JP2014527506A - 糖尿病治療のための組み合わせ - Google Patents
糖尿病治療のための組み合わせ Download PDFInfo
- Publication number
- JP2014527506A JP2014527506A JP2014513476A JP2014513476A JP2014527506A JP 2014527506 A JP2014527506 A JP 2014527506A JP 2014513476 A JP2014513476 A JP 2014513476A JP 2014513476 A JP2014513476 A JP 2014513476A JP 2014527506 A JP2014527506 A JP 2014527506A
- Authority
- JP
- Japan
- Prior art keywords
- combination
- metformin
- diabetes
- ascorbic acid
- pharmaceutical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
- A61K31/37—Coumarins, e.g. psoralen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Endocrinology (AREA)
- Medical Informatics (AREA)
- Obesity (AREA)
- Mycology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2011122374/15A RU2451506C1 (ru) | 2011-06-02 | 2011-06-02 | Комбинация для лечения сахарного диабета и его осложнений |
RU2011122374 | 2011-06-02 | ||
PCT/RU2012/000254 WO2012166008A1 (en) | 2011-06-02 | 2012-04-05 | Combination for treatment of diabetes mellitus |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2014527506A true JP2014527506A (ja) | 2014-10-16 |
JP2014527506A5 JP2014527506A5 (ko) | 2015-05-14 |
Family
ID=46231593
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2014513476A Pending JP2014527506A (ja) | 2011-06-02 | 2012-04-05 | 糖尿病治療のための組み合わせ |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP2714022A1 (ko) |
JP (1) | JP2014527506A (ko) |
KR (1) | KR101567660B1 (ko) |
CN (1) | CN103402506A (ko) |
EA (1) | EA028394B1 (ko) |
RU (1) | RU2451506C1 (ko) |
WO (1) | WO2012166008A1 (ko) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2548731C2 (ru) * | 2012-10-24 | 2015-04-20 | Федеральное Государственное Бюджетное Образовательное Учреждение Высшего Профессионального Образования "Новосибирский Государственный Педагогический Университет" | Средство и способ комплексной терапии больных сахарным диабетом |
CA2912881A1 (en) | 2013-05-24 | 2014-11-27 | Otsuka Pharmaceutical Co., Ltd. | Pharmaceutical combination comprising metformin and dihydroquercetin and its use for the treatment of cancer |
US10442610B2 (en) | 2014-03-11 | 2019-10-15 | Starbucks Corporation | Pod-based restrictors and methods |
CN105902761A (zh) * | 2016-06-16 | 2016-08-31 | 河南中医学院 | 一种槐花珍在制备治疗高血糖和糖尿病药物中的应用 |
FR3062795B1 (fr) * | 2017-02-16 | 2019-06-07 | Valbiotis | Principe actif pharmaceutique et utilisation en particulier dans la prevention et le traitement des dereglements metaboliques chez l'homme et l'animal. |
RU2687256C1 (ru) * | 2018-03-26 | 2019-05-08 | Федеральное Государственное бюджетное образовательное учреждение высшего образования Дагестанский государственный медицинский университет Министерства здравоохранения Российской Федерации Даггосмедуниверситет | Способ персонализированного лечения хронической болезни почек у больных с диабетической нефропатией |
Citations (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002080362A (ja) * | 2000-06-21 | 2002-03-19 | Kao Corp | Ppar依存的遺伝子転写活性化剤 |
