JP2014525448A5 - - Google Patents
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- Publication number
- JP2014525448A5 JP2014525448A5 JP2014528537A JP2014528537A JP2014525448A5 JP 2014525448 A5 JP2014525448 A5 JP 2014525448A5 JP 2014528537 A JP2014528537 A JP 2014528537A JP 2014528537 A JP2014528537 A JP 2014528537A JP 2014525448 A5 JP2014525448 A5 JP 2014525448A5
- Authority
- JP
- Japan
- Prior art keywords
- imidazo
- oxadiazol
- pyridine
- methyl
- methylphenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161530038P | 2011-09-01 | 2011-09-01 | |
| US61/530,038 | 2011-09-01 | ||
| PCT/US2012/052802 WO2013033167A1 (en) | 2011-09-01 | 2012-08-29 | Compounds and compositions as c-kit kinase inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014525448A JP2014525448A (ja) | 2014-09-29 |
| JP2014525448A5 true JP2014525448A5 (enExample) | 2015-10-29 |
| JP6134319B2 JP6134319B2 (ja) | 2017-05-24 |
Family
ID=46829904
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014528537A Active JP6134319B2 (ja) | 2011-09-01 | 2012-08-29 | ｃ−ｋｉｔキナーゼインヒビターとしての化合物及び組成物 |
Country Status (30)
| Country | Link |
|---|---|
| US (3) | US8569283B2 (enExample) |
| EP (1) | EP2751104B1 (enExample) |
| JP (1) | JP6134319B2 (enExample) |
| KR (1) | KR101962495B1 (enExample) |
| CN (1) | CN103797011B (enExample) |
| AP (1) | AP2014007493A0 (enExample) |
| AR (1) | AR087753A1 (enExample) |
| AU (1) | AU2012302042B2 (enExample) |
| BR (1) | BR112014004560A2 (enExample) |
| CA (1) | CA2845169C (enExample) |
| CL (1) | CL2014000492A1 (enExample) |
| CO (1) | CO6900141A2 (enExample) |
| CR (1) | CR20140107A (enExample) |
| CU (1) | CU20140024A7 (enExample) |
| EA (1) | EA026152B1 (enExample) |
| ES (1) | ES2761332T3 (enExample) |
| GT (1) | GT201400034A (enExample) |
| IL (1) | IL231227A0 (enExample) |
| MA (1) | MA35460B1 (enExample) |
| MX (1) | MX339937B (enExample) |
| PE (1) | PE20140909A1 (enExample) |
| PH (1) | PH12014500372A1 (enExample) |
| PL (1) | PL2751104T3 (enExample) |
| PT (1) | PT2751104T (enExample) |
| SG (1) | SG2014014369A (enExample) |
| TN (1) | TN2014000068A1 (enExample) |
| TW (1) | TW201313717A (enExample) |
| UY (1) | UY34301A (enExample) |
| WO (1) | WO2013033167A1 (enExample) |
| ZA (1) | ZA201401175B (enExample) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6134319B2 (ja) | 2011-09-01 | 2017-05-24 | ノバルティス アーゲー | ｃ−ｋｉｔキナーゼインヒビターとしての化合物及び組成物 |
| US9199981B2 (en) * | 2011-09-01 | 2015-12-01 | Novartis Ag | Compounds and compositions as C-kit kinase inhibitors |
| EP3007689B1 (en) | 2013-01-10 | 2018-03-07 | Pulmokine, Inc. | Non-selective kinase inhibitors |
| US9242969B2 (en) | 2013-03-14 | 2016-01-26 | Novartis Ag | Biaryl amide compounds as kinase inhibitors |
| EP3054937B1 (en) | 2013-10-11 | 2023-07-26 | Pulmokine, Inc. | Spray dry formulations |
| US20150288928A1 (en) * | 2014-04-08 | 2015-10-08 | Sony Corporation | Security camera system use of object location tracking data |
| CN105384738B (zh) * | 2014-08-21 | 2017-08-29 | 上海科州药物研发有限公司 | 作为蛋白激酶抑制剂的杂环类化合物及其制备方法和用途 |
| UY36294A (es) | 2014-09-12 | 2016-04-29 | Novartis Ag | Compuestos y composiciones como inhibidores de quinasa |
| BR112017028318B1 (pt) | 2015-07-02 | 2024-02-20 | Janssen Sciences Ireland Uc | Composto antibacteriano, seu uso, processo para sua preparação,produto que o contém, composição farmacêutica e combinação |
| US10474987B2 (en) * | 2015-08-05 | 2019-11-12 | Whirlpool Corporation | Object recognition system for an appliance and method for managing household inventory of consumables |
| WO2017214413A1 (en) * | 2016-06-08 | 2017-12-14 | Chrysalis, Inc. | Imidazo[1,2-a]pyridine derivatives as histone demethylase inhibitors |
| EP3472158A1 (en) | 2016-06-16 | 2019-04-24 | Janssen Sciences Ireland Unlimited Company | Heterocyclic compounds as antibacterials |
