JP2014514326A5 - - Google Patents

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Publication number
JP2014514326A5
JP2014514326A5 JP2014508181A JP2014508181A JP2014514326A5 JP 2014514326 A5 JP2014514326 A5 JP 2014514326A5 JP 2014508181 A JP2014508181 A JP 2014508181A JP 2014508181 A JP2014508181 A JP 2014508181A JP 2014514326 A5 JP2014514326 A5 JP 2014514326A5
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JP
Japan
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tic10
trail
composition
subject
cells
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JP2014508181A
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English (en)
Japanese (ja)
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JP2014514326A (ja
JP6132833B2 (ja
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Priority claimed from PCT/US2012/035831 external-priority patent/WO2012149546A2/en
Publication of JP2014514326A publication Critical patent/JP2014514326A/ja
Publication of JP2014514326A5 publication Critical patent/JP2014514326A5/ja
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JP2014508181A 2011-04-29 2012-04-30 抗癌療法としての正常細胞および腫瘍細胞の小分子ｔｒａｉｌ遺伝子誘導 Active JP6132833B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161480743P 2011-04-29 2011-04-29
US61/480,743 2011-04-29
PCT/US2012/035831 WO2012149546A2 (en) 2011-04-29 2012-04-30 Small molecule trail gene induction by normal and tumor cells as an anticancer therapy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016142086A Division JP2016199580A (ja) 2011-04-29 2016-07-20 抗癌療法としての正常細胞および腫瘍細胞の小分子ｔｒａｉｌ遺伝子誘導

Publications (3)

Publication Number Publication Date
JP2014514326A JP2014514326A (ja) 2014-06-19
JP2014514326A5 true JP2014514326A5 (https=) 2014-12-18
JP6132833B2 JP6132833B2 (ja) 2017-05-24

Family

ID=47068061

Family Applications (7)

Application Number Title Priority Date Filing Date
JP2014508181A Active JP6132833B2 (ja) 2011-04-29 2012-04-30 抗癌療法としての正常細胞および腫瘍細胞の小分子ｔｒａｉｌ遺伝子誘導
JP2016142086A Withdrawn JP2016199580A (ja) 2011-04-29 2016-07-20 抗癌療法としての正常細胞および腫瘍細胞の小分子ｔｒａｉｌ遺伝子誘導
JP2018210558A Withdrawn JP2019019145A (ja) 2011-04-29 2018-11-08 抗癌療法としての正常細胞および腫瘍細胞の小分子ｔｒａｉｌ遺伝子誘導
JP2021151110A Withdrawn JP2021185210A (ja) 2011-04-29 2021-09-16 抗癌療法としての正常細胞および腫瘍細胞の小分子ｔｒａｉｌ遺伝子誘導
JP2023033777A Active JP7600286B2 (ja) 2011-04-29 2023-03-06 抗癌療法としての正常細胞および腫瘍細胞の小分子ｔｒａｉｌ遺伝子誘導
JP2024027432A Pending JP2024051080A (ja) 2011-04-29 2024-02-27 抗癌療法としての正常細胞および腫瘍細胞の小分子ｔｒａｉｌ遺伝子誘導
JP2025133453A Pending JP2025159099A (ja) 2011-04-29 2025-08-08 抗癌療法としての正常細胞および腫瘍細胞の小分子ｔｒａｉｌ遺伝子誘導

Family Applications After (6)

Application Number Title Priority Date Filing Date
JP2016142086A Withdrawn JP2016199580A (ja) 2011-04-29 2016-07-20 抗癌療法としての正常細胞および腫瘍細胞の小分子ｔｒａｉｌ遺伝子誘導
JP2018210558A Withdrawn JP2019019145A (ja) 2011-04-29 2018-11-08 抗癌療法としての正常細胞および腫瘍細胞の小分子ｔｒａｉｌ遺伝子誘導
JP2021151110A Withdrawn JP2021185210A (ja) 2011-04-29 2021-09-16 抗癌療法としての正常細胞および腫瘍細胞の小分子ｔｒａｉｌ遺伝子誘導
JP2023033777A Active JP7600286B2 (ja) 2011-04-29 2023-03-06 抗癌療法としての正常細胞および腫瘍細胞の小分子ｔｒａｉｌ遺伝子誘導
JP2024027432A Pending JP2024051080A (ja) 2011-04-29 2024-02-27 抗癌療法としての正常細胞および腫瘍細胞の小分子ｔｒａｉｌ遺伝子誘導
JP2025133453A Pending JP2025159099A (ja) 2011-04-29 2025-08-08 抗癌療法としての正常細胞および腫瘍細胞の小分子ｔｒａｉｌ遺伝子誘導

Country Status (18)

