JP2015054203A - Medical double-chamber container - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a medical double-chamber container capable of preventing erroneous dosing of a medication before mixing, facilitating the mixing by only one operation of depressing one medication chamber, having such shock resistance as to be scarcely torn even when falling, and inhibiting a pinhole from being formed on an outer wrapper.SOLUTION: The medical double-chamber container includes: a compartment weak seal part 13 for communicably comparting the container into a plurality of medication chambers 12A and 12B; a medication discharge port 14 provided at the second medication chamber 12B; and an inflow-prevention weak seal part 15 for temporarily preventing inflow of the medication from the second medication chamber 12B to the port 14 and facing the compartment weak seal part 13. The double-chamber container further includes a pair of recessed seal parts 16 that are continuously provided from facing peripheral seal parts and are recessed inward in the medical double-chamber container. The compartment weak seal part 13 is configured to connect bottom parts 16a of the recessed seal parts 16, and each recessed seal part 16 has a notch K at an area of an inside part thereof.

Description

  The present invention relates to a medical multi-chamber container.

  Conventionally, a medical multi-chamber container made of a flexible film containing a medicine in a plurality of medicine chambers partitioned by a partition wall provided in the container has been used as a medicine container for infusion treatment in the medical field. ing. Examples of combinations of a plurality of drugs include amino acid and glucose infusion solutions, antibiotics and dissolved solutions thereof, and the like, which may cause deterioration over time when mixed and stored. The partition walls of the medical multi-chamber container are used as weakly sealed portions that are sealed so that the inner surfaces of the containers can be peeled from each other.

When performing a drip treatment using a medical multi-chamber container, the weak seal part is peeled off by applying an internal pressure to the medicine by pressing one chamber containing the liquid medicine before use. And the medicine chambers are communicated with each other to mix a plurality of medicines aseptically in a medical multi-chamber container. The mixed medicine is discharged from the outlet of the container via the needle and tube of the infusion set, and is administered to the patient. In the case of drip treatment using a medical multi-chamber container that mixes and uses a plurality of drugs in this way, an unmixed drug is infused without accidentally destroying the partition wall of the medical multi-chamber container. It has been pointed out that this could happen.
Therefore, in order to prevent the pre-mixing medicine from being administered, a technology including a weak seal portion for inhibiting communication between the medicine chamber and the discharge port is disclosed (for example, Patent Document 1). reference).

In the technique described in Patent Document 1, the partition weak seal section that partitions the first and second drug chambers is provided in a straight strip shape with a certain width so as to cross the container body, and the partition weak seal section The central portion in the length direction is a first weak seal portion, and both end portions in the length direction are second weak seal portions that are more difficult to peel off than the first weak seal portion. Further, the first weak seal portion is opposed to the communication inhibiting weak seal portion provided in the first medicine chamber. When this container is used, if the second drug chamber without the weak seal portion for inhibiting communication is pressed from the outside to increase the fluid pressure in the drug chamber and the weak seal portion for separation is peeled off, The first weak seal portion at the center of the weak seal portion is peeled off, and the medicine that has flowed into the first medicine chamber from the peeled partition weak seal portion central portion is in communication with the first weak seal portion. The weak seal part for communication is peeled off by colliding with the weak seal part for inhibition and increasing the internal pressure of the first drug chamber. As a result, a medicine in which two medicines are mixed can be instilled from the discharge port.
As described above, the communication operation between the first drug chamber and the second drug chamber and the peeling operation of the weak seal portion for blocking communication can be performed by a single operation of pressing one drug chamber.

JP 2006-43061 A

However, the medical multi-chamber container of Patent Document 1 has the following problems.
That is, since the container described in Patent Document 1 is already mixed after the first weak seal portion and the weak seal portion for communication inhibition have been peeled off, the second weak seal portion is peeled off. Even if not, it is ready to be administered to patients. Further, in a state where the first weak seal portion is peeled off, it is difficult to apply an internal pressure enough to peel off the second weak seal portion. For this reason, the second weak seal portion may be used in the state of the unpeeled seal portion.
And when such a non-peeled strip-shaped seal part protrudes into the drug chamber and the medical container in the state where it falls, it is easy to break the bag from the vicinity of the end of the non-peeled strip-shaped seal part in the container. There was a problem.

