JP2014511118A5 - - Google Patents
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- Publication number
- JP2014511118A5 JP2014511118A5 JP2013535151A JP2013535151A JP2014511118A5 JP 2014511118 A5 JP2014511118 A5 JP 2014511118A5 JP 2013535151 A JP2013535151 A JP 2013535151A JP 2013535151 A JP2013535151 A JP 2013535151A JP 2014511118 A5 JP2014511118 A5 JP 2014511118A5
- Authority
- JP
- Japan
- Prior art keywords
- gata
- cell
- cells
- megakaryocyte
- stem cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40651410P | 2010-10-25 | 2010-10-25 | |
| US61/406,514 | 2010-10-25 | ||
| PCT/US2011/057716 WO2012061146A1 (en) | 2010-10-25 | 2011-10-25 | Compositions and methods for the generation of platelets and methods of use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014511118A JP2014511118A (ja) | 2014-05-08 |
| JP2014511118A5 true JP2014511118A5 (enExample) | 2014-12-11 |
| JP6126004B2 JP6126004B2 (ja) | 2017-05-10 |
Family
ID=46024776
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013535151A Expired - Fee Related JP6126004B2 (ja) | 2010-10-25 | 2011-10-25 | 血小板の生成のための組成物および方法、およびそれらの使用の方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9259443B2 (enExample) |
| EP (1) | EP2633047A4 (enExample) |
| JP (1) | JP6126004B2 (enExample) |
| AU (1) | AU2011323729B2 (enExample) |
| CA (1) | CA2815426A1 (enExample) |
| WO (1) | WO2012061146A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201210857D0 (en) | 2012-06-19 | 2012-08-01 | Cambridge Entpr Ltd | Transcription factor mediated programming towards megakaryocytes |
| US9074186B2 (en) * | 2012-08-15 | 2015-07-07 | Boston Medical Center Corporation | Production of red blood cells and platelets from stem cells |
| EP3973967A1 (en) | 2012-12-21 | 2022-03-30 | Astellas Institute for Regenerative Medicine | Methods for production of platelets from pluripotent stem cells and compositions thereof |
| WO2014138485A1 (en) * | 2013-03-08 | 2014-09-12 | Irm Llc | Ex vivo production of platelets from hematopoietic stem cells and the product thereof |
| US11319528B2 (en) | 2015-07-13 | 2022-05-03 | University Of Utah Research Foundation | Methods of making red blood cells and platelets in vitro and uses thereof |
| WO2018053288A1 (en) * | 2016-09-16 | 2018-03-22 | The Children's Hospital Of Philadelphia | Methods and compositions for identification and enrichment of platelet-producing megakaryocytes (mks) |
| MX2020007071A (es) | 2018-01-05 | 2020-11-11 | Platelet Biogenesis Inc | Composiciones y metodos para producir megacariocitos. |
| WO2020006539A1 (en) | 2018-06-29 | 2020-01-02 | Platelet Biogenesis, Inc. | Compositions for drug delivery and methods of use thereof |
| AU2019354370A1 (en) * | 2018-10-05 | 2021-05-13 | University Of Utah Research Foundation | Methods of making platelets comprising modified receptors and uses thereof |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5824297A (en) | 1990-06-25 | 1998-10-20 | Oncogene Science, Inc. | Tissue-derived tumor growth inhibitors, methods of preparation and uses thereof |
| US5817662A (en) | 1992-11-09 | 1998-10-06 | Cell Therapeutics, Inc. | Substituted amino alkyl compounds |
| US5772992A (en) | 1992-11-24 | 1998-06-30 | G.D. Searle & Co. | Compositions for co-administration of interleukin-3 mutants and other cytokines and hematopoietic factors |
| US5571686A (en) | 1994-04-14 | 1996-11-05 | Massachusetts Institute Of Technology | Method of using megapoietin for prolonging the survival & viability of platlets |
| DE69635899T2 (de) | 1995-11-17 | 2006-11-23 | Asahi Kasei Kabushiki Kaisha | Polypeptid, das die differenzierung unterdrueckt |
| US5811297A (en) | 1996-03-07 | 1998-09-22 | Amba Biosciences, Llc | Immortalized hematopoietic cell lines, cell system thereof with stromal cells, in vitro, ex vivo and in vivo uses, & in vitro generation of dendritic cells and macrophages |
