JP2014520547A - A food production method that can reduce the time required for radioactive detoxification - Google Patents

Abstract

The present invention relates to a food production method that can be consumed in foods and can reduce the time required for radioactive detoxification that can reduce damage to the human body due to radiation exposure. The food production method that can be shortened includes: (a) obtaining a fine powder of each of propolis, seaweed, and useful plant; (b) extracting an active ingredient from said propolis, seaweed, and useful plant; (c) A step of mixing an active ingredient extracted from propolis, seaweed, and useful plant; in the step (b), the active ingredient of the propolis is a supercritical fluid extract of propolis, a water extract, an alcohol extract And a mixture selected from one or more of WEEP (Water Ethanol Extract Propolis) extract, , A mixture selected from one or more of a supercritical fluid extract, a water extract, and an alcohol extract of seaweed selected from the group consisting of Wakabu, Nori, Shikao, and Kabu, and an active ingredient of the useful plant Is a supercritical fluid extract of useful plants selected from the group consisting of chlorella, broccoli, bananas, green tea, plums, sorghum, aloe, concealed beans, roses, cocoons, peaches, apricots, oaks, persimmons, flat rice, water extraction It is characterized by being a mixture selected from at least one of a product and an alcohol extract.
[Selection] Figure 1

Description

  The present invention relates to a food production method that can be consumed with foods, and that can reduce the time required for radioactive detoxification that can reduce damage to the human body due to exposure to radiation.

  The use of radioactive materials is indispensable in modern civilization, but it is possible for humans to be exposed to radioactivity, such as exposure to radioactive workers and exposure to radiation from accidents, or treatment of radioactive waste Sex is increasing.

  Radiation exposure causes various damages, such as genetic mutations in animals and plants, and increased cancer incidence over the long term as well as damage to human lives. Therefore, efforts must be made to minimize damage to the human body due to radiation exposure.

  Conventionally, as one of the methods that can reduce the influence of radioactivity, there has been a method of eating seaweeds containing iodine and potassium components that are effective in discharging radioactivity components.

  However, the method of individually eating foods that contain iodine and potassium components is limited to immunity and detoxification to mild radioactivity, and some single component substances are impurities from radioactivity. There is a disadvantage that it is difficult to effectively achieve a detoxification function for certain cesium and iodine components.

  Further, the technology that is the background of the present invention is disclosed in Korean Published Patent Publication No. 10-2003-0087724 (November 15, 2003).

  In order to solve the above-mentioned problems, the present invention provides a food production that can reduce the time required for radioactive detoxification by extracting and fusing active ingredients with various extraction methods for substances effective for radioactive detoxification. Try to provide a way.

  In order to solve the above-described problems, the present invention provides a propolis extract; a seaweed extract; and a chlorella, broccoli, banana, green tea, plum, sorghum, aloe, concealed bean, rose, camellia, peach, apricot, and potato. And a useful plant extract selected from at least one selected from the group consisting of salmon and flat rice, and a food capable of reducing the time required for radioactive detoxification.

  Furthermore, the present invention comprises (a) obtaining a fine powder of each of propolis, seaweed and useful plant; (b) extracting an active ingredient from said propolis, seaweed and useful plant; (c) said propolis A step of mixing an active ingredient extracted from a seaweed and a useful plant, wherein in the step (b), the active ingredient of the propolis is a supercritical fluid extract of propolis, a water extract, an alcohol extract , And one or more selected from WEEP (Water Ethanol Extract Propolis) extract, wherein the active ingredient of the seaweed is one or more of supercritical fluid extract, water extract, and alcohol extract of seaweed The active ingredients of the useful plant are chlorella, broccoli, banana, green tea, plum, sorghum, aloe, concealment. It is a mixture selected from one or more of supercritical fluid extracts, water extracts, and alcohol extracts of useful plants selected from the group consisting of beans, roses, camellias, peaches, apricots, large persimmons, persimmons, and flat persimmons A food production method capable of shortening the time required for radioactive detoxification is provided.

  According to the present invention as described above, a propolis, seaweed, and useful plant active ingredients are extracted and mixed using a variety of extraction methods, thereby effectively reducing the time required for radioactive detoxification. Can be provided.

It is the form of the trial of the foodstuff manufacturing method which can shorten the radioactive detoxification time of this invention. This is a method for producing a propolis extract contained in a food product that can reduce the time required for radioactive detoxification.

  Hereinafter, the present invention will be described in detail with reference to the accompanying drawings and preferred embodiments.

  FIG. 1 is an embodiment of a food production method that can reduce the time required for radioactive detoxification according to the present invention, and FIG. 2 is a method for producing a propolis extract contained in food that can reduce the time required for radioactive detoxification. .