As shown in FIG. 6, the medical multi-chamber container 100 is packed in an outer packaging bag 103 made of a film having a barrier property by being folded using the partition weak seal portion 102 as a fold line. The reason for folding and packing is to avoid the weak seal portion 102 for partitioning from being peeled off due to an unexpected force during transportation. The two films 101 constituting the medical multi-chamber container 100 are sealed at the end of the bent portion of the seal portion of the container side indicated by the arrow Q of the medical multi-chamber container 100 folded in the outer packaging bag. It is thicker and thicker than a single film, and since the container is folded, it cannot move freely and is hard to deform.
For this reason, the end Q of the bent portion of the seal portion on the container side and the inner surface of the outer packaging bag 103 are rubbed during transportation, a pinhole is generated in the outer packaging bag 103, and the barrier property of the outer packaging bag is lost. There was a problem that the quality of the medicine deteriorated.

  The present invention has been made in view of the above-described problems, and can prevent the drug before mixing from being administered, and can be easily mixed by a single operation of pressing one drug chamber. An object of the present invention is to provide a medical multi-chamber container that is excellent in impact resistance that cannot be easily broken even if dropped and that does not cause a pinhole in the outer packaging. To do.

  In order to achieve the above object, the medical multi-chamber container according to the present invention is formed by sealing the peripheral edges of overlapping films, and for partitioning a plurality of drug chambers and the plurality of drug chambers so as to communicate with each other. A weak seal portion, a drug discharge port provided in one of the drug chambers, and temporarily blocks the flow of the drug from the drug chamber to the port, and is opposed to the partition weak seal portion. And a pair of concave shapes that are provided continuously from the opposing peripheral seal portions and are recessed toward the inside of the medical multi-chamber container. The partition weak seal portion is provided so as to connect the bottom portions of the concave seal portion, and a notch portion not having the film is formed in an inner portion of the concave seal portion. Special that It is set to.

  Further, in the medical multi-chamber container according to the present invention, formed by sealing the peripheral edges of the overlapping films, a plurality of drug chambers, and a weak seal section for partitioning the plurality of drug chambers so as to communicate with each other, A medicine discharge port provided in one of the medicine chambers, and an inflow prevention weak seal that temporarily blocks the inflow of medicine from the medicine chamber to the port and is opposed to the partition weak seal portion. A medical multi-chamber container having a pair of concave seal portions that are provided continuously from the opposing peripheral seal portions and that are recessed toward the inside of the medical multi-chamber container. The partition weak seal portion is provided so as to connect the bottom portions of the concave seal portion, and the inner portion of the concave seal portion is an unsealed portion formed by the overlapping films.

According to the medical multi-chamber container according to the present invention, when the mixed medicine is poured out from the port of the container and administered to the patient, the one medicine room not having the weak seal portion for inflow prevention is externally provided. By pressing and increasing the internal pressure of the medicine chamber, the partition weak seal part is peeled off. Then, the medicine that has flowed into the other medicine chamber having the inflow prevention weak seal portion from the separated compartment weak seal portion collides with the inflow prevention weak seal portion facing the compartment weak seal portion, and the other medicine The internal pressure of the chamber also rises and the weak seal part for inflow prevention peels. Thereby, the medicines in the two medicine chambers are mixed with each other, and the mixed medicine can be instilled from the port. Therefore, in the medical multi-chamber container according to the present invention, the operation of communicating the plurality of drug chambers and the operation of pressing the other drug chamber having the inflow prevention weak seal portion are performed by moving the one drug chamber from the outside. It can be performed by a series of operations of pressing.
At this time, since the inflow prevention weak seal portion for temporarily preventing the inflow of the medicine to the port is provided, before the medicines in the plurality of medicine chambers partitioned by the compartment weak seal portion are mixed, It is possible to prevent the drug from being administered.

  In addition, since the partition weak seal portion is provided with a pair of concave seal portions, the length dimension is shortened. When the container with the partition weak seal portion peeled off, as in the case where there is a hard unpeeled portion, it is possible to prevent the film from being broken by the vicinity of the end of the unpeeled portion. There is an advantage that it is difficult to bag and has excellent impact resistance.

