JP2014068836A - Subject information detection unit, electrically-driven toothbrush, and electrically-driven shaver - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a subject information detection unit which is easily usable, has directivity in sensing without requiring accuracy of the positional relationship between a sensor and a blood vessel, and shows an excellent detection sensitivity.SOLUTION: A subject information detection unit comprises: a casing part 11 or 21 which has an outer shape to allow a subject to grasp with a hand, and is structured as a columnar member or an egg-shaped member; and a first sensor 14 which is held in the casing part 11 or 21, and detects a pulsating signal of a blood vessel in a finger 91 of the hand grasping the casing part 11 or 21.

Description

  The present invention has a sample information detection unit that has an outer shape that can be grasped by the hand of a sample, detects a pulsation signal of a blood vessel in a finger of the hand, and an electric toothbrush device and an electric shaver provided with the sample information detection unit Relates to the device.

  Sensors that detect pulsating signals of arms with relatively thick blood vessels in them or fingertips with capillaries stretched like a net have a structure with a closed space. The heart is transmitted through the blood vessel by applying pressure to the skin of the arm or fingertip at a very weak level that does not obstruct the flow of blood vessels, and placing a pressure sensor such as a condenser microphone on the other side. 2. Description of the Related Art A pressure sensor device that detects a pulse wave caused by a pulsation of a pressure as a pressure change in a closed space is known.

  Patent Document 1 (Japanese Patent Laid-Open No. 2001-178691) has a structure in which the thickness (height) of a finger of a patient to be examined is kept constant via a pressure sensor at a fingernail portion and a target position thereof. An apparatus for evaluating a circulatory system is disclosed in which a pulse wave sensor is mounted and the pressure sensor of the pulse wave sensor obtains, as an electrical signal, the expansion and contraction of the skin due to blood flow from the first joint of the examinee's finger to the periphery. .

  In patent document 2 (Unexamined-Japanese-Patent No. 11-56799), it has the press surface pressed by the cervical part of a biological body, the several pressure sensor which detects the pressure in this press surface, and the housing which hold | maintains in the state which arranged the pressure sensor And a housing attachment device for attaching the housing to the neck of a living body, and a carotid artery pressure wave detection device that detects pressure waves in the carotid artery of the neck by being pressed by the neck.

Japanese Patent Laid-Open No. 2001-178691 Japanese Patent Laid-Open No. 11-56799

In the case of the above-mentioned patent document 1, the thickness of the nail part is maintained by fixing the pressure sensor case of the pulse wave sensor to the subject's finger with an additional band magic tape (registered trademark). In order to obtain a wave signal, it was necessary to fix the pulse wave sensor.
In the case of the above-mentioned Patent Document 2, a carotid artery pressure wave is provided in a state in which the housing is mounted on the cervical part of a living body by a gripping device 12 that includes a member made of an elastically deformable leaf spring material that extends in a curved manner and functions as a housing mounting device. It was necessary to measure.

  When detecting a pulsation signal, a device that performs detection by fixing a pressure sensor and a detection device to a sample as in Patent Documents 1 and 2 above, for example, performs measurement quickly when an abnormality is felt in the body. In some cases, it may be difficult, or it may seem complicated when taking measurements at similar times on a regular basis. For this reason, there has been a demand for a pulsating signal detection device that does not require fixation during measurement and has sufficient detection performance.

  The present invention has been made in view of such problems, and an object thereof is to provide a specimen information detection unit that can be used easily.

In order to achieve the above object, the specimen information detection unit of the present invention has a casing having an outer shape that can be grasped by the hand of the specimen, and the casing is configured as a columnar member or an egg-shaped member. The first sensor for detecting a pulsation signal of a blood vessel in the finger of the hand gripping the casing is provided in the casing.
At this time, a first opening having a diameter of 3 mm to 8 mm is formed at a portion of the casing that should be opposed to the finger of the hand that has gripped the casing, and communicated with the first opening. In addition, a first cavity having a closed space structure is formed in the casing portion in a state where the first opening portion is opposed to the finger and the casing portion is gripped by the hand, and the first sensor is formed. However, the pulsation signal of the blood vessel in the finger inputted through the first opening may be detected as pressure information propagating in the first cavity due to the pulsation signal.
Furthermore, a guide groove for the finger may be formed on the front wall portion of the housing, and the opening may be formed in the guide groove.
A first light source provided on the casing unit that generates an optical signal toward the finger of the hand that grips the casing unit; and the finger that faces the finger of the hand that grips the casing unit. A light transmitting portion made of a transparent material that can transmit an optical signal from the first light source, and a finger of a hand gripping the housing portion is attached to the housing portion. An optical signal from the first light source is transmitted through the light transmission part and hits the finger, and an optical signal reflected by the finger is transmitted through the light transmission part and is opposite to the light transmission part provided. The first sensor detects a pulsation signal of a blood vessel in the finger, and an optical signal reflected by the optical signal from the first light source due to the pulsation signal reflected on the finger. You may comprise so that it may detect by receiving light.
Furthermore, a guide groove for the finger may be formed in the front wall portion of the housing portion, and the light transmission portion may be provided in the guide groove.

Another gist of the present invention is provided with a casing having an outer shape that can be grasped by the hand of a specimen, the casing is configured as a columnar member or an egg-shaped member, and is provided in the casing. The specimen information detection unit is provided with a plurality of first sensors for detecting blood vessel pulsation signals in a plurality of fingers of the hand holding the casing.
At this time, a first opening portion having a diameter of 3 mm to 8 mm is formed in each portion of the casing portion that should be opposed to each finger of the hand that has gripped the casing portion, and A plurality of first cavities that communicate with the first opening and that have a spatial structure that is closed in a state where the first opening is opposed to the respective fingers and the housing is gripped by the hand. The pulsating signal of the blood vessel in each finger input through the first opening is formed in the casing and the pulsating signal of the blood vessel in the first cavity is caused by the pulsating signal. It may be configured to detect as pressure information propagating.
Furthermore, the guide groove of each finger may be formed on the front wall portion of the casing, and the opening may be formed in each guide groove.
A plurality of first light sources that are provided in the casing and generate optical signals toward the fingers of the hand that grips the casing; and the hand that grips the casing A plurality of light transmitting portions made of a transmissive material provided at a portion of the housing portion to be opposed to each of a plurality of fingers and capable of transmitting a light signal from the first light source. A plurality of fingers of the hand holding the light beam face each light transmitting portion provided in each guide groove, and an optical signal from each first light source passes through each light transmitting portion. Then, each of the above-mentioned first sensors is configured such that an optical signal that hits each of the fingers and is reflected by the finger is transmitted through the respective light transmitting portions and detected by the first sensors. The pulsation signal of the blood vessel in the finger of the above is caused by the optical signal from each of the first light sources due to the pulsation signal. It may be configured to be detected by receiving the light signal reflected against the finger respectively.
Furthermore, the guide groove of each said finger | toe may be formed in the front wall part of this housing | casing part, and this 1st sensor may be each provided in each said guide groove.
The first sensor may be a capacitor microphone or a PZT piezoelectric element.
Further, the first sensor may be a photodiode.

In addition, a sample detection sensor is provided in the casing, and when the sample is detected by the sample detection sensor, a sample notification that notifies the position of the casing due to an output from the sample detection sensor is provided. You may have a part.
In addition, a polarity determination unit that detects the polarity of the waveform of the pulsation signal detected by the first sensor is provided, and a polarity notification unit that notifies a change in polarity due to an output from the polarity determination unit. May be.
In addition, the casing portion is provided with a grip strength sensor for detecting the grip strength of the hand, and the grip strength for informing the grip strength of the hand due to an output from the grip strength sensor. An informing unit may be provided.
In addition, the housing unit may be provided with a storage unit that stores a measurement result by the first sensor.
Further, the casing may be provided with a clock and GPS, and the storage unit may be configured to store the measurement result of the clock and GPS and the measurement result of the first sensor in association with each other. .
Further, a sample temperature detecting means for detecting the temperature of the sample through the hand gripping the casing portion, an outside air temperature detecting means for detecting the outside air temperature, and the above-described sample temperature detecting means and the outside You may provide the memory | storage means which memorize | stores the measurement result with an air temperature detection means clock.
A second light source provided on the casing for generating an optical signal so as to pass through the finger; and receiving the optical signal from the light source provided on the casing and transmitted through the finger. In addition, a second sensor that detects information related to oxygen saturation in the blood vessel may be provided.
In addition, the housing has a second opening at a portion facing the sample, communicates with the opening, and is attached to the sample with the second opening facing the sample. A second cavity that forms a closed space structure is formed in the casing, is provided in the casing, passes through the second cavity of the casing, and passes through the second opening of the casing. A composite optical system including a plurality of light sources for supplying optical signals toward the blood vessels of the specimen, and signals from the blood vessels in the specimen affected by the optical signals to propagate through the second cavity A third sensor may be provided that receives the pressure information and detects information related to the blood glucose level in the blood vessel.
Further, a cradle may be provided that is mounted in a contact state or a non-contact state and has a function of reading a measurement signal from the housing unit and supplying power.

Another gist of the present invention resides in an electric toothbrush device, characterized in that the casing portion in the specimen information detection unit is a grip portion of the electric toothbrush device.
At this time, the cradle may also serve as the cradle for the electric toothbrush device.
Another gist of the present invention resides in an electric shaver device, characterized in that the casing portion in the sample information detection unit is a grip portion of the electric shaver device.
At this time, the cradle may also serve as the cradle for the electric shaver device.

  According to the present invention, it is possible to provide a specimen information detection unit that can quickly grasp a specimen information detection unit and provides a quick and stable detection result of a pulsation signal by stabilizing a gripping force with a hand. it can.

FIG. 2 illustrates a configuration of a specimen information detection unit in which a first opening and a first cavity according to a first embodiment of the present invention are formed, and (a) schematically illustrates a configuration in which a casing is cylindrical. (B) is a figure which represents typically the structure where a housing | casing part is egg-shaped. The structure of the sample information detection unit concerning 1st embodiment of this invention is represented typically, (a) is a figure showing typically the relationship between a finger | toe and the partial cross section figure of a sample information detection unit, (b) ) Is a diagram schematically illustrating the configuration around the first opening. It is a figure which represents typically an example of the circuit structure of the PZT element as a 1st sensor. It is a figure which represents typically an example of a structure of the photo interrupter as a 1st sensor. It is a figure which shows typically the response waveform of the pulse wave detected by the photo interrupter as a 1st sensor. It is a figure which represents typically the structure of the sample alerting | reporting part in the sample information detection unit concerning 1st embodiment of this invention. It is a figure which shows typically an example of the change of the pulse wave accompanying the change of the force to press. It is a block diagram for demonstrating the function structure of the signal processing part of the sample information detection unit concerning 1st embodiment of this invention. It is a figure for demonstrating an example of the process of the waveform by a peak hold circuit and a bottom hold circuit, (a) is a figure showing the waveform before a process, (b) is a circuit of the circuit after the bottom hold process by a bottom hold circuit. The figure showing an output, (c) is the figure showing the output of the circuit after the peak hold processing by the peak hold circuit, (d) is the figure showing what detected the high frequency part from the waveform of Fig.9 (a) by the band pass filter. It is. It is a figure which shows an example of the change of the waveform of a pulse wave when changing the force to press, (a) is a figure showing the waveform of the pulse wave when weak force is applied, (b) is applying strong force. It is a figure showing the waveform of the pulse wave in the case of having done. It is a figure for demonstrating an example of adjustment of the press from the waveform of a pulse wave, (a) is a figure showing the volume pulse wave detected by the 1st sensor, (b) is the speed detected by the 1st sensor. The figure showing a pulse wave, (c) The figure showing the timing in 1 period of a pulse wave, (d) The figure showing the timing of PLL input, (e) The 2nd peak in the case of the appropriate pressure of a velocity pulse wave (F) is an acceleration pulse wave when the pressure is high, (g) is an acceleration pulse wave when the pressure is high, and (h) is an acceleration pulse wave when the pressure is low. FIG. FIG. 2 illustrates a configuration of a specimen information detection unit according to a first modification of the first embodiment of the present invention, in which (a) schematically illustrates a configuration in which a casing is cylindrical, and (b) is a casing. FIG. 3 is a diagram schematically illustrating an egg-shaped configuration. It is a block diagram for demonstrating the function structure of the averaging process part which averages the some signal in the sample information detection unit concerning the 1st modification of 1st embodiment of this invention. It is a figure which represents typically an example of a structure of the 2nd light source and 2nd sensor in the sample information detection unit concerning 2nd embodiment of this invention. It is a figure which represents typically an example of the synthetic | combination optical system and the 3rd sensor in the sample information detection unit concerning 2nd embodiment of this invention. It is a figure which shows the waveform for demonstrating an example of the control of the signal in the light emission control part in the sample information detection unit concerning 2nd embodiment of this invention, (a) is the timing based on 1 period of a pulse wave. FIGS. 8A to 8B are diagrams for explaining an example of control of a signal for measuring oxygen saturation, and FIGS. 8C to 24C are examples of control of a signal for measuring a blood glucose level. FIG. It is a figure showing an example of the waveform produced when the first embodiment of the present invention is applied to an electric shaver device, (a) is a figure showing the waveform of the noise component of an electric shaver device, and (b) is detected from the fingertip. The figure showing the waveform of the volume pulse wave of a pulsation signal, (c) is a figure showing the waveform of the velocity pulse wave of the pulsation signal detected from the fingertip. BRIEF DESCRIPTION OF THE DRAWINGS It is a figure showing an example of the waveform produced when 1st embodiment of this invention is applied to an electric toothbrush apparatus, (a) is a figure showing the waveform of the noise component of an electric toothbrush apparatus, (b) is detected from the fingertip. The figure showing the waveform of the volume pulse wave of a pulsation signal, (c) is a figure showing the waveform of the velocity pulse wave of the pulsation signal detected from the fingertip. It is a figure which shows an example of the relationship between the aperture of the 1st opening part of a sample information detection unit, and the strength of a signal. FIG. 2 illustrates a configuration of a specimen information detection unit provided with a light transmission unit according to the first embodiment of the present invention, in which (a) is a diagram schematically illustrating a configuration in which a casing is cylindrical, and (b) is a diagram. It is a figure which represents typically an egg shaped composition of a case part. FIG. 4 illustrates a configuration of a sample information detection unit provided with a light transmission unit according to a second embodiment of the present invention, in which (a) schematically illustrates a configuration in which a casing has a columnar shape, and (b). It is a figure which represents typically an egg shaped composition of a case part. It is a figure showing the typical structure at the time of applying the first embodiment of the present invention to an electric shaver device. It is a block diagram for demonstrating an example of a function structure of the sample information detection unit concerning 1st embodiment of this invention. It is a block diagram for demonstrating an example of a function structure of the sample information detection unit concerning 1st embodiment of this invention. It is a block diagram for demonstrating an example of a function structure of the sample information detection unit concerning the 1st modification of 1st embodiment of this invention. It is a block diagram for demonstrating an example of a function structure of the sample information detection unit concerning the 1st modification of 1st embodiment of this invention. It is a block diagram for demonstrating an example of a function structure of the sample information detection unit concerning 2nd embodiment of this invention. It is a block diagram for demonstrating an example of a function structure of the sample information detection unit concerning the 1st modification of 2nd embodiment of this invention.

  Embodiments of the present invention will be described below with reference to the drawings. The present invention is not limited to the following embodiments, and can be arbitrarily modified and implemented without departing from the gist of the present invention.

[A1. Description of First Embodiment]
[1-1. Configuration example of sample information detection unit according to first embodiment]
Hereinafter, an example of the configuration of the sample information detection units 1, 3, 8, and 9 according to the first embodiment of the present invention will be described.

<Configuration of specimen information detection unit>
The sample information detection units 1 and 8 according to the first embodiment of the present invention include, as an example, a housing unit 11 as shown in FIGS. 1A and 20A, and the housing unit 11 is a circle. The first sensor 14 is provided as a columnar member. Alternatively, the specimen information detection units 3 and 9 according to the first embodiment of the present invention include a housing portion 21 as shown in FIGS. 1B and 20B, and the housing portion 21 has an egg shape. The first sensor 14 is provided as a member.

  In the sample information detection units 1 and 3 according to the first embodiment of the present invention, as shown in FIGS. 1A and 1B, first opening portions 12 are formed in the casing portions 11 and 21. In addition, it is preferable that the first cavity 13 is formed and the pressure sensitive element 24 functioning as the first sensor 14 is provided. Alternatively, the specimen information detection units 8 and 9 according to the first embodiment of the present invention include the first light source 17 and the housing parts 11 and 21 as shown in FIGS. 20 (a) and 20 (b). It is preferable that a light transmitting portion 23 and a light receiving element 18 functioning as the first sensor 14 are provided.

  Furthermore, the specimen information detection units 1, 3, 8, and 9 according to the first embodiment of the present invention are as shown in FIGS. 1 (a), 1 (b), 20 (a), and 20 (b). In addition, it is preferable that a finger guide groove 15 is formed on the front wall portion of the housing portions 11 and 21. It is preferable that the casing units 11 and 21 have a grip strength sensor 16.

  Moreover, it is preferable that the housing | casing parts 11 and 21 are provided with the signal processing part 101 which processes the signal detected with the 1st sensor 14 and the grip strength sensor 16 (FIG. 23, FIG. 24).

  In the present embodiment, the configuration of the sample information detection unit in the case where the housing part is gripped with the left hand will be described. However, as shown in FIGS. 1A, 1B, and 20A, the housing part is gripped with the right hand. ), The shape of the guide groove 15 shown in FIG.

In the present invention, when gripping the casing, the index finger, middle finger, ring finger, and little finger are oriented in substantially the same direction, and the index finger, middle finger, ring finger, and little finger are arced inward along the outer shape of the casing. Bend as you draw and bend the thumb, index finger, middle finger, ring finger, and little finger in a circle from the opposite side of the forefinger, middle finger, ring finger, and little finger along the outer shape of the housing. In this case, the case is held by wrapping the casing with five fingers of one hand.
The configuration of each part of the sample information detection unit 1, 3, 8, 9 according to the first embodiment of the present invention will be described below.

(Case)
The casing portions 11 and 21 have an outer shape that can be grasped by the specimen hand, and are portions that function as the casing of the specimen information detection units 1, 3, 8, and 9. As shown in FIGS. 1A and 1B, the housing portions 11 and 21 are formed with a first opening 12 and a first cavity 13, and function as a first sensor 14. 24 is provided. Alternatively, as shown in FIGS. 20A and 20B, the housing portions 11 and 21 include a first light source 17, a light transmission portion 23, and a light receiving element 18 that functions as the first sensor 14. Is provided

  The casing 11 is not limited in shape and size as long as it can be grasped by hand. However, in terms of ease of gripping and ease of holding, the case 11 is shown in FIGS. 1 (a) and 20 (a). As shown, the casing 11 of the specimen information detection units 1 and 8 is configured as a cylindrical or cylindrical member, and the first opening 12 and the first cavity 13 are formed in the side surface, and the first sensor It is preferable that a pressure-sensitive element 24 that functions as 14 is provided, or a light-receiving element 18 that functions as the first light source 17, the light transmitting portion 23, and the first sensor 14 is provided. In this case, it will be gripped by the hand along the circumferential surface of the casing 11. Alternatively, as shown in FIGS. 1 (b) and 20 (b), the casing 21 of the specimen information detection units 3 and 9 is configured as an egg-shaped member, and in the egg shape, near the center in the long side direction. The first opening 12 and the first cavity 13 are formed in a portion where the radius of curvature is large and the curve drawn by the shape of the end is gentle (hereinafter also simply referred to as the vicinity of the center). Preferably, the pressure element 24 is provided, or the first light source 17, the light transmission unit 23, and the light receiving element 18 that functions as the first sensor 14 are provided. In this case, it will be grasped by a hand along the circumferential direction near the center of the egg-shaped long side direction. Or the housing | casing part of the sample information detection unit may be comprised as a prismatic member.