| CA3025727A1 (en) | 2016-06-16 | 2017-12-21 | Janssen Sciences Ireland Unlimited Company | Heterocyclic compounds as antibacterials |
| WO2018051306A1 (en) | 2016-09-19 | 2018-03-22 | Novartis Ag | Therapeutic combinations comprising a raf inhibitor and a erk inhibitor |
| KR20230093341A (ko) | 2016-10-27 | 2023-06-27 | 풀모킨 인코포레이티드 | 폐고혈압을 치료하기 위한 병용 요법 |
| US20180162291A1 (en) * | 2016-12-12 | 2018-06-14 | Wipro Limited | System and method of dynamically adjusting field of view of an image capturing device |
| EP3589323B1 (en) | 2017-03-01 | 2024-04-03 | Janssen Sciences Ireland Unlimited Company | Combination therapy for the treatment of tuberculosis |
| KR20240032157A (ko) | 2017-05-02 | 2024-03-08 | 노파르티스 아게 | 병용 요법 |
| CA3080971A1 (en) | 2017-11-02 | 2019-05-09 | Calico Life Sciences Llc | Modulators of the integrated stress pathway |
| KR102625224B1 (ko) * | 2018-10-31 | 2024-01-15 | 주식회사 큐로젠 | 피라졸-온 유도체를 유효성분으로 포함하는 자가면역질환의 예방, 개선 또는 치료용 조성물 |
| BR112021018168B1 (pt) | 2019-03-21 | 2023-11-28 | Onxeo | Composição farmacêutica, combinação e kit compreendendo uma molécula dbait e um inibidor de quinase para o tratamento de câncer |
| MA55976A (fr) * | 2019-05-13 | 2022-03-23 | Novartis Ag | Formes cristallines de n-(5-(5-((1r, 2s)-2-fluorocyclopropyl)-1,2,4-oxadiazol-3-yl)-2-methylphenyl) imidazo [1,2-a] pyridine-3-carboxamide |
| MX2021013817A (es) | 2019-05-13 | 2021-12-14 | Novartis Ag | Nuevas formas cristalinas de n-(3-(2-(2-hidroxietoxi)-6-morfolinop iridin-4-il)-4-metilfenil)-2-(trifluorometil)isonicotinamida como inhibidores de raf para el tratamiento del cancer. |
| WO2021035788A1 (zh) | 2019-08-29 | 2021-03-04 | 中国科学院合肥物质科学研究院 | 吡唑衍生物及其用途 |
| MX2022003037A (es) | 2019-09-13 | 2022-04-07 | Janssen Sciences Ireland Unlimited Co | Compuestos antibacterianos. |
| CA3159348A1 (en) | 2019-11-08 | 2021-05-14 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods for the treatment of cancers that have acquired resistance to kinase inhibitors |
| CN115315421B (zh) | 2019-12-13 | 2024-12-03 | 日本新药株式会社 | 作为pdgf受体激酶抑制剂的化合物和组合物 |
| WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
| US11767319B2 (en) | 2020-07-15 | 2023-09-26 | Third Harmonic Bio, Inc. | Crystalline forms of a selective c-kit kinase inhibitor |
| US11744823B2 (en) | 2020-11-19 | 2023-09-05 | Third Harmonic Bio, Inc. | Pharmaceutical compositions of a selective c-kit kinase inhibitor and methods for making and using same |
| CN117396475A (zh) | 2021-03-16 | 2024-01-12 | 爱尔兰詹森科学公司 | 抗菌化合物 |
| MX2023010941A (es) | 2021-03-17 | 2023-11-28 | Janssen Sciences Ireland Unlimited Co | Compuestos antibacterianos. |
| BR112023018655A2 (pt) | 2021-03-17 | 2023-12-12 | Janssen Sciences Ireland Unlimited Co | Compostos antibacterianos |
| TW202325274A (zh) | 2021-10-28 | 2023-07-01 | 愛爾蘭商健生科學愛爾蘭無限公司 | 抗菌化合物 |
| WO2024089170A1 (en) | 2022-10-27 | 2024-05-02 | Janssen Sciences Ireland Unlimited Company | Antibacterial compounds |
| EP4626884A1 (en) * | 2022-11-30 | 2025-10-08 | Blueprint Medicines Corporation | N-phenyl-pyrazolo[1,5-a]pyridine-3-carboxamide derivatives as wild type c-kit kinase inhibitors for the treatment of urticaria |
| CN120677155A (zh) * | 2022-12-07 | 2025-09-19 | 第三谐波生物股份有限公司 | 作为c-Kit激酶抑制剂的化合物和组合物 |
| CN120659784A (zh) * | 2022-12-07 | 2025-09-16 | 第三谐波生物股份有限公司 | 作为c-Kit激酶抑制剂的化合物和组合物 |
| WO2024223859A1 (en) | 2023-04-26 | 2024-10-31 | Janssen Pharmaceutica Nv | Antibacterial compounds |
| WO2025072330A1 (en) * | 2023-09-26 | 2025-04-03 | Arcus Biosciences, Inc. | Kit inhibitor compounds and methods of use thereof |
| WO2025256552A1 (zh) * | 2024-06-11 | 2025-12-18 | 上海翰森生物医药科技有限公司 | 吡唑类衍生物抑制剂、其制备方法和应用 |
