JP2014528705A - アセトアセチルＣｏＡシンターゼを用いるイソプレン、イソプレノイド前駆体、及びイソプレノイドの生産 - Google Patents

アセトアセチルＣｏＡシンターゼを用いるイソプレン、イソプレノイド前駆体、及びイソプレノイドの生産 Download PDF

Info

Publication number
JP2014528705A
JP2014528705A JP2014524145A JP2014524145A JP2014528705A JP 2014528705 A JP2014528705 A JP 2014528705A JP 2014524145 A JP2014524145 A JP 2014524145A JP 2014524145 A JP2014524145 A JP 2014524145A JP 2014528705 A JP2014528705 A JP 2014528705A
Authority
JP
Japan
Prior art keywords
polypeptide
coa
cell
synthase
nucleic acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2014524145A
Other languages
English (en)
Japanese (ja)
Other versions
JP2014528705A5 (https=
Inventor
アルドア、イラナ・エス
ベック、ザッカリー・キュー
ミラー、マイケル・シー
ペレス、キャロライン・エム
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Goodyear Tire and Rubber Co
Original Assignee
Goodyear Tire and Rubber Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Goodyear Tire and Rubber Co filed Critical Goodyear Tire and Rubber Co
Publication of JP2014528705A publication Critical patent/JP2014528705A/ja
Publication of JP2014528705A5 publication Critical patent/JP2014528705A5/ja
Withdrawn legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F36/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds
    • C08F36/02—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds the radical having only two carbon-to-carbon double bonds
    • C08F36/04—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds the radical having only two carbon-to-carbon double bonds conjugated
    • C08F36/08—Isoprene
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01194—Acetoacetyl-CoA synthase (2.3.1.194)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/03—Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
    • C12Y402/03027—Isoprene synthase (4.2.3.27)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/30—Fuel from waste, e.g. synthetic alcohol or diesel
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2014524145A 2011-08-04 2012-08-03 アセトアセチルＣｏＡシンターゼを用いるイソプレン、イソプレノイド前駆体、及びイソプレノイドの生産 Withdrawn JP2014528705A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161515300P 2011-08-04 2011-08-04
US61/515,300 2011-08-04
PCT/US2012/049659 WO2013020118A1 (en) 2011-08-04 2012-08-03 Production of isoprene, isoprenoid precursors, and isoprenoids using acetoacetyl-coa synthase

Publications (2)

Publication Number Publication Date
JP2014528705A true JP2014528705A (ja) 2014-10-30
JP2014528705A5 JP2014528705A5 (https=) 2015-09-17

Family

ID=46724633

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014524145A Withdrawn JP2014528705A (ja) 2011-08-04 2012-08-03 アセトアセチルＣｏＡシンターゼを用いるイソプレン、イソプレノイド前駆体、及びイソプレノイドの生産

Country Status (10)

Country Link
US (1) US20130122562A1 (https=)
EP (1) EP2739658A1 (https=)
JP (1) JP2014528705A (https=)
CN (1) CN104039844A (https=)
AU (1) AU2012289886A1 (https=)
BR (1) BR112014002661A2 (https=)
CA (1) CA2844064A1 (https=)
HK (1) HK1199048A1 (https=)
SG (1) SG2014007991A (https=)
WO (1) WO2013020118A1 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017131488A1 (ko) * 2016-01-26 2017-08-03 경상대학교산학협력단 이소프렌의 생산 방법
JP2018014960A (ja) * 2016-07-29 2018-02-01 横浜ゴム株式会社 発現ベクター、形質転換された藻類、形質転換された珪藻、及び、ポリヌクレオチド
KR101936825B1 (ko) * 2016-01-26 2019-01-11 경상대학교산학협력단 이소프렌의 생산 방법