  The method for producing food that can reduce the time required for radioactive detoxification according to the present invention includes propolis extract; seaweed extract; and chlorella, broccoli, banana, green tea, plum, sorghum, aloe, herbaceous beans, rose, strawberry, peach, apricot, Useful plant extracts selected from at least one of large persimmon, persimmon and flat persimmon are used.

  The propolis is a substance made by mixing bee saliva and an enzyme with a substance such as a resin extracted by a bee from a plant, and has effects such as anti-flame, antioxidant, and immune enhancement, Water-soluble propolis is excellent in the effect of preventing radiation exposure.

  The propolis extract is a mixture selected from one or more of a supercritical fluid extract of propolis, a water extract, an alcohol extract, and a WEEP (Water Ethanol Extract Propolis) extract.

  At this time, various extracts of the propolis may be mixed and mixed at the same ratio.

  Prior to the extraction of the propolis extract, a net cage is covered on the nest box, and the raw material is collected from the bees, and then shaken off at a low temperature to ensure a solid state propolis. The propolis thus obtained is pulverized to a size of 3 mm or less, preferably 1 mm or less, and an extract is extracted from the pulverized propolis.

  The supercritical fluid extraction of the propolis can be performed with a supercritical fluid containing carbon dioxide.

  That is, while compressing by applying a strong pressure to the carbon dioxide extraction container, the propolis is converted from a solid to a liquid so as to be in a supercritical state, and after 2 to 3 hours have passed, the pressure is restored to the original state. To release the carbon dioxide pressure and extract the active ingredients.

  A supercritical fluid has a high density and a high dissolving power. When the pressure is released, the supercritical fluid has a low density and an excellent ability to separate an active substance from the fluid. Therefore, the extraction efficiency can be increased. Therefore, the obtained extract has a high content of flavonoids and polyphenols excellent in antioxidant action.

  The water extract of propolis is prepared by mixing propolis fine powder and water in a weight ratio of 1: 1 to 2, stirring at a temperature of 40 to 60 ° C. for 3 to 6 hours, and centrifuging the supernatant. It is a water extract obtained by filtering the liquid, dialyzing the filtrate with distilled water for 1 to 5 days and freeze-drying.

  At this time, the precipitate excluding the supernatant obtained by centrifugation is mixed and stirred with water at a weight ratio of 1: 1 to 3, and the secondary supernatant obtained by centrifuging the precipitate is mixed. In addition to the supernatant liquid obtained before the filtration, the filtrate is dialyzed with distilled water and freeze-dried to obtain a water extract.

  In the case of water extraction, the mineral content of propolis is high and the human body absorption rate is high.

  The alcohol extract of propolis is prepared by mixing propolis fine powder and alcohol in a weight ratio of 1: 2 to 4 and stirring the extract obtained by stirring at a temperature of 40 to 60 ° C. for 3 to 6 hours, It is an alcohol extract obtained by placing the filtered filtrate in an open container and flying the aldehyde component for 3 to 7 days.

  In this case, there is an advantage that a large amount of the fat-soluble component of propolis is extracted.

  As the alcohol, 80% ethanol can be used.

  In the present invention, the alcohol extract of propolis further comprises a micellar extract obtained by homogenizing in an emulsified state in which a fatty acid ester or an emulsifier of glycerin is mixed with the alcohol extract and extracting an active ingredient. To do.

  The emulsifier is uniformly dispersed so as to surround the fine particles of propolis fat and become familiar with water, and is added at a ratio of 10 to 20% by weight relative to the total weight.

  The WEP extract of propolis is prepared by mixing propolis fine powder in a mixed solution composed of 40% by weight of ethanol and 60% by weight of distilled water at a ratio of 10 to 30% by weight with respect to the total weight. It is a water-soluble extract obtained by filtering an extract obtained by stirring for 3 to 6 hours, and then placing the filtrate in an open container and removing the aldehyde component for 3 to 7 days.

  In this case, among the components of propolis, the active ingredient extracted only with water can be extracted by water solubilization without loss.

  One or more selected from the supercritical fluid extract, water extract, alcohol extract, and WEEP (Water Ethanol Extract Propolis) extract of propolis obtained as described above, and the radioactivity detoxification time of the present invention It is used in food manufacturing methods that can shorten In this case, the supercritical fluid extract, the water extract, the alcohol extract, and the WEEP (Water Ethanol Extract Propolis) extract can be added at the same ratio.

  In the present invention, the seaweed extract is a mixture selected from one or more of a seaweed supercritical fluid extract, a water extract, and an alcohol extract.

