JP2014532694A5 - - Google Patents
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- Publication number
- JP2014532694A5 JP2014532694A5 JP2014539469A JP2014539469A JP2014532694A5 JP 2014532694 A5 JP2014532694 A5 JP 2014532694A5 JP 2014539469 A JP2014539469 A JP 2014539469A JP 2014539469 A JP2014539469 A JP 2014539469A JP 2014532694 A5 JP2014532694 A5 JP 2014532694A5
- Authority
- JP
- Japan
- Prior art keywords
- vitiligo
- ngf
- formulation
- hypomelanosis
- topical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 206010047642 Vitiligo Diseases 0.000 claims 20
- 108010025020 Nerve Growth Factor Proteins 0.000 claims 17
- 102000015336 Nerve Growth Factor Human genes 0.000 claims 17
- 229940053128 nerve growth factor Drugs 0.000 claims 17
- 238000009472 formulation Methods 0.000 claims 10
- 239000000203 mixture Substances 0.000 claims 10
- 208000003367 Hypopigmentation Diseases 0.000 claims 8
- 206010040868 Skin hypopigmentation Diseases 0.000 claims 8
- 238000000034 method Methods 0.000 claims 8
- 238000002360 preparation method Methods 0.000 claims 7
- 230000000699 topical effect Effects 0.000 claims 7
- 208000012641 Pigmentation disease Diseases 0.000 claims 5
- 210000003491 skin Anatomy 0.000 claims 5
- 206010027145 Melanocytic naevus Diseases 0.000 claims 4
- 208000003351 Melanosis Diseases 0.000 claims 4
- 208000007256 Nevus Diseases 0.000 claims 4
- 239000004480 active ingredient Substances 0.000 claims 4
- 230000001815 facial effect Effects 0.000 claims 4
- 208000015181 infectious disease Diseases 0.000 claims 4
- 239000000126 substance Substances 0.000 claims 4
- 230000000694 effects Effects 0.000 claims 3
- 230000002708 enhancing effect Effects 0.000 claims 3
- 230000001939 inductive effect Effects 0.000 claims 3
- 230000002265 prevention Effects 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 208000017701 Endocrine disease Diseases 0.000 claims 2
- 208000024780 Urticaria Diseases 0.000 claims 2
- 239000000556 agonist Substances 0.000 claims 2
- 230000002146 bilateral effect Effects 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 210000000232 gallbladder Anatomy 0.000 claims 2
- 230000002458 infectious effect Effects 0.000 claims 2
- 230000002757 inflammatory effect Effects 0.000 claims 2
- 230000002503 metabolic effect Effects 0.000 claims 2
- 235000016709 nutrition Nutrition 0.000 claims 2
- 208000030212 nutrition disease Diseases 0.000 claims 2
- 230000009984 peri-natal effect Effects 0.000 claims 2
- 239000002831 pharmacologic agent Substances 0.000 claims 2
- 238000001126 phototherapy Methods 0.000 claims 2
- 230000000750 progressive effect Effects 0.000 claims 2
- 208000024891 symptom Diseases 0.000 claims 2
- 239000012049 topical pharmaceutical composition Substances 0.000 claims 2
- 229930003316 Vitamin D Natural products 0.000 claims 1
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 claims 1
- 230000001476 alcoholic effect Effects 0.000 claims 1
- 239000006071 cream Substances 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- 210000002615 epidermis Anatomy 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- 239000000865 liniment Substances 0.000 claims 1
- 239000006210 lotion Substances 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 239000002674 ointment Substances 0.000 claims 1
- 239000003504 photosensitizing agent Substances 0.000 claims 1
- 230000005855 radiation Effects 0.000 claims 1
- 208000017520 skin disease Diseases 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- 239000007921 spray Substances 0.000 claims 1