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9663801B2 (en) 2011-06-17 2017-05-30 Invista North America S.A.R.L. Methods of producing four carbon molecules
US9422578B2 (en) 2011-06-17 2016-08-23 Invista North America S.A.R.L. Methods for biosynthesizing 1,3 butadiene
CN104039974B (zh) 2011-11-09 2016-10-12 阿迈瑞斯公司 乙酰辅酶a衍生的类异戊二烯的生产
US20140128645A1 (en) * 2011-12-23 2014-05-08 The Goodyear Tire & Rubber Company Enhanced production of isoprene using marine bacterial cells
US20130323820A1 (en) 2012-06-01 2013-12-05 Lanzatech New Zealand Limited Recombinant microorganisms and uses therefor
SG11201501013PA (en) 2012-08-10 2015-04-29 Opx Biotechnologies Inc Microorganisms and methods for the production of fatty acids and fatty acid derived products
CN104903455A (zh) 2012-11-28 2015-09-09 英威达技术有限责任公司 用于异丁烯生物合成的方法
WO2014106122A1 (en) * 2012-12-31 2014-07-03 Genomatica, Inc. Compositions and methods for bio-butadiene production screening
WO2014146026A1 (en) 2013-03-15 2014-09-18 Opx Biotechnologies, Inc. Bioproduction of chemicals
US10294496B2 (en) 2013-07-19 2019-05-21 Invista North America S.A.R.L. Methods for biosynthesizing 1,3 butadiene
CN106795483A (zh) 2013-07-19 2017-05-31 嘉吉公司 用于生产脂肪酸和脂肪酸衍生产物的微生物及方法
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
US9862973B2 (en) 2013-08-05 2018-01-09 Invista North America S.A.R.L. Methods for biosynthesis of isoprene
US10533193B2 (en) 2013-08-05 2020-01-14 Invista North America S.A.R.L. Methods for biosynthesis of isobutene
BR112016002494A2 (pt) 2013-08-05 2017-09-05 Greenlight Biosciences Inc Proteí-nas construídas com um sítio de clivagem de protease, ácido nucléico, vetor, célula e processo de engenharia de uma proteína recombinante e de um grande número de variantes de ácidos nucleicos que codificam proteínas recombinantes
US10648004B2 (en) 2014-02-20 2020-05-12 Danisco Us Inc. Recombinant microorganisms for the enhanced production of mevalonate, isoprene, isoprenoid precursors, isoprenoids, and acetyl-CoA-derived products
US20170152531A1 (en) 2014-06-16 2017-06-01 North America S.A.R.L. Process for producing glutarate and glutaric acid methyl ester
EP2993228B1 (en) 2014-09-02 2019-10-09 Cargill, Incorporated Production of fatty acid esters
CN107815424B (zh) * 2016-09-12 2021-03-05 华东理工大学 一种产柠檬烯的解脂耶氏酵母基因工程菌及其应用
WO2018129275A1 (en) 2017-01-06 2018-07-12 Greenlight Biosciences, Inc. Cell-free production of sugars
EP3577227A4 (en) 2017-02-02 2020-12-30 Cargill Inc. GENETICALLY MODIFIED CELLS PRODUCING C6-C10 FATTY ACID DERIVATIVES
CN107118988B (zh) * 2017-05-17 2020-11-24 重庆理工大学 高效复合沼气发酵催化剂
US11634733B2 (en) 2017-06-30 2023-04-25 Inv Nylon Chemicals Americas, Llc Methods, materials, synthetic hosts and reagents for the biosynthesis of hydrocarbons and derivatives thereof
US11162115B2 (en) 2017-06-30 2021-11-02 Inv Nylon Chemicals Americas, Llc Methods, synthetic hosts and reagents for the biosynthesis of hydrocarbons
US11505809B2 (en) 2017-09-28 2022-11-22 Inv Nylon Chemicals Americas Llc Organisms and biosynthetic processes for hydrocarbon synthesis
CN109797173B (zh) * 2019-03-27 2022-09-20 山东泓达生物科技有限公司 一种β-法尼烯的生产方法
WO2023028459A1 (en) * 2021-08-24 2023-03-02 Lanzatech, Inc. Microbial fermentation for the production of isoprenoid alcohols and derivatives
CN115820527B (zh) * 2022-12-09 2024-03-19 天津大学 一种生产甲羟戊酸的重组盐单胞菌及构建方法与应用
EP4702154A2 (en) * 2023-04-11 2026-03-04 Allozymes Pte Ltd Methods and compositions for producing a carotenoid or terpenoid
CN116925991B (zh) * 2023-07-28 2024-08-09 天津大学 高产甲羟戊酸的重组盐单胞菌菌株及构建方法与应用
CN117965414B (zh) * 2024-04-01 2024-06-14 北京微构工场生物技术有限公司 一种重组盐单胞菌及其在生产异戊二烯中的应用
CN118773228A (zh) * 2024-06-25 2024-10-15 广州新鑫生物科技有限公司 一种改造大肠杆菌代谢通路以提高乙酰辅酶a合成效率的方法
CN121086968A (zh) * 2025-11-05 2025-12-09 珠海麦得发生物科技股份有限公司 一种重组微生物及其构建方法和在生产3-羟基丁酸或聚羟基脂肪酸酯中的应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008061506A (ja) * 2006-09-04 2008-03-21 Adeka Corp 新規なアセトアセチルＣｏＡ合成酵素、それをコードするＤＮＡ配列、当該酵素の製造方法および当該酵素を利用したメバロン酸の製造方法
WO2010078457A2 (en) * 2008-12-30 2010-07-08 Danisco Us Inc. Methods of producing isoprene and a co-product
WO2011075748A1 (en) * 2009-12-22 2011-06-23 Danisco Us Inc. Membrane bioreactor for increased production of isoprene gas
WO2011079314A2 (en) * 2009-12-23 2011-06-30 Danisco Us Inc. Compositions and methods of pgl for the increased production of isoprene

