JP2013545472A - 単一細胞内の生体分子の同時検出 - Google Patents

単一細胞内の生体分子の同時検出 Download PDF

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JP2013545472A
JP2013545472A JP2013541336A JP2013541336A JP2013545472A JP 2013545472 A JP2013545472 A JP 2013545472A JP 2013541336 A JP2013541336 A JP 2013541336A JP 2013541336 A JP2013541336 A JP 2013541336A JP 2013545472 A JP2013545472 A JP 2013545472A
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biomolecule
biological
cell
biomolecules
derivative
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JP2013545472A5 (enExample
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エンツェルスベルガー，マルクス
ボル，アンドレアス
ディーフェンバッハ−シュトライバー，ベアテ
ロート，ギュンター
フォン，シュテッテン，フェリクス
Original Assignee
モルフォシス・アー・ゲー
ハーエスゲー−イーエムイーテー インスティトゥッツ フュル ミクロ ウント インフォルマティオンステヒニーク
アルベルト−ルートヴィヒス−ウニヴェルジテート フライブルク
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
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    • C12Q1/6869—Methods for sequencing
    • G—PHYSICS
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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
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    • C12Q2523/00—Reactions characterised by treatment of reaction samples
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    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/159—Microreactors, e.g. emulsion PCR or sequencing, droplet PCR, microcapsules, i.e. non-liquid containers with a range of different permeability's for different reaction components

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  • Life Sciences & Earth Sciences (AREA)
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  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
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  • Wood Science & Technology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
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  • Bioinformatics & Computational Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2013541336A 2010-12-01 2011-11-30 単一細胞内の生体分子の同時検出 Pending JP2013545472A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US41842310P 2010-12-01 2010-12-01
EP10193291 2010-12-01
US61/418,423 2010-12-01
EP10193291.1 2010-12-01
PCT/EP2011/071433 WO2012072705A1 (en) 2010-12-01 2011-11-30 Simultaneous detection of biomolecules in single cells

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JP2013545472A true JP2013545472A (ja) 2013-12-26
JP2013545472A5 JP2013545472A5 (enExample) 2014-12-25

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US (2) US20140011698A1 (enExample)
EP (1) EP2646573A1 (enExample)
JP (1) JP2013545472A (enExample)
KR (1) KR20140027915A (enExample)
WO (1) WO2012072705A1 (enExample)

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US9708654B2 (en) 2012-06-15 2017-07-18 Board Of Regents, The University Of Texas System High throughput sequencing of multiple transcripts
CN105008895B (zh) 2012-10-15 2019-02-15 纳诺赛莱克特生物医药股份有限公司 颗粒分选的系统、设备和方法
US10119134B2 (en) 2013-03-15 2018-11-06 Abvitro Llc Single cell bar-coding for antibody discovery
US10457088B2 (en) * 2013-05-13 2019-10-29 Ridgefield Acquisition Template for self assembly and method of making a self assembled pattern
US11952622B2 (en) * 2013-07-18 2024-04-09 The Johns Hopkins University Analysis of DNA-containing samples and resolution of mixed contributor DNA samples
SG10201911069WA (en) 2014-09-15 2020-01-30 Abvitro Llc High-throughput nucleotide library sequencing
US10513733B2 (en) 2015-03-23 2019-12-24 Board Of Regents, The University Of Texas System High throughout sequencing of paired VH and VL transcripts from B cells secreting antigen-specific antibodies
WO2019084538A1 (en) 2017-10-27 2019-05-02 Board Of Regents, The University Of Texas System TUMOR SPECIFIC ANTIBODIES, T CELL RECEPTORS AND METHODS OF IDENTIFICATION THEREOF

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US6013445A (en) 1996-06-06 2000-01-11 Lynx Therapeutics, Inc. Massively parallel signature sequencing by ligation of encoded adaptors
US7674632B1 (en) 2001-12-10 2010-03-09 Zeus Scientific, Inc Method and composition for homogeneous multiplexed microparticle-based assay
CA2513535C (en) 2003-01-29 2012-06-12 454 Corporation Bead emulsion nucleic acid amplification
TWI333977B (en) 2003-09-18 2010-12-01 Symphogen As Method for linking sequences of interest
EP1735458B1 (en) 2004-01-28 2013-07-24 454 Life Sciences Corporation Nucleic acid amplification with continuous flow emulsion
AU2005216549A1 (en) 2004-02-27 2005-09-09 President And Fellows Of Harvard College Polony fluorescent in situ sequencing beads
US20060228721A1 (en) 2005-04-12 2006-10-12 Leamon John H Methods for determining sequence variants using ultra-deep sequencing
US7601499B2 (en) 2005-06-06 2009-10-13 454 Life Sciences Corporation Paired end sequencing
DK3404114T3 (da) 2005-12-22 2021-06-28 Keygene Nv Fremgangsmåde til detektering af AFLP-baseret polymorfisme med højt gennemløb
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WO2010111656A2 (en) * 2009-03-27 2010-09-30 Life Technologies Corporation Systems and methods for assessing images

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NATURE REVIEWS GENETICS, JANUARY 2010, VOL.11, P.31-46, JPN6016034364 *

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Publication number Publication date
US20140011698A1 (en) 2014-01-09
KR20140027915A (ko) 2014-03-07
EP2646573A1 (en) 2013-10-09
US20170322204A1 (en) 2017-11-09
WO2012072705A1 (en) 2012-06-07

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