JP2013544095A - 真菌汚染を検出するためのデバイス - Google Patents
真菌汚染を検出するためのデバイス Download PDFInfo
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N33/0027—General constructional details of gas analysers, e.g. portable test equipment concerning the detector
- G01N33/0036—General constructional details of gas analysers, e.g. portable test equipment concerning the detector specially adapted to detect a particular component
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N33/0004—Gaseous mixtures, e.g. polluted air
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- G—PHYSICS
- G01—MEASURING; TESTING
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N33/0031—General constructional details of gas analysers, e.g. portable test equipment concerning the detector comprising two or more sensors, e.g. a sensor array
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Abstract
Description
− 予備濃縮モジュール;
− クロマトグラフィ・マイクロカラムを含む分離モジュール;及び
− センサーのマトリックスを含む検出モジュール
を含む、屋内環境における真菌汚染を検出するためのデバイスに関する。
(1)真菌の種類及びそれらの支持体とは無関係に放出されるが、真菌種によってのみ放出される、1−オクテン−3−オール、1,3−オクタジエン、及びメチル 2−エチルヘキサノエートなどのVOC;
(2)真菌の種類及びその支持体とは無関係に放出されるが、その他の生物源を有することもあり得る、2−メチルフラン、3−メチルフラン、3−メチル−1−ブタノール、2−メチル−1−ブタノール、及びα−ピネンなどのVOC;
(3)真菌の種類及び/又はその支持体に応じて放出される、2−ヘプテン、硫化ジメチル、4−ヘプタノン、2(5H)−フラノン、3−ヘプタノール、及びメトキシベンゼンなどのVOC
を含む。
− 屋内環境からVOCのサンプルを採取するステップ;
− サンプル採取されたVOCを分離するステップ;及び
− 存在するVOCを検出するステップ
を含む方法にも関する。
− 屋内環境からVOCのサンプルを採取するステップ;
− サンプル採取されたVOCを分離するステップ;
− 標的VOCを選択するステップ;及び
− 存在する標的VOCを検出するステップ
を含む。
デバイスの実現
予備濃縮モジュールは、DRIEプロセスを用いてシリコンウエハーにエッチングされたミクロ予備濃縮器を含む。ミクロ予備濃縮器は、幅500μm及び長さ400μmの長方形の断面を有する長さ6cmの20本の溝から構成されており、0.25m2の有効容積を有する。溝には、平均直径120μm、比表面積35m2/g、多孔率2.4cm3/g、及び平均孔径200nmを有する、Tenax(登録商標)TAという名称で販売されている2,6−ジフェニルオキシドをベースにした樹脂の粒子が充填されている。ミクロ予備濃縮器は、第1ウエハーの溝を含む表面に接着結合したシリコンウエハーによって閉鎖されている。
マイクロカラムの較正
較正のために、例1のデバイスのセンサーのマトリックスを、質量分析計に置換した。
真菌汚染の検出
センサーのマトリックスを含む例1のデバイスを、様々な健康な屋内環境、又は様々な発生段階にある真菌汚染を代表する屋内環境に配置した。
Claims (10)
- − 予備濃縮モジュール、
− クロマトグラフィ・マイクロカラムを含む分離モジュール、及び
− センサーのマトリックスを含む検出モジュール
を含む、屋内環境における真菌汚染を検出するためのデバイス。 - 予備濃縮モジュールが吸着材料を含むことを特徴とする、請求項1に記載のデバイス。
- マイクロカラムが1から50mの間の長さを有することを特徴とする、請求項1又は2に記載のデバイス。
- センサーのマトリックスが、真菌由来のVOCに対して親和性を有する少なくとも1種のポリマーを含むことを特徴とする、請求項1から3までのいずれか一項に記載のデバイス。
- 分離モジュールが、標的VOC(揮発性有機化合物)を選択するためのシステムを更に含むことを特徴とする、請求項1から4までのいずれか一項に記載のデバイス。
- 請求項1から5までに記載のデバイスによって実施される、屋内環境における真菌汚染を検出するための方法であって、
− 前記環境からVOCのサンプルを採取するステップ、
− サンプル採取されたVOCを分離するステップ、及び
− 存在するVOCを検出するステップ
を含む方法。 - − 屋内環境からVOCのサンプルを採取するステップ、
− サンプル採取されたVOCを分離するステップ、
− 標的VOCを選択するステップ、及び
− 存在する標的VOCを検出するステップ
を含む、請求項6に記載の方法。 - 標的VOCが、1−オクテン−3−オール、1,3−オクタジエン、メチル 2−エチルヘキサノエート、2−メチルフラン、3−メチルフラン、3−メチル−1−ブタノール、2−メチル−1−ブタノール、α−ピネン、2−ヘプテン、硫化ジメチル、4−ヘプタノン、2(5H)−フラノン、3−ヘプタノール、メトキシベンゼン、及び2−エチルヘキサノール、並びにこれらの混合物からなる群より選択されることを特徴とする、請求項7に記載の方法。
- 真菌汚染の測定が連続的に行われることを特徴とする、請求項7及び8のいずれか一項に記載の方法。
- 屋内環境における真菌汚染を検出するための、請求項1から5までに記載のデバイスの使用。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1059636A FR2967692B1 (fr) | 2010-11-23 | 2010-11-23 | Dispositif de detection d'une contamination fongique |
FR1059636 | 2010-11-23 | ||
PCT/FR2011/052720 WO2012069752A1 (fr) | 2010-11-23 | 2011-11-22 | Dispositif de detection d'une contamination fongique |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2013544095A true JP2013544095A (ja) | 2013-12-12 |