| US5753506A (en) | 1996-05-23 | 1998-05-19 | Cns Stem Cell Technology, Inc. | Isolation propagation and directed differentiation of stem cells from embryonic and adult central nervous system of mammals |
| US6291210B1 (en) | 1996-07-16 | 2001-09-18 | Asahi Kasei Kabushiki Kaisha | Differentiation inhibitor |
| US6066778A (en) | 1996-11-06 | 2000-05-23 | The Regents Of The University Of Michigan | Transgenic mice expressing APC resistant factor V |
| US6335195B1 (en) | 1997-01-28 | 2002-01-01 | Maret Corporation | Method for promoting hematopoietic and mesenchymal cell proliferation and differentiation |
| US6248587B1 (en) | 1997-11-26 | 2001-06-19 | University Of Southern Cailfornia | Method for promoting mesenchymal stem and lineage-specific cell proliferation |
| JPH11180877A (ja) | 1997-12-17 | 1999-07-06 | Asahi Chem Ind Co Ltd | 巨核球前駆細胞を含む細胞製剤及びその製造方法 |
| EP1090992A4 (en) | 1998-04-28 | 2004-05-19 | Ono Pharmaceutical Co | NEW POLYPEPTIDE, DNA CODING IT, AND ITS USE |
| EP1980617A1 (en) | 1998-12-31 | 2008-10-15 | Novartis Vaccines and Diagnostics, Inc. | Improved expression of HIV polypeptides and production of virus-like particles |
| US6586390B1 (en) | 2000-01-21 | 2003-07-01 | Hyseq, Inc. | Methods and materials relating to novel prothrombinase-like polypeptides and polynucleotides |
| US6465620B1 (en) | 2000-01-21 | 2002-10-15 | Hyseq, Inc. | Methods and materials relating to novel von Willebrand/Thrombospondin-like polypeptides and polynucleotides |
| US6569662B1 (en) | 2000-01-21 | 2003-05-27 | Hyseq, Inc. | Nucleic acids and polypeptides |
| US6673904B2 (en) | 2000-12-23 | 2004-01-06 | Kirin Beer Kabushiki Kaisha | Stem cell growth factor-like polypeptides |
| US20040192599A1 (en) | 2001-06-15 | 2004-09-30 | Schuh Andre C | Gene therapy for hemophilia a |
| CA2457694A1 (en) | 2001-08-09 | 2003-02-20 | Cornell Research Foundation, Inc. | Platelet-derived growth factor protection of cardiac myocardium |
| EP1336846A1 (en) | 2002-02-13 | 2003-08-20 | Procorde GmbH | Method for generating recombinant human platelets for identifying therapeutic target proteins |
| WO2003087333A2 (en) | 2002-04-12 | 2003-10-23 | Celgene Corporation | Modulation of stem and progenitor cell differentiation, assays, and uses thereof |
| AU2003231950A1 (en) | 2002-05-30 | 2003-12-19 | Celgene Corporation | Modulating cell differentiation and treating myeloproliferative disorders with JNK/MKK inhibitors |
| US7012005B2 (en) | 2002-06-25 | 2006-03-14 | Siliconix Incorporated | Self-aligned differential oxidation in trenches by ion implantation |
| WO2005103234A1 (en) | 2004-04-23 | 2005-11-03 | Héma-Québec | A new method of expanding cord blood cells |
| CN105168250B (zh) | 2004-10-25 | 2019-02-05 | 塞勒兰特治疗公司 | 增殖骨髓细胞群体的方法及其应用 |
| WO2006050330A2 (en) | 2004-11-01 | 2006-05-11 | Wisconsin Alumni Research Foundation | Platelets from stem cells |
| US20070077654A1 (en) | 2004-11-01 | 2007-04-05 | Thomson James A | Platelets from stem cells |
| JPWO2007049749A1 (ja) | 2005-10-28 | 2009-04-30 | ディナベック株式会社 | 血液凝固異常の治療方法 |
| US20080275049A1 (en) | 2007-05-04 | 2008-11-06 | Reddy Us Therapeutics, Inc. | Methods and Compositions for Upregulation of GATA Activity |
| WO2008151386A1 (en) * | 2007-06-15 | 2008-12-18 | Australian Stem Cell Centre Ltd | Megakaryocyte differentiation |
| EP2315829B1 (en) | 2008-08-08 | 2015-02-11 | Mayo Foundation For Medical Education And Research | Induced pluripotent stem cells |
| CN102712904A (zh) | 2009-11-11 | 2012-10-03 | 桑福德—伯恩哈姆医学研究协会 | 用于产生和调节iPS细胞的方法及其组合物 |
-
2011
- 2011-10-25 WO PCT/US2011/057716 patent/WO2012061146A1/en not_active Ceased
- 2011-10-25 JP JP2013535151A patent/JP6126004B2/ja not_active Expired - Fee Related
- 2011-10-25 US US13/881,587 patent/US9259443B2/en active Active
- 2011-10-25 EP EP11838540.0A patent/EP2633047A4/en not_active Withdrawn
- 2011-10-25 AU AU2011323729A patent/AU2011323729B2/en not_active Ceased
- 2011-10-25 CA CA2815426A patent/CA2815426A1/en not_active Abandoned
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