Country Link
US (9) US8673923B2 (https=)
EP (4) EP3679934B1 (https=)
JP (7) JP6132833B2 (https=)
CA (1) CA2832342C (https=)
CY (1) CY1123010T1 (https=)
DK (3) DK3679934T3 (https=)
ES (3) ES2992934T3 (https=)
FI (2) FI4335511T3 (https=)
HR (3) HRP20200636T1 (https=)
HU (2) HUE049207T2 (https=)
LT (3) LT3679934T (https=)
MX (2) MX365365B (https=)
PL (3) PL2701708T3 (https=)
PT (3) PT4335511T (https=)
RS (3) RS65813B1 (https=)
SI (3) SI4335511T1 (https=)
SM (3) SMT202600075T1 (https=)
WO (1) WO2012149546A2 (https=)

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US10314594B2 (en) 2012-12-14 2019-06-11 Corquest Medical, Inc. Assembly and method for left atrial appendage occlusion
US10307167B2 (en) 2012-12-14 2019-06-04 Corquest Medical, Inc. Assembly and method for left atrial appendage occlusion
US10813630B2 (en) 2011-08-09 2020-10-27 Corquest Medical, Inc. Closure system for atrial wall
US20140142689A1 (en) 2012-11-21 2014-05-22 Didier De Canniere Device and method of treating heart valve malfunction
WO2015073072A1 (en) * 2013-11-15 2015-05-21 Oncoceutics, Inc. 7-benzyl-4-(2-methylbenzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1h)-one
US9376437B2 (en) 2013-03-13 2016-06-28 Oncoceutics, Inc 7-benzyl-4-(2-methylbenzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1H)-one, salts thereof and methods of using the same in combination therapy
US9688679B2 (en) 2013-03-13 2017-06-27 Oncoceutics, Inc. 7-benzyl-4-(methylbenzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-A]pyrido[3,4-E]pyrimidin-5 (1H)-one, salts thereof and methods of using the same in combination therapy
WO2014160130A1 (en) * 2013-03-13 2014-10-02 Oncoceutics, Inc. Combination therapy with 7-benzyl-10-(2-methylbenzyl)-2,6,7,8,9,10-hexahydroimidazo[1,2-a]pyrido[4,3-d]pyrimidin-5(3h)-one
IL311202A (en) 2013-11-15 2024-05-01 Oncoceutics Inc 7-Benzyl-4-(2-methylbenzyl)-2, 4, 6, 7, 8, 9-hexahydroimidazo [1,2-A] pyrido[3,4-E] pyrimidine-5(1H)one, its salts and methods Use
US9566443B2 (en) 2013-11-26 2017-02-14 Corquest Medical, Inc. System for treating heart valve malfunction including mitral regurgitation
US11299528B2 (en) 2014-03-11 2022-04-12 D&D Pharmatech Inc. Long acting TRAIL receptor agonists for treatment of autoimmune diseases
LT3662910T (lt) 2014-03-31 2024-12-27 The Scripps Research Institute Trail geno indukcijai skirtas farmakoforas
US10842626B2 (en) 2014-12-09 2020-11-24 Didier De Canniere Intracardiac device to correct mitral regurgitation
WO2016123571A1 (en) 2015-01-30 2016-08-04 Oncoceutics Inc. 7-benzyl-4-(2-methylbenzyl)-2,4,6,7,8,9-hexahydroimidazo [1,2-a]pyrido[3,4-e]pyrimidin-5(1h)-one, analogs and salts thereof and their use in therapy
JP2018510005A (ja) 2015-03-31 2018-04-12 ザ・ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル 幹細胞の送達媒体およびその使用
CN104860948B (zh) 2015-05-15 2017-09-26 南京盖特医药技术有限公司 咪唑并嘧啶酮类化合物及其制备方法和应用
WO2017106627A1 (en) 2015-12-17 2017-06-22 The Johns Hopkins University Ameliorating systemic sclerosis with death receptor agonists
PL3408298T3 (pl) 2016-01-29 2025-03-31 Oncoceutics, Inc. Modulacja przez imiprydony receptora sprzężonego z białkiem g (gpcr)
KR102508650B1 (ko) 2016-04-07 2023-03-13 더 존스 홉킨스 유니버시티 사멸 수용체 작용제로써 췌장암 및 통증을 치료하기 위한 조성물 및 방법
US10172862B2 (en) 2017-01-30 2019-01-08 Oncoceutics, Inc. Imipridones for gliomas
US11767353B2 (en) 2020-06-05 2023-09-26 Theraly Fibrosis, Inc. Trail compositions with reduced immunogenicity
WO2024030645A1 (en) 2022-08-05 2024-02-08 Chimerix, Inc. Pharmaceutical compositions and uses thereof for the treatment of glioma
WO2024102447A1 (en) * 2022-11-10 2024-05-16 Emory University Uses of hydroimidazopyridopyrimidinone derivatives for managing aneurysms or other vascular conditions or diseases

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WO2014160130A1 (en) 2013-03-13 2014-10-02 Oncoceutics, Inc. Combination therapy with 7-benzyl-10-(2-methylbenzyl)-2,6,7,8,9,10-hexahydroimidazo[1,2-a]pyrido[4,3-d]pyrimidin-5(3h)-one

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