The sizes of the casings 11 and 21 are preferably slightly larger from the extent that they can be wrapped by hand when grasped by hand. When the casing 11 is cylindrical, the circumference of the circumferential surface is determined by the thumb, the index finger, the middle finger, the ring finger, and the little finger when the casing 11 is gripped by a hand. It is preferable that the length is larger than one round. Further, when the casing 21 is egg-shaped, the circumferential length in the circumferential direction of the portion near the center in the long side direction is such that when the casing 21 is gripped by the hand, the thumb, index finger, and middle finger It is preferable that the length is larger than that of the ring finger and the little finger.
As long as the casings 11 and 21 have an external shape that can be grasped by the hand of the specimen, the inside may be formed hollow, or the inside may be filled and may be solid.

  According to the specimen information detection units 1, 3, 8, and 9 according to the first embodiment of the present invention, the casing parts 11 and 21 are formed in a columnar shape or an egg shape, so that the casing part has a natural shape. You can hold it with your hand.

(First opening)
As shown in FIG. 2A and FIG. 2B, the first opening 12 is formed in a portion of the casing 11, 21 that should face the finger 91 of the hand holding the casing 11, 21. It is formed by providing an opening, and is a part that comes into contact with the finger 91 of the hand when the casings 11 and 21 of the sample information detection units 1 and 3 are gripped by a hand. The first opening 12 is preferably formed in the finger guide groove 15. The first opening 12 communicates with the first cavity 13.

  The first opening portion 12 is a portion that is formed at a portion that should face the belly portion 92 of the finger 91 of the hand 91 when the housing portions 11 and 21 are gripped by the hand, and is in contact with the belly portion 92 of the finger 91 of the hand. It is preferable. The first opening 12 is more preferably formed at a site to be opposed to the skin portion corresponding to the joint portion of the finger 91 of the hand, and is opposed to the skin portion corresponding to the first joint portion of the finger 91 of the hand. It is particularly preferable that it is formed at the power site.

  FIG. 19 shows the signal when the pulsation signal of the capillary of the fingertip is measured while changing the diameter of the first opening 12 in the casings 11 and 21 when a condenser microphone is used as the first sensor 14. It is a figure showing strength.

  As is clear from FIG. 19, a signal can be measured when the diameter of the first opening 12 is 1 to 3 mm, but a sufficient gain is not obtained. It can be seen that the gain increases when the diameter of the first opening 12 is 3 mm or more, and the pulsation signal can be measured with a high gain when the diameter of the first opening 12 is 5 mm to 6 mm. This is considered to be due to the fact that when the aperture of the first opening 12 is smaller than 2 mm, the area for capturing the signal from the blood vessel is narrowed, so that the detected signal becomes weak. It is done.

  When the diameter of the first opening 12 is too large (for example, the diameter is larger than 10 mm), when the sample information detection unit 1 or 3 is attached to the finger 91 of the sample, the tissue (skin, fat) on the surface of the sample finger Etc.) rises and enters the first cavity 13, whereby the tissue may interfere with the pressure-sensitive element 24 functioning as the first sensor 14. If the diameter of the first opening 12 is too large, the first cavity 13 is closed when the sample information detection units 1 and 3 are attached so as to be in close contact with the three-dimensional shape of the finger 91 of the sample. May be difficult to form. In addition, when the height of the first cavity 13 is constant, the volume of the first cavity 13 increases as the diameter of the first opening 12 of the first cavity 13 increases, and the strength of the pulsation signal is constant. In this case, since the volume of the first cavity 13 is increased, the vibration caused by the pulsation signal of the blood vessel is attenuated, so that the intensity of the signal detected by the pressure-sensitive element 24 functioning as the first sensor 14 is reduced. There is a fear. If the diameter of the first opening 12 is too wide, the pulsation signal of the blood vessel can be detected even when the sample information detection units 1 and 3 do not exist directly above the blood vessel. There is a risk that the directivity of the pressure-sensitive element 24 functioning as will decrease.

  For this reason, the aperture of the first opening 12 is usually 3 mm or more, preferably 6 mm or more, and is usually 10 mm or less, preferably 8 mm or less. When the lower limit of the diameter of the first opening 12 is larger than the value in the above range, the detected pulsation signal becomes strong, and the first position is at a position where vibration from the blood vessel can be detected when it is attached to the finger 91 of the specimen. Since it becomes easy to make the opening part 12 closely_contact | adhered, it is preferable. Since the upper limit of the diameter of the first opening 12 is smaller than the value in the above range, the influence of the specimen entering the first opening 12 is suppressed, the decrease in sensitivity due to the increase in the volume of the first cavity 13 is prevented, and the first This is preferable because the directivity of the pressure-sensitive element 24 functioning as the sensor 14 can be provided.

  In addition, when the specimen information detection unit 1 or 3 of the present invention is attached to the finger 91 of the specimen and detects a pulsation signal of a blood vessel existing on the finger 91, the first cavity 13 forms a closed cavity to pulsate. From the viewpoint of detecting the sex signal with high sensitivity, the diameter of the first opening 12 is preferably at least half the finger span and not more than three-quarters the finger span.

(First cavity)
2 (a) and 2 (b), the first cavity 13 communicates with the first opening 12, and the first opening 12 is opposed to the belly portion 92 of the finger 91 by hand. It is a space structure that is closed while holding the housing parts 11 and 21, and is formed in the housing parts 11 and 21. The closed space structure formed by the first cavity 13 in this way is also referred to as “Closed Cavity”. Inside the first cavity 13, a pressure sensitive element 24 that functions as the first sensor 14 is provided.

(First light source)
As shown in FIGS. 20A and 20B, the first light source 17 is provided in the casing portions 11 and 21 and transmits an optical signal toward the finger of the hand that holds the casing portions 11 and 21. It is what happens. The first light source 17 is preferably a light supply source for supplying an intermittent optical signal, and for example, a laser diode (LD) or an LED (Light Emitting Diode) can be used. The wavelength of the light emitted from the first light source is not particularly limited as long as it can detect a pulsating signal as a photointerrupter. However, the wavelength is 940 nm because it is easily available or hardly affected by disturbance due to natural light. The light is preferably emitted.

As shown in FIG. 4, the first light source 17 is provided in the vicinity of the front wall portion inside the housing portions 11 and 21 and is provided so as to emit an optical signal toward the outside. The optical signal emitted from the first light source 17 is transmitted through a light transmitting portion 23 described later, hits the finger 91 of the hand that holds the housing portions 11 and 21, and the light signal reflected by the finger 91 passes through the light transmitting portion. Then, as detected by a first sensor 14 to be described later, the light signal emitted from the first light source 17 is not perpendicular to the end surfaces of the housing parts 11 and 21 but is at a predetermined angle. It is preferably provided so as to emit a signal.
The first light source 17 functions as a photo interrupter (also referred to as a photo reflector) together with a light transmitting portion 23 described later and a light receiving element 18 that functions as the first sensor 14.

(Light transmission part)
As shown in FIG. 20A and FIG. 20B, the light transmission portion 23 is provided at a portion of the casing portions 11 and 21 that should face the fingers of the hand that holds the casing portions 11 and 21. It is made of a transmissive material that can transmit an optical signal from the first light source 17. For example, glass or synthetic resin (plastic) that can transmit an optical signal from the first light source 17 can be suitably used as the material used for the light transmission portion 23. Among these, it is particularly preferable to use a material that can selectively transmit light having the wavelength of the optical signal from the first light source 17. Moreover, it is preferable to use a non-processed surface for the light transmitting portion 23.

  As shown in FIG. 4, the light transmitting portion 23 is provided on the front wall portion of the casing portions 11 and 21, and the finger 91 of the hand that holds the casing portions 11 and 21 is provided on the casing portions 11 and 21. When facing the light transmission part 23, the light signal from the first light source 17 passes through the light transmission part 23 and hits the finger 91, and the light signal reflected by hitting the finger 91 passes through the light transmission part 23 and passes through the first sensor. 14 is preferably configured to be detected. The thickness t of the light transmitting portion 23 needs to be matched with the set surface depth of the photo interrupter configured by the first light source 17, the light transmitting portion 23, and the light receiving element 18 functioning as the first sensor 14. When the refractive index of the material constituting the light transmitting portion 23 is n, the necessary thickness t of the material must be multiplied by n.

(First sensor)
As shown in FIG. 1A, FIG. 1B, FIG. 20A, and FIG. 20B, the first sensor 14 is provided in the casing portions 11 and 21, and the casing portions 11 and 21 are provided. The pulsation signal of the blood vessel in the finger of the hand holding the finger is detected and output as a pulsation signal (pulse wave signal).

  As shown in FIGS. 1 (a) and 1 (b), a first opening 12 is formed in the casings 11 and 21 of the sample information detection units 1 and 3, and the first cavity 13 is a casing. When formed in the portion 11, it is preferable that a pressure sensitive element 24 is provided as the first sensor 14. At this time, the pressure-sensitive element 24 functioning as the first sensor 14 transmits the pulsation signal of the blood vessel in the finger inputted through the first opening 12 and the pressure information propagating in the first cavity 13 due to the pulsation signal. Detect as.

  As shown in FIGS. 20A and 20B, when the first light source 17 and the light transmitting portion 23 are provided in the casing portions 11 and 21 of the specimen information detection units 8 and 9, A light receiving element 18 is preferably provided as the first sensor 14. At this time, the light receiving element 18 functioning as the first sensor 14 receives the pulsation signal of the blood vessel in the finger, and receives the optical signal reflected by the light signal from the first light source 17 due to the pulsation signal. To detect.

  Note that, even if a pulsation signal is detected using the pressure-sensitive element 24 as the first sensor 14 or a pulsation signal is detected using the light receiving element 18, a pulsation signal described later is used. The signal processing for can be performed in the same manner.

  When a pressure-sensitive element is provided as the first sensor 14, it is not particularly limited as long as it can detect a pulsation signal of a blood vessel in a finger, but air generated by vibration of a skin portion of a finger of a specimen caused by blood vessel pulsation A microphone that electrically detects the vibration (sound pressure information) or a pressure-sensitive element such as a piezoelectric element can be preferably used. Among the microphones, a condenser microphone is preferable in terms of directivity, S / N ratio, and sensitivity, and an ECM (electret condenser microphone; hereinafter, also simply referred to as “ECM”) can be suitably used. In addition, a MEMS ECM (hereinafter, also referred to as “MEMS-ECM”), which is an ECM manufactured using a microelectromechanical system (MEMS) technique, can be preferably used. As the piezoelectric element, a PZT piezoelectric element using lead zirconate titanate (also referred to as PZT) can be suitably used as a ceramic exhibiting high piezoelectricity.

  Here, as shown in FIG. 3, the PZT element has a multi-layer structure of lead zirconate and can be used in a closed cavity situation similar to ECM on the premise of the d33 mode. Since the impedance is high, impedance conversion can be performed across 0V with a depletion-type junction FET as shown in FIG. 3 as in the case of the microphone diaphragm, and it can be handled in the same way as ECM. Since the PZT element is small, it has a feature that it can be easily mounted in the first cavity 13. Further, the PZT element has a feature that a band is wide.

  When a light receiving element is provided as the first sensor 14, a blood vessel pulsation signal in the finger can be detected by receiving an optical signal reflected by the light signal from the first light source due to the pulsation signal and reflected by the finger. Although there is no particular limitation as long as it is present, a photodiode can be preferably used. As shown in FIG. 4, a pulsating signal can be detected by using the principle of a photo interrupter (also referred to as a photo reflector) by the first light source 17, the light transmitting portion 23, and the light receiving element 18.

(Guide groove)
As shown in FIG. 1A, FIG. 1B, FIG. 20A, and FIG. 20B, the guide groove 15 guides the finger 91 when the casings 11 and 21 are grasped by hand. It is a site | part which is, and is a site | part currently formed in groove shape so that the front wall part of a housing | casing part may be dented inside. The guide groove 15 draws an arc having a semicircular or elliptical cross section so that the finger 91 can be a guide for stably holding the casing when the casings 11 and 21 are grasped by hand. Thus, it is preferable that the casing portions 11 and 21 are formed so as to surround the circumferential direction. Further, the length in the circumferential direction is preferably at least the length from the fingertip of the person's finger to the first joint, and more preferably about the length of the person's finger. Further, the depth of the guide groove 15 is preferably provided from the surface of the housing part to a depth of about ¼ to ½ in the finger cross-sectional direction. In the guide groove 15, the first opening 12 or the light transmitting portion 23 is formed, so that the finger 91 of the hand is along the guide groove 15 or the finger 91 of the hand is aligned with the guide groove, In the vicinity of the end 22 of the guide groove 15 so that the first opening 12 or the light transmitting portion 23 is formed at a portion to be opposed to the abdomen 92 of the finger 91 when the housing parts 11 and 21 are gripped. It is preferable that the first opening 12 or the light transmission part 23 is formed.

  In the sample information detection units 1, 3, 8, and 9 according to the first embodiment of the present invention, the guide grooves 15 are formed in the housing portions 11 and 21, so that the fingers 91 are along the guide grooves 15. The body parts 11 and 21 are gripped by hand, and the specimen information detection unit can be stably held.

(Polarity notification unit)
The polarity notification unit 25 receives a signal from the polarity determination means due to the output from the first sensor 14 and notifies a change in polarity (FIGS. 23 and 24).

  The polarity notification unit 25 is configured to determine the polarity of the waveform of the pulsation signal detected by the first sensor 14 by the polarity determination unit, and to notify the change in polarity due to the output from the polarity determination unit. When the polarity detected by the first sensor changes, this is notified. In addition, the polarity determination part 102 in the signal processing part 101 mentioned later functions as a presence determination means.

  The notification means of the polarity notification section 25 may be, for example, a display by turning on an LED or a notification using visual information on a liquid crystal screen, and a beep sound by a buzzer or a sounding means such as sounding by a speaker. Although the notification used may be sufficient and the notification using the vibration by a vibrator may be sufficient, it is preferable that it is a notification means different from the grip strength notification part mentioned later.

(Grip strength sensor)
As shown in FIGS. 1A, 1 </ b> B, 20 </ b> A, and 20 </ b> B, the casing portions 11 and 21 include the first opening 12 or the peripheral portion of the light transmission portion 23. In addition, a grip strength sensor 16 that detects the grip strength of the hand as a pressing force (pressing information) and outputs it as a pressing signal is provided, and the grip of the hand is caused by the output from the grip strength sensor 16. It is preferable to provide a grip strength informing unit 26 for informing the strength of the hand (FIGS. 23 and 24).

  The grip strength sensor 16 detects the grip strength of the hand of the specimen that grips the casings 11 and 21 as pressing information applied to the grip strength sensor 16 due to the grip strength of the hand. It is output as a strength signal.

  As the grip strength sensor 16, a circular sheet-like pressure sensor can be suitably used. As shown in FIGS. 1 and 2, the first opening 12 is formed in the guide groove 15 formed in the front wall portion of the housing portions 11, 21, and the first cavity 13 is formed around the first opening 12. It is preferable to take a shape in which a circular sheet-like pressure sensor having a hole at the center is arranged in accordance with the first opening 12 so as not to prevent communication with the outside. When the fingertip touches the sheet-shaped pressure sensor, the first cavity 13 creates a closed space with the fingertip facing the first opening 12, and the pressure applied to the fingertip at that time is pressed to be applied to the sheet-shaped pressure sensor. The pressure information (pressing information) is detected by a sheet-like pressure sensor as the grip strength.

  The grip strength sensor 16 may be a tube of a tire made of a hollow, soft rubber type connected to a semiconductor pressure sensor, instead of the above-described sheet sensor.

(Grip strength notification part)
The grip strength notification unit 26 notifies the grip strength of the hand based on the output from the grip strength sensor 16 (FIGS. 23 and 24).

  The grip strength notification unit 26 can be configured to notify the numerical value of the grip strength (pressing force) detected by the grip strength sensor. Alternatively, a predetermined pressing force may be set, and when the pressing force detected by the grip strength sensor becomes a predetermined value set in advance, it may be configured to notify that fact. In this case, for example, the pressure information detection unit 103 of the signal processing unit 101 to be described later controls the pressing state as the pressure information detection unit, so that it is appropriate to hold the specimen information detection units 1, 3, 8, and 9 in advance by hand. By obtaining a sufficient grip strength, it is possible to notify when the pressing force detected by the grip strength sensor 16 reaches an appropriate pressing force.

  The notification means of the grip strength notification unit 26 may be, for example, a display by turning on an LED or a notification using visual information on a liquid crystal screen, such as a beep sound by a buzzer or a sound generated by a speaker. Although notification using a means may be sufficient and notification using vibration by a vibrator may be sufficient, it is preferred that it is a notification means different from the above-mentioned polarity information section 25.

(Signal processing part)
The signal processing unit 101 detects a pulsation signal (pulse wave signal) detected by the first sensor 14 and a signal (pressing force) about the pressing force regarding the grip strength of the hand detected by the grip strength sensor 16. Signal). The signal processing unit 101 includes a polarity determination unit 102, a pressing information detection unit 103, and a pressing optimization unit 104 as electric circuits (FIGS. 23 and 24).

  The polarity determination unit 102 determines the polarity of the pulse wave by processing the pulse wave signal detected by the first sensor 14, and displays the determination result. Alternatively, the polarity determination unit 102 may display that polarity reversal has occurred when polarity reversal is detected.

  The pressing information detection unit 103 performs processing on the pulse wave signal detected by the first sensor 14 and the pressing signal detected by the grip strength sensor, so that when the pulse wave polarity changes, the grip strength sensor The value of the pressing force detected by is detected.

  The press optimizing unit 104 processes the pulse wave signal detected by the first sensor 14 and the press signal detected by the grip strength sensor, thereby optimizing the press force that is the grip strength of the hand. To do.

<About the specimen information detection unit>
The sample information detection units 1 and 3 according to the first embodiment of the present invention are configured as described above, and are abdominal portions that serve as contact portions of the finger 91 of the hand of the sample that holds the housing portions 11 and 12. By closely contacting the first opening 12 to 92, a spatial structure (closed cavity) in which the first cavity 13 is closed is formed. In this state, the pressure-sensitive element 24 functioning as the first sensor 14 of the sample information detection unit 1, 3 generates a pulsation signal of a blood vessel existing in the vicinity of the attachment site of the sample information detection unit 1, 3 on the sample finger 91. The blood pressure pulsation signal in the specimen is detected by receiving the pressure information.

  Alternatively, the sample information detection units 8 and 9 according to the first embodiment of the present invention are configured as described above, and serve as contact portions of the finger 91 of the sample hand holding the housing portions 11 and 12. The light transmission part 23 is brought into close contact with the abdomen 92. In this state, the optical signal from the first light source 17 is transmitted through the light transmitting portion 23 and hits the finger 91, and the optical signal reflected by the finger 91 is transmitted through the light transmitting portion 23, and the sample information detecting units 8 and 9 The light receiving element 18 functioning as the first sensor 14 causes the light signal from the first light source 17 to be generated by the finger 91 due to the pulsation signal of the blood vessel existing in the vicinity of the mounting site of the sample information detection units 8 and 9 on the sample finger 91. By receiving the light signal reflected by the light, the pulsation signal of the blood vessel in the specimen is detected.

