JP5578100B2 - Pulse wave measuring device and program - Google Patents

Pulse wave measuring device and program Download PDF

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JP5578100B2
JP5578100B2 JP2011024685A JP2011024685A JP5578100B2 JP 5578100 B2 JP5578100 B2 JP 5578100B2 JP 2011024685 A JP2011024685 A JP 2011024685A JP 2011024685 A JP2011024685 A JP 2011024685A JP 5578100 B2 JP5578100 B2 JP 5578100B2
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signal
measurement site
light
pulse wave
posture
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JP2012161507A (en
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宇 谷
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セイコーエプソン株式会社
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Description

  The present invention relates to a technique for optically measuring a pulse wave.

  A waveform indicating a change in volume of a blood vessel caused by the inflow of blood into a blood vessel in a certain part of the body is called a pulse wave. The undulation of the amplitude in the pulse wave is not exactly the same as the undulation of the amplitude in the electrocardiogram waveform, but has the same periodicity. For this reason, in the diagnosis of heart disease, a pulse meter is attached to the patient's body and the pulse wave is measured, and the pulse interval that appears as a peak in this pulse wave is the interval between the delivery of blood from the left ventricle of the heart to the aorta A simple diagnostic method is widely adopted in which the patient is diagnosed as an electrocardiographic RR interval (hereinafter simply referred to as an RR interval).

  Some pulsometers used for this type of diagnosis have a shape simulating a wristwatch and are used by being worn on the subject's hand. Such a watch-type pulse meter is suitable for monitoring a subject's pulse wave over a long period of time. However, in a wristwatch-type pulse meter, when a subject wears a pulse meter and performs body movement such as walking, noise due to the influence of the body movement is mixed in the pulse wave measurement signal, and the S / N is reduced. May decrease.

 Patent Document 1 discloses a technique for removing noise caused by such body movement from a pulse wave measurement signal. The pulsometer disclosed in this document includes a device main body mounted on the wrist of the subject, a sensor module mounted on the subject's finger as a measurement site, and a cable connecting them. The sensor module has both a pulse wave sensor and a pressure sensor. The pulse wave sensor irradiates light toward the measurement site, converts the reflected light into an electric signal, and sends the electric signal to the apparatus main body as a signal indicating the pulse wave of the subject. The pressure sensor converts the pressure on the body surface of the measurement site into an electrical signal, and sends this electrical signal to the apparatus body as a signal indicating the pressure on the body surface of the measurement site. The main body of the device generates a signal that simulates the noise due to the influence of body movement by applying an adaptive filter process to the output signal of the pressure sensor, and subtracts this signal from the output signal of the pulse wave sensor. Is generated. Then, the signal from which the noise is removed is used as a measurement target signal, and the interval between peaks appearing in this signal is measured as a pulse interval and presented to the subject.

JP 2010-17602 A

  However, in the technique of Patent Document 1, when the finger is congested, for example, when the subject continues to take a posture in which the finger that is the measurement site is positioned below the heart of the subject, noise removal is performed by adaptive filter processing. There is a problem that the pulse interval obtained from the signal deviates from the RR interval that is the original diagnosis target.

  The present invention has been made in view of such a problem, and it is a solution to obtain a measurement result with high accuracy regardless of the congestion of the measurement site in the body of the subject who measures the pulse wave. And

  In order to solve the above-mentioned problem, the present invention is a means attached to a body part of a subject, irradiates light toward the measurement part of the subject's body, and at the measurement part among the irradiated light Light detection means for receiving reflected light or light transmitted through the measurement site and outputting a signal indicating the received light intensity of the received light; together with the light detection means or the light detection means, the body of the subject A physical quantity indicating the posture of the wearing part of the body of the subject of the device to be worn is detected, posture detecting means for outputting a signal indicating the detected physical quantity, and an acceleration generated according to the force applied to the measurement part are detected. , Determining whether the measurement site is congested from the acceleration detection means for outputting a signal indicating the detected acceleration and the output signal of the posture detection means, and determining that the measurement site is congested In addition, an estimated waveform of noise superimposed on the output signal of the light detection means is generated based on the output signal of the acceleration detection means, and the estimated waveform of noise is removed from the output signal of the light detection means. There is provided a pulse wave measuring device comprising processing means for generating a pulse wave signal.

