JP2014509656A5 - - Google Patents
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- Publication number
- JP2014509656A5 JP2014509656A5 JP2014502855A JP2014502855A JP2014509656A5 JP 2014509656 A5 JP2014509656 A5 JP 2014509656A5 JP 2014502855 A JP2014502855 A JP 2014502855A JP 2014502855 A JP2014502855 A JP 2014502855A JP 2014509656 A5 JP2014509656 A5 JP 2014509656A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- subject
- proanthocyanidins
- weight
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229920002770 condensed tannin Polymers 0.000 claims description 15
- 239000008194 pharmaceutical composition Substances 0.000 claims description 14
- 210000001035 gastrointestinal tract Anatomy 0.000 claims description 9
- 208000027866 inflammatory disease Diseases 0.000 claims description 8
- 241000894006 Bacteria Species 0.000 claims description 6
- 244000052616 bacterial pathogen Species 0.000 claims description 6
- 208000035143 Bacterial infection Diseases 0.000 claims description 5
- 208000036142 Viral infection Diseases 0.000 claims description 5
- 230000001580 bacterial effect Effects 0.000 claims description 5
- 208000022362 bacterial infectious disease Diseases 0.000 claims description 5
- HVQAJTFOCKOKIN-UHFFFAOYSA-N flavonol Natural products O1C2=CC=CC=C2C(=O)C(O)=C1C1=CC=CC=C1 HVQAJTFOCKOKIN-UHFFFAOYSA-N 0.000 claims description 5
- 235000011957 flavonols Nutrition 0.000 claims description 5
- 230000009385 viral infection Effects 0.000 claims description 5
- 230000002496 gastric effect Effects 0.000 claims description 4
- 206010009900 Colitis ulcerative Diseases 0.000 claims description 3
- 208000011231 Crohn disease Diseases 0.000 claims description 3
- 208000022559 Inflammatory bowel disease Diseases 0.000 claims description 3
- 201000006704 Ulcerative Colitis Diseases 0.000 claims description 3
- 239000002260 anti-inflammatory agent Substances 0.000 claims description 3
- 206010009887 colitis Diseases 0.000 claims description 3
- 208000008609 collagenous colitis Diseases 0.000 claims description 3
- 230000007423 decrease Effects 0.000 claims description 3
- 150000002216 flavonol derivatives Chemical class 0.000 claims description 3
- 208000002551 irritable bowel syndrome Diseases 0.000 claims description 3
- 208000008275 microscopic colitis Diseases 0.000 claims description 3
- 241000124008 Mammalia Species 0.000 claims description 2
- 239000003242 anti bacterial agent Substances 0.000 claims description 2
- JPFCOVZKLAXXOE-XBNSMERZSA-N (3r)-2-(3,5-dihydroxy-4-methoxyphenyl)-8-[(2r,3r,4r)-3,5,7-trihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2h-chromen-4-yl]-3,4-dihydro-2h-chromene-3,5,7-triol Chemical compound C1=C(O)C(OC)=C(O)C=C1C1[C@H](O)CC(C(O)=CC(O)=C2[C@H]3C4=C(O)C=C(O)C=C4O[C@@H]([C@@H]3O)C=3C=CC(O)=CC=3)=C2O1 JPFCOVZKLAXXOE-XBNSMERZSA-N 0.000 claims 1
- 229920001991 Proanthocyanidin Polymers 0.000 claims 1
- 229940124599 anti-inflammatory drug Drugs 0.000 claims 1
- 229940088710 antibiotic agent Drugs 0.000 claims 1
- 239000000203 mixture Substances 0.000 description 19
- 238000000034 method Methods 0.000 description 13
- 208000024891 symptom Diseases 0.000 description 3
- 229940121363 anti-inflammatory agent Drugs 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 208000035475 disorder Diseases 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 150000007946 flavonol Chemical class 0.000 description 2
- 230000000737 periodic effect Effects 0.000 description 2
- 206010061218 Inflammation Diseases 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161471073P | 2011-04-01 | 2011-04-01 | |
| US61/471,073 | 2011-04-01 | ||