<About closed cavity>
In the sample information detection units 1 and 3 according to the present invention, the first opening 12 having a diameter of 3 mm to 8 mm is formed in a portion of the casing that should face the finger 91 of the hand holding the casings 11 and 21. In addition, the first opening 12 communicates with the first opening 12, and the first opening 12 is opposed to the finger 91 to form a space structure (closed cavity) that is closed in a state where the hands 11 and 21 are gripped by the hand. The first cavity 13 is formed in the housing parts 11 and 21, and the pulsation signal of the blood vessel in the finger 91 input through the first opening 12 is used as pressure information propagating in the first cavity due to the pulsation signal. It can comprise so that it may detect with the 1st sensor provided in the housing | casing parts 11 and 21. FIG.

  When detecting a pulsation signal of a blood vessel in a specimen, it is possible to capture vibration originating from the movement of the heart from anywhere on the specimen finger 91. For example, a sensor (pressure sensitive sensor) that can sense pressure such as a microphone or a piezoelectric element. It is possible to try to detect vibration in the open state by placing the element) at an appropriate part of the finger. However, the amplitude of the movement due to the pulsation of the heart and blood vessels is extremely small, and even if the pressure sensitive element is arranged near the finger 91 of the specimen, the vibration originating from the movement of the heart is caused when the pressure sensitive element is open. It is difficult to detect.

  In order to detect the pulsating signal of the specimen, for example, a method of pressing the pressure sensitive element directly on the skin of the specimen is conceivable. However, a desired signal cannot be obtained satisfactorily even if, for example, a microphone is pressed directly against the specimen as a pressure sensitive element. For example, in an ECM with an air hole diameter of 2 mm, a signal can be detected only when the air hole comes right above the blood vessel. On the other hand, in MEMS-ECM, the signal can hardly be detected because the diameter of the air hole (sound hole) is smaller than that of the blood vessel. This is because, when a closed cavity having a first opening and a first cavity is not provided between the specimen and the sensor, it is directly below the pressure information capturing part (air hole, sound hole) of the ECM or MEMS-ECM. This is considered to be because the pulsation signal of the blood vessel at a position outside the pressure information capturing portion cannot be detected.

  In the sample information processing unit 1, the first opening 12 and the first cavity 13 are formed, the first sensor mounting portion 11 is provided, and the finger 91 and the first opening are held in a state where the housing is gripped by the hand. A closed cavity can be formed by making the part 12 face and abut. Thereby, according to the present sample information processing unit 1, it is possible to detect a pulsation signal of a blood vessel within the range of the first opening 12.

<Photo interrupter>
As shown in FIG. 4, the sample information detection units 8 and 9 of the present invention include a first light source 17 that generates an optical signal toward a finger 91 of a hand that holds the casings 11 and 21, and the casing 11 , 21 is provided with a light transmitting portion 23 at a portion of the housing portion that should face the finger 91 of the hand holding the light 21, and the light signal from the first light source 17 is transmitted through the light transmitting portion 23 and reflected by hitting the finger 91. A light receiving element 18 for receiving a signal is provided, and a pulsating signal can be detected using the principle of a photo interrupter.

  For example, the first light source 17 is an LED that emits light having a wavelength of 940 nm. Light is emitted from the first light source 17 toward the abdomen 92 of the finger 91, and this light is reflected on the skin of the finger 91 to reflect the light. Light is detected by the light receiving element 18. The reflected light detected by the light receiving element 18 is affected by the vibration of the skin surface caused by the pulsation of the blood vessels of the finger 91 when reflected by the skin of the finger 91. By closely contacting, the pulse wave from the fingertip can be detected as a pulsation signal of the blood vessel. In this case, at least the first light source is provided at a portion of the casing portions 11 and 12 that should face the finger 91 of the hand that grips the casing portions 11 and 21 on the front wall portion constituting the outer surface of the casing portions 11 and 21. The light transmission part 23 made of a transmissive material capable of transmitting the optical signal from the first light source 17 is provided in a portion where the light emitted from the light 17 passes through and hits the finger 91 and the reflected light is transmitted. Is preferred. Moreover, when detecting the pulsation signal with light using the light receiving element 18 as the first sensor 14, it is preferable to cover the periphery with a light shielding material so that light such as room lighting does not enter.

  FIG. 5 shows the response waveform of the pulse wave detected from the fingertip using the principle of such a photo interrupter. In FIG. 5, the pulse wave is detected with the room light on in the left third region of the waveform, and the pulse wave is detected with the room light off in the right third region. Detected. As apparent from FIG. 5, in the left one-third region, the 50 Hz component of the room illumination is detected by the light receiving element 18 and appears as noise in the waveform of the pulse wave. It can be seen that the sensor needs to be shielded when detecting the signal. For this reason, the influence of disturbances such as illumination can be suppressed by using a wavelength-selective material capable of transmitting light having the wavelength of the optical signal from the first light source 17 in the light transmitting portion 23 shown in FIG. preferable.

<Grip position of body information detection unit>
The sample to which the sample information detection unit 1, 3, 8, 9 is applied is preferably used by humans, but can detect a pulsating signal of a blood vessel while holding the casing with the sample finger 91 If it is, it will not restrict | limit in particular, It can use also for an animal other than a person or a person.

  Conventionally, a pressure sensor is disposed on the abdomen of a fingertip of a specimen, and a pulsating signal is detected from a capillary vessel existing at the fingertip. According to the study of the present inventor, when pressure-sensitive inhibition is brought into contact with the contact portion with the skin portion corresponding to the joint portion of the finger, arterial blood vessels (hereinafter simply referred to as “blood vessels”) in the joint portion instead of the capillary It was also found that it can detect the heartbeat itself. The position of the skin portion corresponding to the finger joint is a position where the pulsation of the blood vessel can be detected and the blood vessel can be defined, and the obtained pulse wave signal is also considerably larger than the capillary of the fingertip. For this reason, among the abdomen portions 92 of the finger 91, the first opening 12 is brought into contact with the contact portion with the skin portion corresponding to the joint portion of the finger, so that it is relatively larger than in the case of the capillary at the fingertip. A stable pulse wave can be obtained.

  In the specimen information detection units 1 and 3 of the present invention, when the first opening 12 is formed using a pressure-sensitive element as the first light source, the pressure in the first cavity 13 that becomes a closed space on the basis of the closed cavity principle. In order to capture the change, a pulsatile signal can be detected as a large pressure change by entering a two-dimensional blood vessel in this footprint. It is not always necessary to place the blood vessel at the center of the first opening 12. By placing the first opening 12 at the position where the blood vessel exists, the finger 91 or the sample information detection unit is moved as little as possible. However, the pulsating signal can be detected.

  Of course, in the case of a capillary vessel on the opposite side of the nail, the influence of moving the finger 91 is smaller, but the present inventor has focused on the magnitude of the signal from the blood vessel near the joint. In addition, for long-term measurements in capillaries, the reason is not clear, but the pulse wave signals from the blood vessels near the joint are more stable than fluctuations in the amplitude of the pulse wave signals picking up the capillaries. Yes. Taking a pulsating signal from the fingertip may assume a relatively long time, and a contact portion with the skin portion corresponding to the joint portion of the finger can be preferably used.

  That is, when the first opening 12 is formed using a pressure-sensitive element as the first light source, when holding the casings 11 and 21 of the sample information detection units 1 and 3 with the hand, It is preferable to hold the housing parts 11 and 21 with the hand so that the corresponding skin part and the first opening 12 are in contact with each other. From the viewpoint of ease of gripping and ease of applying force, the first finger 91 It is particularly preferable that the housing portions 11 and 21 are gripped by hand so that the skin portion corresponding to the joint portion 94 and the first opening 12 come into contact with each other. In other words, the first opening 12 formed in the guide groove, the first cavity 13 formed together with the first opening 12, and the pressure sensitive functioning as the first sensor 14 provided in the first cavity 13. The position of the element 24 is a portion where the first opening 12 comes into contact with the skin portion corresponding to the joint portion of the finger 91 when the housing portions 11 and 21 are held by the hand so as to fit the guide groove 15. It is preferable that the first opening 12 is a part that comes into contact with the skin part corresponding to the first joint part of the finger 91. In this case, it can be realized by providing the first opening 12 by taking a length from the end portion 22 of the guide groove 15 to the length from the human fingertip to the first joint.

  When the first opening 12 of the sample information detection unit 1, 3 is a part that comes into contact with the skin portion corresponding to the joint portion of the finger 91, at least the end of the first opening 12 of the sample information detection unit 1, 3. However, it is preferable that the first opening 12 of the specimen information detection unit 1 or 3 is located above the position of the joint of the finger joint. .

  If you want to further reduce the influence of body motion on the pulsation signal, use multiple fingers to detect the pulsation signal and take the majority logic among them or select the one with the best condition It is preferable to use means together.

<Other configuration>
In addition to the above configuration, the sample information detection units 1, 3, 8, and 9 preferably further include the following configuration.

(Sample detection sensor and sample notification unit)
The sample information detection units 1, 3, 8, and 9 preferably include the sample detection sensor 27 and the sample notification unit 28 in the casing units 11 and 21 (FIGS. 23 and 24).

  The specimen detection sensor 27 is a proximity sensor that senses that a person has approached the specimen information detection units 1, 3, 8, and 9, especially that a hand has approached, and outputs the signal to the signal processing unit 101. As such a proximity sensor, it is preferable to use a sensor having a large area so as to operate when a hand is approached from all directions of the sample information detection units 1, 3, 8 and 9. As the sample detection sensor 27, for example, a metal is affixed to the inside of the casing parts 11 and 21, and the metal is electrically grounded. Further, at least a cylinder or an egg-shaped outside of the casing parts 11 and 21 is provided. By attaching metal foils connected to each other at multiple locations, the capacitance between the two metals inside and outside can be monitored to detect that the hand has approached the change. can do. Alternatively, by arranging a plurality of pyroelectric elements (pyrosensors) for temperature measurement around the casing parts 11 and 21, infrared rays can be detected when a hand is brought close to sense that the hand is approaching. Good. Such a pyroelectric element can be used in combination with an element for detecting body temperature that uses infrared rays.

  The sample notification unit 28 is an output from the sample detection sensor 27 when the sample detection sensor 27 detects that a person has approached the sample information detection units 1, 3, 8, and 9, especially that a hand has approached. This is a part that receives a signal from the signal processing unit 101 and informs a person of the position of the housing unit. The sample notification unit 28 can notify a person by light or sound, but in particular, it is possible to notify the position by emitting light entirely by the LEDs provided in the casing units 11 and 21. preferable. As an example, as shown in FIG. 6, in the casing portion 21 configured as an egg-shaped member, an LED 19 that emits light toward the upper portion of the casing portion 21 on the circumference near the center in the long side direction, and the casing The LEDs 20 that emit light toward the lower part of the body part 21 can be arranged at equal intervals. With this configuration, when a person is detected by the sample detection sensor 27, the LED 19 and the LED 20 function as the sample notification unit 28 due to the output from the sample detection sensor 27 via the signal processing unit 101. As a result, the entire housing portion 21 can emit light.

  By providing the casing 11 and 21 with the sample detection sensor 27 and the sample notification unit 28, the sample information detection units 1, 3, 8, and 9 are about to be used while feeling some change during sleep, for example. At this time, the sample detection sensor 27 detects that the hand has approached the housing units 11 and 21 by reaching the sample information detection units 1, 3, 8, and 9, and the LED serving as the sample notification unit 28. The sample information detection unit can be used promptly by notifying the position of the sample information detection unit by turning on the light for a certain period of time.

(Memory means)
In the sample information detection units 1, 3, 8, and 9, it is preferable that a storage unit 29 is provided in the housing portions 11 and 21 (FIGS. 23 and 24). The storage means 29 stores the measurement result (measurement information) by the first sensor 14 or the grip strength sensor 16 through the signal processing unit 101 by transferring information from the signal processing unit 101. is there. Information obtained by the clock 42, the GPS processing circuit 44, the body temperature detecting means 45, and the outside air temperature detecting means 46 may be stored.
The storage unit 29 is not particularly limited as long as it is a recording device that stores measurement results, but a flash memory is preferably used because it is small and easy to incorporate.

(Clock and GPS)
The sample information detection units 1, 3, 8, and 9 include a clock 42, a GPS (Global Positioning System) antenna 43, and a GPS processing circuit 44 in the housing units 11 and 21. It is preferable (FIGS. 23 and 24). The GPS antenna 43 and the GPS processing circuit 44 are collectively referred to as GPS.

The clock 42 is not particularly limited as long as it can acquire time, but among these, a radio clock that can receive a date and time information signal transmitted from a standard radio wave transmitting station and set the time is preferable. The date and time information signal acquired by the clock 42 is transmitted to the signal processing unit 101.
The position information signals acquired by the GPS antenna 43 and the GPS processing circuit 44 are transmitted to the signal processing unit 101.

  The storage means 29 receives a signal from the signal processing unit 101 and stores the measurement result by the clock 42, the GPS antenna 43 and the GPS processing circuit 44 and the measurement result by the first sensor 14 in association with each other. Of course, in addition to the measurement results obtained by the first sensor 14, the measurement results such as the body temperature and the outside air temperature may be stored in association with each other.

  The sample information detection units 1, 3, 8, and 9 include the clock 42, the GPS antenna 43, and the GPS processing circuit 44, and thus have, for example, the sample information detection units 1, 3, 8, and 9. Even when traveling as it is, when data is acquired by the first sensor 14, the time and place where the data was acquired can be recorded in association with each other.

(Body temperature detection means and outside air temperature detection means)
The sample information detection units 1, 3, 8, and 9 include a body temperature detection unit 45 that detects the body temperature of the hand that holds the housing unit, and an outside air temperature detection unit 46 that detects the outside air temperature. It is preferable to provide a storage means 29 for storing the measurement results of the body temperature detection means 45 and the outside air temperature detection means 46 via the signal processing unit 101 (FIGS. 23 and 24).
The information signal related to the body temperature detected by the body temperature detecting means 45 and the information signal related to the outside air temperature detected by the outside air temperature detecting means 46 are transmitted to the signal processing unit 101.

The outside air temperature detection means 46 and the body temperature detection means 45 are not particularly limited, and conventional temperature sensors can be used as appropriate.
As the body temperature detecting means 45, for example, a thermistor or an infrared sensor using pyroelectricity can be used. When gripping the casings 11 and 21, the thermistor is sandwiched between fingers, or even if the finger is not touching, the infrared rays coming out from the fingertip are detected by an infrared sensor, so that the hand portion such as the fingertip Body temperature can be measured. As compared with the case where the body temperature is detected from the armpit or anus using a normal thermistor or the like, it is preferable to perform comparison / calibration in advance when the body temperature is detected from the hand portion such as the fingertip as described above.

  Since the sample information detection units 1 and 3 include the body temperature detection unit 45 and the outside air temperature detection unit 46, when the data is acquired by the first sensor 14, the data is acquired via the signal processing unit 101. The body temperature and the outside air temperature can be recorded in association with each other.

(Storage battery and cradle)
The specimen information detection units 1, 3, 8, and 9 are preferably provided with a storage battery 47 in the casing portions 11 and 21, and are driven by electric power supplied from the storage battery 47 (FIGS. 23 and 24). Furthermore, the sample information detection units 1, 3, 8, and 9 include coils in the housing portions 11 and 21, and can hold the housing portions 11 and 21 as shown in FIG. It is preferable that the battery can be charged in a non-contact manner by being placed on the cradle 2.

  The cradle 2 is mounted with the casings 11 and 21 of the sample information detection units 1, 3, 8 and 9 and the electrodes in contact or non-contact state, and reads measurement signals from the casings 11 and 21. It preferably has a power feeding function.

  When the specimen information detection unit 1, 3, 8, 9 does not detect a pulsation signal, the storage battery 47 is supplied by power supply from the cradle 2 by placing the housing portions 11, 21 on the cradle 2. Can be charged. Furthermore, the data stored in the storage means 29 is sent to the cradle 2 from the specimen information detection unit 1, 3, 8, 9 via the cradle 2 in a contact state or a non-contact state, and the cradle 2 sends an external computer. To be transmitted.

[1-2. Functional configuration of sample information detection unit according to first embodiment]
Hereinafter, an example of the functional configuration of the sample information detection units 1, 3, 8, and 9 according to the first embodiment of the present invention will be described.

(In the case of a specimen information detection unit provided with a pressure sensitive element)
When the sample information detection units 1 and 3 according to the first embodiment of the present invention are functionally represented, the sample information detection units 1 and 3 function as the first sensor 14 as shown in FIG. , Grip strength sensor 16, polarity notification unit 25, grip strength notification unit 26, sample detection sensor 27, sample notification unit 28, storage unit 29, clock 42, GPS antenna 43, GPS processing circuit 44, body temperature detection unit 45, an outside air temperature detecting means 46, a storage battery 47, and a signal processing unit 101. The signal processing unit 101 includes a polarity determination unit 102, a pressing information detection unit 103, and a pressing optimization unit 104.

The pressure-sensitive element 24 functioning as the first sensor 14 detects the pulsation wave (pulsation signal) of the blood vessel as pressure information resulting from the pulsation signal, and the grip strength sensor 16 causes the grip strength. Signals detected by the pressure-sensitive element 24 and the grip strength sensor 16 that detect the pressing information and function as the first sensor 14 are sent to the signal processing unit 101, and the polarity determination unit 102, the pressing information detection unit 103, and the pressing information The optimization unit 104 is configured to process the signal.
The signal processing unit 101 receives signals from the sample detection sensor 27, the clock 42, the GPS processing circuit 44, the body temperature detection unit 45, and the outside air temperature detection unit 46, processes these signals, and outputs the polarity notification unit 25, The grip strength notifying unit 26 and the sample notifying unit 28 are operated, and the measurement information stored in the storage unit 29 is transferred.
The storage means 29 transfers measurement information to the outside via the cradle, and the storage battery can be charged via the cradle 2.

(In the case of a specimen information detection unit provided with a light receiving element)
When functionally representing the specimen information detection units 8 and 9 according to the first embodiment of the present invention, as shown in FIG. 24, the specimen information detection units 8 and 9 include the light receiving element 18 that functions as the first sensor 14, Grip strength sensor 16, first light source 17, polarity notification unit 25, grip strength notification unit 26, sample detection sensor 27, sample notification unit 28, storage means 29, clock 42, GPS antenna 43, GPS processing circuit 44 , Body temperature detection means 45, outside air temperature detection means 46, storage battery 47, and signal processing unit 101. The signal processing unit 101 includes a polarity determination unit 102, a press information detection unit 103, and a press optimization unit 104. .

The light-receiving element 18 functioning as the first sensor 14 detects a pulsation wave (pulsation signal) of the blood vessel as an optical signal resulting from the pulsation signal, and the grip strength sensor 16 presses due to the grip strength. Signals detected by the light receiving element 18 and the grip strength sensor 16 that detect information and function as the first sensor 14 are sent to the signal processing unit 101, and the polarity determination unit 102, the press information detection unit 103, and the press optimization The unit 104 is configured to process the signal.
The signal processing unit 101 receives signals from the sample detection sensor 27, the clock 42, the GPS processing circuit 44, the body temperature detection unit 45, and the outside air temperature detection unit 46, processes these signals, and outputs the first light source 17, The polarity notification unit 25, the grip strength notification unit 26, and the sample notification unit 28 are operated, and the measurement information stored in the storage unit 29 is transferred.
The storage means 29 transfers measurement information to the outside via the cradle, and the storage battery can be charged via the cradle 2.