  Further, in the medical multi-chamber container according to the present invention, when the weak seal portion for partitioning is folded in half as a folding line and packed in an outer package, a notch portion is formed in the inner portion of the concave seal portion. In this case, the side seal portion does not have a bent portion, and the film does not exist at a position corresponding to the end of the side seal portion. Even when the inner part of the concave seal part is an unsealed part, there is no bent part of the side seal part, and two sheets that are not sealed at the position corresponding to the end of the bent part of the side seal part There is a film. Therefore, in either case, the end of the bent portion of the side seal portion is less rigid than the state where the films are sealed and does not have a hard end portion. Therefore, the end of the bent portion of the side seal portion and the inner surface of the outer packaging bag can be rubbed during transportation, etc., thereby preventing the occurrence of pinholes in the outer packaging bag. Sex is maintained and the quality of the drug can be maintained.

In particular, when the notch part of the inner part of the concave seal part is formed at the position corresponding to the end of the bent part of the side seal part in a state where the weak seal part for the compartment is folded in half with the folding line Since no film is present in the cutout portion, the end of the bent portion of the side seal portion is further less rigid than the unsealed portion described above, and has a configuration without a hard end portion.
Moreover, when there are two films that are not sealed on the inner part of the concave seal part (in the case of the above-mentioned unsealed part), water remains between the two films during the high-pressure steam sterilization treatment. However, if there is no film in the cutout part of the inner part of the concave seal part, water will not remain in the inner part of the concave seal part, there will be no defects such as generation of bacteria, Improvements can be made.

  In the medical multi-chamber container according to the present invention, it is preferable that the partition weak seal portion has a peel strength greater at the center portion in the longitudinal direction than at both end portions near the concave seal portion.

In this case, when the compartment weak seal part is folded in half as a fold line, a load is applied to the plurality of drug chambers, and a great force acts on the longitudinal center part of the compartment weak seal part. However, by setting the peel strength at the center portion to be larger than that at both end portions, it is possible to suppress the separation of the partition weak seal portion. Moreover, peeling of the weak seal part for division can be suppressed also when the unexpected pressing force at the time of transportation is applied.
Furthermore, it can be minimized or eliminated that an unpeeled portion remains at the end in the longitudinal direction of the weak seal portion for partitioning after communication. Even if an unpeeled portion remains at the longitudinal end, the peel strength is lower than the peel strength at the central portion in the longitudinal direction. This can be prevented as much as possible, thereby preventing the container from being broken.

According to the medical multi-chamber container of the present invention, it is possible to prevent the drug before mixing from being administered.
Moreover, it can be easily mixed by a single operation of pressing one of the drug chambers, has excellent impact resistance that does not easily break the bag when dropped, and has a pinhole in the outer packaging bag. There is an effect that can prevent the occurrence of.

It is a top view which shows the medical multi-chamber container by the 1st Embodiment of this invention. It is a perspective view of the folded state of the medical multi-chamber container shown in FIG. It is a side view of the medical multi-chamber container shown in FIG. It is a top view which shows the medical multi-chamber container by 2nd Embodiment, Comprising: It is a figure corresponding to FIG. It is a perspective view of the folded state of the medical multiple-chamber container shown in FIG. It is a perspective view which shows the state which folded the conventional medical multi-chamber container and was wrapped with the outer packaging bag.

  Hereinafter, the medical multi-chamber container by embodiment of this invention is demonstrated based on drawing.

(First embodiment)
FIG. 1 shows an example of a medical multi-chamber container (hereinafter, simply referred to as “container 1”) according to the present embodiment in a state in which contents (not shown) made of a medicine are filled.
The container 1 is formed by sealing the peripheral edges of the overlapping films 11, and partitions the plurality (here, two) of drug chambers 12 (12A, 12B) and the plurality of drug chambers 12A, 12B so as to communicate with each other. The weak seal portion 13 for use, the medicine discharge port 14 provided in one medicine chamber 12 (here, the second medicine chamber 12B), and the inflow of medicine from the second medicine chamber 12B to the port 14 are temporarily And an inflow blocking weak seal portion 15 for blocking.

  Here, in the following description, the axis of the port 14 is referred to as a container axis O. In the container 1, the port 14 side along the container axis O is referred to as a lower side, and the opposite side is referred to as an upper side. A direction along the container axis O is referred to as a vertical direction Y, and a horizontal direction orthogonal to the vertical direction Y is referred to as a width direction X. The plurality of drug chambers 12A and 12B are arranged in the vertical direction Y.

