JP2014122240A5 - - Google Patents
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- JP2014122240A5 JP2014122240A5 JP2014061270A JP2014061270A JP2014122240A5 JP 2014122240 A5 JP2014122240 A5 JP 2014122240A5 JP 2014061270 A JP2014061270 A JP 2014061270A JP 2014061270 A JP2014061270 A JP 2014061270A JP 2014122240 A5 JP2014122240 A5 JP 2014122240A5
- Authority
- JP
- Japan
- Prior art keywords
- alkoxy
- compound
- disease
- compound according
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 8
- 125000003545 alkoxy group Chemical group 0.000 claims 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 4
- 125000000217 alkyl group Chemical group 0.000 claims 3
- 229910052739 hydrogen Inorganic materials 0.000 claims 3
- 239000001257 hydrogen Substances 0.000 claims 3
- 208000023275 Autoimmune disease Diseases 0.000 claims 2
- 208000024172 Cardiovascular disease Diseases 0.000 claims 2
- 206010061218 Inflammation Diseases 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 230000002159 abnormal effect Effects 0.000 claims 2
- 125000002252 acyl group Chemical group 0.000 claims 2
- 125000005256 alkoxyacyl group Chemical group 0.000 claims 2
- 125000003282 alkyl amino group Chemical group 0.000 claims 2
- 125000000266 alpha-aminoacyl group Chemical group 0.000 claims 2
- 125000003118 aryl group Chemical group 0.000 claims 2
- 125000004104 aryloxy group Chemical group 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 230000004663 cell proliferation Effects 0.000 claims 2
- 125000004663 dialkyl amino group Chemical group 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 125000001072 heteroaryl group Chemical group 0.000 claims 2
- 150000002431 hydrogen Chemical class 0.000 claims 2
- 230000004054 inflammatory process Effects 0.000 claims 2
- 230000028709 inflammatory response Effects 0.000 claims 2
- 125000001181 organosilyl group Chemical group [SiH3]* 0.000 claims 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 2
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 claims 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 125000004183 alkoxy alkyl group Chemical group 0.000 claims 1
- 150000001768 cations Chemical class 0.000 claims 1
- 125000005207 tetraalkylammonium group Chemical group 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/093,757 US7582785B2 (en) | 2002-04-01 | 2005-03-29 | Trihydroxy polyunsaturated eicosanoid derivatives |
| US11/093,757 | 2005-03-29 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012128022A Division JP2012162576A (ja) | 2005-03-29 | 2012-06-05 | トリヒドロキシポリ不飽和エイコサノイド誘導体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014122240A JP2014122240A (ja) | 2014-07-03 |
| JP2014122240A5 true JP2014122240A5 (enExample) | 2014-10-02 |
Family
ID=36645579
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008504239A Pending JP2008538117A (ja) | 2005-03-29 | 2006-03-28 | トリヒドロキシポリ不飽和エイコサノイド誘導体 |
| JP2012128022A Pending JP2012162576A (ja) | 2005-03-29 | 2012-06-05 | トリヒドロキシポリ不飽和エイコサノイド誘導体 |
| JP2014061270A Pending JP2014122240A (ja) | 2005-03-29 | 2014-03-25 | トリヒドロキシポリ不飽和エイコサノイド誘導体 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008504239A Pending JP2008538117A (ja) | 2005-03-29 | 2006-03-28 | トリヒドロキシポリ不飽和エイコサノイド誘導体 |
| JP2012128022A Pending JP2012162576A (ja) | 2005-03-29 | 2012-06-05 | トリヒドロキシポリ不飽和エイコサノイド誘導体 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7582785B2 (enExample) |
