JP2014505015A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2014505015A5 JP2014505015A5 JP2013537131A JP2013537131A JP2014505015A5 JP 2014505015 A5 JP2014505015 A5 JP 2014505015A5 JP 2013537131 A JP2013537131 A JP 2013537131A JP 2013537131 A JP2013537131 A JP 2013537131A JP 2014505015 A5 JP2014505015 A5 JP 2014505015A5
- Authority
- JP
- Japan
- Prior art keywords
- interferon
- therapeutic agent
- additional therapeutic
- teriflunomide
- fingolimod
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 claims 2
- 229940124597 therapeutic agent Drugs 0.000 claims 2
- YLOCGHYTXIINAI-XKUOMLDTSA-N (2s)-2-amino-3-(4-hydroxyphenyl)propanoic acid;(2s)-2-aminopentanedioic acid;(2s)-2-aminopropanoic acid;(2s)-2,6-diaminohexanoic acid Chemical compound C[C@H](N)C(O)=O.NCCCC[C@H](N)C(O)=O.OC(=O)[C@@H](N)CCC(O)=O.OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 YLOCGHYTXIINAI-XKUOMLDTSA-N 0.000 claims 1
- PTOAARAWEBMLNO-KVQBGUIXSA-N Cladribine Chemical compound C1=NC=2C(N)=NC(Cl)=NC=2N1[C@H]1C[C@H](O)[C@@H](CO)O1 PTOAARAWEBMLNO-KVQBGUIXSA-N 0.000 claims 1
- 108010072051 Glatiramer Acetate Proteins 0.000 claims 1
- 229940121710 HMGCoA reductase inhibitor Drugs 0.000 claims 1
- 108010005716 Interferon beta-1a Proteins 0.000 claims 1
- 108010050904 Interferons Proteins 0.000 claims 1
- 102000014150 Interferons Human genes 0.000 claims 1
- 229930003827 cannabinoid Natural products 0.000 claims 1
- 239000003557 cannabinoid Substances 0.000 claims 1
- 229960002436 cladribine Drugs 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 229960000556 fingolimod Drugs 0.000 claims 1
- KKGQTZUTZRNORY-UHFFFAOYSA-N fingolimod Chemical compound CCCCCCCCC1=CC=C(CCC(N)(CO)CO)C=C1 KKGQTZUTZRNORY-UHFFFAOYSA-N 0.000 claims 1
- 229940042385 glatiramer Drugs 0.000 claims 1
- 239000003862 glucocorticoid Substances 0.000 claims 1
- 239000002471 hydroxymethylglutaryl coenzyme A reductase inhibitor Substances 0.000 claims 1
- 229940079322 interferon Drugs 0.000 claims 1
- 229960004461 interferon beta-1a Drugs 0.000 claims 1
- KKZJGLLVHKMTCM-UHFFFAOYSA-N mitoxantrone Chemical compound O=C1C2=C(O)C=CC(O)=C2C(=O)C2=C1C(NCCNCCO)=CC=C2NCCNCCO KKZJGLLVHKMTCM-UHFFFAOYSA-N 0.000 claims 1
- 229960001156 mitoxantrone Drugs 0.000 claims 1
- 229960005027 natalizumab Drugs 0.000 claims 1
- 229940037128 systemic glucocorticoids Drugs 0.000 claims 1
- 229960000331 teriflunomide Drugs 0.000 claims 1
- UTNUDOFZCWSZMS-YFHOEESVSA-N teriflunomide Chemical compound C\C(O)=C(/C#N)C(=O)NC1=CC=C(C(F)(F)F)C=C1 UTNUDOFZCWSZMS-YFHOEESVSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1018519.7A GB2485169A (en) | 2010-11-03 | 2010-11-03 | (R)-flurbiprofen for use in the treatment of multiple sclerosis |
| GB1018519.7 | 2010-11-03 | ||
| PCT/EP2011/069319 WO2012059541A1 (en) | 2010-11-03 | 2011-11-03 | Novel treatment of multiple sclerosis (ms) |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014505015A JP2014505015A (ja) | 2014-02-27 |
| JP2014505015A5 true JP2014505015A5 (enExample) | 2014-10-23 |