  The container 1 is formed in a substantially rectangular shape in plan view, and a pair of sheet-like films 11 on the front and rear surfaces are overlapped with their peripheral edges aligned with each other, and the entire periphery is sealed by a peripheral seal portion. ing. Side seal portions 11A, 11A extending in the vertical direction Y are provided at both ends in the width direction X of the container 1 as the peripheral seal portions, and the side seal portions 11A in the width direction X are provided on the lower side and the upper side. An upper seal portion 11B and a lower seal portion 11C that are wider than 11A and extend in the width direction X are provided.

  The upper seal part 11B is provided with a suspension hole 11a at the center in the width direction X. The suspension hole 11a is a hole used when the container 1 is suspended and used. On the left and right sides of the suspension hole 11a of the upper seal portion 11B, there are formed portions (first unbonded portions 11b) where the overlapping films 11 and 11 are not bonded to each other. The periphery of the first unbonded portion 11b is bonded over the entire periphery.

  In the lower seal portion 11C, the port 14 is located at the center in the width direction X, and on the left and right sides of the port 14, there are portions where the overlapping films 11, 11 are not bonded (second unbonded portion 11c). Is formed. The periphery of the second unbonded portion 11c is bonded over the entire periphery.

  Furthermore, the container 1 is connected to the side seal portions 11A and 11A facing the width direction X, and the shape of the seal is changed in the center portion in the vertical direction Y of the side seal portion 11A in the width direction X of the container 1. It has a pair of left and right concave seal portions 16 (16A, 16B) recessed in a curved shape toward the inside. The partition weak seal portion 13 is provided so as to connect the bottom portions 16a and 16a of the concave seal portions 16A and 16B. The film 11 is cut along the inner periphery 16b of each of the pair of left and right concave seal portions 16A and 16B. That is, the notch part K is formed in the inner part of the concave seal parts 16A and 16B without the overlapping film 11.

  In the concave seal portion 16, the concave height H representing the degree of concave toward the inner side of the container 1 in the width direction X is a total of 2H of the concave heights of the pair of concave seal portions 16 </ b> A and 16 </ b> B. 10 to 50% of the total width W (length dimension in the width direction X) of the container 1 in which the total length 2H of the length in the width direction X and the recess height of the pair of concave seal portions 16A and 16B is combined, preferably 15 to 45 % Is preferable. If the total 2H of the dent heights is 10% or more, an unopened portion is unlikely to remain at the longitudinal end portion of the partitioning weak seal portion 13, and even when the container 1 falls, the unopened portion is located near the end of the unopened portion. Bag breakage is less likely to occur. Moreover, if the total 2H of the dent heights is 50% or less, the amount of the contents stored in the medicine chamber 12 can be sufficiently maintained.

The concave seal portion 16 preferably has a curvature radius of 15 mm to 30 mm at the protruding tip (dented bottom portion 16a). If this radius of curvature is 15 mm or more, bag breakage is unlikely to occur even when dropped. Moreover, if this curvature radius is 30 mm or less, the accommodation capacity of the contents of the medicine chamber 12 can be kept sufficiently.
Further, although the concave seal portions 16A and 16B shown in FIG. 1 are symmetric in the width direction X in the present embodiment, they are not limited to this and may be asymmetric.

  The partition weak seal portion 13 is formed in a straight strip shape along the width direction X so as to connect the bottom portions 16a and 16a of the pair of left and right concave seal portions 16A and 16B. The partition weak seal portion 13 is provided at a position facing the inflow blocking weak seal portion 15 provided in the second drug chamber 12B. Although the width dimension D1 of the weak seal part 13 for division is not specifically limited, For example, it determines to about 5 mm-20 mm.

  The partition weak seal portion 13 is sealed so that two overlapping films 11 and 11 can be peeled from each other, and separates the two drug chambers 12A and 12B so as to communicate with each other. The partition weak seal 13 isolates the drug chambers 12A and 12B in a state before use and blocks communication between the two, and presses the adjacent drug chambers 12A and 12B from the outside when in use. It can be made to peel by raising the internal pressure of chamber 12A, 12B. The drug chambers 12A and 12B communicate with each other by the separation of the partition weak seal portion 13.

  Here, it is preferable that the partition weak seal portion 13 has a T-shaped peel strength measured at a tensile speed of 300 mm / min in accordance with JIS K6854-3 at a width of 1.5 to 10 N / 15 mm, and further 2.5. It is more preferable that the width is ˜7 N / 15 mm. By setting it as such a range, there exists an advantage which can peel the weak seal part 13 for division without destroying the container 1 without using excessive force at the time of use.