| EP (1) | EP1863753B1 (enExample) |
| JP (3) | JP2008538117A (enExample) |
| CN (1) | CN101203481A (enExample) |
| AU (1) | AU2006230136B2 (enExample) |
| BR (1) | BRPI0609767A2 (enExample) |
| CA (1) | CA2603371C (enExample) |
| MX (2) | MX2007012022A (enExample) |
| WO (1) | WO2006105058A2 (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL151299A0 (en) * | 2000-02-16 | 2003-04-10 | Brigham & Womens Hospital | Aspirin-triggered lipid mediators |
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| US7582785B2 (en) | 2002-04-01 | 2009-09-01 | University Of Southern California | Trihydroxy polyunsaturated eicosanoid derivatives |
| US7902257B2 (en) | 2002-04-01 | 2011-03-08 | University Of Southern California | Trihydroxy polyunsaturated eicosanoid |
| US8481772B2 (en) | 2002-04-01 | 2013-07-09 | University Of Southern California | Trihydroxy polyunsaturated eicosanoid derivatives |
| DK2216318T3 (en) | 2002-08-12 | 2018-12-10 | Brigham & Womens Hospital | Resolvins: Bio templates for therapeutic interventions |
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| EP1755537A4 (en) * | 2004-04-14 | 2009-12-09 | Univ Boston | METHOD AND COMPOSITIONS FOR PREVENTING OR TREATING PERIODONTOPATHIA |
| US7893106B2 (en) * | 2004-11-19 | 2011-02-22 | Martek Biosciences, Corporation | Oxylipins from stearidonic acid and γ-linolenic acid and methods of making and using the same |
| KR20070090928A (ko) * | 2004-11-19 | 2007-09-06 | 마텍 바이오싸이언스스 코포레이션 | 장쇄 다가불포화 지방산으로부터의 옥시리핀, 및 이의 제조방법 및 사용 방법 |
| US20090318394A1 (en) * | 2004-11-19 | 2009-12-24 | Julie Nauroth | Long Chain Polyunsaturated Fatty Acids and Methods of Making and Using the Same |
| US20060293288A1 (en) * | 2005-01-07 | 2006-12-28 | Serhan Charles N | Use of resolvins to treat gastrointestinal diseases |
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| US8636986B2 (en) * | 2005-11-18 | 2014-01-28 | The Forsyth Institute | Treatment and prevention of bone loss using resolvins |
| WO2007090162A2 (en) * | 2006-01-31 | 2007-08-09 | Martek Biosciences Corporation | OXYLIPINS FROM STEARIDONIC ACID AND γ-LINOLENIC ACID AND METHODS OF MAKING AND USING THE SAME |
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| US20110190389A1 (en) * | 2007-02-20 | 2011-08-04 | Linda Arterburn | Oxylipins from long chain polyunsaturated fatty acids and methods of making and using the same |
| CA2699483A1 (en) * | 2007-09-14 | 2009-03-26 | Resolvyx Pharmaceuticals, Inc. | Compositions and methods for modulating immune function |
| KR20150115959A (ko) * | 2007-10-12 | 2015-10-14 | 레솔빅스 파마슈티칼즈, 인코퍼레이티드 | 안과 질환의 치료를 위한 옥실리핀 화합물 |
| US20110027841A1 (en) * | 2007-12-21 | 2011-02-03 | Martek Biosciences Corporation | Method for preparation of oxylipins |
| US20110190242A1 (en) * | 2008-09-23 | 2011-08-04 | Resolvyx Pharmaceuticals, Inc. | Compositions and methods for the treatment of inflammatory disease |
| WO2010095706A1 (ja) | 2009-02-20 | 2010-08-26 | 国立大学法人東京大学 | 新規抗炎症性化合物 |
| TW201039815A (en) * | 2009-04-13 | 2010-11-16 | Resolvyx Pharmaceuticals Inc | Compositions and methods for the treatment of inflammation |
| JP5184565B2 (ja) * | 2010-03-10 | 2013-04-17 | 独立行政法人科学技術振興機構 | 水系溶媒中での含窒素化合物の製造方法 |
| CN103396350B (zh) * | 2012-01-09 | 2014-11-05 | 浙江师范大学 | 一种利用顺式-1-卤-2-氯代烯烃合成维生素a的方法 |
| PL2887923T3 (pl) | 2012-08-24 | 2023-08-14 | Sun Pharmaceutical Industries Limited | Preparat okulistyczny polioksylipidu lub polioksylowego kwasu tłuszczowego i leczenie chorób oczu |