  In this pulse wave measuring device, when the measurement site is congested, an estimated waveform of noise generated using the output signal of the acceleration detection unit is subtracted from the output signal of the light detection unit, and the subtraction result is subtracted from the measurement site. A pulse wave signal indicating a pulse wave is used. Then, through the subtraction of the estimated waveform, noise due to the influence of body movement is removed from the output signal of the light detection means. Therefore, according to the present invention, when the measurement site is congested, the situation in which the peak interval appearing in the output signal of the light detection means does not deviate from the RR interval that is the original measurement target does not occur. Therefore, according to the present invention, a measurement result with high accuracy can be obtained regardless of the presence or absence of congestion at the measurement site.

  In the above-described pulse wave measurement device, when it is determined that the measurement site is congested, the output signal of the acceleration detection signal is subjected to filter processing using a filter coefficient, and the signal after the filter processing is detected by the light detection The subtraction result may be subtracted from the output signal, and adaptive filter processing may be performed to update the filter coefficient used in the filter processing so that the subtraction result decreases, and the subtraction result may be generated as the pulse wave signal. According to this, in the adaptive filter process, the filter coefficient sequence used for the filter process is successively updated so as to simulate the transfer function from the body motion that is the source of noise to the measurement site. Therefore, an estimated noise waveform can be generated efficiently.

  In the above-described pulse wave measurement apparatus, the apparatus includes a storage unit that stores a type of posture that increases congestion at the measurement site and a required time from the start of taking those postures until the measurement site becomes congested. The processing means obtains the posture of the measurement part from the output signal of the posture detection means, and the duration of the obtained posture exceeds the required time stored in the storage means in association with the type of the posture. In this case, it may be determined that the measurement site is congested. According to this, it can be easily determined whether or not the measurement site is congested.

  The present invention can also be understood as a program invention. The present invention provides a computer with a determination unit that determines whether or not the measurement site is congested from an output signal of a first sensor that detects the posture of the measurement site of a subject's body, and the measurement unit by the measurement unit When it is determined that the blood is congested, based on the output signal of the second sensor that detects the acceleration generated by the force applied to the measurement site, reflected light or transmission of the light emitted toward the measurement site An adaptive filter that generates an estimated waveform of noise superimposed on an output signal of a third sensor that detects light, and generates a pulse wave signal by removing the estimated waveform of noise from the output signal of the third sensor A program for realizing the processing unit is provided.

It is a figure which shows the external appearance of the pulse-wave measuring apparatus which is one Embodiment of this invention. It is a block diagram which shows the electrical structural example of the measuring device. It is a figure which shows the relationship between a test subject's attitude | position and the detected value of the gyro sensor of the measuring apparatus. It is a figure which shows the relationship between a test subject's attitude | position and the detected value of the acceleration sensor of the measuring device. It is a figure which shows an example of the data structure of the stasis degree determination table of the measuring device. It is a figure which shows the result of the measurement which supports the effect by the measuring device. It is a figure which shows the result of the measurement which supports the effect by the measuring device. It is a figure which shows the result of the measurement which supports the effect by the measuring device.