Moreover, although the peeling strength of the weak seal part 13 for division may be constant in the width direction X of the container 1, changing in the width direction X of the container 1 is also a preferable aspect. For example, it is also preferable to increase the peel strength at the center portion (reference numeral 13a in FIG. 1) in the width direction X and lower the peel strength at both end portions 13b and 13c in the width direction X than the center portion 13a. Specifically, it is preferable that the peel strength at both end portions 13b and 13c is 20 to 80% of the peel strength at the central portion 13a.
By doing in this way, it can minimize or eliminate that the unpeeled part of both ends 13b and 13c remains after communication. If the unpeeled portion remains, the remaining end of the partition weak seal portion 13 becomes a stress concentration portion when the container 1 is dropped, and the container 1 is easily broken. If the peel strength at both end portions 13b and 13c in the width direction X is lowered, the unpeeled portion hardly remains, and even if it remains, the peel strength is lower than the peel strength at the center portion 13a in the width direction X. Since it becomes a weak seal part which peels more easily among the possible weak seal parts 13 for division, it can prevent as much as possible that it becomes a stress concentration part which leads to a broken bag. This can prevent the container 1 from being broken.

  Moreover, in the weak seal part 13 for division, in order to make the peeling strength of the center part 13a of the width direction X large, and to make the peeling strength of the both ends 13b and 13c of the width direction X small, at the time of manufacture of the weak seal part 13 for divisions The sealing pressure at the central portion 13a is increased by the method of setting the heat sealing temperature at the central portion 13a to be high and the both end portions 13b and 13c to be low, and the shape of the seal mold at the time of manufacturing the sealing portion, and the both end portions 13b and 13c. And a method of increasing the amount of heat received by the central portion 13a and reducing the amount of heat received by both end portions 13b and 13c.

The port 14 provided in the lower seal portion 11C is a member that is sandwiched and fixed between the two films 11, and is used for injecting and discharging the medicine, enabling access from outside the container to the inside of the container. It is a passage to do.
The port 14 is made of an injection-molded product of synthetic resin, and has an opening sealed with an elastic body such as rubber (not shown) that can be pierced so that a needle can be inserted. A tube may be used instead of the port 14.

On the second drug chamber 12B side of the port 14, the inflow blocking weak seal portion 15 for temporarily blocking the drug inflow from the second drug chamber 12B to the port 14 is provided.
The inflow blocking weak seal portion 15 extends continuously from the lower seal portion 11C, and is provided in a semicircular shape so as to surround the opening of the port 14 on the second drug chamber 12B side. In addition, about the shape of the weak seal part 15 for inflow prevention, it is not limited to a semicircle shape, It can be set as arbitrary shapes, such as an ellipse and a polygonal partial shape.

The inflow blocking weak seal portion 15 preferably has a T-shaped peel strength measured at a pulling speed of 300 mm / min in accordance with JIS K6854-3 at a width of 3 to 20 N / 15 mm, and more preferably 4 to 12 N / 15 mm width. More preferably. Further, it is preferable that the peel strength of the inflow blocking weak seal portion 15 is higher than the peel strength of the partition weak seal portion 13.
In this way, when the second drug chamber 12B provided with the port 14 is pressed from the outside, the partition weak seal portion 13 does not peel off after the inflow prevention weak seal portion 15, and the inflow prevention is achieved. Only the weak seal portion 15 is peeled off and the unmixed medicine does not flow out from the port 14. In this way, the inflow blocking weak seal portion 15 has a function of temporarily blocking the unmixed medicine from flowing into the port 14.

  The space between the inflow blocking weak seal portion 15 and the port 14 preferably contains a small amount of 1 mL or less of physiological saline or distilled water that can sterilize the space when heated to a high temperature. . In addition, a slit-like unsealed portion that allows a sterilizable amount of liquid to flow from the drug chamber 12 may be provided in the inflow blocking weak seal portion 15.

As the materials of the film 11 and the port 14 constituting the container 1 of the present embodiment, those made of a thermoplastic resin are employed.
The thermoplastic resin is not particularly limited as long as it is used in the medical field. Vinyl chloride, ethylene vinyl acetate copolymer, polyolefin, polyamide, polyester, polyethersulfone, cyclic polyolefin, cyclic polyolefin can be used. Examples thereof include a copolymer, an ethylene elastomer, a styrene elastomer, and a mixture of these resins.
In addition, these thermoplastic resins are partially cross-linked for the purpose of improving heat resistance, or mixed with low melting point components such as ultra-low density polyethylene, ethylene elastomer, and styrene elastomer in order to actively block. May be.

