JP2014501750A5 - - Google Patents
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- Publication number
- JP2014501750A5 JP2014501750A5 JP2013545415A JP2013545415A JP2014501750A5 JP 2014501750 A5 JP2014501750 A5 JP 2014501750A5 JP 2013545415 A JP2013545415 A JP 2013545415A JP 2013545415 A JP2013545415 A JP 2013545415A JP 2014501750 A5 JP2014501750 A5 JP 2014501750A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- compound
- group
- formula
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 42
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 23
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 19
- 125000003118 aryl group Chemical group 0.000 claims 11
- 108090000765 processed proteins & peptides Proteins 0.000 claims 10
- 125000005843 halogen group Chemical group 0.000 claims 8
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 claims 6
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 claims 6
- 125000000217 alkyl group Chemical group 0.000 claims 6
- 239000000203 mixture Substances 0.000 claims 6
- 125000000896 monocarboxylic acid group Chemical group 0.000 claims 6
- 125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 claims 5
- 125000000592 heterocycloalkyl group Chemical group 0.000 claims 5
- 150000001413 amino acids Chemical class 0.000 claims 4
- -1 cyclic acetal Chemical class 0.000 claims 4
- 239000012620 biological material Substances 0.000 claims 3
- 239000002537 cosmetic Substances 0.000 claims 3
- 229910052731 fluorine Chemical group 0.000 claims 3
- 125000001153 fluoro group Chemical group F* 0.000 claims 3
- 125000001072 heteroaryl group Chemical group 0.000 claims 3
- 102000004196 processed proteins & peptides Human genes 0.000 claims 3
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 claims 2
- AYFVYJQAPQTCCC-GBXIJSLDSA-N L-threonine Chemical compound C[C@@H](O)[C@H](N)C(O)=O AYFVYJQAPQTCCC-GBXIJSLDSA-N 0.000 claims 2
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 claims 2
- AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 claims 2
- 239000004473 Threonine Substances 0.000 claims 2
- DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 claims 2
- 239000000427 antigen Substances 0.000 claims 2
- 102000036639 antigens Human genes 0.000 claims 2
- 108091007433 antigens Proteins 0.000 claims 2
- 229940022399 cancer vaccine Drugs 0.000 claims 2
- 238000009566 cancer vaccine Methods 0.000 claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- 125000000524 functional group Chemical group 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 208000035143 Bacterial infection Diseases 0.000 claims 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 230000003712 anti-aging effect Effects 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 150000001720 carbohydrates Chemical class 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 150000004676 glycans Polymers 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 208000027866 inflammatory disease Diseases 0.000 claims 1
- 239000011159 matrix material Substances 0.000 claims 1
- 230000003278 mimic effect Effects 0.000 claims 1
- 230000003287 optical effect Effects 0.000 claims 1
- 210000000056 organ Anatomy 0.000 claims 1
- 150000004804 polysaccharides Polymers 0.000 claims 1
- 238000004321 preservation Methods 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
- 125000006239 protecting group Chemical group 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 150000003254 radicals Chemical class 0.000 claims 1
- 239000002994 raw material Substances 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 238000003786 synthesis reaction Methods 0.000 claims 1
- 230000003612 virological effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10306493.7 | 2010-12-22 | ||
| EP10306493 | 2010-12-22 | ||
| PCT/EP2011/073822 WO2012085221A1 (en) | 2010-12-22 | 2011-12-22 | Derivatives of glyco-cf2-serine and glyco-cf2-threonine |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014501750A JP2014501750A (ja) | 2014-01-23 |
| JP2014501750A5 true JP2014501750A5 (enExample) | 2015-02-19 |
| JP5934246B2 JP5934246B2 (ja) | 2016-06-15 |
Family
ID=43640126
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013545415A Expired - Fee Related JP5934246B2 (ja) | 2010-12-22 | 2011-12-22 | グリコ−ｃｆ２−セリンおよびグリコ−ｃｆ２−トレオニンの誘導体 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9175044B2 (enExample) |
| EP (1) | EP2655353B9 (enExample) |
| JP (1) | JP5934246B2 (enExample) |
| CN (1) | CN103328460B (enExample) |
| BR (1) | BR112013015869A2 (enExample) |
| CA (1) | CA2822097C (enExample) |
| MX (1) | MX2013007292A (enExample) |
| NZ (1) | NZ613333A (enExample) |
| RU (1) | RU2013133788A (enExample) |
| WO (1) | WO2012085221A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2943497A4 (en) | 2013-01-14 | 2017-05-03 | Advanomics Corp. | Gem-difluorinated c-glycoside compounds as anti-cancer agents |
| WO2015140178A1 (en) * | 2014-03-17 | 2015-09-24 | Tfchem | Glycopeptide derivatives for the preservation and protection of biological materials and microorganisms |
| JP2024504135A (ja) * | 2021-01-20 | 2024-01-30 | テーエフケム | 環状糖アミノ酸誘導体 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2842810B1 (fr) * | 2002-07-25 | 2006-01-27 | Inst Nat Sciences Appliq | Nouveaux composes gem difluores, leur procedes de preparation et leurs applications. |
| GB0224799D0 (en) * | 2002-10-25 | 2002-12-04 | Amersham Plc | Improved complex compositions |
| FR2878851B1 (fr) | 2004-12-02 | 2007-02-09 | Inst Nat Sciences Appliq | Composes c-glycopeptides gem-difluores, leur preparation et leur utilisation en cryochirurgie et/ou cryopreservation |
| FR2900154B1 (fr) | 2006-04-25 | 2008-07-04 | Inst Nat Sciences Appliq | Nouveaux composes c-glycosides gem-difluores derives de la podophyllotoxine, leur preparation et leurs applications. |
| FR2900656A1 (fr) | 2006-05-03 | 2007-11-09 | Inst Nat Sciences Appliq | Composes c-glycopeptides gem-difluores, leur preparation et leur utilisation notamment pour la preservation de materiaux biologiques |
-
2011
- 2011-12-22 RU RU2013133788/04A patent/RU2013133788A/ru unknown
- 2011-12-22 MX MX2013007292A patent/MX2013007292A/es unknown
- 2011-12-22 BR BR112013015869A patent/BR112013015869A2/pt not_active IP Right Cessation
- 2011-12-22 NZ NZ613333A patent/NZ613333A/en not_active IP Right Cessation
- 2011-12-22 JP JP2013545415A patent/JP5934246B2/ja not_active Expired - Fee Related
- 2011-12-22 EP EP11805036.8A patent/EP2655353B9/en not_active Not-in-force
- 2011-12-22 WO PCT/EP2011/073822 patent/WO2012085221A1/en not_active Ceased
- 2011-12-22 CN CN201180062006.6A patent/CN103328460B/zh not_active Expired - Fee Related
- 2011-12-22 US US13/823,237 patent/US9175044B2/en active Active
- 2011-12-22 CA CA2822097A patent/CA2822097C/en active Active