[1-3. Operation of the specimen information detection unit according to the first embodiment]
Below, an example of operation | movement of the sample information detection unit 1, 3, 8, 9 concerning 1st embodiment of this invention is demonstrated.

<Detection of pulsation signal and pressing force>
(In the case of a specimen information detection unit provided with a pressure sensitive element)
A first opening 12 is formed in the casing portions 11 and 21 of the specimen information detection units 1 and 3, a first cavity 13 is formed in the casing portion 11, and a pressure sensitive element 24 is used as the first sensor 14. The operation when it is provided will be described.

  As shown in FIG. 2 (a), the casing unit 11 is configured such that the fingertip is pressed so that the first opening 12 is in contact with the first joint from the tip of the fingertip of the sample finger 91. 21 is held by hand so that the first cavity 13 forms a closed space structure (closed cavity). In this state, the pressure sensor 24 as the first sensor 14 provided in the first opening 12 generates a pulse wave (pulsation signal) in a fine blood vessel, a capillary blood vessel at a fingertip, or an arterial blood vessel existing in a joint portion. Detected as pressure information resulting from the pulsation signal. Further, the grip strength sensor 16 provided in the peripheral portion of the first opening 12 detects the grip strength of the hand as a pressing force (press signal) for pressing the grip strength sensor 16 with a finger. At this time, the specimen information detection units 1 and 3 are held by holding the casings 11 and 21 with one hand (left hand) and attaching the finger of the other hand (right hand) to the finger of the left hand. May be.

(In the case of a specimen information detection unit provided with a light receiving element)
The operation in the case where the first light source 17 and the light transmission part 23 are provided in the casing parts 11 and 21 of the sample information detection units 8 and 9 and the light receiving element 18 is provided as the first sensor 14 will be described.

  As shown in FIG. 4, the finger of the hand grasping the housing parts 11 and 21 so that the optical signal emitted from the first light source 17 is applied between the tip of the fingertip of the specimen finger 91 and the first joint. The casings 11 and 21 are gripped by a hand such that 91 is opposed to the light transmission part 23 and a fingertip is pressed against the light transmission part 23. In this state, an optical signal from the first light source 17 passes through the light transmitting portion 23 and hits the finger 91, and an optical signal reflected by hitting the finger 91 passes through the light transmitting portion 23 and is received by the light receiving element 18 as the first sensor 14. Detected. As a result, the first sensor 14 causes a pulse wave (pulsation signal) in a fine blood vessel, a capillary blood vessel at the fingertip of the finger 91, or an arterial blood vessel in the joint portion to be generated from the first light source 17 due to the pulsation signal. Is detected as the intensity of the optical signal by receiving the optical signal reflected by the finger 91 and reflected. Further, as shown in FIGS. 20A and 20B, the grip strength sensor 16 provided on the periphery of the light transmitting portion 23 is used to determine the grip strength of the hand with a finger. This is detected as a pressing force (pressing signal) for pressing 16. At this time, the specimen information detection units 8 and 9 are held by holding the casings 11 and 21 with one hand (left hand) and attaching the finger of the other hand (right hand) to the finger of the left hand. May be.

<Pressing state control>
Next, in order to determine the pressure with which the first opening or the light transmission part 23 is pressed with a finger, that is, the grip strength, when holding the casings 11 and 21 of the specimen information detection units 1, 3, 8 and 9 with a hand. The control of the pressing state will be described.

  In the following description, the first opening 12 is formed in the casing portions 11 and 21 of the sample information detection units 1 and 3, and the first cavity 13 is formed in the casing portions 11 and 21. Although the case where the pressure-sensitive element 24 is provided as one sensor 14 will be described, the first light source 17 and the light transmission part 23 are provided in the casing parts 11 and 21 of the specimen information detection units 8 and 9, and the first sensor 14 is provided. Even when the light receiving element 18 is provided as the sensor 14, signal processing can be performed in the same manner.

  When one hand (here, the finger of the left hand) is brought into contact with the first opening 12 and a force of gradually pressing is applied, the detected pulse wave has a horizontal axis of 1.0 as shown in FIG. From the waveform in which the peak (vertex) of the pulse wave appears in the negative region, such as the waveform on the left side up to about 4.0, the peak of the pulse wave is positive, as in the waveform on the right side after about 4.0 on the horizontal axis. Like the waveform appearing in the region, the peak changes so as to reverse, that is, the pulse wave has a change in polarity. 7 is a velocity pulse wave. Although the reason for the occurrence of such a phenomenon is not necessarily clear, this phenomenon is used for pressure detection by forming a closed cavity with the above-described PZT even when the ECM is used as the first sensor 14. Even in the case where the pulse wave is detected by forming a closed cavity having a diameter similar to the diameter of the first opening 12 according to the present invention, the same phenomenon can be confirmed. It can be considered that the closed cavity overlaps with some phenomenon of the living body, not the difference in elements. In this embodiment, as the pulsation signal, the polarity of the weaker pressure, that is, the left waveform in FIG. 7 is detected as the pulsation signal. It should be noted that the polarity of the stronger pressure, that is, the pulse wave of the right polarity in FIG. 7 is considered to be stronger against the disturbance, so the right waveform may be used as the pulsation signal.

  In view of the change in the polarity of the pulse wave due to the force pressing the first opening, in order to determine the polarity of the pulse wave in detecting the pulsation signal of the blood vessel, It is necessary to determine the grip strength. When the signal processing unit 101 as a grip strength determining unit for performing the processing for this purpose is functionally represented, it can be configured as shown in the block diagram of FIG. As shown in FIG. 8, the signal processing unit 101 includes amplifiers 111 and 112, a band pass filter 121, a low pass filter 122, an AD conversion unit 123, a peak hold 131, a bottom hold 134, window comparators 132 and 135, AGC 141, AD A conversion unit 142, a phase comparator 143, a low-pass filter 144, a VCO 145, a frequency divider 146, a timing generation unit 147, a sample hold 148, and a logic circuit 149 are provided. Furthermore, you may provide LED133, 136, 150, 151 for showing the detection result of a signal, or the parameter | index of control.

  The circuit shown in the block diagram of FIG. 8 includes a blood vessel pulsation signal that is a pulse wave signal detected by the first sensor 11 and a pressure that is a finger pressing force signal that is detected by the grip strength sensor. Two signals are input. Here, it is assumed that the pressing signal generates a voltage proportional to the pressing force applied to the grip strength sensor 16.

(Polarity judgment part)
The polarity determination unit 102 determines the polarity of the input pulse wave signal and displays the determination result. Alternatively, the polarity determination unit 102 may display that the polarity is reversed when the polarity reversal is detected. In the present embodiment, the polarity determination unit 102 includes a peak hold 131 to which a pulse wave signal is input, a window comparator 132 to which a signal processed by the peak hold 131 is input, and a bottom home signal to which a pulse wave signal is input. And a window comparator 135 to which signals processed by the bottom hold 134 and the bottom hold 134 are input. Further, an LED 133 that is turned on by a signal from the window comparator 132 and an LED 136 that is turned on by a signal from the window comparator 135 may be provided.

  The pulse wave signal is input to the peak hold 131 and bottom hold 134 circuits. Before these pulse wave signals enter the peak hold 131 and bottom hold 134 circuits, the detected pulse wave signals are transmitted to a certain degree by the amplifiers 111 and 112, respectively, in order for these circuits to operate properly. It is preferably amplified to the signal level. These hold circuits preferably have characteristics about the period of the pulse wave even when droop drops to 80%, for example.

  An example of output waveforms of the peak hold 131 and bottom hold 134 circuits is shown in FIG. FIG. 9 shows the relationship between the measurement time (horizontal axis) and the magnitude of the waveform (vertical axis). FIG. 9 (a) shows the waveform of the input pulse wave signal. FIG. 9B shows a waveform of a signal obtained by processing the input pulse wave signal by the bottom hold 134, and FIG. 9C shows a signal waveform obtained by processing the input pulse wave signal by the peak hold 131. Represents a waveform.

  In the present embodiment, as shown in FIG. 9B, the bottom hold 134 holds the bottom value of the waveform of the pulse wave in FIG. 9A, and the bottom value gradually increases with time. It is configured. Further, as shown in FIG. 9C, the peak hold 131 is configured to hold the peak value of the pulse wave waveform of FIG. 9A and gradually decrease with the passage of time. .

  By inputting the outputs from the peak hold 131 and the bottom hold 134 to the window comparators 132 and 135, respectively, it is determined whether or not there is a signal within a range between a predetermined upper limit reference voltage and a lower limit reference voltage. The polarity of the pulse wave signal can be determined. For example, by providing the reference voltage range of the window comparator 132 within a predetermined range of the positive region, a signal having a waveform having a positive peak value as shown in FIG. 9C obtained by the peak hold circuit. Is detected within the predetermined range of the reference voltage in the positive region, and the pulse wave in the case where the pulse wave appears on the right side of FIG. be able to. On the other hand, by providing the reference voltage range of the window comparator 135 within a predetermined range in the negative region, a waveform having a negative bottom value as shown in FIG. 9B obtained by the bottom hold circuit is obtained. By detecting that the signal is within the predetermined range of the reference voltage in the negative region, the pulse wave is detected when the pulse wave shows the polarity when the pressure is weak, as shown on the left side of FIG. can do.

  When the window comparator 132 determines that there is a signal within the range of the reference voltage, the LED 133 is turned on to display a determination result that the polarity of the pulse wave is the polarity when the pressure is strong. it can. When the window comparator 135 determines that there is a signal within the range of the reference voltage, the LED 136 is turned on to display a determination result that the pulse wave has the polarity when the pressure is weak. be able to. At this time, for example, the LED 133 may be configured as a red LED and the LED 136 may be configured as a green LED, and the polarity determination result may be notified by emitting red or green light.

In this way, due to the waveform of the pulsation signal detected by the first sensor 14, the change in polarity is shown to the user of the sample information detection unit 1, 3 according to the lighting state of the LEDs 133, 136. With this, it is possible to indicate the state of grip strength and instruct to adjust the applied force.
At this time, the first sensor 14 functions as a polarity detection unit that detects the polarity of the pulse wave of the pulsation signal, and the LEDs 133 and 136 function as the polarity notification unit 25 that changes the polarity.

(Pressing information detector)
The pressing information detection unit 103 detects the value of the pressing force detected by the grip strength sensor when the pulse wave polarity changes. In this embodiment, the press information detection unit 103 receives the output of the band pass filter 121 to which a pulse wave signal is input, the low pass filter 122 to which the signal from the band pass filter 121 is input, and the output of the low pass filter 122. The AD converter 123 to which the above signal is input is configured.

  As shown in FIG. 7, the change in the polarity of the pulse wave is considered to mean that the pulse wave is stopped and the blood flow sent from the heart is stopped at a certain pressure. That is, the maximum blood pressure value is detected by the fingertip. Of course, it is natural that this value becomes smaller with the heart, upper arm, wrist, and fingertip, and a commercially available sphygmomanometer is converted to the delivery pressure at the heart based on a large amount of medical measurement data. However, this value at the fingertip is in accordance with the systolic blood pressure, and for an individual, this value is sufficiently meaningful in terms of the deviation from the normal value to the normal value.

  In order to detect this pressure value, it can be seen that a slightly high specific frequency component is generated at a pressure at which the polarity near 4 [s] is switched as shown in FIG. A specific high frequency component of the part where the polarity is switched is detected by the band-bap filter 121. An example of waveform processing by the bandpass filter 121 is shown in FIG. FIG. 9 shows the relationship between the measurement time (horizontal axis) and the magnitude of the waveform (vertical axis), where (a) shows the waveform of the input pulse wave signal, and FIG. Represents a waveform in which a high-frequency portion is detected from the waveform of FIG.

  Further, the high-frequency component detected by the bandpass filter can sample the voltage value of the signal from the grip strength sensor 16 by using the output of the high-frequency component detected by the low-pass filter 122, and further, the AD conversion unit 123 can grip the grip strength sensor. By converting the signal from 16 into a digital signal from an analog signal, it is possible to provide a mechanism for detecting pressure information when the polarity is switched and holding the value as pressure information in a state showing the maximum blood pressure. .

  The value of the press information in the state indicating the maximum blood pressure is called after the next measurement, averaged, and updated as a reference value. This is also because the sampling pulse of the signal from the grip strength sensor 16 is obtained from the output of the peak hold 131 and the bottom hold 134 by catching the time point when both hold circuits output simultaneously or not simultaneously. Good.

  These values of the press information may be used as reference values for putting power on the next and subsequent hands, in addition to being used as reference values when the polarity is switched from the next time onward. For example, the values of the pressing information are called and compared with the calibration value of the grip strength sensor 16, and if the value of the grip strength sensor 16 becomes larger than the value of the pressing information, the value is held and displayed by a warning means. Or, by turning on the LED or outputting a sound, a warning that too much force can be applied can be issued. The warning means at this time functions as the grip strength notification unit 26.

(Pressing optimization part)
The press optimizing unit 104 optimizes the press that is the grip strength of the hand. In this embodiment, the pressure optimizing unit 104 includes a PLL that includes a phase comparator 143, a low-pass filter 144, a VCO 145, and a frequency divider 146 to which a pulse wave signal amplified by AGC is input. The sample hold 148 to which the signal from the timing generator 147 and the signal from the timing generator 147 are input and the pulse wave signal amplified by the AGC is input and the signal from the sample hold 148 Is input to the logic circuit 149. Further, LEDs 150 and 151 which are turned on by a signal from the logic circuit 149 may be provided.

  After the polarity is determined by the polarity determination unit 102, the pulse wave signal is subjected to AGC (Automatic Gain Control) by the AGC 141 until the dynamic range of the AD converter is full, and the pulse wave signal is amplified. By converting the amplified pulse wave signal from an analog signal to a digital signal by the AD converter 142, a pulse wave output can be obtained.

  Here, the grip strength of the hand gripping the specimen information detection unit, that is, the pressing force applied by the finger of the hand to the grip strength sensor of the first opening is finely controlled, thereby further optimizing the pressure. FIGS. 10A and 10B are diagrams showing an example of a change in the waveform of the pulse wave (volume pulse wave) when the pressing force is further changed with the selected polarity. 10 (a) and 10 (b) both show the waveform of a pulse wave signal having the same polarity. FIG. 10 (a) shows the pulse wave signal when a weak force is applied using a slightly weak finger sack. FIG. 10B shows the waveform of a pulse wave signal when a stronger force is applied using a slightly stronger finger sack.

  Here, L size (inner diameter 15 mm, length 12.5 mm) of Meklin (trade name, manufactured by KOKUYO S & T Co., Ltd.) is used as a slightly weak finger sack, and Meklin (product name, M size (inner diameter 13 mm, length 11 mm) of KOKUYO S & T Co., Ltd. is used. The relationship between the pressing force and the change in the waveform of the pulse wave is not always clear, but to change the pressing force, a slightly weaker finger sack with a relatively large inner diameter and a weaker tightening is used as a slightly weaker finger sack. A finger sack having a relatively small inner diameter and strong tightening is used. Of course, the change in the waveform of the pulse wave seen in FIGS. 10 (a) and 10 (b) is not limited to the case where the above finger sack is used.

  Even when the force is the same, if the force is applied, the peak value of the pulse wave increases, and at the same time, a change may be seen in the waveform of the pulse waveform called TW (tidal wave), and the main peak and TW The peak ratio relationship may change. For example, in FIG. 10B, the ratio of the main peak of TW is higher than the waveform of FIG. 10A, and the peak of the TW waveform is clear. By making this TW always have the same waveform, it is possible to adjust and optimize the applied pressure.

  For this purpose, first, a phase-locked loop (PLL) is applied by the phase comparator 143, the low-pass filter 144, the VCO 145, and the frequency divider 146 using the velocity pulse wave after AGC. Here, a 10-bit counter has a division ratio of 1024. Appropriate pressure can be obtained by comparing the phase of the second zero cross of the acceleration pulse wave after AGC, which seems to be almost close to the timing of the TW created by this PLL.

  This pressing adjustment will be described with reference to FIG. In FIG. 11, (a) represents the volume pulse wave detected by the first sensor, and (b) represents the velocity pulse wave detected by the first sensor. The velocity pulse wave has a characteristic pulse peak more clearly than the volume pulse wave, and the phase of the PLL is easily determined. For this reason, when the pulse wave detected by the first sensor is a volume pulse wave, the volume pulse wave of (a) is processed by the differentiating circuit to obtain the velocity pulse wave of (b) and then continues. It is preferable to use the processing in the PLL including the phase comparator 143 and the like. In the velocity pulse wave, as shown in FIG. 11B, a second peak appears due to the TW of the volume pulse wave, and the second peak of the velocity pulse wave can be used for adjusting the pressure. When MEMS-ECM is used as the first sensor, a velocity pulse wave as shown in (b) is obtained. In this case, the processing by the PLL is performed without performing the processing by the differentiating circuit 141. It can be carried out.

  In the PLL, first, the rising edge of the pulse wave signal input by the phase comparator 143 is detected, and the period from the rising edge of the pulse wave signal to the rising edge of the next pulse wave signal is detected as one cycle. The output from the phase comparator 143 is input to the low-pass filter 144, and the output frequency of the VCO 145 is adjusted by the output. The 1/1024 frequency divider 146 divides one cycle detected in the pulse wave signal by 1024. A total of 1024 counts of 0 to 1023 in one cycle is output to the timing generator 147, and the signal is returned to the phase comparator 143 to synchronize with the input pulse wave signal. That is, a phase lock of 1024 times is applied at the peak position of the velocity pulse wave shown in FIG. 11 (d), and as shown in FIG. 11 (c), the pulse wave signal is input from the input pulse wave signal by the PLL. A 1024 count obtained by dividing one cycle by 1024 can be output to the timing generator 147. Here, the position of the timing of the second peak of the velocity pulse wave is shown in FIG.

  The timing generator 147 outputs a signal to the sample hold 148 in accordance with the counter output from the PLL frequency divider 146. The timing generation unit 147 counts when the output of the counter input from the PLL counts from 0 to become a specific number, for example, when the output of the 10-bit counter reaches 300 (in such a case, “timing The signal of the amplified pulse wave from the AGC 141 is sampled and held by the sample hold 148 and further input to the logic circuit 149.

  The logic circuit 149 determines whether or not the pressing is appropriate based on the input sampled and held signal, and lights the LEDs 150 and 151 according to the determination result. As shown as an example in FIGS. 11 (f) to 11 (h), when the waveform of the pulse wave signal is represented by an acceleration pulse wave, the acceleration due to the change in the pressure is caused by the TW waveform of the pulse wave waveform. The position of the second peak of the pulse wave changes. For example, when the acceleration pulse wave in the case of the appropriate pressure is expressed as FIG. 11 (f), when the pressure is high, as shown in FIG. 11 (g), the second peak position of the acceleration pulse wave is more than in the case of the appropriate pressure. Appears at the previous timing. On the other hand, when the pressure is low, as shown in FIG. 11 (h), the second peak position of the acceleration pulse wave appears at a later timing than the case of the appropriate pressure. As described above, the timing of the second peak from the rising of the pulse wave signal of the acceleration pulse wave in the case of the appropriate pressure is determined in advance, and from the rising of the pulse wave signal of the acceleration pulse wave in the pulse wave for which the pressure is to be optimized. By comparing with the timing of the second peak, it can be determined whether the pressure is high, low, or appropriate, and can be optimized by adjusting the pressure according to the determination result. .

