ITRM20110574A1 - Preparato topico per indurre la pigmentazione cutanea e per il trattamento di discromie cutanee e vitiligine. - Google Patents
Preparato topico per indurre la pigmentazione cutanea e per il trattamento di discromie cutanee e vitiligine. Download PDFInfo
- Publication number
- ITRM20110574A1 ITRM20110574A1 IT000574A ITRM20110574A ITRM20110574A1 IT RM20110574 A1 ITRM20110574 A1 IT RM20110574A1 IT 000574 A IT000574 A IT 000574A IT RM20110574 A ITRM20110574 A IT RM20110574A IT RM20110574 A1 ITRM20110574 A1 IT RM20110574A1
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- IT
- Italy
- Prior art keywords
- vitiligo
- ngf
- skin
- preparation
- hypomelanosis
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- 229960003415 propylparaben Drugs 0.000 description 1
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- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 description 1
- 206010037844 rash Diseases 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
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- 229930002330 retinoic acid Natural products 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- XWGJFPHUCFXLBL-UHFFFAOYSA-M rongalite Chemical compound [Na+].OCS([O-])=O XWGJFPHUCFXLBL-UHFFFAOYSA-M 0.000 description 1
- 235000019719 rose oil Nutrition 0.000 description 1
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- 206010040882 skin lesion Diseases 0.000 description 1
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- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 1
- 235000010234 sodium benzoate Nutrition 0.000 description 1
- 239000004299 sodium benzoate Substances 0.000 description 1
- 229960003885 sodium benzoate Drugs 0.000 description 1
- 229940001607 sodium bisulfite Drugs 0.000 description 1
- 229960004599 sodium borate Drugs 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 229940001593 sodium carbonate Drugs 0.000 description 1
- 235000017550 sodium carbonate Nutrition 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 229960001790 sodium citrate Drugs 0.000 description 1
- 235000011083 sodium citrates Nutrition 0.000 description 1
- 229940023144 sodium glycolate Drugs 0.000 description 1
- 235000010267 sodium hydrogen sulphite Nutrition 0.000 description 1
- 235000011121 sodium hydroxide Nutrition 0.000 description 1
- 239000001540 sodium lactate Substances 0.000 description 1
- 235000011088 sodium lactate Nutrition 0.000 description 1
- 229940005581 sodium lactate Drugs 0.000 description 1
- 229940001584 sodium metabisulfite Drugs 0.000 description 1
- 235000010262 sodium metabisulphite Nutrition 0.000 description 1
- 235000010339 sodium tetraborate Nutrition 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 235000010199 sorbic acid Nutrition 0.000 description 1
- 239000004334 sorbic acid Substances 0.000 description 1
- 229940075582 sorbic acid Drugs 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 230000007480 spreading Effects 0.000 description 1
- 238000003892 spreading Methods 0.000 description 1
- 229940031439 squalene Drugs 0.000 description 1
- TUHBEKDERLKLEC-UHFFFAOYSA-N squalene Natural products CC(=CCCC(=CCCC(=CCCC=C(/C)CCC=C(/C)CC=C(C)C)C)C)C TUHBEKDERLKLEC-UHFFFAOYSA-N 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 150000005846 sugar alcohols Polymers 0.000 description 1
- 230000037072 sun protection Effects 0.000 description 1
- 239000002344 surface layer Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 230000002889 sympathetic effect Effects 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 229960001367 tartaric acid Drugs 0.000 description 1
- UEUXEKPTXMALOB-UHFFFAOYSA-J tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O UEUXEKPTXMALOB-UHFFFAOYSA-J 0.000 description 1
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- 239000010936 titanium Substances 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
- 229960000984 tocofersolan Drugs 0.000 description 1
- 229930003799 tocopherol Natural products 0.000 description 1
- 239000011732 tocopherol Substances 0.000 description 1