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19629568C1 (de) 1996-07-15 1998-01-08 Fraunhofer Ges Forschung Verfahren zur Herstellung von Isopren
US7172886B2 (en) 2001-12-06 2007-02-06 The Regents Of The University Of California Biosynthesis of isopentenyl pyrophosphate
JPWO2003095651A1 (ja) 2002-05-10 2005-09-15 協和醗酵工業株式会社 メバロン酸の製造方法
KR101148255B1 (ko) 2002-10-04 2012-08-08 다니스코 유에스 인크. 고수율을 갖는 1,3-프로판디올의 생물학적 제조 방법
RU2004124226A (ru) 2004-08-10 2006-01-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) Использование фосфокетолазы для продукции полезных метаболитов
WO2007140339A2 (en) 2006-05-26 2007-12-06 Amyris Biotechnologies, Inc. Production of isoprenoids
CN105368764B (zh) 2007-12-13 2019-03-12 丹尼斯科美国公司 用于生产异戊二烯的组合物和方法
US20110045563A1 (en) 2008-02-06 2011-02-24 The Regents Of The University Of California Short chain volatile isoprene hydrocarbon production using the mevalonic acid pathway in genetically engineered yeast and fungi
WO2009132220A2 (en) 2008-04-23 2009-10-29 Danisco Us Inc. Isoprene synthase variants for improved microbial production of isoprene
US7632995B2 (en) 2008-05-09 2009-12-15 Monsanto Technology Llc Plants and seeds of hybrid corn variety CH852179
MX318543B (es) 2008-07-02 2014-03-18 Danisco Us Inc Composiciones y metodos para producir isopreno libre de hidrocarburos de c5 bajo condicion de desacoplamiento y/o intervalos de operacion seguros.
HU3516U (en) 2008-07-31 2008-11-28 Zoltan Kuthi Anti-theft protection of draining for fuel tanks
EP2344629B1 (en) 2008-09-15 2018-01-24 Danisco US Inc. Systems using cell culture for production of isoprene
WO2010031062A1 (en) 2008-09-15 2010-03-18 Danisco Us Inc. Increased isoprene production using the archaeal lower mevalonate pathway
EP2340312A2 (en) 2008-09-15 2011-07-06 Danisco US Inc. Conversion of prenyl derivatives to isoprene
CA2737223A1 (en) 2008-09-15 2010-03-18 Danisco Us Inc. Reduction of carbon dioxide emission during isoprene production by fermentation
US20100297749A1 (en) 2009-04-21 2010-11-25 Sapphire Energy, Inc. Methods and systems for biofuel production
AU2010238770A1 (en) 2009-04-23 2011-11-03 Danisco Us Inc. Three-dimensional structure of isoprene synthase and its use thereof for generating variants
JP4760951B2 (ja) * 2009-05-08 2011-08-31 トヨタ自動車株式会社 ブタノール生産能を有する組換え微生物及びブタノールの製造方法
TW201412988A (zh) 2009-06-17 2014-04-01 Danisco Us Inc 使用ｄｘｐ及ｍｖａ途徑之改良之異戊二烯製造
TWI434921B (zh) 2009-06-17 2014-04-21 Danisco Us Inc 從生物異戊二烯組合物製造燃料成分之方法及系統
US20120252054A1 (en) 2009-09-15 2012-10-04 Sapphire Energy Inc System for transformation of the chloroplast genome of scenedesmus sp. and dunaliella sp.
WO2011116279A2 (en) * 2010-03-18 2011-09-22 William Marsh Rice University Bacteria and method for synthesizing fatty acids
CA2816306A1 (en) 2010-10-27 2012-05-03 Danisco Us Inc. Isoprene synthase variants for improved production of isoprene