  Of these thermoplastic resins, polyolefin is preferable because it is inexpensive and excellent in transparency and flexibility. Examples of the polyolefin include polyethylene resins such as high-density polyethylene, low-density polyethylene, and linear low-density polyethylene, olefin-based elastomers such as ethylene-butadiene random copolymer, polypropylene, ethylene, or propylene composed of α-olefin and propylene. Examples thereof include a polypropylene block copolymer resin containing a random copolymer and an ethylene propylene copolymer elastomer.

  The film 11 constituting the container 1 may be a single layer film made of one kind of film or a multilayer film in which a plurality of kinds of films are laminated. In the case of a single layer film, since it is excellent in transparency and flexibility, linear low density polyethylene, ethylene propylene random copolymer, ethylene propylene block copolymer, a mixture of polypropylene resin and styrene elastomer, etc. A film is preferred.

  These films are manufactured by a manufacturing method such as T-die molding, water cooling or air cooling inflation molding, or laminate molding. A film produced by water-cooled inflation molding is preferred from the viewpoint of transparency and hygiene. And the thickness of a film is 5-1000 micrometers, Preferably about 50-500 micrometers is used.

Here, the manufacturing method of the container 1 mentioned above is demonstrated. First, the container 1 is created by sealing the stacked film 11 into a target shape. As a sealing method, a heat sealing method or an impulse sealing method in which pressure is applied to the heating plate to hold down the film 11 can be employed. A thermal mold can be used for sealing the port 14 and the film 11. In addition, when the dimension of the container 1 is about 100 mL to 5 L, the seal width D2 of the concave seal portion 16 and the side seal portion 11A is in the range of 3 mm to 15 mm, preferably 4 mm to 10 mm.
Examples of the combination of drugs include a combination of an amino acid infusion solution and a glucose infusion solution, an antibiotic and a solution thereof.

  Next, the operation of the medical multi-chamber container (container 1) of the present embodiment configured as described above will be described based on the drawings.

When the medicine mixed from the port 14 is poured out and administered to a patient using the container 1 of the present embodiment shown in FIG. 1, the upper first medicine chamber 12A having no weak seal portion 15 for preventing inflow is provided. Is pressed from the outside to increase the internal pressure of the first drug chamber 12A, the partition weak seal portion 13 is peeled off, and the lower weak seal portion 15 having the inflow prevention weak seal portion 15 is separated from the separated partition weak seal portion 13. The medicine that has flowed into the two medicine chambers 12B collides with the inflow prevention weak seal section 15 facing the partition weak seal section 13, and the internal pressure of the second medicine chamber 12B also rises, causing the inflow prevention weak seal section 15 to peel off. To do. Thereby, the medicines in the two medicine chambers 12 </ b> A and 12 </ b> B are mixed, and the mixed medicine can be instilled from the port 14. Therefore, the operation of communicating the upper and lower drug chambers 12A and 12B and the operation of separating the inflow blocking weak seal portion 15 can be performed by a series of operations of pressing the first drug chamber 12A from the outside.
At this time, since the inflow prevention weak seal portion 15 for temporarily preventing the inflow of the medicine into the port 14 is provided, the medicine in the upper and lower medicine chambers 12A and 12B partitioned by the partition weak seal portion 13 is provided. It is possible to prevent the drug from being administered before the is mixed.

  Further, the partition weak seal portion 13 is easily peeled over the entire width direction X because the length dimension in the longitudinal direction (width direction X) is shortened by providing the pair of concave seal portions 16A and 16B. Since the unpeeled portion is unlikely to remain, it is possible to prevent the film from being broken by the end of the unpeeled portion when the container 1 in a state where the weak seal portion 13 for separation has fallen, There is an advantage that it is difficult to break the bag and has excellent impact resistance.

