JP2014162761A5 - - Google Patents

Info

Publication number

JP2014162761A5

JP2014162761A5 JP2013035845A JP2013035845A JP2014162761A5 JP 2014162761 A5 JP2014162761 A5 JP 2014162761A5 JP 2013035845 A JP2013035845 A JP 2013035845A JP 2013035845 A JP2013035845 A JP 2013035845A JP 2014162761 A5 JP2014162761 A5 JP 2014162761A5

Authority

JP

Japan

Prior art keywords

preventing

skin

function

tiopronin

alacepril

Prior art date

2013-02-26

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
• Global Dossier
• Discuss

• GLZPCOQZEFWAFX-UHFFFAOYSA-N Geraniol Chemical compound CC(C)=CCCC(C)=CCO GLZPCOQZEFWAFX-UHFFFAOYSA-N 0.000 claims 6
• YKGYIDJEEQRWQH-UHFFFAOYSA-N 4-[6-(diaminomethylideneamino)-1-oxohexoxy]benzoic acid ethyl ester Chemical compound CCOC(=O)C1=CC=C(OC(=O)CCCCCN=C(N)N)C=C1 YKGYIDJEEQRWQH-UHFFFAOYSA-N 0.000 claims 3
• FHHHOYXPRDYHEZ-COXVUDFISA-N Alacepril Chemical compound CC(=O)SC[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(O)=O)CC1=CC=CC=C1 FHHHOYXPRDYHEZ-COXVUDFISA-N 0.000 claims 3
• UDMBCSSLTHHNCD-UHFFFAOYSA-N Coenzym Q(11) Natural products C1=NC=2C(N)=NC=NC=2N1C1OC(COP(O)(O)=O)C(O)C1O UDMBCSSLTHHNCD-UHFFFAOYSA-N 0.000 claims 3
• DYDCUQKUCUHJBH-UWTATZPHSA-N D-Cycloserine Chemical compound N[C@@H]1CONC1=O DYDCUQKUCUHJBH-UWTATZPHSA-N 0.000 claims 3
• DYDCUQKUCUHJBH-UHFFFAOYSA-N D-Cycloserine Natural products NC1CONC1=O DYDCUQKUCUHJBH-UHFFFAOYSA-N 0.000 claims 3
• GLZPCOQZEFWAFX-YFHOEESVSA-N Geraniol Natural products CC(C)=CCC\C(C)=C/CO GLZPCOQZEFWAFX-YFHOEESVSA-N 0.000 claims 3
• 239000005792 Geraniol Substances 0.000 claims 3
• 108010007859 Lisinopril Proteins 0.000 claims 3
• FXHOOIRPVKKKFG-UHFFFAOYSA-N N,N-Dimethylacetamide Chemical compound CN(C)C(C)=O FXHOOIRPVKKKFG-UHFFFAOYSA-N 0.000 claims 3
• KDYFGRWQOYBRFD-UHFFFAOYSA-N Succinic acid Natural products OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 claims 3
• YTGJWQPHMWSCST-UHFFFAOYSA-N Tiopronin Chemical compound CC(S)C(=O)NCC(O)=O YTGJWQPHMWSCST-UHFFFAOYSA-N 0.000 claims 3
• 108010058907 Tiopronin Proteins 0.000 claims 3
• 239000004480 active ingredient Substances 0.000 claims 3
• UDMBCSSLTHHNCD-KQYNXXCUSA-N adenosine 5'-monophosphate Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O UDMBCSSLTHHNCD-KQYNXXCUSA-N 0.000 claims 3
• LNQVTSROQXJCDD-UHFFFAOYSA-N adenosine monophosphate Natural products C1=NC=2C(N)=NC=NC=2N1C1OC(CO)C(OP(O)(O)=O)C1O LNQVTSROQXJCDD-UHFFFAOYSA-N 0.000 claims 3
• 229960003190 adenosine monophosphate Drugs 0.000 claims 3
• 229950007884 alacepril Drugs 0.000 claims 3
• KDYFGRWQOYBRFD-NUQCWPJISA-N butanedioic acid Chemical compound O[14C](=O)CC[14C](O)=O KDYFGRWQOYBRFD-NUQCWPJISA-N 0.000 claims 3
