JP2014525945A5 - - Google Patents
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- Publication number
- JP2014525945A5 JP2014525945A5 JP2014516321A JP2014516321A JP2014525945A5 JP 2014525945 A5 JP2014525945 A5 JP 2014525945A5 JP 2014516321 A JP2014516321 A JP 2014516321A JP 2014516321 A JP2014516321 A JP 2014516321A JP 2014525945 A5 JP2014525945 A5 JP 2014525945A5
- Authority
- JP
- Japan
- Prior art keywords
- microparticle
- polymer
- poly
- active substance
- fine particles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000011859 microparticle Substances 0.000 claims 15
- 229920000642 polymer Polymers 0.000 claims 7
- 239000010419 fine particle Substances 0.000 claims 6
- 239000013543 active substance Substances 0.000 claims 5
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 claims 4
- 239000002953 phosphate buffered saline Substances 0.000 claims 4
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 3
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 claims 3
- 150000002009 diols Chemical class 0.000 claims 3
- 239000002245 particle Substances 0.000 claims 3
- 229920000233 poly(alkylene oxides) Polymers 0.000 claims 3
- PAPBSGBWRJIAAV-UHFFFAOYSA-N ε-Caprolactone Chemical group O=C1CCCCCO1 PAPBSGBWRJIAAV-UHFFFAOYSA-N 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 2
- 239000013585 weight reducing agent Substances 0.000 claims 2
- 239000000443 aerosol Substances 0.000 claims 1
- 125000005442 diisocyanate group Chemical group 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 229920001610 polycaprolactone Polymers 0.000 claims 1
- 239000004632 polycaprolactone Substances 0.000 claims 1
- 229920002635 polyurethane Polymers 0.000 claims 1
- 239000004814 polyurethane Substances 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- JOYRKODLDBILNP-UHFFFAOYSA-N urethane group Chemical group NC(=O)OCC JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1110601.0 | 2011-06-23 | ||
| GBGB1110601.0A GB201110601D0 (en) | 2011-06-23 | 2011-06-23 | Improved bioresorbable |
| PCT/EP2012/061791 WO2012175538A1 (en) | 2011-06-23 | 2012-06-20 | Bioresorbable microparticles |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014525945A JP2014525945A (ja) | 2014-10-02 |
| JP2014525945A5 true JP2014525945A5 (enExample) | 2015-07-09 |
| JP6073874B2 JP6073874B2 (ja) | 2017-02-01 |
Family
ID=44454499
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014516321A Active JP6073874B2 (ja) | 2011-06-23 | 2012-06-20 | 生体吸収性微粒子 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9919052B2 (enExample) |
| EP (1) | EP2723792B1 (enExample) |
| JP (1) | JP6073874B2 (enExample) |
| CN (1) | CN103649152B (enExample) |
| CA (1) | CA2839625C (enExample) |
| ES (1) | ES2836953T3 (enExample) |
| GB (1) | GB201110601D0 (enExample) |
| WO (1) | WO2012175538A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104107434B (zh) * | 2013-04-18 | 2017-02-01 | 山东绿叶制药有限公司 | 戈舍瑞林缓释微球药物组合物 |
| KR102172140B1 (ko) * | 2019-05-03 | 2020-11-02 | 가톨릭대학교 산학협력단 | 생분해성 폴리우레탄 마이크로스피어 |
| CN111269373B (zh) * | 2020-02-12 | 2022-01-04 | 浙江大学衢州研究院 | 基于共晶的可重塑形状记忆弹性体的制备方法 |
| US20230190657A1 (en) * | 2020-05-22 | 2023-06-22 | Trustees Of Boston University | Methods and compositions for treating a fibrotic disease |
| CN118304459A (zh) * | 2024-04-02 | 2024-07-09 | 宁波宝亭生物科技有限公司 | 一种在体内能够自融合的栓塞微球及其制备和应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ193221A (en) | 1979-03-21 | 1984-08-24 | M P Embrey | Controlled release composition |
| JP3372558B2 (ja) | 1990-09-14 | 2003-02-04 | 中外製薬株式会社 | マイクロカプセル型徐放性製剤及びその製造法 |
| US6007845A (en) * | 1994-07-22 | 1999-12-28 | Massachusetts Institute Of Technology | Nanoparticles and microparticles of non-linear hydrophilic-hydrophobic multiblock copolymers |
| IL140049A0 (en) | 1998-06-05 | 2002-02-10 | Polyganics Bv | Biomedical polyurethane, its preparation and use |
| GB0222522D0 (en) | 2002-09-27 | 2002-11-06 | Controlled Therapeutics Sct | Water-swellable polymers |
| EP1555278A1 (en) * | 2004-01-15 | 2005-07-20 | Innocore Technologies B.V. | Biodegradable multi-block co-polymers |
| WO2006010278A1 (en) | 2004-07-26 | 2006-02-02 | Synthes Gmbh | Biocompatible, biodegradable polyurethane materials with controlled hydrophobic to hydrophilic ratio |
| GB0620685D0 (en) | 2006-10-18 | 2006-11-29 | Controlled Therapeutics Sct | Bioresorbable polymers |
-
2011
- 2011-06-23 GB GBGB1110601.0A patent/GB201110601D0/en not_active Ceased
-
2012
- 2012-06-20 ES ES12728095T patent/ES2836953T3/es active Active
- 2012-06-20 JP JP2014516321A patent/JP6073874B2/ja active Active
- 2012-06-20 CA CA2839625A patent/CA2839625C/en active Active
- 2012-06-20 CN CN201280030959.9A patent/CN103649152B/zh active Active
- 2012-06-20 WO PCT/EP2012/061791 patent/WO2012175538A1/en not_active Ceased
- 2012-06-20 EP EP12728095.6A patent/EP2723792B1/en active Active
- 2012-06-20 US US14/128,487 patent/US9919052B2/en active Active
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