  In the above description, an example in which the amplified pulse wave signal from the AGC 141 is sampled and held by the sample hold 148 and processed by the logic circuit 149 at the timing of 300 has been described. Can be performed at an arbitrary timing.

Further, in the above description, an example in which one period is divided into 1024 with one period from the rise of the peak to the rise of the next peak is not limited thereto. However, the present invention is not limited thereto, and can be arbitrarily adjusted by adjusting the frequency divider 146. The signal processing may be performed by dividing the number into a number.
Alternatively, the pressure may be optimized so that the ratio between the first and second peaks of the acceleration pulse wave is obtained and combined.

  In consideration of such fine adjustment, it may be difficult to optimize the pressing with only one hand unless used. For this reason, it is desirable to adjust the slight press by attaching the finger on the opposite side touching the first opening and the sensor to the finger touching the first opening and the sensor.

[1-4. Application example of specimen information detection unit according to first embodiment]
An electric shaver device, which is an appliance that is provided with a storage battery 47 in the casing parts 11 and 21 and is driven by electric power supplied from the storage battery 47 and is used with the cradle 2 that can hold the casing parts 11 and 21 In addition, an electric toothbrush device is known. The sample information detection units 1, 3, 8, and 9 according to the first embodiment of the present invention can be applied to an electric appliance having such a grip portion.
Therefore, an example in which the sample information detection units 1 and 3 according to the first embodiment of the present invention are applied to an electric shaver device and an electric toothbrush device will be described below. In the following, the electric shaver device is also simply referred to as an electric shaver, and the electric toothbrush device is also simply referred to as an electric toothbrush.

<Application example of electric shaver>
An electric shaver (manufactured by Philips) having a main body (body, grip portion) was used as an application example of the specimen information detection unit according to the first embodiment of the present invention.
Vibration is applied to the main body of the electric shaver, and a cylinder for forming a cavity in the main body 3 is brought into contact with the main body and attached with tape, and the front end of the cylinder not contacting the main body is made of butyl rubber. The O-ring was attached, and ECM (SPM0408, trade name, manufactured by KNOWLES) was attached to the surface of the main body in the cylinder.
Thus, the first opening 12 is formed by the cylinder and the O-ring with the main body portion of the electric shaver as the housing portion, and the first cavity 13 communicated with the first opening 12 by the surface of the main body portion and the cylinder. An ECM is formed in the first cavity 13 as the first sensor 14.
Hold the body of the electric shaver so that your fingers are in close contact with the O-ring of the electric shaver to which this ECM is attached. Was detected.

  FIG. 17A is a diagram showing the relationship between the frequency and the strength of the noise for the noise of the electric shaver. FIG. 17B is a diagram showing the waveform of the volume pulse wave of the pulsation signal detected from the fingertip by ECM. In the left area of the figure, when the electric shaver is turned on, the right area of the figure is electrically driven. The waveform of the pulse wave when the power source of the shaver is turned off is shown. FIG. 17C is a diagram showing the velocity pulse wave waveform of the pulsating signal detected from the fingertip by ECM. In the left region of the figure, when the electric shaver is turned on, the right region of the figure Fig. 4 shows the waveform of a pulse wave when the power source of the electric shaver is turned off.

  As shown in FIGS. 17B and 17C, when the power source of the electric shaver is turned on or off, the pulse wave waveform can be divided into bands from the noise component of the electric shaver.

The electric shaver to which the sample information detection unit according to the first embodiment of the present invention is applied is placed on the cradle 2 when not in use so that the storage battery 47 is charged in a non-contact state and the cradle 2 is Thus, the measurement signal stored in the storage means 29 can be read and transmitted from the sample information detection unit 1, 3, 8, 9 to an external computer.
At this time, the cradle 2 in the sample information detection unit 1, 3, 8, or 9 may also serve as the cradle for the electric shaver device.

<Application example of electric toothbrush>
As shown in FIG. 22, the main body part (body, grip part) 311 and a brush part 312 are provided, and an electric toothbrush (manufactured by Toray Industries, Inc.) 301 provided with operation buttons 313, 314 and 315 on the main body part 311 is used. An application example of the specimen information detection unit according to the first embodiment of the invention is used.

  Vibration is applied to the body portion 311 of the electric toothbrush, and a cylinder 321 for forming a cavity in the lower center of the body portion 311 is attached to the body portion 311 with a tape, and is not in contact with the body portion of the cylinder 321. An O-ring 322 made of butyl rubber was attached to the tip on the side, and an ECM (SPM0408, trade name, manufactured by KNOWLES) 323 was attached to the surface of the main body 311 in the cylinder 311.

  As a result, the first opening 12 is formed by the cylinder 321 and the O-ring 322 with the main body 311 of the electric toothbrush as the casings 11 and 21, and the first opening 12 is formed by the surface of the main body 311 and the cylinder 321. A first cavity 13 communicating with the ECM 323 is formed, and an ECM 323 is mounted as the first sensor 14 in the first cavity 13.

  The electric toothbrush body was gripped so that the finger was opposed to and closely attached to the O-ring 322 of the electric toothbrush with the ECM attached, the electric toothbrush was turned on, and the pulsation signal from the fingertip was detected. .

  FIG. 18A is a diagram showing the relationship between the frequency and the strength of noise for the vibration component of the electric toothbrush. FIG. 18B is a diagram showing the waveform of the volume pulsation wave of the pulsation signal detected from the fingertip by the ECM when the electric toothbrush is powered on. FIG. 18C is a diagram showing the velocity pulse wave waveform of the pulsation signal detected from the fingertip by ECM when the electric toothbrush is powered on.

  As shown in FIG. 18C, it is difficult to obtain the waveform of the pulse wave due to the influence derived from the vibration component of the electric toothbrush. On the other hand, as shown in FIG. 18B, the volume pulse wave was not affected by the vibration component of the electric toothbrush, and a pulse wave waveform could be obtained.

The electric toothbrush to which the specimen information detection unit according to the first embodiment of the present invention is applied is placed on the cradle 2 when not in use, so that the storage battery 47 is charged in a non-contact state and the cradle 2 is mounted. Thus, the measurement signal stored in the storage means 29 can be read and transmitted from the sample information detection unit 1, 3, 8, 9 to an external computer.
At this time, the cradle 2 in the specimen information detection units 1, 3, 8, and 9 may also serve as a cradle for the electric toothbrush device.

[1-5. Effect of specimen information detection unit according to first embodiment]
According to the specimen information detection units 1, 3, 8, and 9 according to the first embodiment of the present invention, the casing parts 11 and 21 are formed in a columnar shape or an egg shape, so that the casing parts 11 and 21 are formed. It will be gripped by hand along the outline of. As a result, for example, when an emergency is felt, immediately after a meal, or while sleeping, when the user thinks about using the bag, the sample information detection unit 1, 3, 8, or 9 may be held without excessive force. It becomes possible to hold it in the same stable and natural shape every time. In addition, even when the sample information detection unit is gripped in the dark or when getting up, it can be stably and naturally gripped. Moreover, it is only necessary to hold the housing parts 11 and 21, and no complicated fixing is required. Thereby, the specimen information detection unit 1 can quickly grasp the specimen information detection unit 1, 3, 8, 9 and stabilize the force of gripping with the hand, thereby providing a quick and stable detection result of the pulsation signal. 3, 8, 9 can be provided.

  Further, in the case where the finger guide groove 15 is formed in the sample information detection unit 1, 3, 8, 9, the casings 11, 21 can be grasped by hand so that the finger 91 is along the guide groove 15. As a result, the position of the finger is stabilized when the casings 11 and 21 are gripped by hand, and the position of the finger can be prevented from being shifted when the pulsation signal is detected. Thereby, in addition to grasping the specimen information detection units 1, 3, 8 and 9 more quickly, the first opening 12 provided in the guide groove 15 or the light transmission part 23 and the finger 91 can be easily aligned. Thus, it is possible to provide the specimen information detection units 1, 3, 8, and 9 that provide a detection result of a more rapid and stable pulsating signal.

  In addition, the first opening 12 is formed in a portion of the casing 11, 21 that should be opposed to the finger 91 of the hand holding the casing 11, 21, and the first opening 12 is opposed to the finger 91. A blood vessel in a finger 91 having a spatial structure (closed cavity) in which the first cavity 13 is closed in a state where the housing parts 11 and 21 are gripped by the hand, and the first sensor 14 is input through the first opening 12. In the case where the pulsating signal is detected as the pressure information propagating in the first cavity 13, the pulsating signal of the blood vessel is obtained even if the first sensor 14 is not directly above the capillary or the blood vessel, as in the first embodiment. Can be detected. That is, it is possible to provide the sample information detection units 1 and 3 having a mechanism that does not require the accuracy of the positional relationship between the first sensor 14 and the blood vessel.

  Further, when the diameter of the first opening 12 is limited to a predetermined size, the sample information detection units 1 and 3 have a range of pressure information received by the first opening 12 as in the first embodiment. The sensing range as a pressure sensor of the present sample information detection units 1 and 3 is limited to be narrow. Thereby, it is possible to provide the specimen information detection units 1 and 3 having high directivity (or spatial resolution) compared to the case where sensing is simply performed using an open system using a sensor such as a piezoelectric element or a microphone. Further, the S / N ratio and sensitivity of the pulsation signal can be improved by detecting the pulsation signal at a position close to the blood vessel using the directivity of the present specimen information detection units 1 and 3.

  Further, when the first opening 12 or the light transmission part 23 of the specimen information detection unit 1, 3, 8, 9 is a part in contact with the skin part corresponding to the joint part of the finger 91, the artery is confirmed. It is possible to detect pulsation from the blood vessels existing in the finger joint, and the pulsation of the blood vessel itself is relatively larger than detecting the pulsation signal from the capillaries by bringing the sensor into contact with the abdomen of the fingertip. A stable pulse wave can be obtained.

In addition, according to an electric appliance such as an electric shaver device or an electric toothbrush device to which the sample information detection units 1 and 3 of the present invention are applied, the casing portion of the sample information detection unit 1 or 3 is used as a grip portion of the electric appliance. Thus, it is possible to detect a pulsating signal while using the electric appliance, and it is possible to easily measure the pulsating signal on a daily basis and regularly.
Further, the cradle of the specimen information detection unit 1 or 3 is also used as a cradle of the electric appliance, so that it is convenient for charging and transferring measurement results.

[A2. Description of First Modification of First Embodiment]
[2-1. Sample Information Detection Unit According to First Modified Example of First Embodiment]
The sample information detection unit according to the first modification of the first embodiment of the present invention is configured as shown in FIG. 12 as an example. Here, an example in which the first modification is applied to the first embodiment described above will be described.

  The sample information detection unit according to the first modification of the first embodiment is configured in the same manner as the above-described first embodiment except for a part of the configuration, and the same as the above-described sample information detection unit. The description will be omitted, and description will be made using the same reference numerals.

<Configuration of specimen information detection unit>
The sample information detection units 5 and 81 according to the first modification of the first embodiment of the present invention include, as an example, a housing 31 as shown in FIGS. 12 (a) and 21 (a). The body part 11 is configured as a cylindrical member, and a plurality of pressure-sensitive elements 38a to 38c functioning as the first sensors 34a to 34c or a plurality of light receiving elements 78a to 78c functioning as the first sensors 34a to 34c are provided. Yes. Alternatively, the sample information detection units 6 and 82 according to the first modification of the first embodiment of the present invention include, as an example, a housing 41 as shown in FIGS. 12 (b) and 21 (b). The housing portion 41 is configured as an egg-shaped member, and a plurality of pressure sensitive elements 38a to 38c functioning as the first sensors 34a to 34c, or a plurality of light receiving elements 78a to 78c functioning as the first sensors 34a to 34c are provided. It has been.

  As shown in FIGS. 12A and 12B, the specimen information detection units 5 and 6 according to the first modification of the first embodiment of the present invention include a plurality of second housings in the housing portions 31 and 41, respectively. The first openings 32a to 32c are formed, the plurality of first cavities 33a to 33c are formed, and the plurality of pressure sensitive elements 38a to 38c functioning as the first sensors 34a to 34c are provided. Alternatively, a plurality of sample information detection units 81 and 82 according to the first modification of the first embodiment of the present invention are provided in the casing portions 31 and 41 as shown in FIGS. The first light sources 77a to 77c, the light transmitting portions 73a to 73c, and a plurality of light receiving elements 78a to 78c functioning as the first sensors 34a to 34c are provided.

  Furthermore, the sample information detection units 5, 6, 81, 82 according to the first modification of the first embodiment of the present invention are shown in FIG. 12 (a), FIG. 12 (b), FIG. 21 (a), FIG. As shown in b), it is preferable that guide grooves 35 a to 35 c for a plurality of fingers are formed on the front wall portions of the housing portions 31 and 41. The casing units 31 and 41 are preferably provided with grip strength sensors 36a to 36c.

  In addition, the housing portions 31 and 41 include pressure-sensitive elements 38a to 38c that function as the first sensors 34a to 34c or light receiving elements 78a to 78c that function as the first sensors 34a to 34c, and grip strength sensors 36a to 36c. It is preferable to include a signal processing unit 23 for processing the signal detected in step (b).

  In the present embodiment, the configuration of the sample information detection unit in the case where the housing part is gripped with the left hand will be described, but FIGS. 12A, 12B, and 21A are used so that the housing part is gripped with the right hand. ), And the shape of the guide grooves 35a to 35c shown in FIG. Further, in the present embodiment, when there are three sets each of the first opening or light transmitting portion, the first cavity, the pressure sensitive element functioning as the first sensor or the light receiving element functioning as the first sensor, and the guide groove The configuration of the sample information detection unit will be described. However, the first opening or the light transmitting portion is formed so that the first opening or the light transmission portion is formed at a portion of the casing that should face each of the fingers of the hand that holds the casing 31. One opening or light transmitting portion, a cavity, a pressure-sensitive element that functions as a first sensor or a light-receiving element that functions as a first sensor, and a guide groove need only be formed, and 2 corresponding to two fingers. There may be a set, four sets may exist corresponding to four fingers, or five sets may exist corresponding to five fingers.

(Case)
The casing portions 31 and 41 have an outer shape that can be grasped by a hand, and are portions that function as the casings of the sample information detection units 5, 6, 81, and 82. As shown in FIGS. 12A and 12B, the housing portions 31 and 41 are formed with first openings 32a to 32c and first cavities 33a to 33c, and the first sensors 34a to 34c. Pressure-sensitive elements 38a to 38c are provided. Alternatively, as shown in FIGS. 21A and 21B, the housing portions 31 and 41 function as first light sources 77a to 77c, light transmitting portions 73a to 73c, and first sensors 34a to 34c. Light receiving elements 78a to 78c are provided.

  The casings 31 and 41 are not limited in shape and size as long as they can be gripped by hand. From the viewpoint of ease of gripping and ease of holding, the housings 31 and 41 are not limited to FIGS. ), The casing 31 of the sample information detection units 5 and 81 is configured as a cylindrical member or a columnar member, and the first openings 32a to 32c and the first cavities 33a to 33c are formed on the side surfaces. The first sensors 34a to 34c 34a to 34c are formed, or the first light sources 77a to 77c, the light transmitting portions 73a to 73c, and the light receiving elements 78a to 78c that function as the first sensors 34a to 34c are provided. Preferably it is. Or as shown in FIG.12 (b), FIG.21 (b), the housing | casing part 41 of the sample information detection units 6 and 82 is comprised as an egg-shaped member, Of the egg shape, near the center of a long side direction. First openings 32a to 32c and first cavities 33a to 33c are formed at portions where the radius of curvature is large and the curve drawn by the shape of the end portion is gentle (hereinafter also simply referred to as the vicinity of the center), and the first sensors 34a to 34c are formed. 34c34a to 34c are preferably provided, or first light sources 77a to 77c, light transmitting portions 73a to 73c, and light receiving elements 78a to 78c that function as the first sensors 34a to 34c are preferably provided. Or the housing | casing part of the sample information detection unit may be comprised as a prismatic member.

(First opening)
As shown in FIG. 12A and FIG. 12B, the first openings 32 a to 32 c are housing parts 31, 41 that should face a plurality of fingers of the hand holding the housing parts 31, 41. A plurality of openings are provided at the part of the sample information detection unit 5, and when the casing parts 31 and 41 of the sample information detection units 5 and 6 are gripped by a hand, the parts contact with the abdominal parts of a plurality of fingers of the hand. is there. The first openings 32a to 32c are preferably formed in finger guide grooves 35a to 35c. The first openings 32a to 32c communicate with the first cavities 33a to 33c, respectively.

(First cavity)
As shown in FIGS. 12 (a) and 12 (b), the first cavities 33a to 33c communicate with the first openings 32a to 32c, and the first openings 32a to 32c are connected to the respective fingers. Each of the housing portions 31 and 41 is formed in a space structure in which the housing portions 31 and 41 are closed in a state of being opposed to each other and are closed. The closed space structure formed by the first cavities 33a to 33c in this manner is also referred to as “Closed Cavity”. Pressure sensitive elements 38a to 38c functioning as first sensors 34a to 34c are provided in the first cavities 33a to 33c, respectively.

(First light source)
As shown in FIG. 21A and FIG. 21B, a plurality of first light sources 77a to 77c are provided in the casing portions 31 and 41, and a plurality of fingers of the hand holding the casing portions 31 and 41 are provided. An optical signal is generated toward

A plurality of light transmitting portions 73a to 73c are provided on the front wall portions of the casing portions 81 and 82, and optical signals emitted from the first light sources 77a to 77c are transmitted through the light transmitting portions 73a to 73c described later, Each of the light receiving elements 78a to 78c functions as first sensors 34a to 34c, which will be described later, by passing through the respective light transmitting portions when the light signals that hit the plurality of fingers of the hand holding the housing portions 81 and 82 and reflected by the fingers pass through the respective light transmitting portions. The direction in which each optical signal emitted from the first light sources 77a to 77c is not perpendicular to the end surfaces of the casing portions 31 and 41 so that the optical signal is emitted at a predetermined angle as detected by 78c. Is preferably provided.
The first light sources 77a to 77c function as photo interrupters (also referred to as photo reflectors) together with the light transmitting parts 73a to 73c and the light receiving elements 78a to 78c functioning as the first sensors 34a to 34c.

(Light transmission part)
As shown in FIGS. 21A and 21B, the light transmitting portions 73a to 73c are provided on the housing portions 81 and 82 that should face the fingers of the hand holding the housing portions 81 and 82, respectively. A plurality of materials are provided in the region, and are made of a transmissive material that can transmit optical signals from the first light sources 77a to 77c.

  The light transmitting portions 73a to 73c are provided on the front wall portions of the housing portions 81 and 82, and the light transmitting portions in which a plurality of fingers of the hand holding the housing portions 81 and 82 are provided on the housing portions 81 and 82. When facing the respective light sources 73a to 73c, the light signals from the respective first light sources 77a to 77c pass through the respective light transmitting portions 73a to 73c and hit the respective fingers, and the light signals reflected by the respective fingers 91 and reflected by the respective light beams It is preferable that the light receiving elements 78a to 78c that pass through the transmitting portions 73a to 73c and function as the first sensors 34a to 34c are detected.