JP2003300904A (ja) * | 2002-04-05 | 2003-10-21 | National Cardiovascular Center | 循環器系障害の進展を抑制する医薬組成物 |
WO2007007757A1 (ja) * | 2005-07-12 | 2007-01-18 | Daiichi Sankyo Company, Limited | PPARγアゴニストを含有する医薬組成物 |
JP2007505854A (ja) * | 2003-09-23 | 2007-03-15 | ディーエスエム アイピー アセッツ ビー.ブイ. | 糖尿病の治療および予防用組成物 |
JP2007509035A (ja) * | 2003-10-10 | 2007-04-12 | レスバーロジックス コーポレイション | Egr−1エンハンサー要素に関連する疾患の処置 |
JP2007262050A (ja) * | 2005-12-16 | 2007-10-11 | National Institute Of Advanced Industrial & Technology | アディポネクチン産生増強剤 |
JP2008189681A (ja) * | 2008-03-31 | 2008-08-21 | Kao Corp | 脂質代謝改善剤 |
WO2010089874A1 (ja) * | 2009-02-05 | 2010-08-12 | フジッコ株式会社 | PPAR-γ発現増強剤、アディポネクチン産生促進剤、UCP活性剤およびそれらを用いた医薬品・飲食品 |
WO2010118789A1 (en) * | 2009-04-17 | 2010-10-21 | Dsm Ip Assets B.V. | Hydroxytyrosol combinations for enhancing mitochondrial function and energy production |
JP2011063557A (ja) * | 2009-09-18 | 2011-03-31 | Lion Corp | Ppar活性化剤 |
WO2011036316A2 (es) * | 2009-09-23 | 2011-03-31 | Probelte Pharma, Sa | Uso de extractos vegetales como prebióticos, composiciones y alimentos que los contienen |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6399658B1 (en) * | 1996-12-24 | 2002-06-04 | Sumitomo Pharmaceuticals Co., Ltd. | Composition containing ascorbic acid |
PT974356E (pt) | 1998-07-15 | 2004-02-27 | Merck Sante Sas | Comprimidos compreendendo uma combinacao de metformina e de glibenclamida |
KR20000019716A (ko) * | 1998-09-15 | 2000-04-15 | 박호군 | 바이오플라보노이드 화합물을 포함하는 혈당 강하용 조성물 |
ITMI20002019A1 (it) | 1999-09-17 | 2002-03-15 | Novartis Ag | Metodo per il trattemento dei disturbi metabolici, in particolare diabete oppure una malattia oppure una condizione associate con il diabete |
DE60135760D1 (de) * | 2000-08-01 | 2008-10-23 | Oryza Oil & Fat Chem | Nachtkerzensamenextrakte als inhibitoren der zuckerabsorption und deren herstellungsprozess |
RU2284829C2 (ru) * | 2004-12-16 | 2006-10-10 | Пятигорская государственная фармацевтическая академия | Антидиабетический сбор |
WO2006079056A1 (en) * | 2005-01-20 | 2006-07-27 | Stephen Holt | Herbal compositions containing hoodia |
JP5246834B2 (ja) * | 2005-12-27 | 2013-07-24 | 独立行政法人産業技術総合研究所 | アディポネクチン産生強化剤 |
CN101176786A (zh) * | 2006-11-08 | 2008-05-14 | 中国科学院上海生命科学研究院 | 增加胰岛素敏感性的方法和组合物 |
RU2413528C2 (ru) | 2007-01-18 | 2011-03-10 | Открытое Акционерное Общество "Валента Фармацевтика" | Лекарственный препарат для лечения сахарного диабета на основе экзенатида и даларгина, применение и способ лечения |
TW200903710A (en) | 2007-07-11 | 2009-01-16 | Promos Technologies Inc | Manufacturing method for shallow trench isolation |
US20090175973A1 (en) * | 2007-09-05 | 2009-07-09 | Nina Vikhrieva | Coffee cherry compositions and methods for their use in the treatment of diabetes and diabetes related disorders |
CN101250106B (zh) * | 2008-03-27 | 2011-05-18 | 北京市农林科学院 | 一种提取绿原酸的方法 |
RU2378003C1 (ru) | 2008-06-06 | 2010-01-10 | Сергей Юрьевич Лешков | Фармацевтическая композиция на основе экстракта зеленой ягоды кофе, способ получения и применения |
