AU2006230136B2 - Trihydroxy polyunsaturated eicosanoid derivatives - Google Patents

Trihydroxy polyunsaturated eicosanoid derivatives Download PDF

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Publication number
AU2006230136B2
AU2006230136B2 AU2006230136A AU2006230136A AU2006230136B2 AU 2006230136 B2 AU2006230136 B2 AU 2006230136B2 AU 2006230136 A AU2006230136 A AU 2006230136A AU 2006230136 A AU2006230136 A AU 2006230136A AU 2006230136 B2 AU2006230136 B2 AU 2006230136B2
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AU
Australia
Prior art keywords
aryl
alkyl
heteroaryl
perfluoroalkyl
hydrogen
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Ceased
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AU2006230136A
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AU2006230136A1 (en
Inventor
Nicos A. Petasis
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University of Southern California USC
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University of Southern California USC
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Publication of AU2006230136A1 publication Critical patent/AU2006230136A1/en
Application granted granted Critical
Publication of AU2006230136B2 publication Critical patent/AU2006230136B2/en
Priority to AU2012200616A priority Critical patent/AU2012200616B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/303—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by hydrogenation of unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C07F7/1872—Preparation; Treatments not provided for in C07F7/20
    • C07F7/1892—Preparation; Treatments not provided for in C07F7/20 by reactions not provided for in C07F7/1876 - C07F7/1888
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05—Isotopically modified compounds, e.g. labelled

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
AU2006230136A 2005-03-29 2006-03-28 Trihydroxy polyunsaturated eicosanoid derivatives Ceased AU2006230136B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2012200616A AU2012200616B2 (en) 2005-03-29 2012-02-03 Trihydroxy polyunsaturated eicosanoid derivatives

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/093,757 US7582785B2 (en) 2002-04-01 2005-03-29 Trihydroxy polyunsaturated eicosanoid derivatives
US11/093,757 2005-03-29
PCT/US2006/011222 WO2006105058A2 (en) 2005-03-29 2006-03-28 Trihydroxy polyunsaturated eicosanoid derivatives

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2012200616A Division AU2012200616B2 (en) 2005-03-29 2012-02-03 Trihydroxy polyunsaturated eicosanoid derivatives

Publications (2)

Publication Number Publication Date
AU2006230136A1 AU2006230136A1 (en) 2006-10-05
AU2006230136B2 true AU2006230136B2 (en) 2011-11-03

Family

ID=36645579

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2006230136A Ceased AU2006230136B2 (en) 2005-03-29 2006-03-28 Trihydroxy polyunsaturated eicosanoid derivatives

Country Status (9)

Country Link
US (1) US7582785B2 (enExample)
EP (1) EP1863753B1 (enExample)
JP (3) JP2008538117A (enExample)
CN (1) CN101203481A (enExample)
AU (1) AU2006230136B2 (enExample)
BR (1) BRPI0609767A2 (enExample)
CA (1) CA2603371C (enExample)
MX (2) MX352197B (enExample)
WO (1) WO2006105058A2 (enExample)

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WO2003053423A2 (en) * 2001-12-18 2003-07-03 The Brigham And Women's Hospital Inhibition or prevention of infection by bacteria with epa, dha or analogs
US7902257B2 (en) * 2002-04-01 2011-03-08 University Of Southern California Trihydroxy polyunsaturated eicosanoid
US7582785B2 (en) * 2002-04-01 2009-09-01 University Of Southern California Trihydroxy polyunsaturated eicosanoid derivatives
US8481772B2 (en) 2002-04-01 2013-07-09 University Of Southern California Trihydroxy polyunsaturated eicosanoid derivatives
US7759395B2 (en) 2002-08-12 2010-07-20 The Brigham And Women's Hospital, Inc. Use of docosatrienes, resolvins and their stable analogs in the treatment of airway diseases and asthma
AU2003258194B2 (en) * 2002-08-12 2009-11-12 The Brigham And Women's Hospital, Inc. Resolvins: biotemplates for therapeutic interventions
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JP6526570B2 (ja) 2013-01-11 2019-06-12 マサチューセッツ アイ アンド イヤー インファーマリー 炎症及び血管形成を減少させるｃｙｐ４５０脂質メタボライト
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CN107438366B (zh) 2015-03-18 2022-03-15 福塞斯儿童牙科医院 使用脂氧素、消退素及其类似物稳定动脉粥状硬化斑块的方法
PL3373976T3 (pl) 2015-11-10 2024-06-24 Sun Pharmaceutical Industries Limited Preparaty do stosowania miejscowego i ich zastosowanie
CN108698987B (zh) 2015-11-23 2021-07-13 乐巢拓普有限公司 1,4-二烯体系的位点特异性同位素标记
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Also Published As

Publication number Publication date
WO2006105058A2 (en) 2006-10-05
CA2603371C (en) 2013-05-28
JP2012162576A (ja) 2012-08-30
CN101203481A (zh) 2008-06-18
EP1863753A2 (en) 2007-12-12
US20050228047A1 (en) 2005-10-13
JP2014122240A (ja) 2014-07-03
EP1863753B1 (en) 2017-09-20
MX352197B (es) 2017-11-13
AU2006230136A1 (en) 2006-10-05
US7582785B2 (en) 2009-09-01
BRPI0609767A2 (pt) 2010-04-27
CA2603371A1 (en) 2006-10-05
JP2008538117A (ja) 2008-10-09
WO2006105058A3 (en) 2007-04-12
MX2007012022A (es) 2011-06-16

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