(First sensor)
As shown in FIGS. 12 (a), 12 (b), 21 (a), and 21 (b), the pressure sensitive elements 38a to 38c or the light receiving elements 78a to 78c functioning as the first sensors 34a to 34c are , Which are provided in a plurality of casing parts 31 and 41, detect pulsation signals of blood vessels in a plurality of fingers of the hand holding the casing parts 31 and 41, and output them as pulsation signals (pulse wave signals) It is.

  As shown in FIGS. 12A and 12B, a plurality of first openings 32a to 32c are formed in the casing portions 31 and 41 of the sample information detection units 5 and 6, and a plurality of first openings 32a to 32c are formed. When the one cavities 33a to 33c are formed in the casing portions 31 and 41, it is preferable that a plurality of pressure sensitive elements 38a to 38c are provided as the first sensors 34a to 34c. At this time, the pressure-sensitive elements 38a to 38c functioning as the first sensors 34a to 34c convert the pulsation signals of the blood vessels in the respective fingers inputted through the first openings 32a to 32c to the respective pulsation signals. Detected as pressure information propagating in the first cavities 33a to 33c.

  As shown in FIG. 21A and FIG. 21B, a plurality of first light sources 77a to 77c and a plurality of light transmission portions 73a to 73c are provided in the casing portions 31 and 41 of the specimen information detection units 81 and 82, respectively. Are preferably provided with a plurality of light receiving elements 78a to 78c as the first sensors 34a to 34c. At this time, the light receiving elements 78a to 78c functioning as the first sensors 34a to 34c convert the pulsation signals of the blood vessels in the respective fingers into optical signals from the first light sources 77a to 77c due to the pulsation signals, respectively. Detection is performed by receiving an optical signal reflected by the finger and reflected.

  In addition, even if it is a case where a pulsation signal is detected using the pressure sensitive elements 38a-38c as a 1st sensor, or it is a case where a pulsation signal is detected using the light receiving elements 78a-78c, it mentions later. Signal processing for the pulsating signal can be performed in the same manner.

(Guide groove)
As shown in FIGS. 12 (a), 12 (b), 21 (a), and 21 (b), the guide grooves 35a to 35c are formed on each finger when the housing portions 31 and 41 are grasped by hand. This is a part that serves as a guide. In the guide grooves 35a to 35c, first openings 32a to 32c or light transmitting portions 73a to 73c are formed, respectively, and the housing portion 31 is formed such that a plurality of fingers of the hand are along the guide grooves 35a to 35c. , 41 so that the first opening or the light transmitting portion is formed in a portion to be opposed to the finger of each hand when the first opening is formed in the vicinity of the ends 37a to 37c of the guide grooves 35a to 35c. 32a to 32c or light transmitting portions 73a to 73c are preferably formed.

(Grip strength sensor)
As shown in FIG. 12A, FIG. 12B, FIG. 21A, and FIG. 21B, the grip strength sensors 36a to 36c are provided in the first openings 32a to 32a of the housing portions 31 and 41, respectively. 32c or around the light transmission parts 73a to 73c, respectively, detects the strength of the hand grip as a pressing force (pressing signal) and outputs it as a pressing signal. Moreover, it is preferable that the casing units 31 and 41 are provided with a grip strength notification unit 26 that notifies the grip strength of the hand due to outputs from the grip strength sensors 36a to 36c (FIG. 25). , 26).

(Signal processing part)
The signal processing unit 101 processes a pulsation signal (pulse wave signal) detected by the first sensors 34 a to 34 c and a pressing signal regarding the grip strength of the hand detected by the grip strength sensor 16. It is an electric circuit. The signal processing unit 101 includes a polarity determination unit 102, a pressing information detection unit 103, a pressing optimization unit 104, and an averaging processing unit 105 as electric circuits (FIGS. 25 and 26).

[2-2. Functional Configuration of Specimen Information Detection Unit According to First Modification of First Embodiment]
Hereinafter, an example of a functional configuration of the sample information detection unit 5, 6, 81, 82 according to the first modification of the first embodiment of the present invention will be described.

(In the case of a specimen information detection unit provided with a pressure sensitive element)
When functionally representing the sample information detection units 5 and 6 according to the first modification of the first embodiment of the present invention, as shown in FIG. 25, the sample information detection units 5 and 6 include the first sensors 34a to 34c. Pressure-sensitive elements 38a to 38c, grip strength sensors 36a to 36c, polarity notification unit 25, grip strength notification unit 26, sample detection sensor 27, sample notification unit 28, storage means 29, clock 42, GPS antenna 43, a GPS processing circuit 44, a body temperature detection means 45, an outside air temperature detection means 46, a storage battery 47, and a signal processing unit 101. The signal processing unit 101 includes a polarity determination unit 102, a pressure information detection unit 103, and a pressure optimization unit. 104 and an averaging processing unit 105.

  Blood pressure pulsation waves (pulsation signals) are detected as pressure information resulting from the pulsation signals by the pressure-sensitive elements 38a to 38c functioning as the first sensors 34a to 34c, and are gripped by the grip strength sensors 36a to 36c. Signals detected by the pressure-sensitive elements 38a to 38c and the grip strength sensors 36a to 36c functioning as the first sensors 34a to 34c are sent to the signal processing unit 101, and the pressure information resulting from the strength of the pressure is detected. The determination unit 102, the press information detection unit 103, the press optimization unit 104, and the averaging processing unit 105 are configured to process the signal.

(In the case of a specimen information detection unit provided with a light receiving element)
When the sample information detection units 81 and 82 according to the first modification of the first embodiment of the present invention are functionally represented, as shown in FIG. 26, the sample information detection units 81 and 82 are first sensors 34a to 34c. Light receiving elements 78a to 78c, grip strength sensors 36a to 36c, first light sources 77a to 77c, polarity notification unit 25, grip strength notification unit 26, sample detection sensor 27, sample notification unit 28, storage unit 29, A clock 42, a GPS antenna 43, a GPS processing circuit 44, a body temperature detection means 45, an outside air temperature detection means 46, a storage battery 47, and a signal processing unit 101 are provided. The signal processing unit 101 includes a polarity determination unit 102, a pressing information detection unit. 103, a pressing optimization unit 104, and an averaging processing unit 105.

  The light-receiving elements 78a to 78c functioning as the first sensors 34a to 34c detect blood vessel pulsation waves (pulsation signals) as optical signals resulting from the pulsation signals, and the grip strength sensors 36a to 36c Signals detected by the light receiving elements 78a to 78c functioning as the first sensors 34a to 34c and the grip strength sensors 36a to 36c are detected by the pressure information due to the strength, and are sent to the signal processing unit 101, and the polarity The determination unit 102, the press information detection unit 103, the press optimization unit 104, and the averaging processing unit 105 are configured to process the signal.

[2-3. Operation of Specimen Information Detection Unit According to First Modification of First Embodiment]
Below, an example of operation | movement of the sample information detection unit 5, 6, 81, 82 concerning the 1st modification of 1st embodiment of this invention is demonstrated.

<Detection of pulsation signal and pressing force>
(In the case of a specimen information detection unit provided with a pressure sensitive element)
A plurality of first openings 32 a to 32 c are formed in the casing portions 31 and 41 of the sample information detection units 5 and 6, and a plurality of first cavities 33 a to 33 c are formed in the casing portions 31 and 41. The operation when a plurality of pressure sensitive elements 38a to 38c are provided as the first sensors 34a to 34c will be described.

  Grip the casings 31 and 41 with the hand so that the fingertips are pressed so that the first joints and the first openings 32a to 32c are in contact with the first joints from the tips of the plurality of fingertips of the sample hand. The first cavities 33a to 33c are each formed as a closed space structure (closed cavity). In this state, micro blood vessels, capillaries, or joint portions at the fingertips of a plurality of fingers are obtained by the pressure sensitive elements 38a to 38c functioning as the first sensors 34a to 34c provided in the first openings 32a to 32c, respectively. The pulse wave (pulsation signal) in the arterial blood vessels existing in the blood is detected as pressure information. Further, the grip strength sensors 36a to 36c provided in the peripheral portions of the first openings 32a to 32c are used to determine the grip strength of the hand with each finger, and to press the grip strength sensors 36a to 36c. Signal).

(In the case of a specimen information detection unit provided with a light receiving element)
A plurality of first light sources 77a to 77c and a plurality of light transmitting portions 73a to 73c are provided in the casing portions 31 and 41 of the specimen information detection units 81 and 82, and a plurality of light receiving elements are used as the first sensors 34a to 34c. The operation when 78a to 78c are provided will be described.

  A plurality of fingers of the hand grasping the casing portions 31 and 41 so that an optical signal emitted from each of the first light sources 77a to 77c is applied between the tips of the fingertips of the sample hand and the first joint. The housing parts 31 and 41 are held by the hand so as to face the light transmitting parts 73a to 73c and press the fingertips against the light transmitting parts 73a to 73c, respectively. In this state, the optical signals from the first light sources 77a to 77c are transmitted through the light transmitting portions 73a to 73c and hit the fingers, respectively, and the light signals reflected by the fingers 91 are transmitted through the light transmitting portions 73a to 73c, respectively. It is detected by each of the light receiving elements 78a to 78c as the first sensors 34a to 34c. Accordingly, the light receiving elements 78a to 78c functioning as the first sensors 34a to 34c generate pulse waves (pulsation signals) in the arterial blood vessels existing in the fine blood vessels, capillaries, or joint portions at the fingertips of the fingers. The optical signal from the first light sources 77a to 77c due to the pulsation signal is reflected by the respective fingers and is reflected to detect the intensity of the optical signal. In addition, the grip strength sensors 36a to 36c provided in the peripheral portions of the light transmitting portions 73a to 73c are used to determine the grip strength of the hand with the respective fingers, and to press the grip strength sensors 36a to 36c (press signals). ) To detect.

<Processing of multiple pulsatile signals>
Next, a plurality of pulse waves (pulsation signals) detected as pressure information by the pressure sensitive elements 38a to 38c functioning as the first sensors 34a to 34c, or light receiving elements 78a to 78a functioning as the first sensors 34a to 34c. Signal processing that averages a plurality of signals for a plurality of pulse waves (pulsation signals) detected as optical signals by 78c will be described.

  In the following description, a plurality of first openings 32a to 32c are formed in the casing portions 31 and 41 of the specimen information detection units 5 and 6, and the plurality of first cavities 33a to 33c are formed as the casing portions. Although the case where a plurality of pressure sensitive elements 38a to 38c are provided as the first sensors 34a to 34c will be described, a plurality of second sensors are provided in the casing portions 11 and 21 of the specimen information detection units 8 and 9. Even when one light source 77a to 77c and a plurality of light transmission portions 73a to 73c are provided and a plurality of light receiving elements 78a to 78c are provided as the first sensor, signal processing can be performed in the same manner.

  A plurality of pulse waves (pulsation signals) detected as pressure information by the pressure sensitive elements 38a to 38c functioning as the first sensor may be subjected to signal processing for averaging the plurality of signals by the averaging processing unit 105. preferable. Similarly, a plurality of pressing forces (pressing signals) detected by the grip strength sensors 36a to 36c are preferably subjected to signal processing for averaging the plurality of signals. This signal processing will be described with reference to the block diagram shown in FIG.

  FIG. 13 is a block diagram illustrating a configuration of an averaging processing unit 105 for performing signal processing for averaging signals from the plurality of first sensors 34a to 34c and signals from the plurality of grip strength sensors 36a to 36c. It is. The averaging processing unit 105 receives outputs from the sampling pulse detection units 211, 213, and 215 and the sampling pulse detection units 211, 213, and 215 to which signals from the first sensors 34a to 34c are input, respectively, and receives a grip strength sensor. AD conversion units 212, 214, and 216 to which signals from 36a to 36c are input, pulse wave signal averaging unit 221 to which signals from sampling pulse detection units 211, 213, and 215 are input, and AD conversion units 212 and 214, respectively. 216 includes a pressing signal averaging unit 222 to which signals from 216 are input.

  Pulse wave signals from the first sensors 34 a to 34 c are input to the sampling pulse detection units 211, 213, and 215, and further output to the pulse wave signal averaging unit 221. The pulse wave signal averaging unit 221 averages the pulse wave signal, whereby an averaged pulse wave signal can be obtained.

  The pulse wave signals from the first sensors 34 a to 34 c are sampled by the sampling pulse detectors 211, 213, and 215, and the signals at the timing at which the pulse waves are detected are input to the AD converters 212, 214, and 216. . The AD converters 212, 214, and 216 convert the pressure signals input from the grip strength sensors 36a to 36c in accordance with the detected timing of the pulse wave from analog signals to digital signals, and further average the pressure signals. Output to the unit 222. The pressure signal is averaged by the pulse wave signal averaging unit 222, whereby an averaged pressure signal can be obtained.

  Note that such averaging signal processing may be performed by the averaging processing unit 105 being provided for signal processing of the specimen information detection unit, or each of the first sensors 34a to 34 or the grips. The signals obtained from the strength sensors 36a to 36c may be stored in the storage unit 29, transmitted from the storage unit 29 to an external computer, and signal processing may be performed by the external computer.

<Pressing state control>
By inputting the averaged pulse wave signal and the averaged pressure signal obtained by the averaging processing unit 105 to the polarity determination unit 102, the pressure information detection unit 103, and the pressure optimization unit 104. The pressed state can be controlled in the same manner as the sample information detection unit of the first embodiment described above.

[2-4. Application Example of Specimen Information Detection Unit According to First Modification of First Embodiment]
The sample information detection units 5, 6, 81, and 82 according to the first modification of the first embodiment of the present invention can be applied to an electric appliance having a grip portion such as an electric shaver device or an electric toothbrush device. is there.
At this time, the cradle 2 in the specimen information detection unit 5, 6, 81, 82 may also serve as an electric shaver device or an electric toothbrush device cradle.

[2-5. Effect of specimen information detection unit according to first modification of first embodiment]
According to the specimen information detection units 5, 6, 81, and 82 according to the first modification of the first embodiment of the present invention, in addition to the effects obtained in the first embodiment, a plurality of first sensors 34a to 34c. By obtaining an averaged pulse wave signal from the pulsation signal detected by the above, it is possible to measure the pulsation signal more accurately and more reliably than when detecting from only a single first sensor. A pulse wave can be obtained. Further, by obtaining an averaged pressing signal from the pressing signals detected by the plurality of grip strength sensors 36a to 36c, it is possible to obtain a more accurate grip than when detecting only from a single grip strength sensor. The strength can be measured, and a reliable grip strength can be obtained. Furthermore, since the grip strength is accurate, it becomes easy to stabilize the measurement conditions while keeping the grip strength of the hand constant, and the measurement accuracy of the pulsation signal can be further improved.

[B1. Description of Second Embodiment of the Present Invention]
[3. Sample Information Detection Unit]
[3-1. Sample configuration of specimen information detection unit]
The sample information detection unit according to the second embodiment is configured in the same manner as the sample information detection unit according to the first embodiment described above except for a part of the configuration, and is similar to the sample information detection unit described above. Will be described using the same reference numerals.
<Configuration of specimen information detection unit>

  The sample information detection unit 7 according to the second embodiment of the present invention includes housing portions 11 and 21 as shown in FIGS. 1 (a), 1 (b), 20 (a), and 20 (b). The housing portion 11 is configured as a columnar member or an egg-shaped member, and the first sensor 14 is provided.

  In the sample information detection unit 7 according to the second embodiment of the present invention, as shown in FIGS. 1 (a) and 1 (b), a first opening 12 is formed in the housing parts 11 and 21. The first cavity 13 is preferably formed, and a pressure-sensitive element 24 that functions as the first sensor 14 is preferably provided. Alternatively, in the specimen information detection unit 7 according to the second embodiment of the present invention, as shown in FIG. 20A and FIG. It is preferable that the light receiving element 18 which functions as the part 23 and the 1st sensor 14 is provided.

  In the specimen information detection unit 7 according to the second embodiment of the present invention, it is preferable that a finger guide groove 15 is formed on the front wall portion of the housing portions 11 and 21. Moreover, it is preferable to provide the grip strength sensor 16 in the housing parts 11 and 21.

  Furthermore, as shown in FIG. 14, the specimen information detection unit 7 is provided with light sources 51 and 52 and a second sensor 53 in the casings 11 and 21 to form an oxygen saturation measuring unit. Alternatively, as shown in FIG. 15, the second opening 62 is formed in the housing parts 11 and 21, the second cavity 63 is formed, the synthesis optical system 61 and the third sensor 64 are provided, and blood glucose is provided. A value measuring means is formed. Alternatively, both the oxygen saturation detection unit and the blood glucose level measurement unit may be formed.

  Moreover, it is preferable to provide the signal processing part 101 which processes the signal detected with the 1st sensor 14 and the grip strength sensor 16 in the housing | casing parts 11 and 21 (FIG. 27). Moreover, it is preferable to provide the light emission control part 201 which controls the optical signal emitted from the 2nd light sources 51 and 52 or the synthetic | combination optical system 61 (FIG. 27).

(Signal processing part)
The specimen information detection unit 7 includes a pulsation signal (pulse wave signal) detected by the first sensor 14, a pressing signal regarding the grip strength of the hand detected by the grip strength sensor 16, and the second sensor 53. And a signal processing unit 101 that is an electric circuit that processes information on the oxygen saturation in the blood vessel detected in step 3 and information on vibration caused by the optical signal from the synthesis optical system 31 detected by the third sensor 64. It is preferable (FIG. 27). The signal processing unit 101 includes a polarity determination unit 102, a pressing information detection unit 103, and a pressing optimization unit 104.

(Light emission control unit)
The specimen information detection unit 7 according to the second embodiment of the present invention controls the optical signal emitted from the second light sources 51 and 52 or the combining optical system 61, and the second sensor 53 or the third sensor. It is preferable to include a light emission control unit 201, which is an electronic circuit that controls the signal detected by 64 (FIG. 27). The light emission control unit 201 uses the fact that the pulse wave is stably detected by the first sensor 14 to process the signal at the timing as shown in FIG. 16 to measure the oxygen saturation and the blood glucose level. It is.

<Measurement of oxygen saturation>
As shown in FIG. 14, the oxygen saturation detection means includes a second light source 51, 52, a second sensor 53, a plate-shaped member 54, rod-shaped members 55 a, 55 b, and elastic springs, etc. Members 56a and 56b are provided and formed.

  The second sensor 53 is preferably provided in the housing portions 11 and 21 so as to face the second light sources 51 and 52 and sandwich the finger 91 therebetween. In the present embodiment, as shown in FIG. 14, the housing portions 11 and 21 are provided with a pair of rod-like members 55a and 55b that are provided so as to be able to expand and contract substantially vertically from the front wall portion, and the rod-like members 55a. , 55b is provided with a plate-like member 54 so as to connect the end portion on the opposite side to the casing portion, and the plate-like member 54 is provided with a first sensor 53. The rod-like members 55a and 55b are provided with elastic members 56a and 56b such as springs, respectively, so as to apply an elastic force so as to draw the plate-like member 54 and the first sensor 53 toward the housing portions 11 and 21. It is configured. With this configuration, the specimen finger 91 can be inserted between the plate-like member 54 and the first sensor 53 and the casing 11 and can be held by being sandwiched by elastic force.