| AU2014205369B2 (en) | 2013-01-11 | 2018-08-09 | Massachusetts Eye And Ear Infirmary | CYP450 lipid metabolites reduce inflammation and angiogenesis |
| WO2014115098A1 (en) * | 2013-01-26 | 2014-07-31 | Mahesh Kandula | Compositions and methods for the treatment of neurological diseases and inflammation |
| US9682034B2 (en) | 2015-03-10 | 2017-06-20 | Elc Management Llc | Methods and compositions for treating skin to resolve inflammation and screening for actives that stimulate pro-resolution pathways |
| ES2895062T3 (es) | 2015-03-18 | 2022-02-17 | Forsyth Dental Infirmary For Children | Métodos para estabilizar placas ateroscleróticas usando lipoxinas, resolvinas y análogos de las mismas |
| JP2018532809A (ja) | 2015-11-10 | 2018-11-08 | サン ファーマ グローバル エフジーイー | 局所製剤およびその使用 |
| EP3950649A1 (en) * | 2015-11-23 | 2022-02-09 | Retrotope, Inc. | Site-specific isotopic labeling of 1, 4-diene systems |
| US11903998B2 (en) | 2016-05-27 | 2024-02-20 | Forsyth Dental Infirmary For Children | Compositions and methods of treating cancer using lipid agonists and receptors thereof |
| KR20220143931A (ko) | 2020-02-21 | 2022-10-25 | 레트로토프 인코포레이티드 | 고도불포화 지방산 및 이의 유도체의 동위원소 변형을 위한 공정 |
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| DK2216318T3 (en) | 2002-08-12 | 2018-12-10 | Brigham & Womens Hospital | Resolvins: Bio templates for therapeutic interventions |
| US7759395B2 (en) | 2002-08-12 | 2010-07-20 | The Brigham And Women's Hospital, Inc. | Use of docosatrienes, resolvins and their stable analogs in the treatment of airway diseases and asthma |
| WO2004078143A2 (en) | 2003-03-05 | 2004-09-16 | The Brigham And Women's Hospital Inc. | Methods for identification and uses of anti-inflammatory receptors for eicosapentaenoic acid analogs |
| US20060293288A1 (en) | 2005-01-07 | 2006-12-28 | Serhan Charles N | Use of resolvins to treat gastrointestinal diseases |
| KR20150115959A (ko) * | 2007-10-12 | 2015-10-14 | 레솔빅스 파마슈티칼즈, 인코퍼레이티드 | 안과 질환의 치료를 위한 옥실리핀 화합물 |
| WO2010039531A1 (en) * | 2008-09-23 | 2010-04-08 | Resolvyx Pharmaceuticals, Inc. | Therapeutic compounds |
| US20120122816A1 (en) * | 2009-02-05 | 2012-05-17 | Resolvyx Pharmaceuticals, Inc. | Compositions and methods for organ preservation |
| TW201039815A (en) * | 2009-04-13 | 2010-11-16 | Resolvyx Pharmaceuticals Inc | Compositions and methods for the treatment of inflammation |
-
2005
- 2005-03-29 US US11/093,757 patent/US7582785B2/en not_active Expired - Fee Related
-
2006
- 2006-03-28 MX MX2007012022A patent/MX2007012022A/es active IP Right Grant
- 2006-03-28 WO PCT/US2006/011222 patent/WO2006105058A2/en not_active Ceased
- 2006-03-28 EP EP06748789.2A patent/EP1863753B1/en not_active Not-in-force
- 2006-03-28 AU AU2006230136A patent/AU2006230136B2/en not_active Ceased
- 2006-03-28 CN CNA2006800180987A patent/CN101203481A/zh active Pending
- 2006-03-28 MX MX2014005826A patent/MX352197B/es unknown
- 2006-03-28 CA CA2603371A patent/CA2603371C/en not_active Expired - Fee Related
- 2006-03-28 JP JP2008504239A patent/JP2008538117A/ja active Pending
- 2006-03-28 BR BRPI0609767-7A patent/BRPI0609767A2/pt not_active Application Discontinuation
-
2012
- 2012-06-05 JP JP2012128022A patent/JP2012162576A/ja active Pending
-
2014
- 2014-03-25 JP JP2014061270A patent/JP2014122240A/ja active Pending
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