JP2014532060A5 - - Google Patents

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Publication number
JP2014532060A5
JP2014532060A5 JP2014534626A JP2014534626A JP2014532060A5 JP 2014532060 A5 JP2014532060 A5 JP 2014532060A5 JP 2014534626 A JP2014534626 A JP 2014534626A JP 2014534626 A JP2014534626 A JP 2014534626A JP 2014532060 A5 JP2014532060 A5 JP 2014532060A5
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JP
Japan
Prior art keywords
alkyl
substituted
heterocycloalkyl
halo
haloalkyl
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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JP2014534626A
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English (en)
Japanese (ja)
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JP2014532060A (ja
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Priority claimed from PCT/US2012/058298 external-priority patent/WO2013052417A1/en
Publication of JP2014532060A publication Critical patent/JP2014532060A/ja
Publication of JP2014532060A5 publication Critical patent/JP2014532060A5/ja
Pending legal-status Critical Current

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JP2014534626A 2011-10-03 2012-10-01 癌を治療するためのピロロピリミジン化合物 Pending JP2014532060A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161542392P 2011-10-03 2011-10-03
US61/542,392 2011-10-03
US201161547183P 2011-10-14 2011-10-14
US61/547,183 2011-10-14
PCT/US2012/058298 WO2013052417A1 (en) 2011-10-03 2012-10-01 Pyrrolopyrimidine compounds for the treatment of cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016255095A Division JP6316925B2 (ja) 2011-10-03 2016-12-28 癌を治療するためのピロロピリミジン化合物

Publications (2)

Publication Number Publication Date
JP2014532060A JP2014532060A (ja) 2014-12-04
JP2014532060A5 true JP2014532060A5 (cg-RX-API-DMAC7.html) 2016-03-03

Family

ID=48044101

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2014534626A Pending JP2014532060A (ja) 2011-10-03 2012-10-01 癌を治療するためのピロロピリミジン化合物
JP2016255095A Active JP6316925B2 (ja) 2011-10-03 2016-12-28 癌を治療するためのピロロピリミジン化合物

Family Applications After (1)

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JP2016255095A Active JP6316925B2 (ja) 2011-10-03 2016-12-28 癌を治療するためのピロロピリミジン化合物

Country Status (13)

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US (3) US9273056B2 (cg-RX-API-DMAC7.html)
EP (1) EP2763988B1 (cg-RX-API-DMAC7.html)
JP (2) JP2014532060A (cg-RX-API-DMAC7.html)
KR (1) KR102063098B1 (cg-RX-API-DMAC7.html)
CN (1) CN103958510B (cg-RX-API-DMAC7.html)
AU (1) AU2012318896B2 (cg-RX-API-DMAC7.html)
BR (1) BR112014007788A2 (cg-RX-API-DMAC7.html)
CA (1) CA2850617A1 (cg-RX-API-DMAC7.html)
ES (1) ES2650630T3 (cg-RX-API-DMAC7.html)
IL (1) IL231835A0 (cg-RX-API-DMAC7.html)
MX (1) MX2014004086A (cg-RX-API-DMAC7.html)
RU (1) RU2631655C2 (cg-RX-API-DMAC7.html)
WO (1) WO2013052417A1 (cg-RX-API-DMAC7.html)

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EP2571361A4 (en) 2010-05-19 2013-11-13 Univ North Carolina PYRAZOLOPYRIMIDINE COMPOUNDS FOR CANCER TREATMENT
AU2012318896B2 (en) 2011-10-03 2017-03-02 The University Of North Carolina At Chapel Hill Pyrrolopyrimidine compounds for the treatment of cancer
EP2852579A4 (en) 2012-05-22 2015-12-30 Univ North Carolina PYRIMIDINE COMPOUNDS FOR CANCER TREATMENT
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US9562047B2 (en) 2012-10-17 2017-02-07 The University Of North Carolina At Chapel Hill Pyrazolopyrimidine compounds for the treatment of cancer
EP2925752A4 (en) 2012-11-27 2016-06-01 Univ North Carolina PYRIMIDINE COMPOUNDS FOR CANCER TREATMENT
US9555031B2 (en) 2014-04-11 2017-01-31 The University Of North Carolina At Chapel Hill Therapeutic uses of selected pyrrolopyrimidine compounds with anti-mer tyrosine kinase activity
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ES3031110T3 (en) 2018-06-29 2025-07-04 Incyte Corp Formulations of an axl/mer inhibitor
KR102163494B1 (ko) * 2018-10-26 2020-10-08 한국과학기술연구원 단백질 키나아제 저해제인 헤테로방향족 매크로시클릭 유도체
CN114127071B (zh) * 2019-04-02 2024-03-22 梅里克斯股份有限公司 激酶抑制剂的多晶型、含有该化合物的药物组合物、制备方法、及应用
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CN112043710A (zh) * 2020-09-28 2020-12-08 广州智睿医药科技有限公司 一种治疗或预防与lrrk2激酶或异常lrrk2突变激酶活性相关疾病的药物
CN115073469B (zh) * 2021-03-15 2023-12-22 药雅科技(上海)有限公司 吡咯并嘧啶类化合物作为激酶抑制剂的制备及其应用
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US20170202847A1 (en) 2014-04-04 2017-07-20 The University Of North Carolina At Chapel Hill Methods for the treatment of tumors
US9555031B2 (en) 2014-04-11 2017-01-31 The University Of North Carolina At Chapel Hill Therapeutic uses of selected pyrrolopyrimidine compounds with anti-mer tyrosine kinase activity

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