  In this way, the oxygen saturation detection means transmits the transmitted light that the optical signal emitted from the second light sources 51 and 52 has passed through the finger 91 with the second sensor 53 and the second light sources 51 and 52 facing each other. Is detected by the second sensor 53 to detect information on the oxygen saturation in the blood vessel of the finger.

  Further, the second light sources 51 and 52 and the second sensor 53 are preferably provided in the vicinity of the end 22 of the guide groove 15. In addition, the second light sources 51 and 52 and the second sensor 53 are formed at a portion facing the tip of the finger, and the first opening 12 or the light transmitting portion 23 is the first joint of the finger 91 of the hand. It is particularly preferable that it is formed at a site to be opposed to the skin portion corresponding to the portion.

(Second light source)
The second light sources 51 and 52 are provided in the housing portions 11 and 21 and generate optical signals so as to pass through the finger 91. The second light sources 51 and 52 are preferably light sources that supply intermittent optical signals. For example, laser diodes (LDs) and LEDs (Light Emitting Diodes) can be used.

  The second light source detects hemoglobin (reduced hemoglobin) that is dissociated from oxygen in response to a change in absorption wavelength due to the binding and dissociation of oxygen in hemoglobin in blood in order to detect information on oxygen saturation in blood vessels. ) And a second wavelength light that increases absorption in oxygenated hemoglobin (oxygenated hemoglobin), and preferably emits the first wavelength light and the second wavelength light. May be composed of two types of light sources (a first second light source 51 and a second second light source 52). Alternatively, the chip may be formed as a chip in which two types of light sources each emitting light of the first wavelength and light of the second wavelength are combined. The wavelength of light generated from the first second light source 51 (first wavelength) can be set to, for example, 650 nm, and the wavelength of light generated from the second second light source (light of the second wavelength). For example, it can be 940 nm.

(Second sensor)
The second sensor 53 is provided in the housing parts 11 and 21 and receives optical signals (transmitted light) from the second light sources 51 and 52 that have passed through the finger 91 and detects information on oxygen saturation in the blood vessel. To do. The second sensor 53 is preferably an optical sensor (light receiving element, optical detector) capable of detecting specific light, and a photodiode such as a PIN photodiode or a PN junction / photodiode can be used.

  The second sensor 53 detects the information on the oxygen saturation in the blood vessel in the same manner as the second light source, corresponding to the change in the absorption wavelength due to the binding and dissociation of oxygen in hemoglobin in the blood. It is preferable to detect the light of the first wavelength and the light of the second wavelength, and it may be composed of two types of sensors that respectively detect the light of the first wavelength and the light of the second wavelength. In the case where 650 nm is used as the first wavelength light and 940 nm is used as the second wavelength light, the detection can be performed by one sensor because the wavelengths are close.

Reduced hemoglobin (Hb) absorbs light near red light, and oxygenated hemoglobin (HbO ₂ ) absorbs light near infrared light. If the output of the transmitted light having the first wavelength (λ1) detected by the second sensor 53 is A (λ1) and the output of the transmitted light having the second wavelength (λ2) is A (λ2), for example, the first wavelength is 650 nm. When the second wavelength is 940 nm, the ratio of reduced hemoglobin to oxygenated hemoglobin in blood can be obtained from the transmitted light ratio of A (λ1) and A (λ2). Furthermore, based on this ratio, the ratio of oxygen in hemoglobin (oxygen saturation) can be calculated.

<Blood glucose measurement means>
As shown in FIG. 15, the blood glucose level measuring means is formed with a second opening 62 in the housing parts 11, 21, a second cavity 63, and a synthetic optical system 61 and a third sensor 64. It is provided and formed.

(Second opening)
The second opening 62 is formed by providing an opening in the front wall portion of the casing 11, 21 facing the sample 95 when the sample information detection unit 7 is attached to the sample 95. The housing portions 11 and 21 of the unit 7 are parts that come into contact with the specimen 95. The casings 11 and 21 are in contact with the specimen 95 so that the second opening 62 is covered with the specimen 95. The second opening 62 communicates with the second cavity 63. Note that an O-ring 66 made of an elastic body such as rubber or silicon may be provided around the second opening 62, and the O-ring 66 may be in contact with the specimen information detection unit 7.

(Second cavity)
The second cavity 63 communicates with the second opening 62 and has a closed space structure in a state where the second opening 62 is opposed to the specimen 95, and is formed in the housing parts 11 and 21. ing. The closed space structure formed by the second cavity 63 in this manner is also referred to as “Closed Cavity”. A third sensor 64 is provided in each of the second cavities 63.

(Synthetic optics)
The synthesis optical system 61 is provided in the housing parts 11 and 21, passes through the second cavity 63 of the housing parts 11 and 21, and passes through the second opening 62 of the housing parts 11 and 21 toward the sample 95. An optical signal is supplied. The combining optical system 61 is configured to receive a signal from the light emission control unit 61 and emit an optical signal.

  The synthesizing optical system 61 includes a plurality of light sources that emit light of individual wavelengths. In the synthesizing optical system 61, the synthesizing optical system 61 produces synthesized light that is synthesized from the light emitted from the plurality of light sources. Be emitted. As shown in FIG. 15, the combined light emitted from the combining optical system 61 is focused by passing through the objective lens, and then irradiated to the specimen 95 through the second cavity 63 and the second opening 62. It is preferable. The synthesis of light from a plurality of light sources can be performed using, for example, a dichroic mirror.

  The light source constituting the combining optical system 61 is preferably a light source that supplies an intermittent optical signal, and for example, a laser diode (LD) or an LED (Light Emitting Diode) can be used. When the combining optical system 61 is a laser diode, it is preferably configured to oscillate pulsed light as a pulse oscillation source.

  As the synthesis optical system 61, a light source that mainly emits light in the infrared region is used. However, it is preferable to select a light source that emits a wavelength of light that is absorbed by a substance to be analyzed included in the specimen 95. When measuring the glucose concentration in the blood vessel, it is preferable to use a light source that supplies an optical signal having a maximum in the absorption wavelength of the C—H group or O—H group of the glucose molecule. The light in the infrared region may include wavelengths in the near infrared region.

  For the synthesis optical system 61, it is preferable to use a light source that emits visible light in addition to the light source that emits the wavelength of light that is absorbed by the substance to be analyzed, and the light emitted from all these light sources is synthesized. It is preferable to irradiate the specimen 95. By using a light source that emits visible light in the combining optical system 61, the position of the spot illuminated on the specimen 95 by the irradiation of visible light is used as the irradiation position of the optical signal by the combining optical system 61. ). The visible light may be constantly turned on, or it may be turned on when light in the infrared region is not emitted in order to position the irradiation position by the specimen information detection unit 7.

In addition, in the synthetic optical system 61 of this embodiment, in order to measure the glucose concentration (blood glucose level) in the blood, light of six wavelengths of λ _{3 to} λ ₈ which is a part of near infrared light is used. A light source that emits light and a light source that emits light having a wavelength of red λ _{9 in} the visible light region are used. Further, in the present embodiment, since the light collecting performance of the objective lens is not so necessary, the light is condensed by combining six wavelengths from λ ₃ to λ ₈ . Of course, since the transmittance for each wavelength of the objective lens is different, it is necessary to convert it with the output signal of the light source according to the transmittance.

  The synthetic optical system 61 is preferably provided so as to face the second opening 62 in the housing portions 11 and 21 in order to make an optical signal act effectively on a blood vessel directly under the skin of the specimen 95. The combining optical system 61 is preferably provided so that the optical signal supply direction from the combining optical system 61 is incident on the second opening 62 and the specimen 95 from the vertical direction.

(Third sensor)
As the third sensor 64, a photoacoustic spectroscopic analysis can be performed by detecting a signal caused by the light emitted from the synthesis optical system 61 (a signal emitted in response to the optical signal emitted from the synthesis optical system 61). Although it is not particularly limited as long as it is a sensor, the vibration of the air caused by the vibration of the skin of the specimen 95 caused by the optical signal from the synthesis optical system 61 is used as a signal caused by the light emitted from the synthesis optical system 61. A microphone that electrically detects (sound pressure information) can be preferably used. Among the microphones, a condenser microphone is preferable in terms of directivity, S / N ratio, and sensitivity, and an ECM (electret condenser microphone; hereinafter, also simply referred to as “ECM”) can be suitably used. In addition, a MEMS ECM (hereinafter, also referred to as “MEMS-ECM”), which is an ECM manufactured using a microelectromechanical system (MEMS) technique, can be preferably used.

  In the present embodiment, a configuration in which two third sensors 64 a and 64 b are provided in the casing portions 11 and 21 of the sample information detection unit 7 is described. The number of the third sensors provided in the housing parts 11 and 21 may be one or more. However, from the viewpoint of improving the strength of the detected signal and increasing the S / N ratio, the third sensor Preferably, two or more are provided, and the sum of the signals of the third sensors is preferably used as a signal output resulting from the optical signal from the combining optical system 61.

  In the case where the third sensor 64 is provided in the specimen information detection unit 7, it is preferable that the third sensor 64 is provided in a part where the influence of the optical signal from the synthesis optical system 61 in the housing parts 11 and 21 can be avoided. Thereby, it is possible to improve the strength of the detected pulsation signal and increase the S / N ratio while avoiding the influence of the optical signal from the synthesis optical system 61.

  When the third sensor 64 is provided in the specimen information detection unit 7, the MEMS-ECM is preferable because it is small in size and can be easily mounted and the diameter of the second opening 62 can be prevented from becoming too large. In addition, since the quality of the MEMS-ECM is stable, a stable signal can be obtained even when a plurality of third sensors 41 are connected in parallel and the signals of the third sensors 41 are added. Therefore, it is preferable.

[3-2. Functional configuration of specimen information detection unit according to second embodiment]
When an example of the sample information detection unit 7 according to the second embodiment of the present invention is functionally represented, the sample information detection unit 7 includes a first sensor 14, a grip strength sensor 16, a polarity notification as shown in FIG. Unit 25, grip strength notification unit 26, sample detection sensor 27, sample notification unit 28, storage unit 29, clock 42, GPS antenna 43, GPS processing circuit 44, body temperature detection unit 45, outside air temperature detection unit 46, storage battery 47, the second light sources 51 and 52, the second sensor 53, the combining optical system 61, the third sensor 64, the signal processing unit 101, and the light emission control unit 201. The signal processing unit 101 includes the polarity determination unit 102, the pressing information. A detection unit 103 and a press optimization unit 104 are included.

  The first sensor 14 detects pressure information or an optical signal resulting from the pulsation signal, the grip strength sensor 16 detects pressure information resulting from the grip strength, and the first sensor 14 and the grip strength sensor. The signal detected in 16 is sent to the signal processing unit 101, and the signal is processed by the polarity determination unit 102, the pressing information detection unit 103, and the pressing optimization unit 104. In addition, upon receiving a signal from the signal processing unit, an optical signal is emitted from the second light sources 51 and 52 and the combining optical system 61 under the control of the light emission control unit 201, and the second sensor 53 is transmitted from the second light sources 51 and 52. The transmitted light of the optical signal is detected, the third sensor 64 detects a signal emitted due to the optical signal from the combining optical system 61, and the signals detected by the second sensor 53 and the third sensor 64 emit light. It is configured to be sent to the control unit 201 for processing.

[3-3. Operation of Specimen Information Detection Unit According to Second Embodiment]
Below, an example of operation | movement of the sample information detection unit 7 concerning 2nd embodiment of this invention is demonstrated.

<Detection of pulsation signal and pressing force>
In the same manner as the morphological information detection unit 1 according to the first embodiment, the fingertip is such that the abdomen 92 of the finger between the tip of the fingertip of the sample finger 91 and the first joint is in contact with the first opening 12. The housing portions 11 and 21 are gripped by hand so that the first cavity 13 is closed to form a closed space structure (closed cavity). In this state, the first sensor 14 provided in the first opening 12 detects a micro blood vessel at the fingertip or a pulse wave (pulsation signal) in the capillary blood vessel as pressure information. Further, the grip strength sensor 16 provided in the peripheral portion of the first opening 12 detects the grip strength of the hand as a pressing force (press signal) for pressing the grip strength sensor 16 with a finger.

<Detection of oxygen saturation information and calculation of oxygen saturation>
As shown in FIG. 14, the first second light source 51 and the second second light source 52 are located on the abdomen portion 92 of the fingertip, the second sensor 53 is located on the nail portion 93 of the fingertip, The second light source 51, the second second light source 52, and the second sensor 53 are arranged so as to face each other with the finger 91 interposed therebetween, and the sample information detection unit 7 is attached to the sample finger 91. In this state, an optical signal is generated from the first second light source 51 and the second second light source 52 of the specimen information detection unit 7 so as to pass through the finger, and the first second light source 51 is generated by the second sensor 53. And the optical signal from the 2nd 2nd light source 52 is received, the information regarding the oxygen saturation in a blood vessel is detected, and oxygen saturation can be calculated. . That is, the first second light source 51, the second second light source 52, and the second sensor 53 function as a pulse oximeter.

  The oxygen saturation may be calculated by a signal processing unit provided in the specimen information detection unit. The signal obtained from the second sensor 53 is stored in the storage unit 29 and stored in the storage unit 29. To an external computer, and signal processing may be performed by the external computer.

<Calculation of blood glucose level>
As shown in FIG. 15, the specimen information detection unit 7 is mounted so that the specimen 95 can be irradiated with the optical signal from the synthesis optical system 61. The specimen 95 is preferably a part that can irradiate a blood vessel with an optical signal from the synthesis optical system 61, and for example, a palm can be suitably used. At this time, it is preferable to perform measurement by grasping the specimen information detection unit 7 by hand. When an optical signal is generated from the synthesis optical system 61 of the specimen information detection unit 7 in this state, a substance in the blood vessel in the specimen 95 is affected by the optical signal from the synthesis optical system 61, and vibration caused by a response by this optical signal. Propagates in the second cavity 63 through the second opening 62 as pressure information. This pressure information can be detected by the third sensor 64 to calculate the blood sugar level. Thus, the blood glucose level can be calculated by using non-invasive photoacoustic spectroscopy.

  The blood glucose level may be calculated by a signal processing unit provided in the sample information detection unit. The signal obtained from the third sensor 64 is stored in the storage unit 29 and is stored in the storage unit 29. It may be transmitted to an external computer and signal processing may be performed by the external computer.

<Control of signal by light emission control unit>
The light emission control unit 201 emits a first second light source 51 that emits light having a wavelength of λ ₁ , a second second light source 52 that emits light having a wavelength of λ ₂ , and light having a wavelength of λ _{3 to} λ _8. The output of light from the combining optical system 61 and the detection of signals by the second sensor 53 and the third sensor 64 are preferably controlled as in the timing chart shown in FIG.

  The specimen information detection unit 7 according to the second embodiment of the present invention uses the fact that the pulse wave is detected by the first sensor 14 to process the signal at the timing as shown in FIG. Measure the blood glucose level.

  As shown in FIG. 16A, the pulse wave signal detected by the first sensor is one period detected in the pulse wave signal, with one period from the rise of the pulse wave signal to the rise of the next pulse wave signal. Is divided into 1024 timings and divided into a total of 1024 timings from 0 to 1023 in one cycle. Control is performed according to the timing based on one cycle of the pulse wave.

  First, by using FIGS. 16B1 to 16B8, the output of the optical signals from the first second light source 51 and the second second light source 52 when measuring the oxygen saturation, and the second sensor Control of signal detection by 53 will be described.

As shown in FIG. 16 (b1), the light λ ₁ On having the wavelength λ ₁ is emitted from the first second light source 51 (here, the LED) at the timing of 882. Upon receiving the light emitted from the first second light source 51, the second sensor 53 determines the amount of transmitted light of the wavelength λ ₁ from the first second light source at the timing of 882 as shown in FIG. 16 (b3). Detection is performed as a signal A _{1 having} a waveform of a light transmission signal of λ _{1, and} the detected signal A ₁ is sent to the light emission control unit 201. Next, as shown in FIG. 16B5, the light emission control unit 201 outputs the sampling pulse λ ₁ S of the light transmission signal of λ ₁ at the timing of 883. In response to the sampling pulses lambda ₁ S, at the timing of 883, as shown in FIG. 16 (b7), that signal A ₁ of the waveform of lambda ₁ of the light transmission signal is sampled and held, lambda ₁ of the light transmission signal The sampling result λ ₁ A is output from the light emission control unit 201 to calculate the oxygen saturation as a signal representing the amount of transmitted light of wavelength λ ₁ from the first second light source.

On the other hand, as shown in FIG. 16 (b2), light λ ₂ On having wavelength λ ₂ is emitted from the second second light source 52 (here, LED) at the timing 883. Upon receiving the light emitted from the second second light source 52, the second sensor 53 determines the amount of transmitted light of wavelength λ ₂ from the second second light source at the timing 883 as shown in FIG. 16 (b4). The signal A ₂ is detected as a signal A _{2 having} a waveform of a light transmission signal of λ _{2, and} the detected signal A ₂ is sent to the light emission control unit 201. Next, as shown in FIG. 16B6, the light emission control unit 201 outputs the sampling pulse λ ₂ S of the light transmission signal of λ ₂ at the timing of 884. In response to the sampling pulse lambda ₂ S, at the timing of 884, as shown in FIG. 16 (b8), that the signal A ₂ of the waveform of the lambda ₂ light transmission signal is sampled and held, lambda ₂ of the optical transmission signal The sampling result λ ₂ A is output from the light emission control unit 201 for calculation of the oxygen saturation as a signal representing the amount of transmitted light of wavelength λ ₂ from the second second light source.

As described above, the optical signal output from the first second light source 51 and the second second light source 52 and the signal detection by the second sensor 53 are controlled, and each pulse wave is held as one value. Thus, the amount of transmitted light of the wavelength λ ₁ from the first second light source and the amount of transmitted light of the wavelength λ ₂ from the second second light source are measured to measure the oxygen saturation. it can.

  Next, the output of the optical signal from the synthesis optical system 61 and the detection of the signal by the third sensor 64 at the time of measuring the blood glucose level will be described with reference to FIGS.

In 884 the timing of, as shown in FIG. 16 (c1), the wavelength lambda ₃ of the light lambda ₃ On a light source emitting light of wavelength lambda ₃ of the combining optical system 61 (LD here) is emitted. Receiving light emission from the combining optical system 61, at the timing of 884, as shown in FIG. 16 (c7), signals of lambda ₃ to the third sensor 64 is due to an optical signal of wavelength lambda ₃ from the combining optical system 61 The detected signal A ₃ is detected as a signal A _{3 having} a waveform of an optical signal, and the detected signal A ₃ is sent to the light emission control unit 201. Next, as shown in FIG. 16 (c13), the light emission control unit 201 outputs a sampling pulse λ ₃ S of a signal resulting from the optical signal of λ ₃ at the timing of 885. In response to the sampling pulse lambda ₃ S, at the timing of 885, as shown in FIG. 16 (b19), that the signal A ₃ of the waveform of lambda ₃ of the optical signal is sampled and held, due to lambda ₃ of the optical signal The signal sampling result λ ₃ A is output from the light emission control unit 201 to calculate the blood sugar level as a signal resulting from the optical signal having the wavelength λ ₃ from the combining optical system 61.