| JP5903438B2 JP5903438B2 (ja) | 2016-04-13 |
Family
ID=43401688
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013537131A Expired - Fee Related JP5903438B2 (ja) | 2010-11-03 | 2011-11-03 | 多発性硬化症（ｍｓ）の新規の治療 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20130309199A1 (enExample) |
| EP (1) | EP2635271A1 (enExample) |
| JP (1) | JP5903438B2 (enExample) |
| KR (1) | KR101877587B1 (enExample) |
| CN (1) | CN103209692A (enExample) |
| BR (1) | BR112013010883A2 (enExample) |
| CA (1) | CA2816911C (enExample) |
| GB (1) | GB2485169A (enExample) |
| RU (1) | RU2595861C2 (enExample) |
| WO (1) | WO2012059541A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017080989A1 (en) | 2015-11-09 | 2017-05-18 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | (r)-fluriprofen for the prevention and/or treatment of diabetes |
| US12097292B2 (en) | 2016-08-28 | 2024-09-24 | Mapi Pharma Ltd. | Process for preparing microparticles containing glatiramer acetate |
| CN109982712A (zh) | 2016-08-31 | 2019-07-05 | Mapi医药公司 | 包含醋酸格拉替雷的储库系统 |
| BR112019017724A2 (pt) | 2017-03-26 | 2020-03-31 | Mapi Pharma Ltd. | Sistemas depot de glatiramer para tratar formas progressivas de esclerose múltipla |
| EP3709986B1 (en) | 2017-11-14 | 2023-11-01 | Merck Sharp & Dohme LLC | Novel substituted biaryl compounds as indoleamine 2,3-dioxygenase (ido) inhibitors |
| BR112020008258B8 (pt) | 2017-11-14 | 2023-01-31 | Merck Sharp & Dohme | Compostos de biarila substituída ou seus sais farmaceuticamente aceitáveis, sua composição e seu uso como inibidores de indoleamina 2,3-dioxigenase (ido) |
| EA035792B1 (ru) * | 2018-06-21 | 2020-08-11 | Государственное Научное Учреждение "Институт Биоорганической Химии Национальной Академии Наук Беларуси" | Лекарственное средство пролонгированного действия для лечения рассеянного склероза (варианты) |
| CN113880899B (zh) * | 2020-10-30 | 2023-06-23 | 杭州拉林智能科技有限公司 | 黄酮苷-有机胺类神经激动剂复盐化合物及其制备方法和应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19907895A1 (de) * | 1999-02-24 | 2000-11-16 | Paz Arzneimittelentwicklung | Verwendung von R-Arylpropionsäuren zur Herstellung von Arzneimitteln zur Behandlung von Erkrankungen bei Mensch und Tier, welche durch die Hemmung der Aktivierung von NF-kB therapeutisch beeinflußt werden können |
| JP2006517925A (ja) * | 2003-01-14 | 2006-08-03 | メルク エンド カムパニー インコーポレーテッド | Ａβ４２低下薬としてのジェミナル二置換ＮＳＡＩＤ誘導体 |
| WO2008036733A2 (en) * | 2006-09-19 | 2008-03-27 | Myriad Genetics, Inc. | Methods for treatment of vesicle transport disorders |
| WO2008034244A1 (en) * | 2006-09-21 | 2008-03-27 | Waratah Pharmaceuticals Inc. | The combination of a cyclohexanehexol and a nsaid for the treatment of neurodegenerative diseases |
| CA2710318A1 (en) * | 2007-12-21 | 2009-07-09 | Paz Arzneimittel-Entwicklungsgesellscaft Mbh | Drugs as well as their production and use in the treatment of pain-associated neuropathies |