<1. Embodiment>
FIG. 1 is a diagram showing an appearance of a pulse wave measuring apparatus 1 according to an embodiment of the present invention. FIG. 2 is a block diagram showing an example of the electrical configuration of the pulse wave measuring device 1. As shown in FIG. 1, the pulse wave measuring device 1 includes a pulse wave sensor 30, a device main body 10, and a cable 20 that connects them. The pulse wave sensor 30 is a sensor that serves as a light detection unit that optically detects a blood flow in a region between the root of the left index finger of the subject and the second finger joint (hereinafter, a measurement region). The pulse wave sensor 30 has a flat plate shape having a dimension smaller than the width of the measurement site. The pulse wave sensor 30 has both a light emitting element 32a and a light receiving element 32b. The light emitting element 32a is an LED (Light Emitting Diode) having an emission color (for example, blue) having a wavelength that is easily absorbed by blood. The light receiving element 32b is a photodiode. A sensor fixing band 34 is attached to the pulse wave sensor 30.

  The pulse wave sensor 30 is attached to the body of the subject by winding a sensor fixing band 34 around the measurement site so that the light emitting element 32a and the light receiving element 32b are directed to the measurement site. In this mounted state, the light emitting element 32a of the pulse wave sensor 30 irradiates the measurement site with light having an intensity corresponding to the current supplied from the apparatus main body 10 via the cable 20 to the light emitting element 32a. The light emitted from the light emitting element 32a passes through the epidermis of the measurement site and reaches the capillaries of the dermis behind it. A part of the light reaching the blood vessel is absorbed by the blood flowing in the blood vessel. Of the light that has reached the blood vessel, a part of the light that has not been absorbed by the blood in the blood vessel passes through the measurement site, and the rest reaches the light receiving element 32b as reflected light after being scattered in the living tissue. A current RA having a magnitude corresponding to the received light intensity of the reflected light flows through the light receiving element 32b. Here, the blood vessel at the measurement site repeats expansion and contraction in the same cycle as the heartbeat. Then, the amount of light absorption increases and decreases in the same cycle as the blood vessel expansion and contraction, and the intensity of the reflected light also changes accordingly. For this reason, the current RA flowing through the light receiving element 32b has a component indicating a change in the volume of the blood vessel at the measurement site.

  The apparatus body 10 detects the current RA flowing through the light receiving element 32b of the pulse wave sensor 30 while blinking the light emitting element 32a of the pulse wave sensor 30, and removes the noise N due to the influence of the body movement of the subject from the current RA. A pulse wave, which is a waveform indicating a change in the volume of the blood vessel at the measurement site, is measured from the signal from which N is removed.

  The apparatus main body 10 has a shape imitating a wristwatch. A display unit 14 having a rectangular display surface is provided on the surface of the apparatus body 10. The display unit 14 displays a pulse interval, a pulse rate, and the like, which are measurement results by the pulse wave measuring device 1. A button switch 16 is provided on the outer periphery of the housing of the apparatus body 10. The button switch 16 is used to input various instructions such as pulse wave measurement start and measurement end, and measurement result reset. Although not shown in detail in FIG. 1, the display unit 14 and the button switch 16 are connected to the arithmetic processing circuit 120. In addition to the components shown in FIG. 1, the pulse wave measuring device 1 also has an audio output unit connected to the arithmetic processing circuit 120 and housed in the device main body 10. In addition, one end and the other end of the wristband 12 are attached to portions of the outer peripheral portion of the apparatus main body 10 that face each other across the display unit 14. The apparatus body 10 is attached to the body of the subject by winding the wristband 12 around the wrist of the subject (the left wrist in the example shown in FIG. 1).

  As shown in FIG. 2, the apparatus body 10 includes a gyro sensor 150, an acceleration sensor 160, an analog circuit unit 110, an arithmetic processing circuit 120, and a data storage circuit 130. The gyro sensor 150 serves as posture detection means for detecting an inclination angle θ, which is a physical quantity indicating the posture of the wearing part of the apparatus main body 10 in the body of the subject. More specifically, the gyro sensor 150 is formed by an angle formed by the opposing direction of both short sides (the extending direction of the hand on which the apparatus main body 10 is attached) and the horizontal direction at the periphery of the display unit 14 of the apparatus main body 10. Is a tilt angle θ, and a detection signal θA which is an analog signal indicating the angle θ is output.