  Further, as shown in FIGS. 2 and 3, when the container 1 is folded in half with the partition weak seal portion 13 as a folding line and packed in the outer packaging bag 2, the side seal portion 11A is bent. There is no portion, the notch K of the inner portion of the concave seal portions 16A, 16B is located at a position P corresponding to the end of the bent portion of the side seal portion 11A, and the film 11 does not exist in the notch K Because of the configuration, the position P corresponding to the end of the bent portion of the side seal portion 11A is less rigid than the state in which the films 11 are sealed and bent, and does not have a hard end portion. become. Therefore, the position P corresponding to the end of the bent portion of the side seal portion 11A and the inner surface of the outer packaging bag 2 are rubbed during transportation or the like to prevent a problem that a pinhole is generated in the outer packaging bag 2. The barrier property of the outer packaging bag is maintained, and the quality of the medicine can be maintained. Even if the boundary portion between the side seal portions 11A and 11A and the concave seal portions 16A and 16B is rubbed with the outer packaging bag 2, it is not a folded portion, so that it is more rigid than a state in which the films 11 are sealed and bent. Therefore, it is possible to prevent the occurrence of pinholes in the outer packaging bag 2.

  In addition, since there is no film 11 in the cutout portion K of the inner portion of the concave seal portion 16, water does not remain in the inner portion of the concave seal portion 16 during the high-pressure steam sterilization process, and there is no problem such as generation of bacteria. Improvement in hygiene can be achieved.

  Moreover, in this Embodiment, when the division weak seal part 13 is folded in two as a fold line, a load is applied to the upper and lower drug chambers 12A and 12B, and the longitudinal direction (width direction) of the division weak seal part 13 is applied. X) Even if a large force acts on the central portion 13a, the peeling strength of the central portion 13a is set larger than both end portions 13b and 13c, thereby suppressing the peeling of the weak seal portion 13 for partitioning. be able to. In addition, even when an unexpected pressing force is applied during transportation, peeling of the partition weak seal portion 13 can be suppressed.

As described above, in the medical multi-chamber container according to the present embodiment, it is possible to prevent the medicine before mixing from being administered.
In addition, this is a medical multi-chamber container in which the drug mixing and the inflow prevention weak seal portion 15 can be easily separated by a single operation of pressing one of the drug chambers 12A (or 12B). It is excellent and produces an effect that no pinhole is generated in the outer packaging bag 2.

  Next, another embodiment of the medical multi-chamber container of the present invention will be described with reference to the accompanying drawings. The same reference numerals are used for the same or similar members and parts as those in the first embodiment. A description will be omitted, and a configuration different from that of the first embodiment will be described.

(Second Embodiment)
As shown in FIG. 4, the medical multi-chamber container (container 1 </ b> A) according to the second embodiment is not formed with the notch K (see FIG. 1) along the inner periphery 16 b of the concave seal portion 16. The inner portion of the concave seal portion 16 (portion 11d) is an unsealed portion S where the overlapping films 11d and 11d are not sealed, and a gap is formed between them.

  Also in this case, as shown in FIG. 5, when the compartment weak seal portion 13 is folded in half as a folding line and packed in the outer packaging bag 2, the side seal portion has no bent portion, Since the unsealed portion S of the inner portion of the concave seal portion 16 is located at the position P corresponding to the end of the bent portion of the side seal portion, it corresponds to the end of the bent portion of the side seal portion. The position P is less rigid than the state in which the films 11 are sealed, and does not have a hard end. Therefore, the position P corresponding to the end of the bent portion of the side seal portion and the inner surface of the outer packaging bag 2 can be prevented from being rubbed during transportation or the like, and pinholes can be prevented from being generated in the outer packaging bag 2. The barrier property of the outer packaging bag can be maintained, and the quality of the medicine can be maintained.

  Next, examples for supporting the effects of the medical multi-chamber container according to the above-described embodiment will be described below.

(Example)
In this example, the medical multi-chamber container (container 1A shown in FIG. 4) of the second embodiment described above is used, a film having the following structure is produced by the water-cooled inflation method, and the partition weak seal is formed. In addition to confirming the peeled state of the part, a container drop test was performed to confirm the function of the container.

The film is a multilayer film in which the outer layer / intermediate layer / inner layer is composed of high density polyethylene (HDPE) / linear low density polyethylene (LLDPE) / high density polyethylene (HDPE), respectively, and these outer layer / intermediate layer / inner layer. Each having a thickness (μm) of 25/200/25 and an outer layer / intermediate layer / inner layer density (g / cm ³ ) of 0.956 / 0.910 / 0.956, respectively. The melting point (° C.) of the inner layer is 132/110/132.
Then, the obtained film is heat-sealed under the conditions of a heating temperature of 120 to 180 ° C., a pressurizing pressure of 0.2 to 0.5 MPa, and a processing time of 1 to 5 seconds, and a medical multi-chamber container shown in FIG. Was made. The size of the medical multi-chamber container is 30 cm × 18 cm in length and width, and ports and suspension holes (suspension holes) are provided at both ends in the vertical direction.