  Before extracting the seaweed extract, first, seaweeds such as kelp, young cloth, rice cloth, and laver are dried and pulverized with a drier to obtain seaweed fine powder.

  The supercritical fluid extraction, water extraction, and alcohol extraction of seaweed are the same as the supercritical fluid extraction, water extraction, and alcohol extraction processes of propolis.

  Since the supercritical fluid extract of seaweed has a high content of potassium and iodine, it is effective in shortening the time required for radioactivity detoxification.

  The seaweed water extract uses a water-soluble extract produced by mixing a water extract obtained through the same process as the propolis water extract with purified water at a ratio of 1: 1 to 3 be able to.

  One or more of the seaweed supercritical fluid extract, water extract, and alcohol extract obtained as described above are selected and mixed, and used in the food production method of the present invention that can reduce the time required for radioactivity detoxification. At this time, the supercritical fluid extract, the water extract, and the alcohol extract can be added at the same ratio.

  The useful plant extract is a useful plant selected from at least one of chlorella, broccoli, banana, green tea, plum, elephant kogyo, aloe, concealed beans, roses, grapes, peaches, apricots, large persimmons, persimmons, flat persimmons It is a mixture selected from one or more of a supercritical fluid extract, a water extract, and an alcohol extract.

  Prior to producing useful plant extracts, useful plants should be preceded by a process in which each material is dried and pulverized by a pulverizer.

  The supercritical fluid extraction, water extraction, and alcohol extraction of the useful plant are the same as the supercritical fluid extraction, water extraction, and alcohol extraction steps of propolis.

  The supercritical extract of useful plants has a high content of potassium and antioxidant components.

  The water extract of useful plants is a water-soluble extract produced by mixing a water extract obtained through a process similar to that of a seaweed water extract with purified water at a ratio of 1: 1 to 3. Can be used.

  One or more supercritical fluid extracts, water extracts, and alcohol extracts of useful plants obtained as described above are selected and mixed, and used in the food production method of the present invention that can reduce the time required for radioactive detoxification. At this time, the supercritical fluid extract, the water extract, and the alcohol extract can be added at the same ratio.

  The method for producing a food capable of shortening the time required for radioactive detoxification according to the present invention comprises (a) a step of obtaining fine powders of propolis, seaweeds and useful plants; (b) active ingredients from the propolis, seaweeds and useful plants. And (c) mixing the active ingredients extracted from the propolis, seaweeds and useful plants.

  The mixture produced through the above process is packaged in liquid, powder, granule, capsule or the like through a sterilization process.

  * In the step (b), the active ingredient of the propolis is a mixture selected from one or more of a propolis supercritical fluid extract, a water extract, an alcohol extract, and a WEEP (Water Ethanol Extract Propolis) extract. And the active ingredient of the seaweed is one or more selected from a supercritical fluid extract of seaweed selected from the group consisting of kelp, young cloth, seaweed, deer grass and silkworm, water extract and alcohol extract The active ingredient of the useful plant is selected from the group consisting of chlorella, broccoli, banana, green tea, plum, sorghum, aloe, hidden peas, rose, persimmon, peach, apricot, large persimmon, persimmon, flat persimmon It is a mixture selected from one or more of a supercritical fluid extract, a water extract, and an alcohol extract of a useful plant.

  The propolis, the seaweed, and the useful plant extract can be mixed in the same ratio, and the supercritical fluid extract, the water extract, the alcohol extract, and the WEEP (Water Ethanol Extract Propolis) extract of each material. Is produced through the process as described above.

  Hereinafter, the present invention will be described based on experimental examples.

[Experimental example]
Effect of food that can shorten the time required for radioactivity detoxification

1. Experimental plan After Sprague-Dawley male Rat (Samtaka Biocore, Korea) with a body weight of 80 to 110 g after 4 weeks of age was purchased and bred for 1 week, tissue cells were collected and used as experimental materials.

  The tissue cells are divided into control groups 1, 2, 3 and experimental groups in a test tube, and 0.05 cc of radioactive substances iodopotassium and cesium are administered to expose the animal tissue cells to the radioactive material. I let you. After that, the control group 1 has a useful plant extract to which the same percentages of the hidden beans, roses, camellias, bananas, peaches, apricots, large persimmons, persimmons, and flat persimmons of Table 1 are added. The seaweed extract to which young cloth, seaweed, deer grass and silk cloth were added at the same ratio, and the control group 3 were each administered the propolis stock solution, and the experimental group was fused with useful plants, seaweed and water-soluble propolis extract. 1 cc of each substance was administered to the control group and the experimental group for 9 days.

