JP2014519480A5 - - Google Patents

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Publication number
JP2014519480A5
JP2014519480A5 JP2014505330A JP2014505330A JP2014519480A5 JP 2014519480 A5 JP2014519480 A5 JP 2014519480A5 JP 2014505330 A JP2014505330 A JP 2014505330A JP 2014505330 A JP2014505330 A JP 2014505330A JP 2014519480 A5 JP2014519480 A5 JP 2014519480A5
Authority
JP
Japan
Prior art keywords
il1r1
cancer
il1racp
il1beta
csc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
JP2014505330A
Other languages
English (en)
Japanese (ja)
Other versions
JP2014519480A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2012/033490 external-priority patent/WO2012142391A1/en
Publication of JP2014519480A publication Critical patent/JP2014519480A/ja
Publication of JP2014519480A5 publication Critical patent/JP2014519480A5/ja
Abandoned legal-status Critical Current

Links

JP2014505330A 2011-04-15 2012-04-13 癌で使用される抗ｉｌ−１ｒ１阻害物質 Abandoned JP2014519480A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11003183.8 2011-04-15
EP11003183 2011-04-15
PCT/US2012/033490 WO2012142391A1 (en) 2011-04-15 2012-04-13 Anti- il-1r1 inhibitors for use in cancer

Publications (2)

Publication Number Publication Date
JP2014519480A JP2014519480A (ja) 2014-08-14
JP2014519480A5 true JP2014519480A5 (enExample) 2015-06-11

Family

ID=46018101

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014505330A Abandoned JP2014519480A (ja) 2011-04-15 2012-04-13 癌で使用される抗ｉｌ−１ｒ１阻害物質

Country Status (8)

Country Link
US (1) US20140308294A1 (enExample)
EP (1) EP2697260A1 (enExample)
JP (1) JP2014519480A (enExample)
CN (1) CN103492416A (enExample)
AU (1) AU2012242666A1 (enExample)
CA (1) CA2833147A1 (enExample)
IL (1) IL228847A0 (enExample)
WO (1) WO2012142391A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102046660A (zh) 2008-03-26 2011-05-04 塞勒兰特治疗公司 骨髓性血液学增殖性病症相关的免疫球蛋白和/或toll样受体蛋白及其用途
CN108026172B (zh) 2015-06-26 2022-04-29 赛诺菲生物技术公司 单克隆抗il-1racp抗体
CN107033216B (zh) * 2015-12-08 2021-08-03 财团法人农业科技研究院 靶向癌干细胞的胜肽和其应用
EP3241845A1 (en) * 2016-05-06 2017-11-08 MAB Discovery GmbH Humanized anti-il-1r3 antibodies
CN110431225B (zh) * 2017-03-10 2024-04-12 默克专利股份公司 受感染的细胞培养物
EP3401332A1 (en) * 2017-05-08 2018-11-14 MAB Discovery GmbH Anti-il-1r3 antibodies for use in inflammatory conditions
CA3066918A1 (en) 2017-06-12 2018-12-20 Bluefin Biomedicine, Inc. Anti-il1rap antibodies and antibody drug conjugates
IL279018B2 (en) * 2018-05-29 2026-02-01 Oncohost Ltd Cancer treatment by blocking host-induced interleukin-1 in combination with radiotherapy
TW202021618A (zh) 2018-08-17 2020-06-16 美商２３與我有限公司 抗ｉｌ１ｒａｐ抗體及其使用方法
CN109468380B (zh) * 2018-10-31 2022-05-17 复旦大学附属肿瘤医院 Il1r2在乳腺癌预后评估与靶向治疗中的应用
US20220233710A1 (en) * 2019-05-20 2022-07-28 Nantong Yichen Biopharma. Co. Ltd. Bispecific molecule and preparation and use thereof
EP4590704A1 (en) 2022-09-21 2025-07-30 Sanofi Biotechnology Humanized anti-il-1r3 antibody and methods of use

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU9803037D0 (en) 1988-05-27 1999-11-29 Synergen Inc Interleukin-1 inhibitors
US6472179B2 (en) 1998-09-25 2002-10-29 Regeneron Pharmaceuticals, Inc. Receptor based antagonists and methods of making and using
US6927044B2 (en) 1998-09-25 2005-08-09 Regeneron Pharmaceuticals, Inc. IL-1 receptor based cytokine traps
US20030007972A1 (en) * 1999-02-24 2003-01-09 Edward Tobinick Cytokine antagonists and other biologics for the treatment of bone metastases
WO2001042305A1 (en) 1999-12-10 2001-06-14 Amgen, Inc. Interleukin-1 receptor antagonist-like molecules and uses thereof
GB0020685D0 (en) 2000-08-22 2000-10-11 Novartis Ag Organic compounds
CN104178491B (zh) * 2002-09-06 2018-07-03 安姆根有限公司 治疗性人抗-il-1r1单克隆抗体
AR045614A1 (es) 2003-09-10 2005-11-02 Hoffmann La Roche Anticuerpos contra el recepctor de la interleuquina- 1 y los usos de los mismos
ES2569917T3 (es) 2005-06-21 2016-05-13 Xoma (Us) Llc Anticuerpos y fragmentos de los mismos que se unen a IL-1beta
US8298533B2 (en) 2008-11-07 2012-10-30 Medimmune Limited Antibodies to IL-1R1
WO2010089707A1 (en) * 2009-02-04 2010-08-12 Yeda Research And Development Co. Ltd. Methods and kits for determining sensitivity or resistance of prostate cancer to radiation therapy
GB2472856B (en) * 2009-08-21 2012-07-11 Cantargia Ab IL1-RAP modulators and uses thereof

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