JP2015043779A5 - - Google Patents

Info

Publication number

JP2015043779A5

JP2015043779A5 JP2014222204A JP2014222204A JP2015043779A5 JP 2015043779 A5 JP2015043779 A5 JP 2015043779A5 JP 2014222204 A JP2014222204 A JP 2014222204A JP 2014222204 A JP2014222204 A JP 2014222204A JP 2015043779 A5 JP2015043779 A5 JP 2015043779A5

Authority

JP

Japan

Prior art keywords

cell

endothelial cells

vcam

selectin

reducing

Prior art date

2014-10-31

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
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• 210000004027 cell Anatomy 0.000 claims 6
• 210000002889 endothelial cell Anatomy 0.000 claims 5
• 102000004127 Cytokines Human genes 0.000 claims 3
• 108090000695 Cytokines Proteins 0.000 claims 3
• 108010067225 Cell Adhesion Molecules Proteins 0.000 claims 2
• 102000016289 Cell Adhesion Molecules Human genes 0.000 claims 2
• 108010024212 E-Selectin Proteins 0.000 claims 2
• 102100023471 E-selectin Human genes 0.000 claims 2
• 108010035766 P-Selectin Proteins 0.000 claims 2
• 102100023472 P-selectin Human genes 0.000 claims 2
• 108010000134 Vascular Cell Adhesion Molecule-1 Proteins 0.000 claims 2
• 102100023543 Vascular cell adhesion protein 1 Human genes 0.000 claims 2
• 230000004913 activation Effects 0.000 claims 2
• 230000001404 mediated effect Effects 0.000 claims 2
• MZOFCQQQCNRIBI-VMXHOPILSA-N (3s)-4-[[(2s)-1-[[(2s)-1-[[(1s)-1-carboxy-2-hydroxyethyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-[[2-[[(2s)-2,6-diaminohexanoyl]amino]acetyl]amino]-4-oxobutanoic acid Chemical compound OC[C@@H](C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)CCCCN MZOFCQQQCNRIBI-VMXHOPILSA-N 0.000 claims 1
• 206010015866 Extravasation Diseases 0.000 claims 1
• 108010002352 Interleukin-1 Proteins 0.000 claims 1
• 101710150336 Protein Rex Proteins 0.000 claims 1
• 108010017842 Telomerase Proteins 0.000 claims 1
• 108060008682 Tumor Necrosis Factor Proteins 0.000 claims 1
• 102000000852 Tumor Necrosis Factor-alpha Human genes 0.000 claims 1
• 210000001185 bone marrow Anatomy 0.000 claims 1
• 210000003981 ectoderm Anatomy 0.000 claims 1
• 210000001900 endoderm Anatomy 0.000 claims 1
• 210000003989 endothelium vascular Anatomy 0.000 claims 1
• 230000036251 extravasation Effects 0.000 claims 1
• 210000005260 human cell Anatomy 0.000 claims 1
• 210000000265 leukocyte Anatomy 0.000 claims 1
• 230000023404 leukocyte cell-cell adhesion Effects 0.000 claims 1
• 210000003716 mesoderm Anatomy 0.000 claims 1
• 210000000130 stem cell Anatomy 0.000 claims 1