JP2014529406A - 血管周囲薬用細胞の単離および治療的使用 - Google Patents

血管周囲薬用細胞の単離および治療的使用 Download PDF

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JP2014529406A
JP2014529406A JP2014528501A JP2014528501A JP2014529406A JP 2014529406 A JP2014529406 A JP 2014529406A JP 2014528501 A JP2014528501 A JP 2014528501A JP 2014528501 A JP2014528501 A JP 2014528501A JP 2014529406 A JP2014529406 A JP 2014529406A
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bone
pvmcs
cells
umbilical cord
combinations
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JP2014529406A5 (enExample
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カプラン、アーノルド、アイ．
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セーフガードセル テクノロジー インク．
セーフガード セル テクノロジー インク．
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0605—Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B02—CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02C—CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C19/00—Other disintegrating devices or methods
    • B02C19/0056—Other disintegrating devices or methods specially adapted for specific materials not otherwise provided for
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0668—Mesenchymal stem cells from other natural sources
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
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  • Wood Science & Technology (AREA)
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  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Gynecology & Obstetrics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Reproductive Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
JP2014528501A 2011-08-29 2012-08-27 血管周囲薬用細胞の単離および治療的使用 Pending JP2014529406A (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201161528556P 2011-08-29 2011-08-29
US201161528563P 2011-08-29 2011-08-29
US201161528567P 2011-08-29 2011-08-29
US61/528,556 2011-08-29
US61/528,563 2011-08-29
US61/528,567 2011-08-29

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JP2014529406A true JP2014529406A (ja) 2014-11-13
JP2014529406A5 JP2014529406A5 (enExample) 2015-10-29

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JP2014528501A Pending JP2014529406A (ja) 2011-08-29 2012-08-27 血管周囲薬用細胞の単離および治療的使用

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US (1) US20140314869A1 (enExample)
EP (1) EP2751256A4 (enExample)
JP (1) JP2014529406A (enExample)
AU (1) AU2012300221A1 (enExample)
CA (1) CA2853910A1 (enExample)
SG (1) SG11201401038VA (enExample)
WO (1) WO2013033043A1 (enExample)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10758573B2 (en) 2015-06-09 2020-09-01 President And Fellows Of Harvard College Compositions and methods for enrichment of cells
CN105505862B (zh) * 2015-12-29 2019-01-18 江苏省原子医学研究所 一种采用机械分离法提取骨组织中的成骨细胞的方法
AU2018283372B2 (en) 2017-06-16 2024-06-13 Avery Therapeutics, Inc. Three dimensional tissue compositions and methods of use
CN111601606A (zh) 2017-11-29 2020-08-28 菲格内有限责任公司 用于活化的成纤维细胞与免疫细胞的相互作用及其用途
WO2020092321A1 (en) * 2018-10-29 2020-05-07 Avery Therapeutics, Inc. Compositions and methods for cryopreservation and reconstitution of engineered tissues
EP3921029B1 (en) * 2019-02-07 2025-07-30 Baylor College of Medicine Composition comprising ccl5 for use in treating bone break, bone fracture, bone degeneration and osteoporosis
CN115772494B (zh) * 2021-09-06 2025-10-21 上海交通大学医学院附属第九人民医院 一种牙槽骨组织消化液及其在牙槽骨细胞分离中的用途和方法

Family Cites Families (8)

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Publication number Priority date Publication date Assignee Title
US4619989A (en) * 1981-05-05 1986-10-28 The Regents Of The University Of Cal. Bone morphogenetic protein composition
AU2003901668A0 (en) * 2003-03-28 2003-05-01 Medvet Science Pty. Ltd. Non-haemopoietic precursor cells
US20030095993A1 (en) * 2000-01-28 2003-05-22 Hanne Bentz Gel-infused sponges for tissue repair and augmentation
GB0600972D0 (en) * 2006-01-18 2006-03-01 Univ Leeds Enrichment of cells
US20070264239A1 (en) * 2006-05-10 2007-11-15 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Isolation of pericytes
EP2288359B1 (en) * 2008-04-21 2019-10-02 Tissue Regeneration Therapeutics Inc. Genetically modified human umbilical cord perivascular cells for prophylaxis against or treatment of biological or chemical agents
US8470308B2 (en) * 2009-01-03 2013-06-25 Ray C. Wasielewski Enhanced medical implant comprising disrupted tooth pulp and tooth particles
US20120148546A1 (en) * 2009-08-17 2012-06-14 Technion Research & Development Foundation Ltd. Pericyte progenitor cells and methods of generating and using same

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ARTHRITIS RHEUM., vol. 62, no. 7, JPN6016028043, 2010, pages 1944 - 1954, ISSN: 0003364471 *
BLOOD, vol. 104, no. 9, JPN6016028047, 2004, pages 2728 - 2735, ISSN: 0003364473 *
OPEN ORTHOP. J., vol. vol.5, suppl. 2, JPN6016028046, July 2011 (2011-07-01), pages 253 - 260, ISSN: 0003364472 *

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Publication number Publication date
WO2013033043A1 (en) 2013-03-07
AU2012300221A1 (en) 2014-04-17
US20140314869A1 (en) 2014-10-23
EP2751256A1 (en) 2014-07-09
CA2853910A1 (en) 2013-03-07
EP2751256A4 (en) 2015-01-28
SG11201401038VA (en) 2014-07-30

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