| WO2025256609A1 (en) * | 2024-06-13 | 2025-12-18 | Third Harmonic Bio, Inc. | Crystalline forms of a selective c-kit kinase inhibitor |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003251561A1 (en) | 2002-06-20 | 2004-01-06 | Beacon Looms, Inc. | Knitted electrical conductor fabric |
| CA2514733A1 (en) | 2003-02-28 | 2004-09-16 | Transform Pharmaceuticals, Inc. | Pharmaceutical co-crystal compositions of drugs such as carbamazepine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen |
| ES2390227T3 (es) | 2004-09-09 | 2012-11-07 | Natco Pharma Limited | Nuevos derivados de fenilaminopirimidina como inhibidores de la BCR-ABL kinasa |
| JP5197016B2 (ja) | 2004-12-23 | 2013-05-15 | デシファラ ファーマスーティカルズ， エルエルシー | 酵素モジュレータ及び治療 |
| US7754717B2 (en) * | 2005-08-15 | 2010-07-13 | Amgen Inc. | Bis-aryl amide compounds and methods of use |
| CA2668190A1 (en) * | 2006-11-03 | 2008-05-15 | Irm Llc | Compounds and compositions as protein kinase inhibitors |
| PE20140913A1 (es) * | 2010-11-15 | 2014-08-22 | Abbvie Inc | Inhibidores de nampt y rock |
| US20130023751A1 (en) | 2011-07-18 | 2013-01-24 | Samuel Victor Lichtenstein | Water retention monitoring |
| EP2751107A1 (en) | 2011-09-01 | 2014-07-09 | Irm Llc | Compounds and compositions as pdgfr kinase inhibitors |
| US9199981B2 (en) | 2011-09-01 | 2015-12-01 | Novartis Ag | Compounds and compositions as C-kit kinase inhibitors |
| JP6134319B2 (ja) | 2011-09-01 | 2017-05-24 | ノバルティス アーゲー | ｃ−ｋｉｔキナーゼインヒビターとしての化合物及び組成物 |
| US20150051206A1 (en) | 2011-09-01 | 2015-02-19 | Irm Llc | Compounds and compositions as c-kit kinase inhibitors |
-
2012
- 2012-08-29 JP JP2014528537A patent/JP6134319B2/ja active Active
- 2012-08-29 BR BR112014004560A patent/BR112014004560A2/pt not_active Application Discontinuation
- 2012-08-29 EP EP12756885.5A patent/EP2751104B1/en active Active
- 2012-08-29 ES ES12756885T patent/ES2761332T3/es active Active
- 2012-08-29 UY UY34301A patent/UY34301A/es not_active Application Discontinuation
- 2012-08-29 PH PH1/2014/500372A patent/PH12014500372A1/en unknown
- 2012-08-29 PE PE2014000295A patent/PE20140909A1/es not_active Application Discontinuation
- 2012-08-29 WO PCT/US2012/052802 patent/WO2013033167A1/en not_active Ceased
- 2012-08-29 CN CN201280042743.4A patent/CN103797011B/zh active Active
- 2012-08-29 MX MX2014002484A patent/MX339937B/es active IP Right Grant
- 2012-08-29 EA EA201490545A patent/EA026152B1/ru not_active IP Right Cessation
- 2012-08-29 US US13/598,213 patent/US8569283B2/en active Active
- 2012-08-29 PL PL12756885T patent/PL2751104T3/pl unknown
- 2012-08-29 KR KR1020147008107A patent/KR101962495B1/ko active Active
- 2012-08-29 SG SG2014014369A patent/SG2014014369A/en unknown
- 2012-08-29 CA CA2845169A patent/CA2845169C/en active Active
- 2012-08-29 PT PT127568855T patent/PT2751104T/pt unknown
- 2012-08-29 AU AU2012302042A patent/AU2012302042B2/en not_active Ceased
- 2012-08-29 AP AP2014007493A patent/AP2014007493A0/xx unknown
- 2012-08-31 AR ARP120103223 patent/AR087753A1/es unknown
- 2012-08-31 TW TW101131942A patent/TW201313717A/zh unknown
-
2013
- 2013-09-19 US US14/031,792 patent/US8754071B2/en active Active
-
2014
- 2014-02-17 ZA ZA2014/01175A patent/ZA201401175B/en unknown
- 2014-02-17 TN TNP2014000068A patent/TN2014000068A1/en unknown
- 2014-02-27 CL CL2014000492A patent/CL2014000492A1/es unknown
- 2014-02-27 GT GT201400034A patent/GT201400034A/es unknown
- 2014-02-27 IL IL231227A patent/IL231227A0/en unknown
- 2014-02-27 CU CU20140024A patent/CU20140024A7/es unknown
- 2014-02-28 CO CO14043417A patent/CO6900141A2/es unknown
- 2014-02-28 CR CR20140107A patent/CR20140107A/es unknown
- 2014-03-28 MA MA36864A patent/MA35460B1/fr unknown
- 2014-04-22 US US14/258,963 patent/US9023839B2/en active Active
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