- 235000019149 tocopherols Nutrition 0.000 description 1
- 229940100611 topical cream Drugs 0.000 description 1
- 229940025703 topical product Drugs 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 229960001727 tretinoin Drugs 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- IMNIMPAHZVJRPE-UHFFFAOYSA-N triethylenediamine Chemical compound C1CN2CCN1CC2 IMNIMPAHZVJRPE-UHFFFAOYSA-N 0.000 description 1
- JEJAMASKDTUEBZ-UHFFFAOYSA-N tris(1,1,3-tribromo-2,2-dimethylpropyl) phosphate Chemical compound BrCC(C)(C)C(Br)(Br)OP(=O)(OC(Br)(Br)C(C)(C)CBr)OC(Br)(Br)C(C)(C)CBr JEJAMASKDTUEBZ-UHFFFAOYSA-N 0.000 description 1
- BSVBQGMMJUBVOD-UHFFFAOYSA-N trisodium borate Chemical compound [Na+].[Na+].[Na+].[O-]B([O-])[O-] BSVBQGMMJUBVOD-UHFFFAOYSA-N 0.000 description 1
- 208000009999 tuberous sclerosis Diseases 0.000 description 1
- 238000009192 ultraviolet light therapy Methods 0.000 description 1
- VBEQCZHXXJYVRD-GACYYNSASA-N uroanthelone Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CS)C(=O)N[C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(C)C)[C@@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CCSC)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)CNC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CS)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CS)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(N)=O)C(C)C)[C@@H](C)CC)C1=CC=C(O)C=C1 VBEQCZHXXJYVRD-GACYYNSASA-N 0.000 description 1
- 239000012178 vegetable wax Substances 0.000 description 1
- 230000002747 voluntary effect Effects 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- 239000011787 zinc oxide Substances 0.000 description 1
- 235000004835 α-tocopherol Nutrition 0.000 description 1
- 239000002076 α-tocopherol Substances 0.000 description 1
- 150000003772 α-tocopherols Chemical class 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/04—Preparations for care of the skin for chemically tanning the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Psychology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Birds (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000574A ITRM20110574A1 (it) | 2011-11-02 | 2011-11-02 | Preparato topico per indurre la pigmentazione cutanea e per il trattamento di discromie cutanee e vitiligine. |
| ES12813535T ES2748866T3 (es) | 2011-11-02 | 2012-11-02 | Preparación tópica que contiene NGF para inducir la pigmentación de la piel y para el tratamiento de discromías cutáneas y vitiligo |
| EP12813535.7A EP2773318B1 (en) | 2011-11-02 | 2012-11-02 | Topical preparation containing ngf for inducing skin pigmentation and for the treatment of cutaneous dyschromias and vitiligo |
| PCT/IT2012/000336 WO2013065078A2 (en) | 2011-11-02 | 2012-11-02 | Topical preparation containing ngf for inducing skin pigmentation and for the treatment of cutaneous dyschromias and vitiligo |
| CA2854271A CA2854271C (en) | 2011-11-02 | 2012-11-02 | Topical preparation containing ngf for inducing skin pigmentation and for the treatment of cutaneous dyschromias and vitiligo |
| JP2014539469A JP6130846B2 (ja) | 2011-11-02 | 2012-11-02 | 皮膚の色素沈着の誘導並びに皮膚の色素異常及び白斑の治療のためのｎｇｆを含有する局所用製剤 |
| IL232419A IL232419A0 (en) | 2011-11-02 | 2014-05-01 | A topical preparation containing nerve growth factor to induce skin pigmentation and to treat poor skin coloration and brightening |
| US14/268,861 US9402906B2 (en) | 2011-11-02 | 2014-05-02 | Topical preparation containing NGF for inducing skin pigmentation and for the treatment of cutaneous dyschromias and vitiligo |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000574A ITRM20110574A1 (it) | 2011-11-02 | 2011-11-02 | Preparato topico per indurre la pigmentazione cutanea e per il trattamento di discromie cutanee e vitiligine. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ITRM20110574A1 true ITRM20110574A1 (it) | 2013-05-03 |
Family
ID=45315964
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT000574A ITRM20110574A1 (it) | 2011-11-02 | 2011-11-02 | Preparato topico per indurre la pigmentazione cutanea e per il trattamento di discromie cutanee e vitiligine. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9402906B2 (enExample) |