  At this time, the propolis, seaweed, and useful plant extract of the experimental group were added at a ratio of 1: 1: 1 propolis: seaweed: useful plant, and the propolis extract was a supercritical fluid extract of propolis, A water extract, an alcohol extract, and a WEEP (Water Ethanol Extract Propolis) extract were added at the same ratio, and a seaweed extract was extracted by adding kelp, young cloth, laver, deer grass, and koji cloth at the same ratio. Supercritical fluid extract, water extract, and alcohol extract are added in the same ratio, and useful plant extracts are added in the same ratio of hidden peas, rose, camellia, banana, peach, apricot, large persimmon, persimmon, and flat persimmon. A supercritical fluid extract, a water extract, and an alcohol extract extracted at the same ratio were used.

  The potassium and iodine contained in 100 g of propolis, seaweeds and useful plants are as shown in Table 1 below. In Table 1, “Component (100 g)” is the amount of potassium and iodine per 100 g for each of nine useful plants, or five seaweeds, or propolis, and “Average (100 g)” is nine useful plants. It is an average value of potassium and iodine per 100 g for a plant or five kinds of seaweeds.

2. Experimental Results Table 2 below shows experimental results for the present invention.

  As shown in Table 2, the results of measuring the period required for radioactivity detoxification, that is, the experimental group and the control group, were divided into a control group before fusing propolis, seaweed and useful plants and an experimental group after fusing. As a result of measuring the time taken from when cesium and iodine were not detected, it took 6 to 9 days to detoxify cesium and iodine before mixing propolis, seaweeds and useful plants. It can be seen that cesium took 3.2 days and iodine took 2.5 days.

  It was judged that the performance was maximized because the active ingredients contained in the material were extracted effectively and evenly with different extraction methods for propolis, seaweed and useful plants. The

  That is, the potassium component contained in the useful plants and seaweeds is to effectively discharge radioactive substances such as cesium and heavy metals, and the iodine contained in seaweeds is contained in radioactivity. This is to prevent inhalation. Furthermore, since propolis can suppress damage to radioactively contaminated cells, it is possible to develop a highly functional food capable of radioactive detoxification by fusing these three extracts.

Claims (6)

(A) obtaining fine powders of propolis, seaweed, and useful plants;
(B) a step of extracting an active ingredient from the propolis, seaweed, or useful plant;
(C) mixing the active ingredients extracted from the propolis, seaweed, and useful plants;
In the step (b),
The active ingredient of the propolis is a mixture selected from one or more of a supercritical fluid extract of propolis, a water extract, an alcohol extract, and a WEEP (Water Ethanol Extract Propolis) extract, and the active ingredient of the seaweed Is a mixture selected from one or more of a supercritical fluid extract, a water extract, and an alcohol extract of seaweed selected from the group consisting of kelp, young cloth, laver, deer grass, and koji. The active ingredient is a supercritical fluid extract of useful plants selected from the group consisting of chlorella, broccoli, bananas, green tea, plums, elephants, aloe, concealed beans, roses, cocoons, peaches, apricots, daikon, cocoons, and flat rice A food production method capable of shortening the time required for radioactive detoxification, which is a mixture selected from one or more of a water extract and an alcohol extract.   The method of claim 1, wherein the extraction of the supercritical fluid extract is performed with a supercritical fluid containing carbon dioxide.   The water extract is prepared by mixing fine powders of each material and water in a weight ratio of 1: 1 to 2 and stirring the mixture. After the supernatant obtained by centrifuging the mixture is filtered, the filtrate is distilled water. The food production method according to claim 1, which is a water extract obtained by dialysis and freeze-drying.   The alcohol extract was prepared by centrifuging an extract obtained by mixing and stirring fine powder of each material and alcohol at a weight ratio of 1: 2 to 4, and placing the filtered filtrate in an open container. It is an alcohol extract obtained by skipping an aldehyde component for a day, The food manufacturing method which can shorten the time required for radioactive detoxification of Claim 1 characterized by the above-mentioned.   The radioactive detoxification according to claim 4, wherein the alcohol extract of propolis further comprises a micellized extract obtained by extracting an active ingredient in an emulsified state in which a fatty acid ester or glycerin is mixed with the alcohol extract. A food manufacturing method that can shorten the time required.   The WEP extract of propolis is prepared by filtering an extract obtained by mixing and stirring a propolis fine powder in a mixed solution consisting of 40% by weight of ethanol and 60% by weight of distilled water, and then placing the filtrate in an open container. The water-soluble extract obtained by skipping an aldehyde component for 3 to 7 days;

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