- 150000003431 steroids Chemical class 0.000 claims 1
- 238000007920 subcutaneous administration Methods 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 235000019166 vitamin D Nutrition 0.000 claims 1
- 239000011710 vitamin D Substances 0.000 claims 1
- 150000003710 vitamin D derivatives Chemical class 0.000 claims 1
- QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical class C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 claims 1
- 229940046008 vitamin d Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000574A ITRM20110574A1 (it) | 2011-11-02 | 2011-11-02 | Preparato topico per indurre la pigmentazione cutanea e per il trattamento di discromie cutanee e vitiligine. |
| ITRM2011A000574 | 2011-11-02 | ||
| PCT/IT2012/000336 WO2013065078A2 (en) | 2011-11-02 | 2012-11-02 | Topical preparation containing ngf for inducing skin pigmentation and for the treatment of cutaneous dyschromias and vitiligo |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014532694A JP2014532694A (ja) | 2014-12-08 |
| JP2014532694A5 true JP2014532694A5 (enExample) | 2015-12-03 |
| JP6130846B2 JP6130846B2 (ja) | 2017-05-17 |
Family
ID=45315964
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014539469A Active JP6130846B2 (ja) | 2011-11-02 | 2012-11-02 | 皮膚の色素沈着の誘導並びに皮膚の色素異常及び白斑の治療のためのｎｇｆを含有する局所用製剤 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9402906B2 (enExample) |
| EP (1) | EP2773318B1 (enExample) |
| JP (1) | JP6130846B2 (enExample) |
| CA (1) | CA2854271C (enExample) |
| ES (1) | ES2748866T3 (enExample) |
| IL (1) | IL232419A0 (enExample) |
| IT (1) | ITRM20110574A1 (enExample) |
| WO (1) | WO2013065078A2 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT201800009384A1 (it) | 2018-10-11 | 2020-04-11 | Cosmo Srl | Peptide for cosmetic application |
| CN111282149B (zh) * | 2019-08-08 | 2024-08-16 | 南京市江宁医院 | 一种白癜风纹饰治疗仪 |
| IT202000005542A1 (it) * | 2020-03-16 | 2021-09-16 | Themis S R L | Metodo cosmetico per il trattamento della pelle e per la ricrescita dei capelli |
| IT202000020287A1 (it) | 2020-08-20 | 2022-02-20 | Colosseum Combinatorial Chemistry Centre For Tech Societa A Responsabilita Limitata In Forma Abbrevi | Peptide per applicazioni terapeutiche in campo dermatologico |
| WO2023072877A1 (en) * | 2021-10-25 | 2023-05-04 | Ellennbe Gmbh | Pharmaceutical composition and kit comprising an immunomodulatory substance for treating diseases |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7196055B2 (en) * | 1994-08-31 | 2007-03-27 | Trustees Of Boston University | Inhibition of apoptosis in keratinocytes by a ligand of p75 nerve growth factor receptor |
| US6867179B1 (en) * | 1994-08-31 | 2005-03-15 | Trustees Of Boston University | Methods of inducing hair growth and coloration |
| US6063757A (en) * | 1995-11-29 | 2000-05-16 | Urso; Richard G. | Wound treatment method with nerve growth factor |
| US6143723A (en) * | 1996-05-20 | 2000-11-07 | Ramaiah; Abburi | Pigmentory agent |
-
2011
- 2011-11-02 IT IT000574A patent/ITRM20110574A1/it unknown
-
2012
- 2012-11-02 WO PCT/IT2012/000336 patent/WO2013065078A2/en not_active Ceased
- 2012-11-02 ES ES12813535T patent/ES2748866T3/es active Active
- 2012-11-02 EP EP12813535.7A patent/EP2773318B1/en active Active
- 2012-11-02 JP JP2014539469A patent/JP6130846B2/ja active Active
- 2012-11-02 CA CA2854271A patent/CA2854271C/en active Active
-
2014
- 2014-05-01 IL IL232419A patent/IL232419A0/en unknown
- 2014-05-02 US US14/268,861 patent/US9402906B2/en active Active
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