  For example, as shown in FIG. 3, when the subject takes a posture in which the hand on which the apparatus main body 10 is mounted is directed downward, the angle θ is −90 degrees, and the hand is directed forward. The inclination θ is 0 degree, and the angle θ is +90 degrees when the posture is taken with the hand facing upward. When the angle θ is less than 0 degree, the position of the measurement site is lower than the position of the heart, and the degree of congestion at the measurement site increases. In the present embodiment, it is determined from the output signal θA of the gyro sensor 150 whether the measurement site is congested or ischemic, and the noise N included in the current RA is calculated only while the measurement site is congested. Perform the removal process. Details will be described later.

  The acceleration sensor 160 determines the acceleration generated by the force applied to the acceleration sensor 160 as an acceleration component X in the opposing direction (hand extension direction) of both short sides at the periphery of the display unit 14 of the apparatus body 10 and the display unit 14. The acceleration component Y in the opposite direction (wrist width direction) of the two long sides at the peripheral edge and the acceleration component Z in the direction orthogonal to these two directions (the direction from the display unit 14 toward the wrist) are detected and detected. Detection signals XA, YA, and ZA, which are analog signals indicating the detected acceleration components X, Y, and Z, are output.

Here, gravity G (G = 9.8 m / s 2 ) is applied to the acceleration sensor 160. For example, as shown in FIG. 4, when the subject takes a posture in which the hand on which the apparatus main body 10 is worn is stretched straight down, the acceleration components X, Y, and Z are X = 9.8 m / s 2. , Y = 0 m / s 2 , Z = 0 m / s 2 . In addition, when the subject takes a posture in which the hand on which the apparatus main body 10 is worn is stretched forward with the palm facing inward, the acceleration components X, Y, and Z are X = 0 m / s 2 , Y = 9.8 m / s 2 , Z = 0 m / s 2 .

  In FIG. 2, the analog circuit unit 110 includes a drive circuit 1120, an IV conversion circuit 1112, and an amplifier 1116. The drive circuit 1120 is a circuit that drives the light emitting element 32 a of the pulse wave sensor 30. More specifically, the drive circuit 1120 is supplied with a control signal for controlling the light emission intensity of the light emitting element 32a and the light emission timing from an analog control circuit (not shown). The drive circuit 1120 supplies a current having a magnitude corresponding to the amplitude of the control signal to the light emitting element 32 a of the pulse wave sensor 30. As a result, light is emitted from the light emitting element 32a toward the measurement site, and the current RA flowing through the light receiving element 32b changes according to the received light intensity of the reflected light. As described above, the current RA flowing through the light receiving element 32b has a component indicating a change in the volume of the blood vessel at the measurement site.

  The IV conversion circuit 1112 outputs a voltage RA ′ corresponding to the current RA flowing through the light receiving element 32 b to the amplifier 1116. The amplifier 1116 amplifies the output voltage RA ′ of the IV conversion circuit 1112 and outputs the amplified signal RA ″.

  The data storage circuit 130 stores a stasis level determination table TBL. FIG. 5 is a diagram illustrating an example of a data structure of the blood stasis determination table TBL. In this table TBL, the posture P1 where the angle range RNG of the inclination angle θ of the measurement site is “−90 ≦ θ <−60” and the time T1 required for the measurement site to become congested when the posture P1 is taken. The posture P2 in which the angle range RNG is “−60 ≦ θ <−30”, the time T2 (T2> T1) required for the measurement site to become congested when the posture P2 is taken, and the angle range RNG is “ Three records indicating each pair of a posture P3 where −30 ≦ θ <0 and a time T3 (T3> T2) required for the measurement site to become congested when the posture P3 is taken. These required times are values measured and set in advance for each person to be measured. This table TBL is used to determine the presence or absence of congestion at the measurement site. Details will be described later.