JP5882350B2 JP5882350B2 (ja) | 2016-03-09 |
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EP (1) | EP2643472B1 (ja) |
JP (1) | JP5882350B2 (ja) |
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DE102012017972B4 (de) | 2012-09-12 | 2017-06-22 | Sartorius Stedim Biotech Gmbh | Kombifilter |
EP3385710B1 (en) * | 2017-04-05 | 2021-12-01 | InsightAir Europe | Contamination prevention in a building |
US10760804B2 (en) | 2017-11-21 | 2020-09-01 | Emerson Climate Technologies, Inc. | Humidifier control systems and methods |
US11226128B2 (en) | 2018-04-20 | 2022-01-18 | Emerson Climate Technologies, Inc. | Indoor air quality and occupant monitoring systems and methods |
US11486593B2 (en) | 2018-04-20 | 2022-11-01 | Emerson Climate Technologies, Inc. | Systems and methods with variable mitigation thresholds |
WO2019204790A1 (en) | 2018-04-20 | 2019-10-24 | Emerson Climate Technologies, Inc. | Systems and methods with variable mitigation thresholds |
US11421901B2 (en) | 2018-04-20 | 2022-08-23 | Emerson Climate Technologies, Inc. | Coordinated control of standalone and building indoor air quality devices and systems |
US11994313B2 (en) | 2018-04-20 | 2024-05-28 | Copeland Lp | Indoor air quality sensor calibration systems and methods |
US11371726B2 (en) | 2018-04-20 | 2022-06-28 | Emerson Climate Technologies, Inc. | Particulate-matter-size-based fan control system |
CN109329588B (zh) * | 2018-10-24 | 2022-02-08 | 浙江海洋大学 | 深水网箱养殖用的海水鱼配合饲料 |
US11760169B2 (en) | 2020-08-20 | 2023-09-19 | Denso International America, Inc. | Particulate control systems and methods for olfaction sensors |
US11760170B2 (en) | 2020-08-20 | 2023-09-19 | Denso International America, Inc. | Olfaction sensor preservation systems and methods |
US11828210B2 (en) | 2020-08-20 | 2023-11-28 | Denso International America, Inc. | Diagnostic systems and methods of vehicles using olfaction |
US11932080B2 (en) | 2020-08-20 | 2024-03-19 | Denso International America, Inc. | Diagnostic and recirculation control systems and methods |
US11636870B2 (en) | 2020-08-20 | 2023-04-25 | Denso International America, Inc. | Smoking cessation systems and methods |
US11813926B2 (en) | 2020-08-20 | 2023-11-14 | Denso International America, Inc. | Binding agent and olfaction sensor |
US11881093B2 (en) | 2020-08-20 | 2024-01-23 | Denso International America, Inc. | Systems and methods for identifying smoking in vehicles |
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Also Published As
Publication number | Publication date |
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US10227628B2 (en) | 2019-03-12 |
FR2967692A1 (fr) | 2012-05-25 |
EP2643472B1 (fr) | 2016-03-02 |
WO2012069752A1 (fr) | 2012-05-31 |
CA2817135C (fr) | 2018-05-01 |
CA2817135A1 (fr) | 2012-05-31 |
ES2571354T3 (es) | 2016-05-24 |
PL2643472T3 (pl) | 2016-09-30 |
HUE028951T2 (en) | 2017-02-28 |
DK2643472T3 (en) | 2016-05-30 |
JP5882350B2 (ja) | 2016-03-09 |
EP2643472A1 (fr) | 2013-10-02 |
US20130323781A1 (en) | 2013-12-05 |
FR2967692B1 (fr) | 2016-02-05 |
HRP20160441T1 (hr) | 2016-07-15 |
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