JP2014028839A5 - - Google Patents
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- Publication number
- JP2014028839A5 JP2014028839A5 JP2013198117A JP2013198117A JP2014028839A5 JP 2014028839 A5 JP2014028839 A5 JP 2014028839A5 JP 2013198117 A JP2013198117 A JP 2013198117A JP 2013198117 A JP2013198117 A JP 2013198117A JP 2014028839 A5 JP2014028839 A5 JP 2014028839A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- fungal
- bacterial
- colonization
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 102000004457 Granulocyte-Macrophage Colony-Stimulating Factor Human genes 0.000 claims description 28
- 108010017213 Granulocyte-Macrophage Colony-Stimulating Factor Proteins 0.000 claims description 28
- 206010035664 Pneumonia Diseases 0.000 claims description 21
- 230000002538 fungal effect Effects 0.000 claims description 20
- 208000036142 Viral infection Diseases 0.000 claims description 18
- 230000001580 bacterial effect Effects 0.000 claims description 18
- 230000009385 viral infection Effects 0.000 claims description 18
- 206010017533 Fungal infection Diseases 0.000 claims description 17
- 208000031888 Mycoses Diseases 0.000 claims description 17
- 206010006448 Bronchiolitis Diseases 0.000 claims description 15
- 208000023367 bronchiolitis obliterans with obstructive pulmonary disease Diseases 0.000 claims description 9
- 230000000414 obstructive effect Effects 0.000 claims description 9
- 201000003883 Cystic fibrosis Diseases 0.000 claims description 8
- 208000019693 Lung disease Diseases 0.000 claims description 6
- 241000124008 Mammalia Species 0.000 claims description 6
- 201000009267 bronchiectasis Diseases 0.000 claims description 6
- 208000024891 symptom Diseases 0.000 claims description 6
- 208000008745 Healthcare-Associated Pneumonia Diseases 0.000 claims description 5
- 206010006451 bronchitis Diseases 0.000 claims description 5
- 201000000317 pneumocystosis Diseases 0.000 claims description 5
- 230000002685 pulmonary effect Effects 0.000 claims description 5
- 239000007921 spray Substances 0.000 claims description 5
- 208000015181 infectious disease Diseases 0.000 claims description 4
- 210000004072 lung Anatomy 0.000 claims description 4
- 239000000843 powder Substances 0.000 claims description 4
- 230000000241 respiratory effect Effects 0.000 claims description 4
- 239000000725 suspension Substances 0.000 claims description 4
- 239000000443 aerosol Substances 0.000 claims description 3
- 238000013276 bronchoscopy Methods 0.000 claims description 3
- 239000002502 liposome Substances 0.000 claims description 3
- 239000002105 nanoparticle Substances 0.000 claims description 3
- 206010067472 Organising pneumonia Diseases 0.000 claims description 2
- 201000009805 cryptogenic organizing pneumonia Diseases 0.000 claims description 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 20
- 241001673062 Achromobacter xylosoxidans Species 0.000 claims 1
- 241001508003 Mycobacterium abscessus Species 0.000 claims 1
- 208000005384 Pneumocystis Pneumonia Diseases 0.000 claims 1
- 206010073755 Pneumocystis jirovecii pneumonia Diseases 0.000 claims 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- 238000000034 method Methods 0.000 description 26
- 208000035143 Bacterial infection Diseases 0.000 description 9
- 208000022362 bacterial infectious disease Diseases 0.000 description 9
- 206010058467 Lung neoplasm malignant Diseases 0.000 description 6
- 201000005202 lung cancer Diseases 0.000 description 6
- 208000020816 lung neoplasm Diseases 0.000 description 6
- 241000894006 Bacteria Species 0.000 description 4
- 241000233870 Pneumocystis Species 0.000 description 4
- 206010062952 diffuse panbronchiolitis Diseases 0.000 description 4
- 241000233866 Fungi Species 0.000 description 3
- 230000003612 virological effect Effects 0.000 description 3
- 230000007123 defense Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000002708 enhancing effect Effects 0.000 description 2
- 206010061876 Obstruction Diseases 0.000 description 1
- 206010041067 Small cell lung cancer Diseases 0.000 description 1
- 208000009470 Ventilator-Associated Pneumonia Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 210000003123 bronchiole Anatomy 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 208000000587 small cell lung carcinoma Diseases 0.000 description 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86419006P | 2006-11-03 | 2006-11-03 | |
| US60/864,190 | 2006-11-03 | ||
| US94751107P | 2007-07-02 | 2007-07-02 | |
| US60/947,511 | 2007-07-02 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009535569A Division JP2010508365A (ja) | 2006-11-03 | 2007-11-02 | 顆粒球マクロファージコロニー刺激因子を投与することによる肺の宿主防御の増強 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015204558A Division JP6001151B2 (ja) | 2006-11-03 | 2015-10-16 | 顆粒球マクロファージコロニー刺激因子を投与することによる肺の宿主防御の増強 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014028839A JP2014028839A (ja) | 2014-02-13 |
| JP2014028839A5 true JP2014028839A5 (enExample) | 2014-05-15 |
Family
ID=39344625