  The arithmetic processing circuit 120 determines whether or not the measurement site is congested from the output signal RA ″ of the amplifier 1116, and when determining that the measurement site is congested, the arithmetic processing circuit 120 outputs the output signals XA, YA, And an estimated waveform of the noise N superimposed on the signal RA ″ based on ZA, and the estimated waveform of the noise N is removed from the signal RA ″ to generate a pulse wave signal PD, and a pulse wave signal PD is generated from the pulse wave signal PD. Measure interval and pulse rate.

  More specifically, the arithmetic processing circuit 120 includes an A / D conversion circuit 1211, 1212, 1213, a CPU (Central Processing Unit) 1215, a volatile memory 1216 such as a RAM (Random Access Memory), and a ROM (Read Only Memory). ) And the like.

  The A / D conversion circuit 1211 converts the output signal RA ″ of the amplifier 1116 into a digital format and outputs the converted signal RD. The A / D conversion circuit 1212 converts the output signal θA of the gyro sensor 150 into a digital format. The A / D conversion circuit 1213 converts the output signals XA, YA, and ZA of the acceleration sensor 160 into a digital format, and outputs the converted signals XD, YD, and ZD.

 The CPU 1215 executes the waveform analysis program stored in the nonvolatile memory 1217 while using the volatile memory 1216 as a work area. This waveform analysis program is a program that causes the CPU 1215 to realize each unit of the determination unit 1221, the adaptive filter processing unit 1222, and the analysis unit 1223. Each of these units 1221, 1222, and 1223 performs the following processing.

  The determination unit 1221 considers that the subject is taking a posture of increasing the congestion of the measurement site while the signal θD indicating the angle θ smaller than 0 degrees is output from the A / D conversion circuit 1212, and performs A / D conversion. While the signal θD indicating the angle θ of 0 degree or more is output from the circuit 1212, it is considered that the subject does not take such a posture. When a signal θD indicating an angle θ smaller than 0 degrees is output from the A / D conversion circuit 1212, the determination unit 1221 determines which posture angle range RNG the angle θ corresponds to in the stasis level determination table TBL. judge. The determination unit 1221 acquires the required time T1 corresponding to the corresponding posture P1, P2, or P3 (for example, the posture P1) from the stasis determination table TBL. Then, the CPU 1215 considers that the subject continues to take the posture P1 while the angle θ indicated by the output signal θD of the subsequent A / D conversion circuit 1212 is within the angle range RNG of the posture P1, and continues the posture P1. When the time exceeds the required time T1, it is considered that the measurement site is congested. Further, when the signal θD indicating the angle θ of 0 degree or more is output from the A / D conversion circuit 1212, it is considered that the congestion is eliminated.

  The adaptive filter processing unit 1222 outputs the output signal RD of the A / D conversion circuit 1211 to the analysis unit 1223 as the pulse wave signal PD while the measurement site is not congested. The adaptive filter processing unit 1222 generates an estimated waveform of the noise N included in the output signal RD of the A / D conversion circuit 1211 by adaptive filter processing while the measurement site is congested, and this estimated waveform. Is subtracted from the output signal RD of the A / D conversion circuit 1211 and the subtraction result is output to the analysis unit 1223 as a pulse wave signal PD.

More specifically, the adaptive filter processing unit 1222 obtains a composite acceleration signal ASD by substituting the output signals XD, YD, and ZD of the acceleration sensor 160 into the following equation, and convolves the filter coefficient sequence w with the composite acceleration signal ASD. The result of the convolution operation is assumed to be an estimated waveform signal WD of noise N.
ASD = (XD 2 + YD 2 + ZD 2 ) 1/2 (1)

  Then, the adaptive filter processing unit 1222 sets the subtraction result obtained by subtracting the signal WD from the output signal RD of the A / D conversion circuit 1211 as the pulse wave signal PD, and reduces the signal PD (that is, reduces noise). The filter coefficient sequence w is updated so that the pulse wave signal PD is not included. The filter coefficient sequence w may be updated in accordance with a known adaptive algorithm such as an LMS (Least Mean Square) algorithm.

