JP2013545472A5 - - Google Patents
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- Publication number
- JP2013545472A5 JP2013545472A5 JP2013541336A JP2013541336A JP2013545472A5 JP 2013545472 A5 JP2013545472 A5 JP 2013545472A5 JP 2013541336 A JP2013541336 A JP 2013541336A JP 2013541336 A JP2013541336 A JP 2013541336A JP 2013545472 A5 JP2013545472 A5 JP 2013545472A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- derivative
- pcr
- cells
- patient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 22
- 102000039446 nucleic acids Human genes 0.000 claims 16
- 108020004707 nucleic acids Proteins 0.000 claims 16
- 150000007523 nucleic acids Chemical class 0.000 claims 16
- 239000002245 particle Substances 0.000 claims 4
- 238000003757 reverse transcription PCR Methods 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 239000007790 solid phase Substances 0.000 claims 3
- 108060003951 Immunoglobulin Proteins 0.000 claims 2
- 230000003321 amplification Effects 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 102000018358 immunoglobulin Human genes 0.000 claims 2
- 238000003199 nucleic acid amplification method Methods 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 238000012163 sequencing technique Methods 0.000 claims 2
- 241000894006 Bacteria Species 0.000 claims 1
- 238000001712 DNA sequencing Methods 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 239000011324 bead Substances 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 210000001124 body fluid Anatomy 0.000 claims 1
- 239000010839 body fluid Substances 0.000 claims 1
- 210000001185 bone marrow Anatomy 0.000 claims 1
- 238000010382 chemical cross-linking Methods 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000035475 disorder Diseases 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- 239000011521 glass Substances 0.000 claims 1
- 238000009396 hybridization Methods 0.000 claims 1
- 230000002209 hydrophobic effect Effects 0.000 claims 1
- 238000003018 immunoassay Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000012071 phase Substances 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41842310P | 2010-12-01 | 2010-12-01 | |
| US61/418,423 | 2010-12-01 | ||
| EP10193291 | 2010-12-01 | ||
| EP10193291.1 | 2010-12-01 | ||
| PCT/EP2011/071433 WO2012072705A1 (en) | 2010-12-01 | 2011-11-30 | Simultaneous detection of biomolecules in single cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013545472A JP2013545472A (ja) | 2013-12-26 |
| JP2013545472A5 true JP2013545472A5 (enExample) | 2014-12-25 |
Family
ID=43638742
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013541336A Pending JP2013545472A (ja) | 2010-12-01 | 2011-11-30 | 単一細胞内の生体分子の同時検出 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20140011698A1 (enExample) |
| EP (1) | EP2646573A1 (enExample) |
| JP (1) | JP2013545472A (enExample) |
| KR (1) | KR20140027915A (enExample) |
| WO (1) | WO2012072705A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2861760B1 (en) * | 2012-06-15 | 2020-01-01 | The Board of Regents of The University of Texas System | High throughput sequencing of multiple transcripts of a single cell |
| EP2906928A4 (en) | 2012-10-15 | 2016-11-09 | Nanocellect Biomedical Inc | SYSTEMS, DEVICES AND METHOD FOR SORTING PARTICLES |
| WO2014144495A1 (en) | 2013-03-15 | 2014-09-18 | Abvitro, Inc. | Single cell bar-coding for antibody discovery |
| US10457088B2 (en) * | 2013-05-13 | 2019-10-29 | Ridgefield Acquisition | Template for self assembly and method of making a self assembled pattern |
| US11952622B2 (en) * | 2013-07-18 | 2024-04-09 | The Johns Hopkins University | Analysis of DNA-containing samples and resolution of mixed contributor DNA samples |
| KR102541849B1 (ko) | 2014-09-15 | 2023-06-09 | 에이비비트로, 엘엘씨 | 고-처리량 뉴클레오티드 라이브러리 서열결정 |
| US10513733B2 (en) | 2015-03-23 | 2019-12-24 | Board Of Regents, The University Of Texas System | High throughout sequencing of paired VH and VL transcripts from B cells secreting antigen-specific antibodies |
| WO2019084538A1 (en) | 2017-10-27 | 2019-05-02 | Board Of Regents, The University Of Texas System | TUMOR SPECIFIC ANTIBODIES, T CELL RECEPTORS AND METHODS OF IDENTIFICATION THEREOF |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6013445A (en) | 1996-06-06 | 2000-01-11 | Lynx Therapeutics, Inc. | Massively parallel signature sequencing by ligation of encoded adaptors |
| US7674632B1 (en) | 2001-12-10 | 2010-03-09 | Zeus Scientific, Inc | Method and composition for homogeneous multiplexed microparticle-based assay |
| CA2513889A1 (en) | 2003-01-29 | 2004-08-19 | 454 Corporation | Double ended sequencing |
| TWI333977B (en) | 2003-09-18 | 2010-12-01 | Symphogen As | Method for linking sequences of interest |
| ES2432040T3 (es) | 2004-01-28 | 2013-11-29 | 454 Life Sciences Corporation | Amplificación de ácido nucleico con emulsión de flujo continuo |
| AU2005216549A1 (en) | 2004-02-27 | 2005-09-09 | President And Fellows Of Harvard College | Polony fluorescent in situ sequencing beads |
| US20060228721A1 (en) | 2005-04-12 | 2006-10-12 | Leamon John H | Methods for determining sequence variants using ultra-deep sequencing |
| CA2615323A1 (en) | 2005-06-06 | 2007-12-21 | 454 Life Sciences Corporation | Paired end sequencing |
| JP5452021B2 (ja) | 2005-12-22 | 2014-03-26 | キージーン ナムローゼ フェンノートシャップ | ハイスループットａｆｌｐ系多型検出法 |
| EP2363205A3 (en) | 2006-01-11 | 2014-06-04 | Raindance Technologies, Inc. | Microfluidic Devices And Methods Of Use In The Formation And Control Of Nanoreactors |
| US8929630B2 (en) * | 2009-03-27 | 2015-01-06 | Life Technologies Corporation | Systems and methods for assessing images |
-
2011
- 2011-11-30 JP JP2013541336A patent/JP2013545472A/ja active Pending
- 2011-11-30 US US13/989,814 patent/US20140011698A1/en not_active Abandoned
- 2011-11-30 KR KR1020137017037A patent/KR20140027915A/ko not_active Ceased
- 2011-11-30 EP EP11790968.9A patent/EP2646573A1/en not_active Withdrawn
- 2011-11-30 WO PCT/EP2011/071433 patent/WO2012072705A1/en not_active Ceased
-
2017
- 2017-07-26 US US15/660,396 patent/US20170322204A1/en not_active Abandoned
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