| US20090162421A1 (en) * | 2007-12-21 | 2009-06-25 | Paz Arzneimittel-Entwicklungsgesellschaft Mbh | Drugs as well as their production and use in the treatment of pain-associated neuropathies |
| KR20130079353A (ko) * | 2010-04-21 | 2013-07-10 | 키에시 파르마슈티시 엣스. 피. 에이. | 트랜스티레틴 아밀로이드증 치료용 1-(2-플루오로비페닐-4-일)-알킬 카복실산 유도체 |
-
2010
- 2010-11-03 GB GB1018519.7A patent/GB2485169A/en not_active Withdrawn
-
2011
- 2011-11-03 BR BR112013010883A patent/BR112013010883A2/pt not_active Application Discontinuation
- 2011-11-03 CA CA2816911A patent/CA2816911C/en not_active Expired - Fee Related
- 2011-11-03 JP JP2013537131A patent/JP5903438B2/ja not_active Expired - Fee Related
- 2011-11-03 RU RU2013125470/15A patent/RU2595861C2/ru active
- 2011-11-03 EP EP11784967.9A patent/EP2635271A1/en not_active Withdrawn
- 2011-11-03 WO PCT/EP2011/069319 patent/WO2012059541A1/en not_active Ceased
- 2011-11-03 CN CN2011800529378A patent/CN103209692A/zh active Pending
- 2011-11-03 US US13/881,088 patent/US20130309199A1/en not_active Abandoned
- 2011-11-03 KR KR1020137010891A patent/KR101877587B1/ko not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1125421T1 (el) | Ριβονουκλεϊκα οξεα που περιεχουν ν1-μεθυλο- ψευδοουρακιλες και χρησεις αυτων | |
| HRP20192202T1 (hr) | Acc inhibitori i njihove upotrebe | |
| EA201070182A1 (ru) | Алкилсульфонилзамещённые тиазолидные соединения | |
| PH12016500486A1 (en) | Aza-pyridone compounds and uses thereof | |
| CR20130409A (es) | Novedosos derivados de azabencimidazolcíclico útiles como agentes antidiabéticos | |
| WO2011106322A3 (en) | Biomarkers for acute ischemic stroke | |
| HUE056636T2 (hu) | Cisz-1,1,1,4,4,4-hexafluor-2-butén azeotróp-jellegû készítményei | |
| WO2011150190A3 (en) | Hcv inhibitor compounds and methods of use thereof | |
| MX370085B (es) | Compuestos de piridazinona y usos de los mismos. | |
| EA201071378A1 (ru) | Дронедарон для предотвращения постоянной фибрилляции предсердий | |
| GEP20186885B (en) | Novel compounds | |
| WO2011113060A3 (en) | Antiviral compounds and methods of use thereof | |
| JP2011519825A5 (enExample) | ||
| MX349802B (es) | Uso de aril- y hetarilcarboxamidas como endoparasiticidas. | |
| HK1198358A1 (en) | Sustained release composition of prostacyclin | |
| IN2014CN00572A (enExample) | ||
| MX350793B (es) | Pirroldicarboxamidas condensadas y su uso como agentes farmaceuticos. | |
| BR112014008555A2 (pt) | r(+)-n-formil-propargil-aminoindano | |
| CY1121696T1 (el) | Φαρμακευτικη συνθεση παρατεταμενης απελευθερωσης της τριμεταζιδινης | |
| ECSP14027694A (es) | Composiciones y métodos de polipéptidos-complejo de quelato de oligonucleótido | |
| UA107592C2 (uk) | Композиція для боротьби з захворюваннями рослин і її застосування | |
| WO2016191363A8 (en) | Combination hiv therapeutic | |
| EP2738158A4 (en) | METAL-SALEN COMPLEX CONNECTION, LOCAL ANESTHETICS AND MEDIUM AGAINST MALIGNANT TUMORS | |
| EA201290954A1 (ru) | Композиция для топического применения | |
| UA113806C2 (xx) | Пероральний препарат для лікування серцево-судинних захворювань |