  Here, as described above, in this embodiment, when the measurement site is congested, the result of subtracting the processing result of the adaptive filter processing using the output signal of the acceleration sensor 160 from the output signal of the pulse wave sensor 30 is obtained. , Pulse wave signal PD. Thereby, the divergence between the pulse interval which is the peak interval appearing in the pulse wave signal PD and the RR interval which is the peak interval in the R wave of the electrocardiogram is improved. This is also supported by the results of the following measurement conducted by the inventors of the present invention for devising the present invention.

  The inventors of the present application first set the pulse interval at the measurement site to blue and green emission colors for each of the case where the subject is placed in a posture that causes the measurement site to become congested and the posture that does not cause congestion. Each pulse was measured with a pulsometer with a RR, and this pulse interval was compared with the RR interval measured simultaneously in the same subject.

  Waveforms W1B and W1G in FIG. 6 use the output signal DA of the light receiving element 32b as the measurement target signal when the measurement site is irradiated with blue light and green light so that the measurement site is congested. FIG. 4 shows changes with time of pulse interval values measured from signals of respective wavelengths. A waveform W1R shows a change in the RR interval measured simultaneously with the above measurement by the same subject.

  Waveforms W2B and W2G in FIG. 7 use the output signal RA of the light receiving element 32b as a measurement target signal when the measurement site is irradiated with blue and green light by taking a posture such that the measurement site does not become congested. It shows the time-dependent change of the pulse interval value measured from the signal of the wavelength. Waveform W2R shows the change over time of the RR interval measured simultaneously with the above measurement in the same subject.

  Referring to FIGS. 6 and 7, when the measurement site is in a posture that does not cause congestion, the pulse interval and the RR interval are substantially the same, whereas the measurement site is in a posture that causes congestion. It can be seen that, after a while from taking the posture, a large gap occurs between the pulse interval and the RR interval.

  Next, the inventors performed the above-described adaptive filter processing on the output signal RA of the light receiving element 32b, and examined the effect. Waveforms W3B and W3G in FIG. 8 show changes over time in pulse interval values obtained from the waveform obtained as a result of applying the adaptive fill processing described above to waveforms W1B and W1G in FIG. A waveform W3R is the same as W1R, and shows a change with time of the RR interval.

  Referring to FIGS. 6 and 8, the difference between the pulse interval value and the RR interval is improved by performing an adaptive filter process using the output signal RA of the acceleration sensor 160 on the output signal RA of the light receiving element 32b. You can see that

  From the above measurement results, the pulse wave signal PD is obtained by subtracting the processing result of the adaptive filter processing using the output signal of the acceleration sensor 160 from the output signal of the pulse wave sensor 30, so that the pulse interval and the RR interval are obtained. It is confirmed that the divergence is improved.

  In FIG. 2, the analysis unit 1223 detects the pulse interval and the pulse rate from the output signal PD of the adaptive filter processing unit 1222. More specifically, each time a peak appears in the signal PD, the analysis unit 1223 obtains a time difference between the latest peak and the previous peak, and stores this time difference in the data storage circuit 130 as a pulse interval. Let Further, the CPU 1215 counts the number of appearances of peaks in the signal PD every predetermined time (for example, 1 minute), and stores the counted number in the data storage circuit 130 as the pulse rate. The pulse interval and pulse rate stored in the data storage circuit 130 are read from the data storage circuit 130 according to the operation of the button switch 16 and displayed on the display unit 14 as a measurement result.

  As described above, in the present embodiment, when the measurement site is congested, the processing result of the adaptive filter processing using the detection signals XD, YD, ZD of the acceleration sensor 160 is obtained from the detection signal RD of the pulse wave sensor 30. Subtraction is performed, and the subtraction result is used as a pulse wave signal PD indicating a pulse wave. The noise N due to the influence of body movement is removed from the detection signal of the pulse wave sensor 160 by subtracting the processing result of the adaptive filter processing. Therefore, according to the present embodiment, when the measurement site is congested, the situation in which the peak interval appearing in the detection signal of the pulse wave sensor 30 deviates from the RR interval that is the original measurement target does not occur. Therefore, according to the present invention, a measurement result with high accuracy can be obtained regardless of the presence or absence of congestion at the measurement site.