The partition weak seal portion is provided in a straight strip shape across the both sides with a width of 1 cm at a position of 18 cm in the longitudinal direction from the port side. Furthermore, a pair of concave seal portions are provided at both ends in the longitudinal direction of the partition weak seal portion, in which a part of the left and right side seal portions is recessed.
The concave seal portion has a height (the recess height H shown in FIG. 4) of 3.5 cm, and the total recess height of the pair of concave seal portions 16A and 16B is 2H in the short direction of the medical multi-chamber container. The arc radius of the tip (bottom) of the concave seal portion is 20 mm.

And it heated using the shower-type high pressure steam sterilizer for 30 minutes at the sterilization temperature of 105 degreeC.
When the upper chamber side (corresponding to the upper drug chamber 12A shown in FIG. 4) is pressed against the container thus prepared, the weak seal portion for partitioning each chamber is opened without leaving an unpeeled portion. Subsequently, the weak seal portion for inflow prevention was opened.
Moreover, when the container was dropped from a height of 1.7 m at the hanging hole portion, it was confirmed that the container of this example did not break the bag.

  As mentioned above, although embodiment of the medical multi-chamber container by this invention was described, this invention is not limited to said embodiment, In the range which does not deviate from the meaning, it can change suitably.

For example, in the above-described embodiment, the container 1 is provided with the upper and lower two drug chambers 12A and 12B. However, three or more drug chambers may be provided by being partitioned by the partition weak seal portion 13. .
Further, in the container 1 of the first embodiment, the cutout portion K is cut along the inner periphery 16b of each of the pair of left and right concave seal portions 16A and 16B, but the cutout portion K is a concave seal portion. As long as one or more are provided in the region of the inner portion, the inner portion may not be along the inner periphery of the concave seal portion. The cutout K may have a punched shape.

  Furthermore, the shape of the container, for example, the shape of the upper seal portion 11B and the lower seal portion 11C, the size and shape of the port 14, and the like can be appropriately set without being limited to the present embodiment.

  In addition, it is possible to appropriately replace the components in the above-described embodiments with known components without departing from the spirit of the present invention.

1 container (medical multi-chamber container)
11 Film 11A Side seal part (Seal part at side edge)
12 drug chamber 12A first drug chamber 12B second drug chamber 13 partition weak seal portion 13a central portion 13b, 13c end portion 14 port 15 inflow prevention weak seal portion 16 concave seal portion 16a bottom portion H recess height K notch S Unsealed part X Width direction Y Vertical direction

Claims (3)

Formed by sealing the edges of overlapping films,
Multiple drug rooms,
A weak seal section for partitioning the plurality of medicine chambers so as to communicate with each other;
A medicine discharge port provided in one of the medicine chambers;
A weak seal part for inflow prevention temporarily blocking the inflow of medicine from the drug chamber to the port, and facing the weak seal part for partitioning;
A medical multi-chamber container comprising:
It has a pair of concave seal portions that are continuously provided from the opposing peripheral seal portions and are recessed toward the inside of the medical multi-chamber container,
The partition weak seal portion is provided so as to connect the bottom portions of the concave seal portion,
A medical multi-chamber container, wherein a cutout portion having no film is formed in an area of an inner portion of the concave seal portion. Formed by sealing the edges of overlapping films,
Multiple drug rooms,
A weak seal section for partitioning the plurality of medicine chambers so as to communicate with each other;
A medicine discharge port provided in one of the medicine chambers;
A weak seal part for inflow prevention temporarily blocking the inflow of medicine from the drug chamber to the port, and facing the weak seal part for partitioning;
A medical multi-chamber container comprising:
It has a pair of concave seal portions that are continuously provided from the opposing peripheral seal portions and are recessed toward the inside of the medical multi-chamber container,
The partition weak seal portion is provided so as to connect the bottom portions of the concave seal portion,
The medical multi-chamber container, wherein an inner portion of the concave seal portion is an unsealed portion formed by the overlapping films.   3. The medical multi-chamber container according to claim 1, wherein the weak seal portion for partitioning has a peel strength higher at a center portion in a longitudinal direction than both end portions near the concave seal portion.

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