• FHRSHSOEWXUORL-HDJSIYSDSA-N cetraxate Chemical compound C1C[C@@H](C[NH3+])CC[C@@H]1C(=O)OC1=CC=C(CCC([O-])=O)C=C1 FHRSHSOEWXUORL-HDJSIYSDSA-N 0.000 claims 3
• 229950009533 cetraxate Drugs 0.000 claims 3
• 239000003795 chemical substances by application Substances 0.000 claims 3
• DNTGGZPQPQTDQF-XBXARRHUSA-N crotamiton Chemical compound C/C=C/C(=O)N(CC)C1=CC=CC=C1C DNTGGZPQPQTDQF-XBXARRHUSA-N 0.000 claims 3
• 229960003338 crotamiton Drugs 0.000 claims 3
• 229960003077 cycloserine Drugs 0.000 claims 3
• 229960003964 deoxycholic acid Drugs 0.000 claims 3
• KXGVEGMKQFWNSR-LLQZFEROSA-N deoxycholic acid Chemical compound C([C@H]1CC2)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)[C@@H](O)C1 KXGVEGMKQFWNSR-LLQZFEROSA-N 0.000 claims 3
• 229940031569 diisopropyl sebacate Drugs 0.000 claims 3
• XFKBBSZEQRFVSL-UHFFFAOYSA-N dipropan-2-yl decanedioate Chemical compound CC(C)OC(=O)CCCCCCCCC(=O)OC(C)C XFKBBSZEQRFVSL-UHFFFAOYSA-N 0.000 claims 3
• BEFDCLMNVWHSGT-UHFFFAOYSA-N ethenylcyclopentane Chemical compound C=CC1CCCC1 BEFDCLMNVWHSGT-UHFFFAOYSA-N 0.000 claims 3
• 229950000501 gabexate Drugs 0.000 claims 3
• 229940113087 geraniol Drugs 0.000 claims 3
• MOYKHGMNXAOIAT-JGWLITMVSA-N isosorbide dinitrate Chemical compound [O-][N+](=O)O[C@H]1CO[C@@H]2[C@H](O[N+](=O)[O-])CO[C@@H]21 MOYKHGMNXAOIAT-JGWLITMVSA-N 0.000 claims 3
• 229960000201 isosorbide dinitrate Drugs 0.000 claims 3
• RLAWWYSOJDYHDC-BZSNNMDCSA-N lisinopril Chemical compound C([C@H](N[C@@H](CCCCN)C(=O)N1[C@@H](CCC1)C(O)=O)C(O)=O)CC1=CC=CC=C1 RLAWWYSOJDYHDC-BZSNNMDCSA-N 0.000 claims 3
• 229960002394 lisinopril Drugs 0.000 claims 3
• 229940075582 sorbic acid Drugs 0.000 claims 3
• 235000010199 sorbic acid Nutrition 0.000 claims 3
• 239000004334 sorbic acid Substances 0.000 claims 3
• 229960004402 tiopronin Drugs 0.000 claims 3
• 210000003491 skin Anatomy 0.000 claims 2
• 230000004215 skin function Effects 0.000 claims 2
• 206010003645 Atopy Diseases 0.000 claims 1
• 206010012438 Dermatitis atopic Diseases 0.000 claims 1
• 206010013786 Dry skin Diseases 0.000 claims 1
• 201000008937 atopic dermatitis Diseases 0.000 claims 1
• 239000008280 blood Substances 0.000 claims 1
• 210000004369 blood Anatomy 0.000 claims 1
• 230000006866 deterioration Effects 0.000 claims 1
• 201000010099 disease Diseases 0.000 claims 1
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
• 210000002615 epidermis Anatomy 0.000 claims 1
• 230000037406 food intake Effects 0.000 claims 1
• 230000006870 function Effects 0.000 claims 1
• 230000036737 immune function Effects 0.000 claims 1
• 230000003020 moisturizing effect Effects 0.000 claims 1
• 230000009759 skin aging Effects 0.000 claims 1
• 230000008591 skin barrier function Effects 0.000 claims 1
• 239000000126 substance Substances 0.000 claims 1