| PCT/US2012/031581 WO2012135702A1 (en) | 2011-04-01 | 2012-03-30 | Inflammation and immunity treatments |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014509656A JP2014509656A (ja) | 2014-04-21 |
| JP2014509656A5 true JP2014509656A5 (https=) | 2015-04-23 |
Family
ID=46931951
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014502855A Pending JP2014509656A (ja) | 2011-04-01 | 2012-03-30 | 炎症および免疫の治療 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US9895341B2 (https=) |
| JP (1) | JP2014509656A (https=) |
| CA (1) | CA2832059C (https=) |
| WO (1) | WO2012135702A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20130476A1 (it) * | 2013-03-28 | 2014-09-29 | Novintethical Pharma Sagl | Composizioni per il trattamento di disturbi gastro-intestinali a base di complessi di tannini con proteine |
| US10034704B2 (en) | 2015-06-30 | 2018-07-31 | Ethicon Llc | Surgical instrument with user adaptable algorithms |
| JOP20190276B1 (ar) * | 2017-05-31 | 2024-04-18 | Napo Pharmaceuticals Inc | طرق وتركيبات لعلاج إسهال الحمض الصفراوي، والإسهال المرتبط باستئصال الأمعاء الدقيقة أو إزالة المرارة، ومتلازمة الأمعاء القصيرة |
| BE1029502B1 (fr) * | 2021-08-19 | 2023-01-17 | The Akkermansia Company | Composition comprenant de l'Akkermansia muciniphila pasteurisée pour le traitement ou la prévention de l'anxiété liée au syndrome du côlon irritable |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0935417B1 (en) | 1996-10-16 | 2009-05-06 | Napo Pharmaceuticals, Inc. | Enteric formulations of proanthocyanidin polymer antidiarrheal compositions |
| JP2975997B2 (ja) * | 1998-03-04 | 1999-11-10 | 工業技術院長 | プロアントシアニジンａおよびその誘導体 |
| US20020054924A1 (en) * | 2000-04-13 | 2002-05-09 | Leahy Margaret M. | Novel compositions derived from cranberry and grapefruit and therapeutic uses therefor |
| US7306815B2 (en) | 2000-08-31 | 2007-12-11 | Phenolics, Llc | Compositions enriched in phenolic compounds and methods for producing the same |
| EP1676572A1 (en) | 2003-09-26 | 2006-07-05 | Kirin Beer Kabushiki Kaisha | Remedy for autoimmune diseases |
| JP5167461B2 (ja) * | 2005-09-16 | 2013-03-21 | 国立医薬品食品衛生研究所長 | 炎症性腸疾患予防剤 |
| US20070254050A1 (en) | 2006-05-01 | 2007-11-01 | Quart Barry D | Method for treatment of diarrhea-predominant irritable bowel syndrome |
| WO2008004224A2 (en) * | 2006-07-03 | 2008-01-10 | Arie Levine | Synergistic compositions for crohn's disease and inflammatory gastrointestinal disorders |
| US20090226548A1 (en) * | 2008-01-11 | 2009-09-10 | U.S. Nutraceuticals, Llc D/B/A Valensa International | Method of preventing, controlling and ameliorating urinary tract infections using a synergistic cranberry derivative and d-mannose composition |
| JP5462491B2 (ja) * | 2009-01-21 | 2014-04-02 | 株式会社 エフェクト | プロアントシアニジン三量体 |
| PL2792254T3 (pl) * | 2009-04-16 | 2017-06-30 | Ocean Spray Cranberries, Inc. | Ekstrakcja związków fenolowych i ich zastosowanie w kompozycjach z kwasem fumarowym |
| WO2011088420A1 (en) * | 2010-01-15 | 2011-07-21 | Ocean Spray Cranberries, Inc. | Process for extracting compound from cranberry leaves and related products |
| US9314494B2 (en) * | 2012-05-25 | 2016-04-19 | The United States Of America, As Represented By The Secretary Of Agriculture | Cranberry xyloglucan oligosaccharide composition |
-
2012
- 2012-03-30 WO PCT/US2012/031581 patent/WO2012135702A1/en not_active Ceased
- 2012-03-30 JP JP2014502855A patent/JP2014509656A/ja active Pending
- 2012-03-30 US US14/008,995 patent/US9895341B2/en active Active
- 2012-03-30 CA CA2832059A patent/CA2832059C/en active Active
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