In the present embodiment, a signal to be subtracted from the detection signal of the pulse wave sensor 30 is generated by adaptive filter processing using the detection signals XD, YD, ZD of the acceleration sensor 160. In this adaptive filter process, the filter coefficient sequence w used for the filter process is successively updated so as to simulate the transfer function from the body motion that is the source of the noise N to the measurement site. Therefore, it is possible to efficiently generate an estimated signal of noise N due to the influence of body movement.
In the above-described embodiment, adaptive filter processing for removing moving body noise is performed. In the adaptive filter process, the load on the CPU 1215 becomes heavier than in the normal case, but the adaptive filter process was executed only when the measurement site was congested. For this reason, compared with the case where an adaptive filter process is always performed, the power consumption of the pulse-wave measuring apparatus 1 can be reduced.

<2. Modification>
Although the embodiment of the present invention has been described above, it is needless to say that the following modifications may be added to this embodiment.
(1) In the above embodiment, the light emission color of the light emitting element 32a of the pulse wave sensor 30 is blue, but this light emission color may be green or other colors.

(2) In the adaptive filter processing, the adaptive filter processing unit 1222 in the above embodiment obtains the combined acceleration signal ASD of the output signals XD, YD, and ZD of the acceleration sensor 160, and convolves the filter coefficient sequence w with the combined acceleration signal ASD. Thus, the estimated waveform signal WD was generated. However, the estimated waveform signal WD may be generated by convolving the filter coefficient sequence w with the addition signal obtained by adding one or two of the signals XD, YD, and ZD. Further, instead of subtracting the estimated waveform signal WD from the RD ″ signal, the signals XD, YD, and ZD may be subtracted one by one from the RD ″ signal. For example, first, the signal XD may be subtracted from the RD ″ signal, and the signal YD may be further subtracted from the result. Finally, the signal ZD may be subtracted from the result.

(3) In the above embodiment, the light receiving element 32b of the pulse wave sensor 30 receives the reflected light of the light emitted by the light emitting element 32a of the sensor 30 toward the measurement site, and a signal indicating the received light intensity of the reflected light. Was output as a detection signal RA. However, the light receiving element 32b of the pulse wave sensor 30 receives the transmitted light of the light emitted from the light emitting element 32a of the sensor 30 toward the measurement site, and outputs a signal indicating the received light intensity of the transmitted light as the detection signal RA. May be.

(4) In the above embodiment, the gyro sensor 150 is used as posture detection means for detecting a physical quantity indicating the posture of the measurement site. However, this may be substituted by another type of sensor (for example, a pressure sensor or a geomagnetic sensor) that indicates a physical quantity indicating the posture of the subject. Further, the acceleration sensor 160 may also serve as posture detection means, and the posture of the measurement site may be obtained from the balance of acceleration components in the three-axis directions detected by the sensor 160.

(5) In the above-described embodiment, the pulse wave detection unit 30 is wound around the portion from the root of the index finger of the subject to the second finger joint by the sensor fixing band 34, but the pulse wave detection unit The structure may be such that 30 is wrapped around the upper arm or forearm of the subject with a cuff (armband).
Furthermore, in the above-described embodiment, the pulse wave measuring device 1 includes the device main body 10 attached to the wrist, and the pulse wave detector 30 attached to a portion between the base of the index finger and the second finger joint. These have a structure that is connected via the cable 20, but the pulse wave detection unit 30 and the apparatus main body 10 are configured as one body, and both are configured to be worn on the wrist of the subject by the wristband 12. good. In this case, the cable 20 is not required, and the wristwatch structure in which the apparatus main body 10 and the pulse wave detection unit 30 are integrated has an improved usability of the pulse wave measuring apparatus 1.
In the above-described embodiment, the device main body 10 has a wristwatch structure and is wound around the wrist of the subject by the wristband 12. However, the device main body 10 is provided on an external device such as a mobile phone, and the device main body is provided. Wireless communication may be executed between the mobile phone provided with 10 and the pulse wave detection unit 30. In this case, the pulse wave detection unit 30 may be a cuff (arm band) wound around the wrist, the upper arm, or the forearm. Or it is good also as a structure with which an earlobe is mounted | worn. Since the apparatus body 10 can use the display function, input function, and CPU of the mobile phone, the pulse wave measuring apparatus 1 can be reduced in cost.

