO2021085639A1 (ja) * 2019-10-31 2021-05-06 株式会社生命科学インスティテュート 多能性幹細胞による間質性膀胱炎の治療
JPWO2021085639A1 (enExample) * 2019-10-31 2021-05-06
US12491211B2 (en) 2019-10-31 2025-12-09 Tohoku University Therapy for interstitial cystitis by pluripotent stem cells

Also Published As

Publication number Publication date
US10293003B2 (en) 2019-05-21
US20170128498A1 (en) 2017-05-11
US20160058800A1 (en) 2016-03-03

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