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008061506A (ja) * 2006-09-04 2008-03-21 Adeka Corp 新規なアセトアセチルＣｏＡ合成酵素、それをコードするＤＮＡ配列、当該酵素の製造方法および当該酵素を利用したメバロン酸の製造方法
WO2010078457A2 (en) * 2008-12-30 2010-07-08 Danisco Us Inc. Methods of producing isoprene and a co-product
WO2011075748A1 (en) * 2009-12-22 2011-06-23 Danisco Us Inc. Membrane bioreactor for increased production of isoprene gas
WO2011079314A2 (en) * 2009-12-23 2011-06-30 Danisco Us Inc. Compositions and methods of pgl for the increased production of isoprene

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
化学と生物, 2011.05.01, VOL.49, NO.5, PP.305-306, JPN6016041159, ISSN: 0003426523 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017131488A1 (ko) * 2016-01-26 2017-08-03 경상대학교산학협력단 이소프렌의 생산 방법
KR101936825B1 (ko) * 2016-01-26 2019-01-11 경상대학교산학협력단 이소프렌의 생산 방법
JP2018014960A (ja) * 2016-07-29 2018-02-01 横浜ゴム株式会社 発現ベクター、形質転換された藻類、形質転換された珪藻、及び、ポリヌクレオチド

Also Published As

Publication number Publication date
AU2012289886A1 (en) 2014-02-20
CN104039844A (zh) 2014-09-10
WO2013020118A1 (en) 2013-02-07
BR112014002661A2 (pt) 2019-09-24
HK1199048A1 (en) 2015-06-19
US20130122562A1 (en) 2013-05-16
CA2844064A1 (en) 2013-02-07
SG2014007991A (en) 2014-03-28
EP2739658A1 (en) 2014-06-11

Similar Documents

Publication Publication Date Title
US10975394B2 (en) Recombinant microorganisms for enhanced production of mevalonate, isoprene, and isoprenoids
US10364443B2 (en) Production of mevalonate, isoprene, and isoprenoids using genes encoding polypeptides having thiolase, HMG-CoA synthase and HMG-CoA reductase enzymatic activities
JP2014528705A (ja) アセトアセチルＣｏＡシンターゼを用いるイソプレン、イソプレノイド前駆体、及びイソプレノイドの生産
JP6639606B2 (ja) メバロン酸、イソプレノイド前駆体、及びイソプレンの産生におけるホスホケトラーゼの使用
US20140335576A1 (en) Methods for increasing microbial production of isoprene, isoprenoids, and isoprenoid precursor molecules using glucose and acetate co-metabolism

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20150727

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20150727

A761 Written withdrawal of application

Free format text: JAPANESE INTERMEDIATE CODE: A761

Effective date: 20160316

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20161025

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20170620