  DESCRIPTION OF SYMBOLS 1 ... Pulse wave measuring device, 10 ... Apparatus main body, 12 ... Wristband, 14 ... Display part, 16 ... Button switch, 20 ... Cable, 30 ... Pulse wave sensor, 32a ... Light emitting element, 32b ... Light receiving element, 34 ... Sensor Fixed band, 110 ... analog circuit unit, 1112 ... IV conversion circuit, 1116 ... amplifier, 1120 ... drive circuit, 120 ... arithmetic processing circuit, 1211, 1212, 1213 ... A / D conversion circuit, 1215 ... CPU, 1216 ... volatile , Non-volatile memory, 1221 ... determination unit, 1222 ... adaptive filter processing unit, 1223 ... analysis unit, 130 ... data storage circuit, 150 ... gyro sensor, 160 ... acceleration sensor.

Claims (4)

  1. A means attached to a body part of a subject, irradiating light toward the measurement part of the subject's body, and transmitting the light reflected by the measurement part among the irradiated light or passing through the measurement part Light detecting means for receiving the received light and outputting a signal indicating the received light intensity of the received light;
    Posture detecting means for detecting a physical quantity indicating the posture of the wearing part of the body of the subject of the apparatus mounted on the body of the subject together with the light detecting means or the light detecting means, and outputting a signal indicating the detected physical quantity;
    Acceleration detecting means for detecting an acceleration generated according to a force applied to the measurement site and outputting a signal indicating the detected acceleration;
    It is determined from the output signal of the posture detection means whether or not the measurement site is congested, and when it is determined that the measurement site is congested, the light detection means based on the output signal of the acceleration detection means And a processing unit that generates an estimated waveform of noise superimposed on the output signal and generates a pulse wave signal by removing the estimated waveform of the noise from the output signal of the light detecting unit. Pulse wave measuring device.
  2.   When it is determined that the measurement site is congested, the processing means performs a filter process using a filter coefficient on the output signal of the acceleration detection signal, and outputs the signal after the filter process to the output of the light detection means The adaptive filter processing for updating a filter coefficient used for the filter processing so as to reduce the subtraction result is performed while subtracting from the signal, and the subtraction result is generated as the pulse wave signal. 1. The pulse wave measuring device according to 1.
  3. Comprising a storage means for storing the types of postures that increase congestion at the measurement site and the time required for the measurement site to become congested after starting to take those postures;
    The processing means obtains the posture of the measurement part from the output signal of the posture detection means, and the duration of the obtained posture exceeds the required time stored in the storage means in association with the type of the posture The pulse wave measuring device according to claim 1, wherein the measurement site is determined to be congested.
  4. On the computer,
    A determination unit that determines whether or not the measurement site is congested from an output signal of a first sensor that detects the posture of the measurement site of the body of the subject;
    When the measurement unit determines that the measurement site is congested, irradiation is performed toward the measurement site based on an output signal of a second sensor that detects acceleration generated by a force applied to the measurement site. An estimated waveform of noise superimposed on an output signal of a third sensor that detects reflected light or transmitted light of the generated light is generated, and the estimated waveform of noise is removed from the output signal of the third sensor to generate a pulse. A program that realizes an adaptive filter processing unit that generates a wave signal.
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