WO2010048114A1 (en) | 2008-10-22 | 2010-04-29 | Metaproteomics, Llc | Novel mitochondrial uncoupling methods and compositions for enhancing adipocyte thermogenesis |
EP2432320A4 (en) * | 2009-05-20 | 2013-03-06 | Nutracryst Therapeutics Private Ltd | PHARMACEUTICAL CO-CRYSTALS OF QUERCÉTINE |
CN101851221B (zh) * | 2010-05-27 | 2012-09-05 | 东北林业大学 | 一种从落叶松中制备二氢槲皮素的方法 |
-
2011
- 2011-06-02 RU RU2011122374/15A patent/RU2451506C1/ru not_active IP Right Cessation
-
2012
- 2012-04-05 KR KR1020137032709A patent/KR101567660B1/ko not_active IP Right Cessation
- 2012-04-05 EP EP12738248.9A patent/EP2714022A1/en not_active Withdrawn
- 2012-04-05 JP JP2014513476A patent/JP2014527506A/ja active Pending
- 2012-04-05 EA EA201301308A patent/EA028394B1/ru not_active IP Right Cessation
- 2012-04-05 WO PCT/RU2012/000254 patent/WO2012166008A1/en active Application Filing
- 2012-04-05 CN CN2012800085850A patent/CN103402506A/zh active Pending
Patent Citations (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002080362A (ja) * | 2000-06-21 | 2002-03-19 | Kao Corp | Ppar依存的遺伝子転写活性化剤 |
JP2003300904A (ja) * | 2002-04-05 | 2003-10-21 | National Cardiovascular Center | 循環器系障害の進展を抑制する医薬組成物 |
JP2007505854A (ja) * | 2003-09-23 | 2007-03-15 | ディーエスエム アイピー アセッツ ビー.ブイ. | 糖尿病の治療および予防用組成物 |
JP2007509035A (ja) * | 2003-10-10 | 2007-04-12 | レスバーロジックス コーポレイション | Egr−1エンハンサー要素に関連する疾患の処置 |
WO2007007757A1 (ja) * | 2005-07-12 | 2007-01-18 | Daiichi Sankyo Company, Limited | PPARγアゴニストを含有する医薬組成物 |
JP2007262050A (ja) * | 2005-12-16 | 2007-10-11 | National Institute Of Advanced Industrial & Technology | アディポネクチン産生増強剤 |
JP2008189681A (ja) * | 2008-03-31 | 2008-08-21 | Kao Corp | 脂質代謝改善剤 |
WO2010089874A1 (ja) * | 2009-02-05 | 2010-08-12 | フジッコ株式会社 | PPAR-γ発現増強剤、アディポネクチン産生促進剤、UCP活性剤およびそれらを用いた医薬品・飲食品 |
WO2010118789A1 (en) * | 2009-04-17 | 2010-10-21 | Dsm Ip Assets B.V. | Hydroxytyrosol combinations for enhancing mitochondrial function and energy production |
JP2011063557A (ja) * | 2009-09-18 | 2011-03-31 | Lion Corp | Ppar活性化剤 |
WO2011036316A2 (es) * | 2009-09-23 | 2011-03-31 | Probelte Pharma, Sa | Uso de extractos vegetales como prebióticos, composiciones y alimentos que los contienen |
Non-Patent Citations (4)
Title |
---|
JPN6016004151; Phytomedicine 16, 2009, 1119-1126 * |
JPN6016004153; Journal of Agricultural and Food Chemistry 59(9), 201105, 5100-5108 * |
JPN6016004155; Tropical Journal of Pharmaceutical Research 6 (1), 2007, 671-678 * |
JPN6016004156; Mol. Nutr. Food Res. 54, 2010, 991-1003 * |
Also Published As
Publication number | Publication date |
---|---|
CN103402506A (zh) | 2013-11-20 |
WO2012166008A1 (en) | 2012-12-06 |
RU2451506C1 (ru) | 2012-05-27 |
EA201301308A1 (ru) | 2014-03-31 |
EA028394B1 (ru) | 2017-11-30 |
EP2714022A1 (en) | 2014-04-09 |
KR20140008452A (ko) | 2014-01-21 |
KR101567660B1 (ko) | 2015-11-10 |
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