JP2015074641A5 - - Google Patents
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- Publication number
- JP2015074641A5 JP2015074641A5 JP2013213155A JP2013213155A JP2015074641A5 JP 2015074641 A5 JP2015074641 A5 JP 2015074641A5 JP 2013213155 A JP2013213155 A JP 2013213155A JP 2013213155 A JP2013213155 A JP 2013213155A JP 2015074641 A5 JP2015074641 A5 JP 2015074641A5
- Authority
- JP
- Japan
- Prior art keywords
- active agent
- mcg
- biodegradable
- matrix
- block copolymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000013543 active substance Substances 0.000 claims 13
- 239000011159 matrix material Substances 0.000 claims 7
- 239000004372 Polyvinyl alcohol Substances 0.000 claims 3
- 229920001400 block copolymer Polymers 0.000 claims 3
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 3
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 3
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 3
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims 3
- 229920002451 polyvinyl alcohol Polymers 0.000 claims 3
- 229920000954 Polyglycolide Polymers 0.000 claims 2
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims 2
- 229920002988 biodegradable polymer Polymers 0.000 claims 2
- 239000004621 biodegradable polymer Substances 0.000 claims 2
- 238000012377 drug delivery Methods 0.000 claims 2
- 239000002243 precursor Substances 0.000 claims 2
- 229920002785 Croscarmellose sodium Polymers 0.000 claims 1
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims 1
- 239000002202 Polyethylene glycol Substances 0.000 claims 1
- 210000005252 bulbus oculi Anatomy 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 239000001768 carboxy methyl cellulose Substances 0.000 claims 1
- 230000001886 ciliary effect Effects 0.000 claims 1
- 229920001577 copolymer Polymers 0.000 claims 1
- 229960001681 croscarmellose sodium Drugs 0.000 claims 1
- 235000010947 crosslinked sodium carboxy methyl cellulose Nutrition 0.000 claims 1
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 claims 1
- 229960003957 dexamethasone Drugs 0.000 claims 1
- 229920003063 hydroxymethyl cellulose Polymers 0.000 claims 1
- 229940031574 hydroxymethyl cellulose Drugs 0.000 claims 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims 1
- 238000011065 in-situ storage Methods 0.000 claims 1
- 239000008188 pellet Substances 0.000 claims 1
- 229920001606 poly(lactic acid-co-glycolic acid) Polymers 0.000 claims 1
- 229920001223 polyethylene glycol Polymers 0.000 claims 1
- 239000004633 polyglycolic acid Substances 0.000 claims 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013213155A JP6543431B2 (ja) | 2013-10-10 | 2013-10-10 | 眼内薬物送達デバイスおよび付随する方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013213155A JP6543431B2 (ja) | 2013-10-10 | 2013-10-10 | 眼内薬物送達デバイスおよび付随する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015074641A JP2015074641A (ja) | 2015-04-20 |
| JP2015074641A5 true JP2015074641A5 (https=) | 2016-11-17 |
| JP6543431B2 JP6543431B2 (ja) | 2019-07-10 |
Family
ID=52999772
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013213155A Active JP6543431B2 (ja) | 2013-10-10 | 2013-10-10 | 眼内薬物送達デバイスおよび付随する方法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP6543431B2 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018125930A1 (en) * | 2016-12-27 | 2018-07-05 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0720859B2 (ja) * | 1985-02-07 | 1995-03-08 | 武田薬品工業株式会社 | マイクロカプセルの製造法 |
| US5869079A (en) * | 1995-06-02 | 1999-02-09 | Oculex Pharmaceuticals, Inc. | Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents |
| JP2002531217A (ja) * | 1998-12-04 | 2002-09-24 | チャンドラシェカー ピー． パサック， | 生体適合性架橋ポリマー |
| AU2002236495B2 (en) * | 2000-11-29 | 2006-05-11 | Allergan, Inc. | Intraocular implants for preventing transplant rejection in the eye |
| US8685435B2 (en) * | 2004-04-30 | 2014-04-01 | Allergan, Inc. | Extended release biodegradable ocular implants |
| TWI369218B (en) * | 2004-12-14 | 2012-08-01 | Novartis Ag | In situ forming implant for animals |
| ATE454908T1 (de) * | 2005-09-21 | 2010-01-15 | Surmodics Inc | In situ okklusionszusammensetzungen mit natürlichen biologisch abbaubaren polysacchariden |
| BRPI0604577B8 (pt) * | 2006-08-31 | 2021-05-25 | Univ Minas Gerais | formulação farmacêutica para administração intraocular de fármacos e processo de obtenção |
-
2013
- 2013-10-10 JP JP2013213155A patent/JP6543431B2/ja active Active
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