| EP (1) | EP2773318B1 (enExample) |
| JP (1) | JP6130846B2 (enExample) |
| CA (1) | CA2854271C (enExample) |
| ES (1) | ES2748866T3 (enExample) |
| IL (1) | IL232419A0 (enExample) |
| IT (1) | ITRM20110574A1 (enExample) |
| WO (1) | WO2013065078A2 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT201800009384A1 (it) | 2018-10-11 | 2020-04-11 | Cosmo Srl | Peptide for cosmetic application |
| CN111282149B (zh) * | 2019-08-08 | 2024-08-16 | 南京市江宁医院 | 一种白癜风纹饰治疗仪 |
| IT202000005542A1 (it) * | 2020-03-16 | 2021-09-16 | Themis S R L | Metodo cosmetico per il trattamento della pelle e per la ricrescita dei capelli |
| IT202000020287A1 (it) | 2020-08-20 | 2022-02-20 | Colosseum Combinatorial Chemistry Centre For Tech Societa A Responsabilita Limitata In Forma Abbrevi | Peptide per applicazioni terapeutiche in campo dermatologico |
| WO2023072877A1 (en) * | 2021-10-25 | 2023-05-04 | Ellennbe Gmbh | Pharmaceutical composition and kit comprising an immunomodulatory substance for treating diseases |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999039728A2 (en) * | 1998-02-04 | 1999-08-12 | Trustees Of Boston University | Methods of inducing hair growth and coloration |
| US6063757A (en) * | 1995-11-29 | 2000-05-16 | Urso; Richard G. | Wound treatment method with nerve growth factor |
| US6143723A (en) * | 1996-05-20 | 2000-11-07 | Ramaiah; Abburi | Pigmentory agent |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6867179B1 (en) * | 1994-08-31 | 2005-03-15 | Trustees Of Boston University | Methods of inducing hair growth and coloration |
-
2011
- 2011-11-02 IT IT000574A patent/ITRM20110574A1/it unknown
-
2012
- 2012-11-02 WO PCT/IT2012/000336 patent/WO2013065078A2/en not_active Ceased
- 2012-11-02 ES ES12813535T patent/ES2748866T3/es active Active
- 2012-11-02 EP EP12813535.7A patent/EP2773318B1/en active Active
- 2012-11-02 JP JP2014539469A patent/JP6130846B2/ja active Active
- 2012-11-02 CA CA2854271A patent/CA2854271C/en active Active
-
2014
- 2014-05-01 IL IL232419A patent/IL232419A0/en unknown
- 2014-05-02 US US14/268,861 patent/US9402906B2/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6063757A (en) * | 1995-11-29 | 2000-05-16 | Urso; Richard G. | Wound treatment method with nerve growth factor |
| US6143723A (en) * | 1996-05-20 | 2000-11-07 | Ramaiah; Abburi | Pigmentory agent |
| WO1999039728A2 (en) * | 1998-02-04 | 1999-08-12 | Trustees Of Boston University | Methods of inducing hair growth and coloration |
Non-Patent Citations (3)
| Title |
|---|
| CHIARETTI ANTONIO ET AL: "Neuroprotective role of nerve growth factor in hypoxicischemic injury. From brain to skin.", ARCHIVES ITALIENNES DE BIOLOGIE JUN 2011 LNKD- DOI:10.4449/AIB.V149I2.1364 PUBMED:21702000, vol. 149, no. 2, June 2011 (2011-06-01), pages 275 - 282, XP002679577, ISSN: 0003-9829 * |
| CS WU ET AL: "Basic Fibroblast Growth Factor Promotes Melanocyte Migration via Increased Expression of p125FAK on Melanocytes", ACTA DERMATO-VENEREOLOGICA, vol. 86, no. 6, 1 January 2006 (2006-01-01), pages 498 - 502, XP055032253, ISSN: 0001-5555, DOI: 10.2340/00015555-0161 * |
| HSIN-SU YU ET AL: "Helium-Neon Laser Irradiation Stimulates Migration and Proliferation in Melanocytes and Induces Repigmentation in Segmental-Type Vitiligo", JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 120, no. 1, 1 January 2003 (2003-01-01), pages 56 - 64, XP055031758, ISSN: 0022-202X, DOI: 10.1046/j.1523-1747.2003.12011.x * |
Also Published As
| Publication number | Publication date |
|---|---|
| ES2748866T3 (es) | 2020-03-18 |
| WO2013065078A3 (en) | 2014-01-09 |
| JP2014532694A (ja) | 2014-12-08 |
| US9402906B2 (en) | 2016-08-02 |
| CA2854271C (en) | 2018-09-11 |
| WO2013065078A2 (en) | 2013-05-10 |
| CA2854271A1 (en) | 2013-05-10 |
| EP2773318A2 (en) | 2014-09-10 |
| US20140242007A1 (en) | 2014-08-28 |
| JP6130846B2 (ja) | 2017-05-17 |
| IL232419A0 (en) | 2014-06-30 |
| EP2773318B1 (en) | 2019-08-07 |
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