JP2015127308A5 - - Google Patents
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- Publication number
- JP2015127308A5 JP2015127308A5 JP2013273140A JP2013273140A JP2015127308A5 JP 2015127308 A5 JP2015127308 A5 JP 2015127308A5 JP 2013273140 A JP2013273140 A JP 2013273140A JP 2013273140 A JP2013273140 A JP 2013273140A JP 2015127308 A5 JP2015127308 A5 JP 2015127308A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- combination
- prok1
- agent
- vegf antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108090001123 antibodies Proteins 0.000 claims 6
- 102000004965 antibodies Human genes 0.000 claims 6
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 201000011231 colorectal cancer Diseases 0.000 claims 2
- ZROHGHOFXNOHSO-BNTLRKBRSA-L (1R,2R)-cyclohexane-1,2-diamine;oxalate;platinum(2+) Chemical group [H][N]([C@@H]1CCCC[C@H]1[N]1([H])[H])([H])[Pt]11OC(=O)C(=O)O1 ZROHGHOFXNOHSO-BNTLRKBRSA-L 0.000 claims 1
- GHASVSINZRGABV-UHFFFAOYSA-N 5-flurouricil Chemical compound FC1=CNC(=O)NC1=O GHASVSINZRGABV-UHFFFAOYSA-N 0.000 claims 1
- 108010022830 Cetuximab Proteins 0.000 claims 1
- 229960002949 Fluorouracil Drugs 0.000 claims 1
- UWKQSNNFCGGAFS-XIFFEERXSA-N Irinotecan Chemical compound C1=C2C(CC)=C3CN(C(C4=C([C@@](C(=O)OC4)(O)CC)C=4)=O)C=4C3=NC2=CC=C1OC(=O)N(CC1)CCC1N1CCCCC1 UWKQSNNFCGGAFS-XIFFEERXSA-N 0.000 claims 1
- 108010061219 Panitumumab Proteins 0.000 claims 1
- 239000002257 antimetastatic agent Substances 0.000 claims 1
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 229960005395 cetuximab Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229960004768 irinotecan Drugs 0.000 claims 1
- 229960001756 oxaliplatin Drugs 0.000 claims 1
- 229960001972 panitumumab Drugs 0.000 claims 1
Claims (4)
- 抗PROK1抗体と抗VEGF抗体とを組み合わせてなる、大腸癌の治療剤。
- 抗PROK1抗体と抗VEGF抗体とを組み合わせてなる、大腸癌における転移抑制剤。
- 抗PROK1抗体と抗VEGF抗体とを含有する合剤である、請求項１または２に記載の剤。
- イリノテカン、セツキシマブ、5-フルオロウラシル、オキサリプラチン及びパニツムマブから選択される少なくとも１種の抗癌剤を、さらに組み合わせてなる、請求項１〜３のいずれか一項に記載の剤。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013273140A JP6320040B2 (ja) | 2013-12-27 | 2013-12-27 | 抗ｐｒｏｋ１抗体及び抗ｖｅｇｆ抗体併用による大腸癌の治療 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013273140A JP6320040B2 (ja) | 2013-12-27 | 2013-12-27 | 抗ｐｒｏｋ１抗体及び抗ｖｅｇｆ抗体併用による大腸癌の治療 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015127308A JP2015127308A (ja) | 2015-07-09 |
| JP2015127308A5 true JP2015127308A5 (ja) | 2017-02-09 |
| JP6320040B2 JP6320040B2 (ja) | 2018-05-09 |
Family
ID=53837492
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013273140A Active JP6320040B2 (ja) | 2013-12-27 | 2013-12-27 | 抗ｐｒｏｋ１抗体及び抗ｖｅｇｆ抗体併用による大腸癌の治療 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP6320040B2 (ja) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3175277A1 (en) * | 2020-03-12 | 2021-09-16 | Toray Industries, Inc. | Medicament for treatment and/or prevention of cancer |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020172678A1 (en) * | 2000-06-23 | 2002-11-21 | Napoleone Ferrara | EG-VEGF nucleic acids and polypeptides and methods of use |
| JP2003292455A (ja) * | 2002-02-04 | 2003-10-15 | Takeda Chem Ind Ltd | 血管新生阻害剤 |
-
2013
- 2013-12-27 JP JP2013273140A patent/JP6320040B2/ja active Active
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