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009535569A Pending JP2010508365A (ja) | 2006-11-03 | 2007-11-02 | 顆粒球マクロファージコロニー刺激因子を投与することによる肺の宿主防御の増強 |
| JP2013198117A Pending JP2014028839A (ja) | 2006-11-03 | 2013-09-25 | 顆粒球マクロファージコロニー刺激因子を投与することによる肺の宿主防御の増強 |
| JP2015204558A Active JP6001151B2 (ja) | 2006-11-03 | 2015-10-16 | 顆粒球マクロファージコロニー刺激因子を投与することによる肺の宿主防御の増強 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009535569A Pending JP2010508365A (ja) | 2006-11-03 | 2007-11-02 | 顆粒球マクロファージコロニー刺激因子を投与することによる肺の宿主防御の増強 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015204558A Active JP6001151B2 (ja) | 2006-11-03 | 2015-10-16 | 顆粒球マクロファージコロニー刺激因子を投与することによる肺の宿主防御の増強 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20100015217A1 (enExample) |
| EP (1) | EP2094290B1 (enExample) |
| JP (3) | JP2010508365A (enExample) |
| AU (1) | AU2007315402B2 (enExample) |
| BR (1) | BRPI0717958B8 (enExample) |
| CA (1) | CA2668292C (enExample) |
| MX (1) | MX2009004802A (enExample) |
| WO (1) | WO2008052567A2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008116470A1 (en) * | 2007-03-26 | 2008-10-02 | Drugrecure Aps | Enhancing pulmonary host defence via administration of granulocyte- colony stimulating factor |
| EP2688583A4 (en) | 2011-03-22 | 2014-10-29 | Univ Texas | PROTECTION AGAINST INFLUENZA INFECTIONS BY THE GRANULOCYTE MACROPHAGENCOLONIA STIMULATING FACTOR |
| EP2694093B1 (en) | 2011-04-07 | 2018-03-21 | Reponex Pharmaceuticals ApS | Granulocyte-macrophage colony stimulating factor for enhancing pulmonary host defense in acute and chronic radiation syndrome, therapeutic radiation intervention and cancer therapy |
| JP2014529614A (ja) * | 2011-08-29 | 2014-11-13 | トリフォイリウム・エピエス | 放射線により誘発されるまたは化学療法により誘発される肺機能不全の治療または予防のための組成物および方法 |
| WO2013173828A1 (en) | 2012-05-18 | 2013-11-21 | Syracuse University | Controlling bacterial persister cells with host immune factor |
| WO2014012559A1 (en) * | 2012-07-20 | 2014-01-23 | Trifoilium Aps | Granulocyte-macrophage colony-stimulating factor for the treatment of bronchial asthma |
| WO2014096032A1 (en) * | 2012-12-18 | 2014-06-26 | Trifoilium Aps | Gm-csf for treatment of chronic sinusitis |
| US20160000875A1 (en) | 2013-02-20 | 2016-01-07 | Reponex Pharmaceuticals Aps | Gm-csf for treatment of chronic oral mucositis |
| WO2015110536A1 (en) * | 2014-01-22 | 2015-07-30 | Reponex Pharmaceuticals Aps | Granulocyte-macrophage colony-stimulating factor for the treatment and prevention of severe forms of bronchial asthma |
| US20170035850A1 (en) * | 2014-03-07 | 2017-02-09 | Reponex Pharmaceuticals Aps | Compositions for treating lung infections by airway administration |
| EP3145533B8 (en) * | 2014-05-23 | 2024-05-01 | Reponex Pharmaceuticals A/S | Compositions for promoting the healing of wounds |
| EP3171887A1 (en) | 2014-07-24 | 2017-05-31 | Reponex Pharmaceuticals APS | Compositions comprising granulocyte-macrophage colony-stimulating factor for the treatment of inflammatory bowel disease |
| CA3079117A1 (en) | 2017-10-16 | 2019-04-25 | Drugrecure Aps | Gm-csf for treating refractory non-tuberculous mycobacteria infections |
| WO2021188883A1 (en) * | 2020-03-20 | 2021-09-23 | The Regents Of The University Of Colorado, A Body Corporate | Methods and compositions for the treatment of viral disease using granulocyte-macrophage colony-stimulating factor (gm-csf) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235871A (en) * | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| US4501728A (en) * | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
| US5391485A (en) * | 1985-08-06 | 1995-02-21 | Immunex Corporation | DNAs encoding analog GM-CSF molecules displaying resistance to proteases which cleave at adjacent dibasic residues |
| US5162111A (en) * | 1986-07-30 | 1992-11-10 | Grabstein Kenneth H | Treatment of bacterial diseases with granulocyte-macrophage colony stimulating factor |
| US4837028A (en) * | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| US9269067B2 (en) * | 2002-04-04 | 2016-02-23 | Altisource Solutions S.À.R.L. | Method and apparatus for providing selective access to information |
| US7512585B2 (en) | 2002-07-11 | 2009-03-31 | Oracle International Corporation | Support for multiple mechanisms for accessing data stores |
-
2007
- 2007-11-02 EP EP07817959.5A patent/EP2094290B1/en active Active
- 2007-11-02 JP JP2009535569A patent/JP2010508365A/ja active Pending
- 2007-11-02 CA CA2668292A patent/CA2668292C/en active Active
- 2007-11-02 WO PCT/DK2007/050161 patent/WO2008052567A2/en not_active Ceased
- 2007-11-02 MX MX2009004802A patent/MX2009004802A/es active IP Right Grant
- 2007-11-02 US US12/513,215 patent/US20100015217A1/en not_active Abandoned
- 2007-11-02 AU AU2007315402A patent/AU2007315402B2/en active Active
- 2007-11-02 BR BRPI0717958A patent/BRPI0717958B8/pt active IP Right Grant
-
2013
- 2013-09-25 JP JP2013198117A patent/JP2014028839A/ja active Pending
-
2015
- 2015-10-16 JP JP2015204558A patent/JP6001151B2/ja active Active
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