The light source that emits light of wavelengths λ _{4 to} λ ₈ of the combining optical system 61 and the third sensor 64 are also the same as the light source that emits light of wavelength λ ₃ of the combining optical system 61 and the third sensor 64 described above. FIG 16 (c2) ~ (c6) , (c8) , as shown in ~ (c12), the emission timing of the light source emitting light of wavelength lambda _3, the light emission from each light source 885,886,887,888 performed by shifting one by 889 and 1, and FIG. 16 (c14) ~ (c18) , (c20) , as shown in ~ (c24), the timing of the sample hold of the signal due to the optical signal of the wavelength lambda ₃ The sampling hold by the third sensor 64 for the signals resulting from the optical signals of the respective wavelengths is controlled by shifting the timing by 1 from 886, 887, 888, 889, 890, and each pulse wave is controlled. By holding a one value, it is possible to measure the blood glucose level a signal resulting from the optical signal of the wavelength lambda ₄ to [lambda] ₈ of combining optical system 61 were measured.

  In the above description, an example has been given in which an optical signal is generated at a timing of 802 to 809 and the control is sequentially performed. However, if the timing can avoid the influence of pulsation of a pulse wave, It can be performed at any timing. Immediately after the peak of the velocity pulse wave rises, the influence of the pulsation on the calculation of the oxygen saturation is large, and therefore the timing at which the fluctuation of the velocity pulse wave is small during one cycle from the rise of the peak to the rise of the next peak. Thus, it is preferable to perform signal processing with the same phase. Further, the signal processing may be performed at a timing at which the fluctuation of the velocity pulse wave is small during one cycle from the rising edge of the peak to the rising edge of the next peak with reference to the timing of outputting the sampling pulse.

  In the above description, an example in which one period is divided into 1024 with one period from the rising edge of the peak to the rising edge of the next peak is not limited thereto, and signal processing is performed by dividing the period into an arbitrary number. Good.

  By processing the above signals, the influence of the pulse wave can be reduced by sampling at the same phase with respect to the blood flow (pulse wave), and the influence of the pulse wave is reduced in the calculation of oxygen saturation and blood sugar level. can do. That is, by generating timing based on the pulsation signal detected by the first sensor 14 and controlling the generation timing of the optical signal from the light source and the sampling timing by the sensor, the calculation of oxygen saturation and blood glucose level is performed. The influence of the pulse wave can be reduced. Further, by controlling the output of the optical signal from the light source and the timing of detection by the sensor, the signal can be detected by one sensor for a plurality of light sources.

Signals of the transmitted light amount of light of wavelength λ ₁ from the first second light source and the transmitted light amount of light of wavelength λ ₂ from the second second light source, and wavelengths λ _{3 to} λ, measured by the light emission control unit The signal resulting from the optical signal of ₈ may be provided with a calculation unit for processing the signals by the specimen information detection unit 7 to calculate the oxygen saturation level and the blood glucose level, or these signals may be externally transmitted. It may be sent to a computer and the oxygen saturation and blood glucose level may be calculated by an external computer.

[3-4. Application example of sample information detection unit according to second embodiment]
The specimen information detection unit 7 according to the second embodiment of the present invention can be applied to an electric appliance having a grip portion such as an electric shaver device or an electric toothbrush device.
At this time, the cradle 2 in the specimen information detection unit 7 may also serve as an electric shaver device or an electric toothbrush device cradle.

[3-5. Effect of specimen information detection unit according to second embodiment]
According to the specimen information detection unit 7 according to the second embodiment of the present invention, in addition to the effects obtained in the first embodiment, the first sensor 14, the second light sources 51 and 52, the second sensor 53, By providing the pulse wave, it is possible to obtain a pulse wave and measure the oxygen saturation. In addition, by providing the first sensor 14, the synthesis optical system 61, the second opening 62, the second cavity 63, and the third sensor 64, it is possible to obtain a pulse wave and measure a blood sugar level. Become. Furthermore, by generating timing from the pulsation signal detected by the first sensor 21 and controlling the signal, the influence of the pulse wave in the measurement of oxygen saturation and blood glucose level can be reduced.

[B2. Description of First Modification of Second Embodiment]
[4. Sample Information Detection Unit According to First Modification of Second Embodiment]
[4-1. Sample configuration of specimen information detection unit]
Here, the sample information detection unit according to the first modification of the second embodiment of the present invention will be described as an example in which the first modification is applied to the second embodiment described above.

  The sample information detection unit according to the first modification of the second embodiment is configured in the same manner as the second embodiment described above or the first modification of the first embodiment except for a part of the configuration. The description of the same sample information processing detection unit will be omitted, and will be described using the same reference numerals.

<Configuration of specimen information detection unit>
The sample information detection unit 8 according to the first modification of the second embodiment of the present invention is, as an example, shown in FIGS. 12 (a), 12 (b), 21 (a), and 21 (b). In addition, the housing portions 31 and 41 are provided, the housing portion 11 is configured as a cylindrical member, and functions as a plurality of pressure-sensitive elements 38a to 38c or first sensors 34a to 34c that function as the first sensors 34a to 34c. A plurality of light receiving elements 78a to 78c are provided.

  As shown in FIGS. 12A and 12B, the specimen information detection unit 8 according to the first modification of the second embodiment of the present invention includes a plurality of first openings in the casing portions 31 and 41. The portions 32a to 32c are formed, a plurality of first cavities 33a to 33c are formed, and a plurality of pressure sensitive elements 38a to 38c functioning as the first sensors 34a to 34c are provided. Alternatively, the specimen information detection unit 8 according to the first modification of the second embodiment of the present invention includes a plurality of second housings 31 and 41 as shown in FIGS. 21 (a) and 21 (b). 1 light source 77a-77c, light transmission part 73a-c, and the some light receiving element 78a-78c which functions as 1st sensor 34a-34c are provided.

  Moreover, the specimen information detection unit 8 according to the first modification of the second embodiment of the present invention is as shown in FIGS. 12 (a), 12 (b), 21 (a), and 21 (b). It is preferable that a plurality of finger guide grooves 35 a to 35 c are formed on the front wall portions of the casing portions 31 and 41. Moreover, it is preferable that the casing units 31 and 41 have grip strength sensors 36a to 36c.

  Further, as shown in FIG. 14, the specimen information detection unit 8 is provided with second light sources 51 and 52 and a second sensor 53 in the casing portions 31 and 41 to form oxygen saturation measuring means. As shown in FIG. 15, the second openings 62 are formed in the casings 31 and 41, the second cavity 63 is formed, and the synthesis optical system 61 and the third sensor 64 are provided. Thus, blood glucose level measuring means is formed. Alternatively, both oxygen saturation detection means and blood glucose level measurement means may be formed.

  Moreover, it is preferable that the housing units 31 and 41 include a signal processing unit 101 that processes signals detected by the first sensors 34 a to 34 c and the grip strength sensor 16. Moreover, it is preferable to provide the light emission control part 201 which controls the optical signal emitted from the 2nd light sources 51 and 52 or the synthetic | combination optical system 61 (FIG. 28).

[4-2. Functional Configuration of Specimen Information Detection Unit According to First Modification of Second Embodiment]
When the sample information detection unit 8 according to the first modification of the second embodiment of the present invention is functionally represented, the sample information detection unit 8 includes first sensors 34a to 34c, grip strength as shown in FIG. Sensors 36a to 36c, polarity notification unit 25, grip strength notification unit 26, sample detection sensor 27, sample notification unit 28, storage unit 29, clock 42, GPS antenna 43, GPS processing circuit 44, body temperature detection unit 45, The outside air temperature detecting means 46, the storage battery 47, the second light sources 51 and 52, the second sensor 53, the combining optical system 61, the third sensor 64, the signal processing unit 101, and the light emission control unit 201 are provided. A polarity determination unit 102, a pressing information detection unit 103, a pressing optimization unit 104, and an averaging processing unit 105 are included.

  The first sensor 34a to 34c detects pressure information or optical signal due to the pulsation signal, the grip strength sensors 36a to 36c detect pressure information due to the grip strength, and the first sensor 34a to 34c. 34c and the grip strength sensors 36a to 36c are transmitted to the signal processing unit 101, and the signals are processed by the polarity determination unit 102, the press information detection unit 103, the press optimization unit 104, and the averaging processing unit 105. It is configured to In addition, upon receiving a signal from the signal processing unit, an optical signal is emitted from the second light sources 51 and 52 and the combining optical system 61 under the control of the light emission control unit 201, and the second sensor 53 is transmitted from the second light sources 51 and 52. The transmitted light of the optical signal is detected, the third sensor 64 detects a signal emitted due to the optical signal from the combining optical system 61, and the signals detected by the second sensor 53 and the third sensor 64 emit light. It is configured to be sent to the control unit 201 for processing.

[4-3. Operation of Specimen Information Detection Unit According to First Modification of Second Embodiment]
Below, an example of operation | movement of the sample information detection unit 8 concerning 2nd embodiment of this invention is demonstrated.

<Detection of pulsation signal and pressing force>
Similar to the sample information detection unit 5 according to the first modification of the first embodiment, the first openings 32a to 32c are in contact with the first joints from the tips of the plurality of fingertips of the sample hand. As described above, the casings 31 and 41 are held by hand so that the fingertips are pressed against each other, thereby forming a space structure (closed cavity) in which the first cavities 33a to 33c are closed. In this state, the first sensors 34a to 34c provided in the first openings 32a to 32c respectively generate pulsation waves (pulsation signals) in the fine blood vessels, capillaries, or arterial blood vessels existing in the joint portions at a plurality of fingertips. Detect as pressure information. Further, the grip strength sensors 36a to 36c provided in the peripheral portions of the first openings 32a to 32c are used to determine the grip strength of the hand with the respective fingers to press the grip strength sensor 16 (press signal). Detect as.

<Processing of multiple pulsatile signals>
Similar to the specimen information detection unit 5 according to the first modification of the first embodiment, an averaged pulse wave signal and an averaged pressure signal are obtained.

<Detection of oxygen saturation information and calculation of oxygen saturation>
In the same manner as the specimen information detection unit 7 of the second embodiment, optical signals from the second light source 51 and the second second light source 52 are received by the second sensor 53 and information relating to oxygen saturation in the blood vessel is detected. Thus, the oxygen saturation can be calculated.

<Calculation of blood glucose level>
Similar to the sample information detection unit 7 of the second embodiment, the blood pressure level can be calculated by detecting the pressure information caused by the optical signal from the synthesis optical system 61 by the third sensor 64.

<Control of signal by light emission control unit>
Similarly to the sample information detection unit 7 of the second embodiment, the light emission control unit 201 causes the transmitted light amount of the light with the wavelength λ ₁ from the first second light source and the wavelength λ ₂ from the second second light source. The amount of transmitted light can be measured to measure oxygen saturation. In addition, the blood glucose level can be measured by measuring signals caused by the optical signals of the wavelengths λ _{3 to} λ ₈ of the synthesis optical system 61.

[4-4. Application Example of Specimen Information Detection Unit According to First Modification of Second Embodiment]
The sample information detection unit 8 according to the first modification of the second embodiment of the present invention can be applied to an electric appliance having a grip portion such as an electric shaver device or an electric toothbrush device.
At this time, the cradle 2 in the specimen information detection unit 8 may also serve as an electric shaver device or an electric toothbrush device cradle.

[4-5. Effect of specimen information detection unit according to second modification of second embodiment]
According to the specimen information detection unit 8 according to the first modification of the second embodiment of the present invention, the effects obtained in the first embodiment, the first modification of the first embodiment, and the second embodiment. In addition, the pulsation signal becomes accurate by obtaining the averaged pulsation signal from the pulsation signals detected by the plurality of first sensors 34a to 34c, so that more actual pulsation waves can be obtained in the light emission control. Therefore, the influence of the pulse wave on the calculation of the oxygen saturation and the blood glucose level can be further reduced.

[Others]
In the above description, the processing of the pulsation signal and the pressure signal by the analog circuit included in the sample information detection unit has been described. However, the sample information detection unit is also a digital circuit, for example, a digital signal processor (hereinafter also referred to as “DSP”). ), And digitally process the signal using this digital circuit.

  Further, signals detected by the first sensor, the grip strength sensor, the second sensor, and the third sensor are output to a computer via an A / D converter outside the specimen information detection unit, and the signal is processed by the CPU. It is good also as a structure.

1, 3, 5, 6, 7, 8, 9, 81, 82 Sample information detection unit 2 Cradle 11, 21, 31, 41 Case 12, 32a-32c First opening 13, 33a-33c First cavity 14, 34a to 34c First sensor 15, 35a to 35c Guide groove 16, 36a to 36c Grip strength sensor 22, 37a to 37c End portion of guide groove 51, 52 Second light source 53 Second sensor 61 Composite optical system 64 First Three sensors 91 Finger 101 Signal processing unit 102 Polarity determination unit 103 Press information detection unit 104 Press optimization unit 201 Light emission control unit

Claims (25)

Provide a housing with an external shape that can be grasped by the hand of the specimen,
The casing is configured as a columnar member or egg-shaped member,
A specimen information detection unit provided with a first sensor that is provided in the casing and detects a pulsation signal of a blood vessel in a finger of the hand that holds the casing. A first opening having a diameter of 3 mm to 8 mm is formed in a portion of the casing that should be opposed to the finger of the hand that grips the casing,
A first cavity that is in communication with the first opening and that is closed in a state where the first opening is opposed to the finger and the case is held by the hand is formed in the case. Formed,
The first sensor detects a pulsation signal of a blood vessel in the finger inputted through the first opening as pressure information propagating in the first cavity due to the pulsation signal. The specimen information detection unit according to claim 1. A guide groove for the finger is formed on the front wall portion of the housing portion,
The specimen information detection unit according to claim 2, wherein the opening is formed in the guide groove. A first light source that is provided in the housing and generates an optical signal toward the finger of the hand that grips the housing;
A light transmissive portion provided at a portion of the housing portion that should be opposed to the finger of the hand that grips the housing portion, and made of a transmissive material capable of transmitting an optical signal from the first light source;
A finger of a hand that grips the casing portion faces the light transmitting portion provided in the casing portion, and an optical signal from the first light source passes through the light transmitting portion and hits the finger. A light signal reflected upon the light is transmitted through the light transmission part and detected by the first sensor,
The first sensor detects a pulsation signal of a blood vessel in the finger by receiving an optical signal reflected by the light signal from the first light source caused by the pulsation signal and hitting the finger. The specimen information detection unit according to claim 1. A guide groove for the finger is formed on the front wall portion of the housing portion,
The specimen information detection unit according to claim 4, wherein the light transmission part is provided in the guide groove. Provide a housing with an external shape that can be grasped by the hand of the specimen,
The casing is configured as a columnar member or egg-shaped member,
Specimen information detection unit provided with a plurality of first sensors provided in the casing for detecting pulsation signals of blood vessels in a plurality of fingers of the hand gripping the casing . A first opening having a diameter of 3 mm to 8 mm is formed in each part of the casing that should be opposed to each finger of the hand that has gripped the casing,
A plurality of first structures that communicate with each of the first openings and that are closed in a state in which the first openings are opposed to the respective fingers and the case is held by the hand. 1 cavity is formed in the housing,
The first sensor detects a pulsation signal of a blood vessel in each finger inputted through each first opening as pressure information propagating in each first cavity due to the pulsation signal. The specimen information detection unit according to claim 6, wherein: The guide groove of each finger is formed on the front wall portion of the housing portion,
8. The specimen information detection unit according to claim 7, wherein the opening is formed in each guide groove. A plurality of first light sources that are provided in the housing unit and generate optical signals toward the fingers of the hand that grips the housing unit;
A plurality of lights made of a transmissive material that is provided at a portion of the casing portion that should be opposed to each finger of the hand that holds the casing portion and can transmit an optical signal from the first light source. With a transmission part,
A plurality of fingers of the hand holding the casing face the respective light transmitting portions provided in the respective guide grooves, and light signals from the respective first light sources receive the respective light. The optical signal is transmitted through the transmission part and hits each finger, and the optical signal reflected by the finger is transmitted through the respective light transmission part and detected by each of the first sensors.
Each of the first sensors receives a pulsation signal of a blood vessel in each finger, and receives an optical signal reflected by the light signal from each of the first light sources resulting from the pulsation signal. The specimen information detection unit according to claim 6, wherein the specimen information detection unit is detected. The guide groove of each finger is formed on the front wall portion of the housing portion,
The specimen information detection unit according to claim 9, wherein the first sensor is provided in each guide groove.   The specimen information detection unit according to any one of claims 2, 3, 7, and 8, wherein the first sensor is a condenser microphone or a PZT piezoelectric element.   The specimen information detection unit according to any one of claims 4, 5, 9, and 10, wherein the first sensor is a photodiode. In the housing part,
In addition to having a sample sensor,
2. A sample notifying unit for notifying a position of the housing unit due to an output from the sample detecting sensor when the sample is detected by the sample detecting sensor. The specimen information detection unit according to claim 12. A polarity determining means for detecting the polarity of the waveform of the pulsating signal detected by the first sensor;
The specimen information detection unit according to any one of claims 1 to 13, further comprising a polarity notification unit that notifies a change in polarity due to an output from the polarity determination means. In the housing part,
With a grip strength sensor that detects the grip strength of the hand,
The grip strength notifying unit for notifying the grip strength of the hand due to the output from the grip strength sensor is provided. The specimen information detection unit described. In the housing part,
The specimen information detection unit according to any one of claims 1 to 15, further comprising storage means for storing a measurement result obtained by the first sensor. In the housing part,
With clock and GPS,
17. The specimen information detection unit according to claim 16, wherein the storage means stores the measurement result of the clock and the GPS and the measurement result of the first sensor in association with each other. In the housing part,
A sample temperature detecting means for detecting the temperature of the sample through the hand holding the casing;
An outside air temperature detecting means for detecting the outside air temperature;
The sample information detection unit according to any one of claims 1 to 17, further comprising storage means for storing measurement results of the sample temperature detection means and the outside air temperature detection means clock. . A second light source provided in the casing and generating an optical signal so as to pass through the finger;
A second sensor that is provided in the casing and receives the optical signal from the light source transmitted through the finger and detects information on oxygen saturation in the blood vessel; The specimen information detection unit according to any one of claims 1 to 18. Having a second opening at a portion of the casing that faces the specimen;
A second cavity is formed in the casing portion that communicates with the opening and has a spatial structure closed with the second opening facing the sample and attached to the sample.
A plurality of light sources that are provided in the casing and supply optical signals to the blood vessels of the specimen through the second opening of the casing through the second cavity of the casing; A synthetic optical system;
A third sensor for receiving a signal from the blood vessel in the specimen affected by the optical signal as pressure information propagating in the second cavity and detecting information on a blood glucose level in the blood vessel; The specimen information detection unit according to any one of claims 1 to 19, wherein the specimen information detection unit is provided.   21. A cradle having a function of reading a measurement signal from the casing and supplying power is provided by mounting the casing in a contact state or a non-contact state. The specimen information detection unit according to any one of the above. An electric toothbrush device,
The electric toothbrush device, wherein the casing portion in the sample information detection unit according to any one of claims 1 to 21 is used as a grip portion of the electric toothbrush device.   The electric toothbrush device according to claim 22, wherein the cradle also serves as a cradle for the electric toothbrush device. An electric shaver device,
The electric shaver device according to any one of claims 1 to 21, wherein the casing portion in the specimen information detection unit according to any one of claims 1 to 21 is used as a grip portion of the electric shaver device.   25. The electric shaver device according to claim 24, wherein the cradle also serves as a cradle for the electric shaver device.

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